| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
841 | Q5S007 | 2527 | LRRK2_HUMAN Leucine-rich repeat serine/threon... | 141 | 0.000000001 | 61.2 | 28 | 52 | GO:0032473; C:external side of mitochondrial outer membrane; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0043005; C:neuron projection; IDA:BHF-UCL.::GO:0043025; C:neuronal cell body; IDA:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0034211; F:GTP-dependent protein kinase activity; IMP:UniProtKB.::GO:0005096; F:GTPase activator activity; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:BHF-UCL.::GO:0004708; F:MAP kinase kinase activity; IDA:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0017048; F:Rho GTPase binding; IPI:BHF-UCL.::GO:0015631; F:tubulin binding; IDA:BHF-UCL. | | | | | | | | | | GO:0000186; P:activation of MAPKK activity; IDA:BHF-UCL.::GO:0008340; P:determination of adult lifespan; IMP:BHF-UCL.::GO:0035640; P:exploration behavior; IMP:BHF-UCL.::GO:0048312; P:intracellular distribution of mitochondria; IMP:BHF-UCL.::GO:2000173; P:negative regulation of branching morphogenesis of a nerve; IMP:BHF-UCL.::GO:0061002; P:negative regulation of dendritic spine morphogenesis; IMP:BHF-UCL.::GO:0007406; P:negative regulation of neuroblast proliferation; IMP:BHF-UCL.::GO:0014043; P:negative regulation of neuron maturation; IMP:BHF-UCL.::GO:0007528; P:neuromuscular junction development; IMP:BHF-UCL.::GO:0070997; P:neuron death; IMP:BHF-UCL.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:BHF-UCL.::GO:0010508; P:positive regulation of autophagy; ISS:BHF-UCL.::GO:0060161; P:positive regulation of dopamine receptor signaling pathway; IMP:BHF-UCL.::GO:0043068; P:positive regulation of programmed cell death; IDA:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:BHF-UCL.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:BHF-UCL.::GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0035564; P:regulation of kidney size; ISS:BHF-UCL.::GO:0040012; P:regulation of locomotion; IMP:BHF-UCL.::GO:0042391; P:regulation of membrane potential; IMP:BHF-UCL.::GO:0006979; P:response to oxidative stress; IMP:BHF-UCL.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0022028; P:tangential migration from the subventricular zone to the olfactory bulb; IMP:BHF-UCL. | 842 | Q08E00 | 266 | RASLC_BOVIN Ras-like protein family member 12... | 171 | 0.000000002 | 59.3 | 26 | 48 | GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 843 | Q9GPR2 | 205 | RACI_DICDI Rho-related protein racI OS=Dictyo... | 186 | 0.000000002 | 58.5 | 24 | 46 | GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 844 | Q54FK2 | 184 | RABN2_DICDI Ras-related protein RabN2 OS=Dict... | 183 | 0.000000002 | 57.8 | 27 | 46 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 845 | Q6P0U3 | 244 | RSLBB_DANRE Ras-like protein family member 11... | 208 | 0.000000003 | 58.5 | 26 | 46 | GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 846 | Q23862 | 223 | RACE_DICDI Rho-related protein racE OS=Dictyo... | 190 | 0.000000003 | 58.2 | 25 | 45 | GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0019953; P:sexual reproduction; IEP:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 847 | P34150 | 254 | RACD_DICDI Rho-related protein racD OS=Dictyo... | 160 | 0.000000004 | 58.2 | 28 | 46 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 848 | Q54SD0 | 221 | RABS_DICDI Ras-related protein RabS OS=Dictyo... | 144 | 0.000000005 | 57.8 | 28 | 51 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 849 | P0CO78 | 686 | GEM1_CRYNJ Mitochondrial Rho GTPase 1 OS=ATCC... | 169 | 0.000000007 | 58.5 | 30 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0019725; P:cellular homeostasis; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 850 | P0CO79 | 686 | GEM1_CRYNB Mitochondrial Rho GTPase 1 OS=(Fil... | 169 | 0.000000007 | 58.5 | 30 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0019725; P:cellular homeostasis; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 851 | Q922H7 | 247 | RSLBB_MOUSE Ras-like protein family member 11... | 176 | 0.000000009 | 57.4 | 27 | 45 | GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 852 | Q5S006 | 2527 | LRRK2_MOUSE Leucine-rich repeat serine/threon... | 138 | 0.000000009 | 58.5 | 29 | 53 | GO:0045121; C:membrane raft; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0008021; C:synaptic vesicle; IDA:MGI.::GO:0005802; C:trans-Golgi network; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017048; F:Rho GTPase binding; IPI:BHF-UCL. | | | | | | | | | | GO:0010508; P:positive regulation of autophagy; IMP:BHF-UCL.