| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
241 | P31016 | 724 | DLG4_RAT Disks large homolog 4 OS=Rattus norv... | 42 | 0.62 | 37 | 45 | 60 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0032839; C:dendrite cytoplasm; IDA:BHF-UCL.::GO:0060076; C:excitatory synapse; IDA:BHF-UCL.::GO:0044224; C:juxtaparanode region of axon; IDA:MGI.::GO:0014069; C:postsynaptic density; IDA:UniProtKB.::GO:0045211; C:postsynaptic membrane; IDA:MGI.::GO:0019717; C:synaptosome; IDA:UniProtKB. | | | | | | | | | | GO:0031697; F:beta-1 adrenergic receptor binding; IPI:UniProtKB.::GO:0035255; F:ionotropic glutamate receptor binding; IPI:RGD.::GO:0030165; F:PDZ domain binding; IPI:RGD.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0019903; F:protein phosphatase binding; IPI:BHF-UCL.::GO:0097110; F:scaffold protein binding; ISS:BHF-UCL. | | | | | | | | | | GO:0097113; P:alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering; IMP:BHF-UCL.::GO:0060997; P:dendritic spine morphogenesis; IMP:BHF-UCL.::GO:0045184; P:establishment of protein localization; ISS:BHF-UCL.::GO:0035641; P:locomotory exploration behavior; ISS:BHF-UCL.::GO:0002091; P:negative regulation of receptor internalization; IDA:UniProtKB.::GO:0050885; P:neuromuscular process controlling balance; ISS:BHF-UCL.::GO:0045161; P:neuronal ion channel clustering; TAS:UniProtKB.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; IDA:BHF-UCL.::GO:0050806; P:positive regulation of synaptic transmission; IDA:BHF-UCL.::GO:0006461; P:protein complex assembly; ISS:BHF-UCL.::GO:0097120; P:receptor localization to synapse; IMP:BHF-UCL.::GO:2000821; P:regulation of grooming behavior; ISS:BHF-UCL.::GO:2000310; P:regulation of N-methyl-D-aspartate selective glutamate receptor activity; IDA:BHF-UCL.::GO:0006950; P:response to stress; NAS:RGD.::GO:0035176; P:social behavior; ISS:BHF-UCL.::GO:0071625; P:vocalization behavior; ISS:BHF-UCL. | 242 | P46108 | 304 | CRK_HUMAN Adapter molecule crk OS=Homo sapien... | 55 | 0.63 | 36.2 | 27 | 58 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005768; C:endosome; TAS:Reactome.::GO:0005634; C:nucleus; TAS:ProtInc.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB. | | | | | | | | | | GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0048013; P:ephrin receptor signaling pathway; IDA:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0032956; P:regulation of actin cytoskeleton organization; IDA:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; IDA:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc. | 243 | Q64010 | 304 | CRK_MOUSE Adapter molecule crk OS=Mus musculu... | 55 | 0.66 | 36.2 | 27 | 58 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0045309; F:protein phosphorylated amino acid binding; IDA:MGI.::GO:0005070; F:SH3/SH2 adaptor activity; IPI:BHF-UCL. | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB. | 244 | Q8WV41 | 574 | SNX33_HUMAN Sorting nexin-33 OS=Homo sapiens ... | 66 | 0.67 | 36.6 | 29 | 55 | | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro. | 245 | O55043 | 646 | ARHG7_RAT Rho guanine nucleotide exchange fac... | 40 | 0.68 | 36.6 | 38 | 63 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:RGD.::GO:0030426; C:growth cone; IDA:RGD.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0043615; P:astrocyte cell migration; IMP:RGD.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IDA:RGD. | 246 | Q62662 | 506 | FRK_RAT Tyrosine-protein kinase FRK OS=Rattus... | 154 | 4.9 | 33.9 | 23 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0030154; P:cell differentiation; IEP:RGD. | 247 | O94868 | 740 | FCSD2_HUMAN FCH and double SH3 domains protei... | 68 | 0.71 | 36.6 | 31 | 47 | | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 248 | Q5PYH7 | 881 | DLG2_DANRE Disks large homolog 2 OS=Danio rer... | 42 | 0.72 | 36.6 | 43 | 60 | | | | | | | | | | | | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.::GO:0050808; P:synapse organization; NAS:UniProtKB.::GO:0007268; P:synaptic transmission; NAS:UniProtKB. | 249 | Q15080 | 339 | NCF4_HUMAN Neutrophil cytosol factor 4 OS=Hom... | 55 | 1.9 | 35 | 33 | 55 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0043020; C:NADPH oxidase complex; IDA:UniProtKB.::GO:0032010; C:phagolysosome; TAS:Reactome. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0046983; F:protein dimerization activity; TAS:UniProtKB. | | | | | | | | | | GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0007154; P:cell communication; IEA:InterPro.::GO:0006955; P:immune response; TAS:UniProtKB.::GO:0055114; P:oxidation-reduction process; TAS:UniProtKB. | 250 | O60229 | 2985 | KALRN_HUMAN Kalirin OS=Homo sapiens (Human). ... | 114 | 0.77 | 36.6 | 26 | 42 | GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007399; P:nervous system development; ISS:HGNC.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0016192; P:vesicle-mediated transport; TAS:ProtInc. | 251 | A1DFN5 | 603 | HSE1_NEOFI Class E vacuolar protein-sorting m... | 85 | 0.8 | 36.6 | 29 | 52 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 252 | Q9NQ75 | 786 | CASS4_HUMAN Cas scaffolding protein family me... | 82 | 0.84 | 36.6 | 29 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 253 | P53281 | 241 | LSB1_YEAST LAS seventeen-binding protein 1 OS... | 81 | 0.85 | 35.8 | 23 | 52 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 254 | Q9QY53 | 687 | NPHP1_MOUSE Nephrocystin-1 OS=Mus musculus (M... | 53 | 0.87 | 36.2 | 34 | 57 | GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0035085; C:cilium axoneme; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.::GO:0031514; C:motile cilium; ISS:UniProtKB.::GO:0032391; C:photoreceptor connecting cilium; IDA:UniProtKB.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0030030; P:cell projection organization; IMP:UniProtKB.::GO:0034613; P:cellular protein localization; IGI:UniProtKB.::GO:0035845; P:photoreceptor cell outer segment organization; IGI:UniProtKB.::GO:0060041; P:retina development in camera-type eye; IMP:UniProtKB.::GO:0048515; P:spermatid differentiation; IMP:UniProtKB. | 255 | P19878 | 526 | NCF2_HUMAN Neutrophil cytosol factor 2 OS=Hom... | 70 | 0.88 | 36.2 | 27 | 50 | GO:0043020; C:NADPH oxidase complex; TAS:BHF-UCL.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0032010; C:phagolysosome; TAS:Reactome. | | | | | | | | | | GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB. | | | | | | | | | | GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006968; P:cellular defense response; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:BHF-UCL.::GO:0045730; P:respiratory burst; TAS:BHF-UCL.::GO:0042554; P:superoxide anion generation; TAS:BHF-UCL. | 256 | Q9US59 | 140 | SKB5_SCHPO Shk1 kinase-binding protein 5 OS=S... | 73 | 0.92 | 34.7 | 22 | 51 | GO:0005783; C:endoplasmic reticulum; IDA:PomBase. | | | | | | | | | | GO:0019901; F:protein kinase binding; IDA:UniProtKB. | | | | | | | | | | | 257 | Q9ES28 | 862 | ARHG7_MOUSE Rho guanine nucleotide exchange f... | 40 | 0.94 | 36.2 | 38 | 63 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 258 | A1A4S6 | 786 | RHG10_HUMAN Rho GTPase-activating protein 10 ... | 76 | 1 | 36.2 | 30 | 47 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 259 | P50478 | 682 | AMPH_CHICK Amphiphysin OS=Gallus gallus (Chic... | 79 | 1.1 | 36.2 | 33 | 51 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:AgBase.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0019717; C:synaptosome; IDA:AgBase. | | | | | | | | | | | | | | | | | | | | | 260 | Q3USJ8 | 740 | FCSD2_MOUSE FCH and double SH3 domains protei... | 67 | 1.1 | 36.2 | 30 | 48 | | | | | | | | | | | | | | | | | | | | | | 261 | Q08DP6 | 785 | RHG10_BOVIN Rho GTPase-activating protein 10 ... | 72 | 1.1 | 36.2 | 32 | 49 | GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 262 | Q4WHP5 | 584 | HSE1_ASPFU Class E vacuolar protein-sorting m... | 88 | 1.1 | 36.2 | 30 | 51 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 263 | O77506 | 263 | LASP1_RABIT LIM and SH3 domain protein 1 OS=O... | 52 | 1.1 | 35.4 | 27 | 54 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006811; P:ion transport; IEA:UniProtKB-KW. | 264 | Q1DLP2 | 1251 | MYO1_COCIM Myosin-1 OS=Coccidioides immitis (... | 58 | 1.1 | 36.2 | 29 | 50 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 265 | Q60598 | 546 | SRC8_MOUSE Src substrate cortactin OS=Mus mus... | 81 | 1.1 | 35.8 | 27 | 46 | GO:0005938; C:cell cortex; IDA:MGI.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0001726; C:ruffle; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | | 266 | Q8R1B0 | 408 | STAC2_MOUSE SH3 and cysteine-rich domain-cont... | 59 | 1.2 | 35.8 | 27 | 53 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 267 | Q62421 | 347 | SH3G3_MOUSE Endophilin-A3 OS=Mus musculus (Mo... | 58 | 1.2 | 35.4 | 28 | 48 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 268 | A4RF61 | 718 | HSE1_MAGO7 Class E vacuolar protein-sorting m... | 68 | 1.2 | 35.8 | 29 | 46 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 269 | Q6WKZ7 | 506 | NOSTN_MOUSE Nostrin OS=Mus musculus (Mouse). ... | 60 | 1.2 | 35.8 | 28 | 52 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI. | 270 | Q7TNF8 | 1846 | RIMB1_MOUSE Peripheral-type benzodiazepine re... | 113 | 1.2 | 36.2 | 31 | 42 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 271 | Q10199 | 670 | IMP2_SCHPO Septation protein imp2 OS=Schizosa... | 58 | 1.3 | 35.8 | 36 | 52 | GO:0005826; C:actomyosin contractile ring; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0005515; F:protein binding; IPI:PomBase. | | | | | | | | | | GO:0000915; P:cytokinesis, actomyosin contractile ring assembly; IMP:PomBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. |
