| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P40996 | 536 | SCD2_SCHPO Protein scd2/ral3 OS=Schizosacchar... | 597 | 3e-111 | 350 | 37 | 53 | GO:0071521; C:Cdc42 GTPase complex; TAS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0032488; P:Cdc42 protein signal transduction; TAS:PomBase.::GO:0031137; P:regulation of conjugation with cellular fusion; IMP:PomBase.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; IMP:PomBase. | 2 | P29366 | 551 | BEM1_YEAST Bud emergence protein 1 OS=Sacchar... | 263 | 1e-32 | 135 | 32 | 50 | GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0000131; C:incipient cellular bud site; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD. | | | | | | | | | | GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0000753; P:cell morphogenesis involved in conjugation with cellular fusion; TAS:SGD.::GO:0030010; P:establishment of cell polarity; TAS:SGD. | 3 | A1X283 | 911 | SPD2B_HUMAN SH3 and PX domain-containing prot... | 126 | 0.0000000000002 | 77.8 | 33 | 52 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0002102; C:podosome; ISS:UniProtKB. | | | | | | | | | | GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; ISS:UniProtKB.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:UniProtKB.::GO:0010314; F:phosphatidylinositol-5-phosphate binding; ISS:UniProtKB.::GO:0042169; F:SH2 domain binding; ISS:UniProtKB. | | | | | | | | | | GO:0060612; P:adipose tissue development; ISS:UniProtKB.::GO:0060348; P:bone development; IMP:UniProtKB.::GO:0007154; P:cell communication; IEA:InterPro.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0022617; P:extracellular matrix disassembly; IMP:UniProtKB.::GO:0001654; P:eye development; IMP:UniProtKB.::GO:0007507; P:heart development; IMP:UniProtKB.::GO:0071800; P:podosome assembly; ISS:UniProtKB.::GO:0072657; P:protein localization in membrane; IDA:UniProtKB.::GO:0006801; P:superoxide metabolic process; IDA:UniProtKB. | 4 | A2AAY5 | 908 | SPD2B_MOUSE SH3 and PX domain-containing prot... | 130 | 0.0000000000003 | 76.6 | 31 | 49 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0002102; C:podosome; IDA:UniProtKB. | | | | | | | | | | GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IDA:UniProtKB.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; IMP:UniProtKB.::GO:0070273; F:phosphatidylinositol-4-phosphate binding; IDA:UniProtKB.::GO:0010314; F:phosphatidylinositol-5-phosphate binding; IDA:UniProtKB.::GO:0042169; F:SH2 domain binding; IDA:UniProtKB. | | | | | | | | | | GO:0060612; P:adipose tissue development; IMP:UniProtKB.::GO:0060348; P:bone development; IMP:UniProtKB.::GO:0007154; P:cell communication; IEA:InterPro.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0001654; P:eye development; IMP:UniProtKB.::GO:0007507; P:heart development; IMP:UniProtKB.::GO:0071800; P:podosome assembly; IMP:UniProtKB.::GO:0045600; P:positive regulation of fat cell differentiation; IMP:UniProtKB.::GO:0072657; P:protein localization in membrane; ISS:UniProtKB.::GO:0006801; P:superoxide metabolic process; ISS:UniProtKB. | 5 | Q5TCZ1 | 1133 | SPD2A_HUMAN SH3 and PX domain-containing prot... | 167 | 0.63 | 37 | 22 | 40 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0002102; C:podosome; IDA:UniProtKB. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0006801; P:superoxide metabolic process; IDA:UniProtKB. | 6 | O89032 | 1124 | SPD2A_MOUSE SH3 and PX domain-containing prot... | 167 | 0.54 | 37 | 22 | 40 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0002102; C:podosome; ISS:UniProtKB. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro. | 7 | Q1LYG0 | 1119 | SPD2A_DANRE SH3 and PX domain-containing prot... | 131 | 0.000000002 | 64.3 | 31 | 51 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0002102; C:podosome; ISS:UniProtKB. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0006801; P:superoxide metabolic process; ISS:UniProtKB. | 8 | O77774 | 392 | NCF1_BOVIN Neutrophil cytosol factor 1 OS=Bos... | 84 | 4 | 33.9 | 26 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0006612; P:protein targeting to membrane; ISS:UniProtKB. | 9 | P14598 | 390 | NCF1_HUMAN Neutrophil cytosol factor 1 OS=Hom... | 87 | 0.66 | 36.6 | 26 | 49 | GO:0005829; C:cytosol; TAS:ProtInc.::GO:0043020; C:NADPH oxidase complex; TAS:BHF-UCL.::GO:0032010; C:phagolysosome; TAS:Reactome.::GO:0005625; C:soluble fraction; TAS:ProtInc. | | | | | | | | | | GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0005525; F:GTP binding; TAS:ProtInc.::GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL. | | | | | | | | | | GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0007154; P:cell communication; IEA:InterPro.::GO:0006968; P:cellular defense response; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:BHF-UCL.::GO:0006612; P:protein targeting to membrane; IDA:UniProtKB.::GO:0042554; P:superoxide anion generation; TAS:BHF-UCL. | 10 | Q3UTJ2 | 1180 | SRBS2_MOUSE Sorbin and SH3 domain-containing ... | 91 | 0.024 | 41.6 | 25 | 53 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 11 | O35413 | 1196 | SRBS2_RAT Sorbin and SH3 domain-containing pr... | 89 | 0.052 | 40.4 | 25 | 53 | GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; IDA:RGD. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 12 | A8MVU1 | 366 | NCF1C_HUMAN Putative neutrophil cytosol facto... | 87 | 0.16 | 38.5 | 28 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0016175; F:superoxide-generating NADPH oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro. | 13 | O94875 | 1100 | SRBS2_HUMAN Sorbin and SH3 domain-containing ... | 147 | 0.002 | 45.1 | 22 | 46 | GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005634; C:nucleus; NAS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; NAS:UniProtKB. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; TAS:ProtInc.::GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.::GO:0008307; F:structural constituent of muscle; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 14 | A6NI72 | 391 | NCF1B_HUMAN Putative neutrophil cytosol facto... | 87 | 0.67 | 36.6 | 26 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro. | 15 | Q09014 | 390 | NCF1_MOUSE Neutrophil cytosol factor 1 OS=Mus... | 84 | 3.8 | 33.9 | 26 | 49 | GO:0005829; C:cytosol; TAS:MGI. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:MGI.::GO:0016175; F:superoxide-generating NADPH oxidase activity; IDA:MGI. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0008283; P:cell proliferation; IMP:MGI.::GO:0006968; P:cellular defense response; IMP:MGI.::GO:0050665; P:hydrogen peroxide biosynthetic process; IMP:MGI.::GO:0006954; P:inflammatory response; IMP:MGI.::GO:0006691; P:leukotriene metabolic process; IMP:MGI.::GO:0045986; P:negative regulation of smooth muscle contraction; IMP:MGI.::GO:0070947; P:neutrophil mediated killing of fungus; IMP:MGI.::GO:0070946; P:neutrophil mediated killing of gram-positive bacterium; IMP:MGI.::GO:0006612; P:protein targeting to membrane; ISS:UniProtKB.::GO:0002679; P:respiratory burst involved in defense response; IMP:MGI.::GO:0001878; P:response to yeast; IMP:MGI.::GO:0042554; P:superoxide anion generation; IMP:MGI. | 16 | Q6XZF7 | 1577 | DNMBP_HUMAN Dynamin-binding protein OS=Homo s... | 169 | 0.000001 | 55.5 | 28 | 41 