| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
151 | P17713 | 509 | STK_HYDVU Tyrosine-protein kinase STK OS=Hydr... | 58 | 0.096 | 39.3 | 29 | 53 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 152 | P24135 | 1265 | PLCG2_RAT 1-phosphatidylinositol 4,5-bisphosp... | 33 | 0.098 | 39.7 | 42 | 70 | GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0004435; F:phosphatidylinositol phospholipase C activity; IDA:RGD.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:RGD.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0006661; P:phosphatidylinositol biosynthetic process; ISS:UniProtKB.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0051209; P:release of sequestered calcium ion into cytosol; ISS:UniProtKB.::GO:0033198; P:response to ATP; IDA:RGD.::GO:0032026; P:response to magnesium ion; IDA:RGD. | 153 | Q8TEJ3 | 882 | SH3R3_HUMAN SH3 domain-containing RING finger... | 89 | 3.4 | 34.7 | 24 | 49 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 154 | Q75JD4 | 533 | Y1676_DICDI SH3 and FCH domain-containing pro... | 56 | 0.11 | 39.3 | 32 | 50 | | | | | | | | | | | | | | | | | | | | | | 155 | P20929 | 6669 | NEBU_HUMAN Nebulin OS=Homo sapiens (Human). G... | 51 | 0.12 | 39.3 | 33 | 57 | GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030018; C:Z disc; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0008307; F:structural constituent of muscle; TAS:ProtInc. | | | | | | | | | | GO:0030049; P:muscle filament sliding; TAS:Reactome.::GO:0007517; P:muscle organ development; TAS:ProtInc.::GO:0030832; P:regulation of actin filament length; NAS:UniProtKB.::GO:0007525; P:somatic muscle development; NAS:UniProtKB. | 156 | P16546 | 2472 | SPTA2_MOUSE Spectrin alpha chain, brain OS=Mu... | 77 | 0.13 | 39.3 | 27 | 56 | GO:0032437; C:cuticular plate; IDA:MGI.::GO:0005916; C:fascia adherens; IDA:MGI.::GO:0016328; C:lateral plasma membrane; IDA:MGI.::GO:0033270; C:paranode region of axon; IDA:BHF-UCL.::GO:0030018; C:Z disc; IDA:MGI. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IDA:MGI.::GO:0030507; F:spectrin binding; IDA:MGI. | | | | | | | | | | GO:0051693; P:actin filament capping; IEA:UniProtKB-KW. | 157 | P16086 | 2472 | SPTA2_RAT Spectrin alpha chain, brain OS=Ratt... | 77 | 0.13 | 39.3 | 27 | 56 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.::GO:0008091; C:spectrin; TAS:RGD. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0032403; F:protein complex binding; IPI:RGD.::GO:0047485; F:protein N-terminus binding; IPI:RGD.::GO:0019905; F:syntaxin binding; IPI:RGD. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; IMP:RGD.::GO:0051693; P:actin filament capping; IEA:UniProtKB-KW. | 158 | A4FU49 | 640 | SH321_HUMAN SH3 domain-containing protein 21 ... | 58 | 0.13 | 38.9 | 33 | 52 | | | | | | | | | | | | | | | | | | | | | | 159 | P07751 | 2477 | SPTA2_CHICK Spectrin alpha chain, brain OS=Ga... | 60 | 0.14 | 39.3 | 30 | 60 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051693; P:actin filament capping; IEA:UniProtKB-KW. | 160 | P62484 | 446 | ABI2_MOUSE Abl interactor 2 OS=Mus musculus (... | 60 | 0.15 | 38.5 | 35 | 52 | GO:0005913; C:cell-cell adherens junction; IDA:MGI.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030425; C:dendrite; IDA:MGI.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0043010; P:camera-type eye development; IMP:MGI.::GO:0016477; P:cell migration; IMP:MGI.::GO:0016358; P:dendrite development; IMP:MGI.::GO:0007611; P:learning or memory; IMP:MGI. | 161 | Q13813 | 2472 | SPTA2_HUMAN Spectrin alpha chain, brain OS=Ho... | 60 | 0.15 | 38.9 | 30 | 60 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0015630; C:microtubule cytoskeleton; IDA:HPA.::GO:0008091; C:spectrin; TAS:ProtInc. | | | | | | | | | | GO:0003779; F:actin binding; TAS:ProtInc.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc. | | | | | | | | | | GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome. | 162 | Q9NYB9 | 513 | ABI2_HUMAN Abl interactor 2 OS=Homo sapiens (... | 60 | 0.16 | 38.5 | 35 | 52 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0030175; C:filopodium; IDA:UniProtKB.::GO:0030027; C:lamellipodium; IDA:UniProtKB. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; TAS:UniProtKB.::GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0019900; F:kinase binding; NAS:UniProtKB.::GO:0070064; F:proline-rich region binding; IPI:UniProtKB.::GO:0017124; F:SH3 domain binding; IPI:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL. | | | | | | | | | | GO:0008154; P:actin polymerization or depolymerization; NAS:UniProtKB.::GO:0016477; P:cell migration; TAS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:MGI. | 163 | Q8N157 | 1196 | AHI1_HUMAN Jouberin OS=Homo sapiens (Human). ... | 52 | 0.7 | 37 | 33 | 54 | GO:0005912; C:adherens junction; IDA:UniProtKB.::GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; IDA:UniProtKB.::GO:0036038; C:TCTN-B9D complex; ISS:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0042384; P:cilium assembly; ISS:UniProtKB.::GO:0035844; P:cloaca development; ISS:UniProtKB.::GO:0001947; P:heart looping; ISS:UniProtKB.::GO:0030902; P:hindbrain development; ISS:UniProtKB.::GO:0070121; P:Kupffer's vesicle development; ISS:UniProtKB.::GO:0070986; P:left/right axis specification; ISS:UniProtKB.::GO:0001738; P:morphogenesis of a polarized epithelium; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0071599; P:otic vesicle development; ISS:UniProtKB.::GO:0035845; P:photoreceptor cell outer segment organization; ISS:UniProtKB.::GO:0030862; P:positive regulation of polarized epithelial cell differentiation; ISS:UniProtKB.::GO:0002092; P:positive regulation of receptor internalization; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0039023; P:pronephric duct morphogenesis; ISS:UniProtKB.::GO:0039008; P:pronephric nephron tubule morphogenesis; ISS:UniProtKB.::GO:0050795; P:regulation of behavior; ISS:UniProtKB.::GO:0010842; P:retina layer formation; ISS:UniProtKB.::GO:0065001; P:specification of axis polarity; ISS:UniProtKB.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; ISS:UniProtKB.::GO:0016192; P:vesicle-mediated transport; ISS:UniProtKB. | 164 | Q99962 | 352 | SH3G2_HUMAN Endophilin-A1 OS=Homo sapiens (Hu... | 58 | 0.18 | 38.1 | 31 | 50 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0000139; C:Golgi membrane; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome. | 165 | O88811 | 523 | STAM2_MOUSE Signal transducing adapter molecu... | 64 | 0.39 | 37.4 | 31 | 50 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 166 | Q9Z0R6 | 1659 | ITSN2_MOUSE Intersectin-2 OS=Mus musculus (Mo... | 198 | 2.5 | 35 | 23 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 167 | Q8C120 | 878 | SH3R3_MOUSE SH3 domain-containing RING finger... | 56 | 0.2 | 38.5 | 29 | 55 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 168 | A6QQZ7 | 576 | MPP7_BOVIN MAGUK p55 subfamily member 7 OS=Bo... | 76 | 0.2 | 38.5 | 34 | 50 | GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 169 | A7E8B6 | 1150 | SLA1_SCLS1 Actin cytoskeleton-regulatory comp... | 67 | 3.5 | 34.7 | 31 | 49 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 170 | Q62420 | 352 | SH3G2_MOUSE Endophilin-A1 OS=Mus musculus (Mo... | 58 | 0.21 | 38.1 | 31 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0002090; P:regulation of receptor internalization; IDA:MGI.::GO:0048488; P:synaptic vesicle endocytosis; IGI:MGI. | 171 | Q5T2T1 | 576 | MPP7_HUMAN MAGUK p55 subfamily member 7 OS=Ho... | 76 | 0.21 | 38.1 | 34 | 51 | GO:0097025; C:MPP7-DLG1-LIN7 complex; IDA:BHF-UCL.::GO:0005923; C:tight junction; IDA:BHF-UCL. | | | | | | | | | | GO:0032947; F:protein complex scaffold; IDA:BHF-UCL.::GO:0019904; F:protein domain specific binding; IPI:BHF-UCL.::GO:0046982; F:protein heterodimerization