rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
331 | P02549 | 2419 | SPTA1_HUMAN Spectrin alpha chain, erythrocyte... | 67 | 4.7 | 34.3 | 27 | 55 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0031235; C:intrinsic to internal side of plasma membrane; TAS:BHF-UCL.::GO:0008091; C:spectrin; TAS:ProtInc.::GO:0014731; C:spectrin-associated cytoskeleton; IDA:BHF-UCL. | | | | | | | | | | GO:0051015; F:actin filament binding; TAS:ProtInc.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc. | | | | | | | | | | GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.::GO:0007015; P:actin filament organization; TAS:ProtInc.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW. | 332 | Q91ZR2 | 614 | SNX18_MOUSE Sorting nexin-18 OS=Mus musculus ... | 56 | 4.8 | 33.9 | 29 | 50 | GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0031234; C:extrinsic to internal side of plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0006897; P:endocytosis; ISS:UniProtKB.::GO:0043547; P:positive regulation of GTPase activity; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 333 | Q9H7D0 | 1870 | DOCK5_HUMAN Dedicator of cytokinesis protein ... | 67 | 4.9 | 34.3 | 30 | 43 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | | 334 | Q9UFD9 | 1639 | RIM3A_HUMAN RIMS-binding protein 3A OS=Homo s... | 75 | 5.3 | 33.9 | 31 | 45 | | | | | | | | | | | | | | | | | | | | | | 335 | P87378 | 296 | CRK_XENLA Adapter molecule crk OS=Xenopus lae... | 55 | 5.3 | 33.5 | 27 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB. | 336 | Q8JHF4 | 677 | MPP5A_DANRE MAGUK p55 subfamily member 5-A OS... | 65 | 5.5 | 33.9 | 34 | 51 | GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 337 | A7EK16 | 1230 | MYO1_SCLS1 Myosin-1 OS=mold) (Whetzelinia scl... | 52 | 5.6 | 33.9 | 27 | 54 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 338 | P42682 | 527 | TXK_MOUSE Tyrosine-protein kinase TXK OS=Mus ... | 50 | 5.7 | 33.5 | 28 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007202; P:activation of phospholipase C activity; IMP:UniProtKB.::GO:0002250; P:adaptive immune response; IMP:UniProtKB.::GO:0032609; P:interferon-gamma production; IGI:MGI.::GO:0032633; P:interleukin-4 production; IGI:MGI.::GO:0001865; P:NK T cell differentiation; IGI:MGI.::GO:0050852; P:T cell receptor signaling pathway; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 339 | P42522 | 1182 | MYOC_DICDI Myosin IC heavy chain OS=Dictyoste... | 34 | 5.8 | 33.9 | 41 | 65 | GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.::GO:0097203; C:phagocytic cup lip; IDA:dictyBase. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0006909; P:phagocytosis; IMP:dictyBase. | 340 | A6NJZ7 | 1639 | RIM3C_HUMAN RIMS-binding protein 3C OS=Homo s... | 75 | 6 | 33.9 | 31 | 45 | | | | | | | | | | | | | | | | | | | | | | 341 | A6NNM3 | 1639 | RIM3B_HUMAN RIMS-binding protein 3B OS=Homo s... | 75 | 6 | 33.9 | 31 | 45 | | | | | | | | | | | | | | | | | | | | | | 342 | Q8T390 | 369 | SH3G3_DROME Endophilin-A OS=Drosophila melano... | 54 | 6.1 | 33.5 | 31 | 54 | GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042171; F:lysophosphatidic acid acyltransferase activity; IDA:FlyBase. | | | | | | | | | | GO:0007269; P:neurotransmitter secretion; NAS:FlyBase.::GO:0050803; P:regulation of synapse structure and activity; IMP:FlyBase.::GO:0048488; P:synaptic vesicle endocytosis; IMP:FlyBase. | 343 | Q8I1I3 | 369 | SH3G3_DROER Endophilin-A OS=Drosophila erecta... | 54 | 6.1 | 33.5 | 31 | 54 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042171; F:lysophosphatidic acid acyltransferase activity; ISS:UniProtKB. | | | | | | | | | | GO:0050803; P:regulation of synapse structure and activity; ISS:UniProtKB.::GO:0048488; P:synaptic vesicle endocytosis; ISS:UniProtKB. | 344 | A2QW93 | 611 | HSE1_ASPNC Class E vacuolar protein-sorting m... | 65 | 6.1 | 33.5 | 31 | 52 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 345 | Q9D0K1 | 405 | PEX13_MOUSE Peroxisomal membrane protein PEX1... | 95 | 6.6 | 33.5 | 32 | 45 | | | | | | | | | | | GO:0000268; F:peroxisome targeting sequence binding; TAS:MGI. | | | | | | | | | | GO:0021795; P:cerebral cortex cell migration; IMP:MGI.::GO:0001561; P:fatty acid alpha-oxidation; IMP:MGI.::GO:0007626; P:locomotory behavior; IMP:MGI.::GO:0060152; P:microtubule-based peroxisome localization; IMP:MGI.