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 17 | Q6TXD4 | 1580 | DNMBP_MOUSE Dynamin-binding protein OS=Mus mu... | 169 | 0.000006 | 53.5 | 27 | 38 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 18 | Q5HYK7 | 790 | SH319_HUMAN SH3 domain-containing protein 19 ... | 166 | 0.12 | 39.3 | 21 | 39 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:BHF-UCL. | | | | | | | | | | GO:0070064; F:proline-rich region binding; IPI:BHF-UCL. | | | | | | | | | | GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.::GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IMP:BHF-UCL.::GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.::GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB. | 19 | Q91X43 | 789 | SH319_MOUSE SH3 domain-containing protein 19 ... | 163 | 0.038 | 40.8 | 21 | 43 | | | | | | | | | | | | | | | | | | | | | GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB. | 20 | Q9BY11 | 444 | PACN1_HUMAN Protein kinase C and casein kinas... | 58 | 0.00005 | 49.7 | 43 | 55 | | | | | | | | | | | GO:0004672; F:protein kinase activity; NAS:UniProtKB. | | | | | | | | | | GO:0006897; P:endocytosis; NAS:UniProtKB. | 21 | Q5R411 | 444 | PACN1_PONAB Protein kinase C and casein kinas... | 58 | 0.00005 | 49.7 | 43 | 55 | | | | | | | | | | | | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 22 | Q61644 | 441 | PACN1_MOUSE Protein kinase C and casein kinas... | 58 | 0.00005 | 49.7 | 43 | 55 | GO:0030137; C:COPI-coated vesicle; IDA:MGI. | | | | | | | | | | GO:0008092; F:cytoskeletal protein binding; IDA:MGI. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0045806; P:negative regulation of endocytosis; IDA:MGI.::GO:0007165; P:signal transduction; TAS:MGI. | 23 | Q9Z0W5 | 441 | PACN1_RAT Protein kinase C and casein kinase ... | 58 | 0.00005 | 49.7 | 43 | 55 | | | | | | | | | | | | | | | | | | | | | GO:0007010; P:cytoskeleton organization; IDA:RGD.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 24 | Q13588 | 217 | GRAP_HUMAN GRB2-related adapter protein OS=Ho... | 55 | 5.4 | 33.1 | 33 | 49 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0007265; P:Ras protein signal transduction; TAS:ProtInc. | 25 | Q8VCM2 | 349 | NOXO1_MOUSE NADPH oxidase organizer 1 OS=Mus ... | 110 | 0.00008 | 48.9 | 32 | 44 | | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0016176; F:superoxide-generating NADPH oxidase activator activity; IDA:MGI. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0022617; P:extracellular matrix disassembly; ISS:UniProtKB.::GO:0006801; P:superoxide metabolic process; IDA:MGI. | 26 | Q8TC17 | 118 | GRAPL_HUMAN GRB2-related adapter protein-like... | 54 | 0.0002 | 45.4 | 35 | 57 | | | | | | | | | | | | | | | | | | | | | | 27 | A7MBI0 | 444 | PACN1_BOVIN Protein kinase C and casein kinas... | 58 | 0.0002 | 47.8 | 41 | 53 | | | | | | | | | | | | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 28 | P97369 | 339 | NCF4_MOUSE Neutrophil cytosol factor 4 OS=Mus... | 94 | 3.4 | 34.3 | 27 | 46 | GO:0005737; C:cytoplasm; IDA:MGI. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro. | 29 | Q925Q9 | 709 | SH3K1_RAT SH3 domain-containing kinase-bindin... | 80 | 0.039 | 40.8 | 35 | 50 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0042981; P:regulation of apoptotic process; TAS:RGD.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB. | 30 | Q4P3H6 | 1207 | SLA1_USTMA Actin cytoskeleton-regulatory comp... | 53 | 0.72 | 36.6 | 30 | 60 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 31 | Q6CHN0 | 1136 | SLA1_YARLI Actin cytoskeleton-regulatory comp... | 63 | 3.7 | 34.3 | 30 | 56 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. |
