| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
211 | Q5R5W0 | 261 | LASP1_PONAB LIM and SH3 domain protein 1 OS=P... | 52 | 0.39 | 37 | 29 | 54 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006811; P:ion transport; IEA:UniProtKB-KW. | 212 | Q12965 | 1108 | MYO1E_HUMAN Unconventional myosin-Ie OS=Homo ... | 49 | 0.4 | 37.7 | 43 | 55 | GO:0005912; C:adherens junction; ISS:UniProtKB.::GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; TAS:UniProtKB. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042623; F:ATPase activity, coupled; IDA:UniProtKB.::GO:0005516; F:calmodulin binding; IDA:UniProtKB.::GO:0000146; F:microfilament motor activity; TAS:UniProtKB.::GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB. | | | | | | | | | | GO:0030048; P:actin filament-based movement; TAS:UniProtKB.::GO:0006897; P:endocytosis; IMP:UniProtKB.::GO:0032836; P:glomerular basement membrane development; ISS:UniProtKB.::GO:0003094; P:glomerular filtration; ISS:UniProtKB.::GO:0072015; P:glomerular visceral epithelial cell development; ISS:UniProtKB. | 213 | Q28C55 | 927 | DLG1_XENTR Disks large homolog 1 OS=Xenopus t... | 42 | 0.4 | 37.4 | 40 | 60 | GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 214 | E9Q634 | 1107 | MYO1E_MOUSE Unconventional myosin-Ie OS=Mus m... | 49 | 0.41 | 37.4 | 43 | 55 | GO:0005912; C:adherens junction; IDA:UniProtKB.::GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051015; F:actin filament binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042623; F:ATPase activity, coupled; ISS:UniProtKB.::GO:0005516; F:calmodulin binding; ISS:UniProtKB.::GO:0003774; F:motor activity; IEA:InterPro.::GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB. | | | | | | | | | | GO:0006897; P:endocytosis; ISS:UniProtKB.::GO:0032836; P:glomerular basement membrane development; IMP:UniProtKB.::GO:0003094; P:glomerular filtration; IMP:UniProtKB.::GO:0072015; P:glomerular visceral epithelial cell development; IMP:UniProtKB.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IMP:MGI.::GO:0035166; P:post-embryonic hemopoiesis; IMP:MGI.::GO:0001570; P:vasculogenesis; IMP:MGI. | 215 | Q14847 | 261 | LASP1_HUMAN LIM and SH3 domain protein 1 OS=H... | 52 | 0.42 | 36.6 | 29 | 54 | GO:0030864; C:cortical actin cytoskeleton; ISS:UniProtKB. | | | | | | | | | | GO:0015075; F:ion transmembrane transporter activity; ISS:UniProtKB.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 216 | Q9V9J3 | 517 | SRC42_DROME Tyrosine-protein kinase Src42A OS... | 40 | 0.42 | 37.4 | 43 | 68 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0051017; P:actin filament bundle assembly; IMP:FlyBase.::GO:0043277; P:apoptotic cell clearance; IMP:FlyBase.::GO:0048749; P:compound eye development; IMP:FlyBase.::GO:0007395; P:dorsal closure, spreading of leading edge cells; IMP:FlyBase.::GO:0046529; P:imaginal disc fusion, thorax closure; IMP:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.::GO:0007254; P:JNK cascade; TAS:FlyBase.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; IGI:FlyBase.::GO:0007424; P:open tracheal system development; IMP:FlyBase.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IMP:FlyBase.::GO:0007435; P:salivary gland morphogenesis; IMP:FlyBase.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IGI:FlyBase.::GO:0006099; P:tricarboxylic acid cycle; IDA:FlyBase. | 217 | Q6FN49 | 450 | HSE1_CANGA Class E vacuolar protein-sorting m... | 54 | 1 | 35.8 | 33 | 54 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 218 | Q61792 | 263 | LASP1_MOUSE LIM and SH3 domain protein 1 OS=M... | 51 | 0.42 | 36.6 | 29 | 55 | GO:0030864; C:cortical actin cytoskeleton; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IDA:MGI. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:MGI.::GO:0015075; F:ion transmembrane transporter activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 219 | O00750 | 1634 | P3C2B_HUMAN Phosphatidylinositol 4-phosphate ... | 103 | 0.42 | 37.4 | 25 | 46 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; NAS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro.::GO:0005886; C:plasma membrane; NAS:UniProtKB. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IEA:InterPro.::GO:0035005; F:1-phosphatidylinositol-4-phosphate 3-kinase activity; NAS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro. | 220 | Q62108 | 724 | DLG4_MOUSE Disks large homolog 4 OS=Mus muscu... | 42 | 0.43 | 37.4 | 45 | 60 | GO:0032281; C:alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex; IDA:MGI.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0032839; C:dendrite cytoplasm; ISS:BHF-UCL.::GO:0060076; C:excitatory synapse; IDA:BHF-UCL.::GO:0031234; C:extrinsic to internal side of plasma membrane; IDA:MGI.::GO:0044224; C:juxtaparanode region of axon; IDA:MGI.::GO:0044306; C:neuron projection terminus; IDA:MGI.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.::GO:0008021; C:synaptic vesicle; IDA:MGI.::GO:0019717; C:synaptosome; ISS:UniProtKB. | | | | | | | | | | GO:0035255; F:ionotropic glutamate receptor binding; IPI:BHF-UCL.::GO:0042043; F:neurexin family protein binding; NAS:UniProtKB.::GO:0008022; F:protein C-terminus binding; NAS:UniProtKB.::GO:0097110; F:scaffold protein binding; IPI:BHF-UCL.::GO:0005198; F:structural molecule activity; NAS:UniProtKB. | | | | | | | | | | GO:0097113; P:alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering; ISS:BHF-UCL.::GO:0060997; P:dendritic spine morphogenesis; IDA:BHF-UCL.::GO:0045184; P:establishment of protein localization; ISS:BHF-UCL.::GO:0035641; P:locomotory exploration behavior; IMP:BHF-UCL.::GO:0050885; P:neuromuscular process controlling balance; IMP:BHF-UCL.::GO:0006461; P:protein complex assembly; ISS:BHF-UCL.::GO:0097120; P:receptor localization to synapse; ISS:BHF-UCL.::GO:2000821; P:regulation of grooming behavior; IMP:BHF-UCL.::GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IGI:MGI.::GO:0042220; P:response to cocaine; NAS:UniProtKB.::GO:0035176; P:social behavior; IMP:BHF-UCL.::GO:0016188; P:synaptic vesicle maturation; IDA:MGI.::GO:0071625; P:vocalization behavior; IMP:BHF-UCL. | 221 | A2CG49 | 2964 | KALRN_MOUSE Kalirin OS=Mus musculus (Mouse). ... | 114 | 0.44 | 37.7 | 26 | 43 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 222 | Q8N2Y8 | 1516 | RUSC2_HUMAN Iporin OS=Homo sapiens (Human). G... | 90 | 0.44 | 37.4 | 29 | 52 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 223 | O75886 | 525 | STAM2_HUMAN Signal transducing adapter molecu... | 93 | 0.65 | 36.6 | 29 | 49 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0016197; P:endosome transport; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome. | 224 | Q8WUF5 | 828 | IASPP_HUMAN RelA-associated inhibitor OS=Homo... | 64 | 0.45 | 37.4 | 34 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; TAS:ProtInc. | | | | | | | | | | GO:0003714; F:transcription corepressor activity; TAS:ProtInc.::GO:0008134; F:transcription factor binding; TAS:ProtInc. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 225 | P13395 | 2415 | SPTCA_DROME Spectrin alpha chain OS=Drosophil... | 69 | 0.46 | 37.4 | 28 | 58 | GO:0016323; C:basolateral plasma membrane; IDA:FlyBase.::GO:0005938; C:cell cortex; IDA:FlyBase.