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0016560; P:protein import into peroxisome matrix, docking; IMP:MGI.::GO:0001967; P:suckling behavior; IMP:MGI. | 346 | Q96RF0 | 628 | SNX18_HUMAN Sorting nexin-18 OS=Homo sapiens ... | 56 | 6.6 | 33.5 | 29 | 50 | GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0031234; C:extrinsic to internal side of plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0006897; P:endocytosis; IDA:UniProtKB.::GO:0043547; P:positive regulation of GTPase activity; IDA:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 347 | P00526 | 526 | SRC_RSVP Tyrosine-protein kinase transforming... | 111 | 6.6 | 33.5 | 20 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 348 | P25020 | 526 | SRC_RSVH1 Tyrosine-protein kinase transformin... | 111 | 6.7 | 33.5 | 20 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 349 | Q8TE67 | 593 | ES8L3_HUMAN Epidermal growth factor receptor ... | 52 | 6.7 | 33.5 | 35 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 350 | Q75DS3 | 443 | HSE1_ASHGO Class E vacuolar protein-sorting m... | 52 | 7.1 | 33.1 | 29 | 54 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 351 | Q06449 | 215 | PIN3_YEAST [PSI+] inducibility protein 3 OS=S... | 72 | 7.2 | 32.7 | 22 | 49 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IPI:SGD. | 352 | Q99469 | 402 | STAC_HUMAN SH3 and cysteine-rich domain-conta... | 53 | 7.6 | 33.1 | 25 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; TAS:ProtInc. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 353 | A4RE77 | 1212 | MYO1_MAGO7 Myosin-1 OS=blast fungus) (Pyricul... | 35 | 8.3 | 33.1 | 31 | 66 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | GO:0043581; P:mycelium development; IEP:PAMGO_MGG. | 354 | P08032 | 2415 | SPTA1_MOUSE Spectrin alpha chain, erythrocyte... | 95 | 8.5 | 33.5 | 24 | 46 | GO:0032437; C:cuticular plate; IDA:MGI.::GO:0016020; C:membrane; IDA:MGI.::GO:0008091; C:spectrin; IMP:MGI.::GO:0014731; C:spectrin-associated cytoskeleton; IMP:MGI. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0046982; F:protein heterodimerization activity; IPI:MGI. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IMP:MGI.::GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.::GO:0030097; P:hemopoiesis; IMP:MGI.::GO:0002260; P:lymphocyte homeostasis; IMP:MGI.::GO:0007009; P:plasma membrane organization; IMP:MGI.::GO:0006779; P:porphyrin-containing compound biosynthetic process; IMP:MGI.::GO:0042102; P:positive regulation of T cell proliferation; IMP:MGI.::GO:0008360; P:regulation of cell shape; IMP:MGI. | 355 | Q06187 | 659 | BTK_HUMAN Tyrosine-protein kinase BTK OS=Homo... | 52 | 8.6 | 33.1 | 27 | 58 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0045121; C:membrane raft; IDA:HGNC.::GO:0005634; C:nucleus; TAS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; TAS:HGNC.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:UniProtKB.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB. | | | | | | | | | | GO:0002250; P:adaptive immune response; TAS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042113; P:B cell activation; TAS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; TAS:UniProtKB.::GO:0019722; P:calcium-mediated signaling; TAS:HGNC.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:UniProtKB.::GO:0007498; P:mesoderm development; TAS:ProtInc.::GO:0045579; P:positive regulation of B cell differentiation; TAS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:UniProtKB.::GO:0002902; P:regulation of B cell apoptotic process; TAS:UniProtKB.::GO:0002721; P:regulation of B cell cytokine production; TAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 356 | B0BNA1 | 340 | SH3Y1_RAT SH3 domain-containing YSC84-like pr... | 54 | 8.6 | 32.7 | 31 | 61 | | | | | | | | | | | | | | | | | | | | | | 357 | O08641 | 340 | SH3Y1_MOUSE SH3 domain-containing YSC84-like ... | 54 | 8.8 | 32.7 | 31 | 61 | | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 358 | Q6DFH5 | 335 | SH3Y1_XENLA SH3 domain-containing YSC84-like ... | 62 | 9 | 32.7 | 26 | 53 | | | | | | | | | | | | | | | | | | | | | | 359 | A3LXQ8 | 475 | HSE1_PICST Class E vacuolar protein-sorting m... | 90 | 9.6 | 32.7 | 26 | 42 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 360 | P13116 | 532 | SRC2_XENLA Tyrosine-protein kinase Src-2 OS=X... | 59 | 9.7 | 32.7 | 20 | 56 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 361 | P13115 | 532 | SRC1_XENLA Tyrosine-protein kinase Src-1 OS=X... | 59 | 9.7 | 32.7 | 20 | 56 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | |