| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
241 | P46108 | 304 | CRK_HUMAN Adapter molecule crk OS=Homo sapien... | 56 | 1.9 | 34.3 | 32 | 59 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005768; C:endosome; TAS:Reactome.::GO:0005634; C:nucleus; TAS:ProtInc.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB. | | | | | | | | | | GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0048013; P:ephrin receptor signaling pathway; IDA:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0032956; P:regulation of actin cytoskeleton organization; IDA:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; IDA:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc. | 242 | Q64010 | 304 | CRK_MOUSE Adapter molecule crk OS=Mus musculu... | 56 | 2 | 34.3 | 32 | 59 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0045309; F:protein phosphorylated amino acid binding; IDA:MGI.::GO:0005070; F:SH3/SH2 adaptor activity; IPI:BHF-UCL. | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB. | 243 | P97369 | 339 | NCF4_MOUSE Neutrophil cytosol factor 4 OS=Mus... | 54 | 2 | 34.3 | 35 | 56 | GO:0005737; C:cytoplasm; IDA:MGI. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro. | 244 | Q6CHN0 | 1136 | SLA1_YARLI Actin cytoskeleton-regulatory comp... | 56 | 2.1 | 34.7 | 27 | 54 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 245 | Q9XYM0 | 271 | CRK_DROME Adapter molecule Crk OS=Drosophila ... | 37 | 2.3 | 33.9 | 32 | 62 | | | | | | | | | | | GO:0005070; F:SH3/SH2 adaptor activity; IDA:FlyBase. | | | | | | | | | | GO:0007298; P:border follicle cell migration; IMP:FlyBase.::GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0046529; P:imaginal disc fusion, thorax closure; IMP:FlyBase.::GO:0007520; P:myoblast fusion; TAS:FlyBase.::GO:0046330; P:positive regulation of JNK cascade; IDA:FlyBase.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB. | 246 | Q8I1C0 | 369 | SH3G3_DROPS Endophilin-A OS=Drosophila pseudo... | 56 | 2.4 | 34.3 | 30 | 52 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042171; F:lysophosphatidic acid acyltransferase activity; ISS:UniProtKB. | | | | | | | | | | GO:0050803; P:regulation of synapse structure and activity; ISS:UniProtKB.::GO:0048488; P:synaptic vesicle endocytosis; ISS:UniProtKB. | 247 | Q9DC07 | 270 | LNEBL_MOUSE LIM zinc-binding domain-containin... | 55 | 2.6 | 33.9 | 33 | 53 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 248 | Q8I190 | 369 | SH3G3_DROVI Endophilin-A OS=Drosophila virili... | 56 | 2.6 | 33.9 | 30 | 52 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042171; F:lysophosphatidic acid acyltransferase activity; ISS:UniProtKB. | | | | | | | | | | GO:0050803; P:regulation of synapse structure and activity; ISS:UniProtKB.::GO:0048488; P:synaptic vesicle endocytosis; ISS:UniProtKB. | 249 | Q7T2D0 | 755 | SGSM3_DANRE Small G protein signaling modulat... | 57 | 2.8 | 34.3 | 33 | 53 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005097; F:Rab GTPase activator activity; IEA:InterPro. | | | | | | | | | | | 250 | Q13882 | 451 | PTK6_HUMAN Protein-tyrosine kinase 6 OS=Homo ... | 57 | 3.1 | 33.9 | 30 | 56 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0001726; C:ruffle; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0016477; P:cell migration; IDA:UniProtKB.::GO:0071300; P:cellular response to retinoic acid; IMP:BHF-UCL.::GO:0061099; P:negative regulation of protein tyrosine kinase activity; IDA:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IMP:UniProtKB.::GO:0042503; P:tyrosine phosphorylation of Stat3 protein; IDA:UniProtKB.::GO:0042506; P:tyrosine phosphorylation of Stat5 protein; IDA:UniProtKB. | 251 | P13406 | 537 | FYN_XENLA Tyrosine-protein kinase Fyn OS=Xeno... | 53 | 3.2 | 33.9 | 30 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 252 | P05433 | 440 | GAGC_AVISC P47(GAG-CRK) protein OS=Avian sarc... | 57 | 3.2 | 33.9 | 28 | 53 | GO:0019028; C:viral capsid; IEA:InterPro. | | | | | | | | | | GO:0005198; F:structural molecule activity; IEA:InterPro. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW. | 253 | Q8VDG6 | 1002 | M3KL4_MOUSE Mitogen-activated protein kinase ... | 57 | 3.2 | 34.3 | 28 | 53 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | | 254 | Q2KI13 | 747 | SGSM3_BOVIN Small G protein signaling modulat... | 57 | 3.2 | 33.9 | 33 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.::GO:0017137; F:Rab GTPase binding; ISS:UniProtKB. | | | | | | | | | | GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB. | 255 | O15259 | 732 | NPHP1_HUMAN Nephrocystin-1 OS=Homo sapiens (H... | 51 | 3.4 | 33.9 | 31 | 59 | GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0035085; C:cilium axoneme; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.::GO:0031514; C:motile cilium; IDA:UniProtKB.::GO:0032391; C:photoreceptor connecting cilium; ISS:UniProtKB.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005198; F:structural molecule activity; NAS:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; NAS:UniProtKB.::GO:0030030; P:cell projection organization; ISS:UniProtKB.::GO:0016337; P:cell-cell adhesion; NAS:UniProtKB.::GO:0007588; P:excretion; TAS:ProtInc.::GO:0060041; P:retina development in camera-type eye; ISS:UniProtKB.::GO:0007165; P:signal transduction; NAS:UniProtKB.::GO:0048515; P:spermatid differentiation; ISS:UniProtKB.::GO:0007632; P:visual behavior; NAS:UniProtKB. | 256 | O76041 | 1014 | NEBL_HUMAN Nebulette OS=Homo sapiens (Human).... | 55 | 3.5 | 33.9 | 33 | 53 | GO:0001725; C:stress fiber; IDA:UniProtKB.::GO:0030018; C:Z disc; IDA:UniProtKB. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:UniProtKB.::GO:0031005; F:filamin binding; IPI:UniProtKB.::GO:0008307; F:structural constituent of muscle; NAS:UniProtKB.::GO:0005523; F:tropomyosin binding; IPI:UniProtKB. | | | | | | | | | | GO:0071691; P:cardiac muscle thin filament assembly; IMP:UniProtKB. | 257 | Q6P6R7 | 749 | SGSM3_RAT Small G protein signaling modulator... | 57 | 3.5 | 33.9 | 33 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.::GO:0017137; F:Rab GTPase binding; ISS:UniProtKB. | | | | | | | | | | GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB. | 258 | P34092 | 1111 | MYOB_DICDI Myosin IB heavy chain OS=Dictyoste... | 36 | 3.5 | 33.9 | 36 | 61 | GO:0042641; C:actomyosin; IDA:dictyBase.::GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0031252; C:cell leading edge; TAS:dictyBase.::GO:0097203; C:phagocytic cup lip; IDA:dictyBase.::GO:0030670; C:phagocytic vesicle membrane; IDA:dictyBase.::GO:0031143; C:pseudopodium; IEA:UniProtKB-SubCell.::GO:0016461; C:unconventional myosin complex; IDA:dictyBase. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:dictyBase.::GO:0030898; F:actin-dependent ATPase activity; IDA:dictyBase.::GO:0005524; F:ATP binding; IDA:dictyBase.::GO:0000146; F:microfilament motor activity; IDA:dictyBase.::GO:0032031; F:myosin I head/neck binding; IDA:dictyBase. | | | | | | | | | | GO:0033275; P:actin-myosin filament sliding; IDA:dictyBase.::GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0006887; P:exocytosis; IEP:dictyBase.::GO:0006909; P:phagocytosis; IMP:dictyBase.::GO:0051707; P:response to other organism; TAS:dictyBase. | 259 | P27446 | 537 | FYN_XIPHE Tyrosine-protein kinase Fyn OS=Xiph... | 53 | 3.6 | 33.9 | 30 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 260 | Q8VCZ6 | 750 | SGSM3_MOUSE Small G protein signaling modulat... | 57 | 3.6 | 33.9 | 33 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005921; C:gap junction; IDA:UniProtKB. | | | | | | | | | | GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.::GO:0017137; F:Rab GTPase binding; ISS:UniProtKB. | | | | | | | | | | GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0045732; P:positive regulation of protein catabolic process; IDA:UniProtKB.::GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB. | 261 | Q96HU1 | 749 | SGSM3_HUMAN Small G protein signaling modulat... | 57 | 3.7 | 33.9 | 33 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.::GO:0017137; F:Rab GTPase binding; IDA:UniProtKB. | | | | | | | | | | GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0032486; P:Rap protein signal transduction; IEP:UniProtKB. | 262 | P12931 | 536 | SRC_HUMAN Proto-oncogene tyrosine-protein kin... | 53 | 3.8 | 33.9 | 28 | 45 | GO:0005901; C:caveola; IDA:BHF-UCL.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005743; C:mitochondrial inner membrane; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0020037; F:heme binding; IDA:UniProtKB.::GO:0005178; F:integrin binding; TAS:BHF-UCL.::GO:0044325; F:ion channel binding; IPI:BHF-UCL.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:BHF-UCL.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0045453; P:bone resorption; ISS:UniProtKB.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IDA:BHF-UCL.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.::GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway; IMP:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0033625; P:positive regulation of integrin activation; TAS:BHF-UCL.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0045124; P:regulation of bone resorption; TAS:BHF-UCL.::GO:0043114; P:regulation of vascular permeability; TAS:BHF-UCL.::GO:0070555; P:response to interleukin-1; IMP:BHF-UCL.::GO:0007172; P:signal complex assembly; TAS:ProtInc.::GO:0031295; P:T cell costimulation; TAS:Reactome. | 263 | P17713 | 509 | STK_HYDVU Tyrosine-protein kinase STK OS=Hydr... | 77 | 4.5 | 33.5 | 26 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 264 | P13115 | 532 | SRC1_XENLA Tyrosine-protein kinase Src-1 OS=X... | 77 | 5.2 | 33.1 | 26 | 40 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 265 | A6QLK6 | 217 | GRAP_BOVIN GRB2-related adapter protein OS=Bo... | 54 | 5.3 | 32.7 | 33 | 52 | | | | | | | | | | | | | | | | | | | | | | 266 | C0H5F4 | 3179 | RBP2B_PLAF7 Reticulocyte binding protein 2 ho... | 65 | 5.8 | 33.5 | 29 | 52 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016337; P:cell-cell adhesion; ISS:UniProtKB.::GO:0030260; P:entry into host cell; TAS:GeneDB_Pfalciparum. | 267 | Q9CX99 | 217 | GRAP_MOUSE GRB2-related adapter protein OS=Mu... | 55 | 8.5 | 32 | 35 | 53 | | | | | | | | | | | | | | | | | | | | | | 268 | P13116 | 532 | SRC2_XENLA Tyrosine-protein kinase Src-2 OS=X... | 77 | 6.2 | 33.1 | 26 | 40 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 269 | Q02977 | 536 | YRK_CHICK Proto-oncogene tyrosine-protein kin... | 99 | 6.4 | 33.1 | 24 | 41 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 270 | Q04929 | 305 | CRK_CHICK Adapter molecule crk OS=Gallus gall... | 56 | 6.5 | 32.7 | 29 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB. | 271 | A7E8B6 | 1150 | SLA1_SCLS1 Actin cytoskeleton-regulatory comp... | 61 | 6.5 | 33.1 | 28 | 48 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. |