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0045169; C:fusome; IDA:FlyBase.::GO:0005794; C:Golgi apparatus; IDA:FlyBase.::GO:0031594; C:neuromuscular junction; IDA:FlyBase.::GO:0045170; C:spectrosome; IDA:FlyBase. | | | | | | | | | | GO:0003779; F:actin binding; IDA:FlyBase.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; IDA:FlyBase. | | | | | | | | | | GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.::GO:0016199; P:axon midline choice point recognition; IGI:FlyBase.::GO:0007417; P:central nervous system development; IMP:FlyBase.::GO:0045478; P:fusome organization; TAS:FlyBase.::GO:0030727; P:germarium-derived female germ-line cyst formation; IMP:FlyBase.::GO:0007294; P:germarium-derived oocyte fate determination; IMP:FlyBase.::GO:0042062; P:long-term strengthening of neuromuscular junction; IMP:FlyBase.::GO:0048790; P:maintenance of presynaptic active zone structure; IDA:FlyBase.::GO:0007026; P:negative regulation of microtubule depolymerization; IMP:FlyBase.::GO:0007274; P:neuromuscular synaptic transmission; IMP:FlyBase.::GO:0007308; P:oocyte construction; IMP:FlyBase.::GO:0030707; P:ovarian follicle cell development; TAS:FlyBase.::GO:0007009; P:plasma membrane organization; TAS:FlyBase.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0030721; P:spectrosome organization; TAS:FlyBase. | 226 | A1Y2K1 | 537 | FYN_PIG Tyrosine-protein kinase Fyn OS=Sus sc... | 38 | 0.51 | 37 | 39 | 68 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 227 | P39688 | 537 | FYN_MOUSE Tyrosine-protein kinase Fyn OS=Mus ... | 90 | 0.7 | 36.6 | 21 | 47 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0044325; F:ion channel binding; IPI:BHF-UCL.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0015631; F:tubulin binding; IDA:MGI. | | | | | | | | | | GO:0050798; P:activated T cell proliferation; IMP:MGI.::GO:0048813; P:dendrite morphogenesis; IMP:MGI.::GO:0050966; P:detection of mechanical stimulus involved in sensory perception of pain; IMP:MGI.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0042552; P:myelination; TAS:MGI.::GO:0010629; P:negative regulation of gene expression; IMP:BHF-UCL.::GO:0042177; P:negative regulation of protein catabolic process; IMP:MGI.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:MGI.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0008360; P:regulation of cell shape; IDA:MGI.::GO:0045471; P:response to ethanol; IGI:MGI. | 228 | A0JNB0 | 537 | FYN_BOVIN Tyrosine-protein kinase Fyn OS=Bos ... | 90 | 0.54 | 37 | 21 | 47 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 229 | Q62844 | 537 | FYN_RAT Tyrosine-protein kinase Fyn OS=Rattus... | 90 | 0.68 | 36.6 | 21 | 47 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005792; C:microsome; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042609; F:CD4 receptor binding; IPI:RGD.::GO:0042610; F:CD8 receptor binding; IPI:RGD.::GO:0001948; F:glycoprotein binding; IPI:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0051428; F:peptide hormone receptor binding; IPI:RGD.::GO:0043548; F:phosphatidylinositol 3-kinase binding; IDA:RGD.::GO:0042608; F:T cell receptor binding; IDA:RGD. | | | | | | | | | | GO:0071363; P:cellular response to growth factor stimulus; IEP:RGD.::GO:0071375; P:cellular response to peptide hormone stimulus; IEP:RGD.::GO:0035235; P:ionotropic glutamate receptor signaling pathway; TAS:RGD.::GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IMP:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0042493; P:response to drug; IEP:RGD. | 230 | Q99MZ8 | 263 | LASP1_RAT LIM and SH3 domain protein 1 OS=Rat... | 51 | 0.51 | 36.6 | 29 | 55 | GO:0030864; C:cortical actin cytoskeleton; IDA:UniProtKB. | | | | | | | | | | GO:0015075; F:ion transmembrane transporter activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 231 | Q64434 | 451 | PTK6_MOUSE Protein-tyrosine kinase 6 OS=Mus m... | 79 | 0.51 | 37 | 34 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:MGI.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MGI. | | | | | | | | | | GO:0060575; P:intestinal epithelial cell differentiation; IMP:UniProtKB.::GO:0045926; P:negative regulation of growth; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0042503; P:tyrosine phosphorylation of Stat3 protein; ISS:UniProtKB.::GO:0042506; P:tyrosine phosphorylation of Stat5 protein; ISS:UniProtKB. | 232 | P06241 | 537 | FYN_HUMAN Tyrosine-protein kinase Fyn OS=Homo... | 90 | 0.67 | 36.6 | 21 | 47 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005768; C:endosome; IDA:HGNC.::GO:0005886; C:plasma membrane; IDA:HGNC. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0001948; F:glycoprotein binding; IPI:BHF-UCL.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; NAS:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0006816; P:calcium ion transport; NAS:UniProtKB.::GO:0007631; P:feeding behavior; TAS:ProtInc.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; TAS:ProtInc.::GO:0007612; P:learning; TAS:ProtInc.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; IDA:UniProtKB.::GO:0016032; P:viral reproduction; TAS:Reactome. | 233 | P78352 | 724 | DLG4_HUMAN Disks large homolog 4 OS=Homo sapi... | 42 | 0.51 | 37 | 45 | 60 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0030863; C:cortical cytoskeleton; IDA:UniProtKB.::GO:0032839; C:dendrite cytoplasm; ISS:BHF-UCL.::GO:0030666; C:endocytic vesicle membrane; TAS:Reactome.::GO:0060076; C:excitatory synapse; ISS:BHF-UCL.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0045211; C:postsynaptic membrane; IDA:UniProtKB.::GO:0019717; C:synaptosome; ISS:UniProtKB. | | | | | | | | | | GO:0035255; F:ionotropic glutamate receptor binding; ISS:BHF-UCL.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0097110; F:scaffold protein binding; ISS:BHF-UCL. | | | | | | | | | | GO:0097113; P:alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering; ISS:BHF-UCL.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0060997; P:dendritic spine morphogenesis; ISS:BHF-UCL.::GO:0045184; P:establishment of protein localization; IDA:BHF-UCL.::GO:0007612; P:learning; TAS:ProtInc.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.::GO:0050806; P:positive regulation of synaptic transmission; ISS:BHF-UCL.::GO:0006461; P:protein complex assembly; IDA:BHF-UCL.::GO:0097120; P:receptor localization to synapse; ISS:BHF-UCL.::GO:2000310; P:regulation of N-methyl-D-aspartate selective glutamate receptor activity; ISS:BHF-UCL.::GO:0007165; P:signal transduction; TAS:ProtInc. | 234 | Q2KJA1 | 368 | SH3G1_BOVIN Endophilin-A2 OS=Bos taurus (Bovi... | 57 | 0.52 | 36.6 | 30 | 53 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 235 | Q63356 | 1107 | MYO1E_RAT Unconventional myosin-Ie OS=Rattus ... | 49 | 0.53 | 37.4 | 43 | 55 | GO:0005912; C:adherens junction; ISS:UniProtKB.::GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051015; F:actin filament binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042623; F:ATPase activity, coupled; ISS:UniProtKB.::GO:0005516; F:calmodulin binding; ISS:UniProtKB.::GO:0003774; F:motor activity; IEA:InterPro.::GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB.::GO:0032403; F:protein complex binding; IDA:RGD. | | | | | | | | | | GO:0006897; P:endocytosis; ISS:UniProtKB.::GO:0032836; P:glomerular basement membrane development; ISS:UniProtKB.::GO:0003094; P:glomerular filtration; ISS:UniProtKB.::GO:0072015; P:glomerular visceral epithelial cell development; ISS:UniProtKB. | 236 | O43125 | 296 | CSH3_SCHPO Protein csh3 OS=Schizosaccharomyce... | 55 | 0.55 | 36.6 | 35 | 53 | GO:0005737; C:cytoplasm; IDA:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:PomBase. | 237 | Q99961 | 368 | SH3G1_HUMAN Endophilin-A2 OS=Homo sapiens (Hu... | 57 | 0.57 | 36.6 | 30 | 53 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; TAS:ProtInc. | 238 | Q14155 | 803 | ARHG7_HUMAN Rho guanine nucleotide exchange f... | 63 | 0.57 | 37 | 30 | 52 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0043005; C:neuron projection; IDA:BHF-UCL.::GO:0043025; C:neuronal cell body; IDA:BHF-UCL.::GO:0043234; C:protein complex; IDA:UniProtKB.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0043547; P:positive regulation of GTPase activity; IDA:BHF-UCL.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 239 | Q922K9 | 512 | FRK_MOUSE Tyrosine-protein kinase FRK OS=Mus ... | 76 | 0.59 | 37 | 26 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 240 | Q63768 | 304 | CRK_RAT Adapter molecule crk OS=Rattus norveg... | 55 | 0.6 | 36.6 | 27 | 58 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; TAS:RGD.::GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0051270; P:regulation of cellular component movement; TAS:RGD.::GO:0035020; P:regulation of Rac protein signal transduction; IMP:RGD.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB. | 241 | P31016 | 724 | DLG4_RAT Disks large homolog 4 OS=Rattus norv... | 42 | 0.62 | 37 | 45 | 60 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0032839; C:dendrite cytoplasm; IDA:BHF-UCL.::GO:0060076; C:excitatory synapse; IDA:BHF-UCL.::GO:0044224; C:juxtaparanode region of axon; IDA:MGI.::GO:0014069; C:postsynaptic density; IDA:UniProtKB.::GO:0045211; C:postsynaptic membrane; IDA:MGI.::GO:0019717; C:synaptosome; IDA:UniProtKB. | | | | | | | | | | GO:0031697; F:beta-1 adrenergic receptor binding; IPI:UniProtKB.::GO:0035255; F:ionotropic glutamate receptor binding; IPI:RGD.::GO:0030165; F:PDZ domain binding; IPI:RGD.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0019903; F:protein phosphatase binding; IPI:BHF-UCL.::GO:0097110; F:scaffold protein binding; ISS:BHF-UCL. | | | | | | | | | | GO:0097113; P:alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering; IMP:BHF-UCL.::GO:0060997; P:dendritic spine morphogenesis; IMP:BHF-UCL.::GO:0045184; P:establishment of protein localization; ISS:BHF-UCL.::GO:0035641; P:locomotory exploration behavior; ISS:BHF-UCL.::GO:0002091; P:negative regulation of receptor internalization; IDA:UniProtKB.::GO:0050885; P:neuromuscular process controlling balance; ISS:BHF-UCL.::GO:0045161; P:neuronal ion channel clustering; TAS:UniProtKB.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; IDA:BHF-UCL.::GO:0050806; P:positive regulation of synaptic transmission; IDA:BHF-UCL.::GO:0006461; P:protein complex assembly; ISS:BHF-UCL.::GO:0097120; P:receptor localization to synapse; IMP:BHF-UCL.::GO:2000821; P:regulation of grooming behavior; ISS:BHF-UCL.::GO:2000310; P:regulation of N-methyl-D-aspartate selective glutamate receptor activity; IDA:BHF-UCL.::GO:0006950; P:response to stress; NAS:RGD.::GO:0035176; P:social behavior; ISS:BHF-UCL.::GO:0071625; P:vocalization behavior; ISS:BHF-UCL. |