activity; IDA:BHF-UCL.::GO:0035591; F:signaling adaptor activity; NAS:BHF-UCL. | | | | | | | | | | GO:0030010; P:establishment of cell polarity; TAS:BHF-UCL.::GO:0031334; P:positive regulation of protein complex assembly; IDA:BHF-UCL.::GO:0071896; P:protein localization to adherens junction; IMP:BHF-UCL.::GO:0070830; P:tight junction assembly; IDA:BHF-UCL. | 172 | O35179 | 352 | SH3G2_RAT Endophilin-A1 OS=Rattus norvegicus ... | 58 | 0.21 | 38.1 | 31 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | | 173 | Q7SDM3 | 1235 | MYO1_NEUCR Myosin-1 OS=1257 / FGSC 987). GN=m... | 54 | 9 | 33.1 | 26 | 46 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 174 | P27446 | 537 | FYN_XIPHE Tyrosine-protein kinase Fyn OS=Xiph... | 130 | 0.74 | 36.6 | 24 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 175 | Q5U2Y3 | 576 | MPP7_RAT MAGUK p55 subfamily member 7 OS=Ratt... | 76 | 0.22 | 38.1 | 34 | 51 | GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 176 | Q63622 | 852 | DLG2_RAT Disks large homolog 2 OS=Rattus norv... | 39 | 0.22 | 38.5 | 44 | 56 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IDA:RGD.::GO:0044224; C:juxtaparanode region of axon; IDA:MGI.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; TAS:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030165; F:PDZ domain binding; IPI:RGD.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:RGD.::GO:0019903; F:protein phosphatase binding; IPI:BHF-UCL. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.::GO:0045161; P:neuronal ion channel clustering; IMP:RGD.::GO:0043113; P:receptor clustering; IMP:RGD. | 177 | Q15700 | 870 | DLG2_HUMAN Disks large homolog 2 OS=Homo sapi... | 39 | 0.22 | 38.5 | 44 | 56 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; TAS:ProtInc.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004385; F:guanylate kinase activity; TAS:ProtInc. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB. | 178 | O35964 | 368 | SH3G1_RAT Endophilin-A2 OS=Rattus norvegicus ... | 57 | 0.23 | 37.7 | 32 | 53 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005626; C:insoluble fraction; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0051020; F:GTPase binding; IPI:RGD.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0019902; F:phosphatase binding; IPI:RGD. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 179 | Q91XM9 | 852 | DLG2_MOUSE Disks large homolog 2 OS=Mus muscu... | 39 | 0.23 | 38.1 | 44 | 56 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0044224; C:juxtaparanode region of axon; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.::GO:0019233; P:sensory perception of pain; IMP:MGI.::GO:0007268; P:synaptic transmission; IMP:MGI. | 180 | Q62419 | 368 | SH3G1_MOUSE Endophilin-A2 OS=Mus musculus (Mo... | 57 | 0.24 | 37.7 | 32 | 53 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 181 | Q62696 | 911 | DLG1_RAT Disks large homolog 1 OS=Rattus norv... | 42 | 0.24 | 38.1 | 43 | 60 | GO:0009925; C:basal plasma membrane; IDA:RGD.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; TAS:UniProtKB.::GO:0045211; C:postsynaptic membrane; TAS:RGD.::GO:0042734; C:presynaptic membrane; IDA:RGD.::GO:0019717; C:synaptosome; IDA:RGD.::GO:0030315; C:T-tubule; IDA:RGD. | | | | | | | | | | GO:0035255; F:ionotropic glutamate receptor binding; IPI:RGD.::GO:0030165; F:PDZ domain binding; IPI:RGD.::GO:0019902; F:phosphatase binding; ISS:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB. | | | | | | | | | | GO:0007015; P:actin filament organization; ISS:UniProtKB.::GO:0016337; P:cell-cell adhesion; ISS:UniProtKB.::GO:0030866; P:cortical actin cytoskeleton organization; ISS:UniProtKB.::GO:0001935; P:endothelial cell proliferation; ISS:UniProtKB.::GO:0045930; P:negative regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0043268; P:positive regulation of potassium ion transport; IMP:RGD.::GO:0032880; P:regulation of protein localization; IMP:RGD. |