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:BHF-UCL.::GO:0035564; P:regulation of kidney size; IMP:BHF-UCL.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 853 | P53879 | 331 | RHO5_YEAST GTP-binding protein RHO5 OS=Saccha... | 244 | 0.00000001 | 57.8 | 26 | 44 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005624; C:membrane fraction; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:SGD. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 854 | P52198 | 227 | RND2_HUMAN Rho-related GTP-binding protein Rh... | 141 | 0.00000001 | 56.6 | 25 | 49 | GO:0002080; C:acrosomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 855 | Q9QYM5 | 227 | RND2_MOUSE Rho-related GTP-binding protein Rh... | 141 | 0.00000001 | 56.6 | 25 | 49 | GO:0002080; C:acrosomal membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:MGI. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 856 | Q6IMA7 | 247 | RSLBB_RAT Ras-like protein family member 11B ... | 176 | 0.00000001 | 56.6 | 26 | 45 | GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 857 | P52498 | 248 | RSR1_CANAX Ras-related protein RSR1 OS=Candid... | 168 | 0.00000001 | 56.6 | 29 | 51 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 858 | Q864R5 | 620 | MIRO2_PIG Mitochondrial Rho GTPase 2 OS=Sus s... | 179 | 0.00000001 | 57.8 | 30 | 42 | GO:0031307; C:integral to mitochondrial outer membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0019725; P:cellular homeostasis; ISS:UniProtKB.::GO:0047497; P:mitochondrion transport along microtubule; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 859 | Q9BPW5 | 248 | RSLBB_HUMAN Ras-like protein family member 11... | 176 | 0.00000002 | 56.6 | 30 | 46 | GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 860 | Q92730 | 232 | RND1_HUMAN Rho-related GTP-binding protein Rh... | 129 | 0.00000002 | 55.8 | 25 | 49 | GO:0005912; C:adherens junction; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; NAS:UniProtKB.::GO:0005102; F:receptor binding; IPI:UniProtKB. | | | | | | | | | | GO:0007015; P:actin filament organization; IDA:UniProtKB.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007162; P:negative regulation of cell adhesion; IDA:UniProtKB.::GO:0016322; P:neuron remodeling; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 861 | Q8BLR7 | 232 | RND1_MOUSE Rho-related GTP-binding protein Rh... | 128 | 0.00000002 | 55.8 | 25 | 49 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 862 | Q7SZ59 | 255 | RASLC_DANRE Ras-like protein family member 12... | 160 | 0.00000003 | 55.8 | 27 | 48 | GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 863 | Q32NS2 | 163 | KBRS2_XENLA NF-kappa-B inhibitor-interacting ... | 153 | 0.00000003 | 54.3 | 27 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 864 | Q2HJ68 | 232 | RND1_BOVIN Rho-related GTP-binding protein Rh... | 129 | 0.00000004 | 55.1 | 25 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 865 | Q5E9J3 | 248 | RSLBB_BOVIN Ras-like protein family member 11... | 170 | 0.00000004 | 55.5 | 28 | 46 | GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 866 | Q9NYS0 | 192 | KBRS1_HUMAN NF-kappa-B inhibitor-interacting ... | 149 | 0.00000005 | 54.3 | 30 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; NAS:UniProtKB. | | | | | | | | | | GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; NAS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 867 | Q9BH04 | 192 | KBRS1_MACFA NF-kappa-B inhibitor-interacting ... | 149 | 0.00000005 | 54.3 | 30 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 868 | Q4PB75 | 752 | GEM1_USTMA Mitochondrial Rho GTPase 1 OS=Usti... | 172 | 0.00000006 | 55.8 | 27 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 869 | Q8CEC5 | 192 | KBRS1_MOUSE NF-kappa-B inhibitor-interacting ... | 139 | 0.00000009 | 53.5 | 31 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 870 | Q9NYN1 | 266 | RASLC_HUMAN Ras-like protein family member 12... | 171 | 0.0000002 | 53.5 | 26 | 49 | GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 871 | Q32LU1 | 617 | MIRO2_DANRE Mitochondrial Rho GTPase 2 OS=Dan... | 179 | 0.0000002 | 53.9 | 29 | 45 | GO:0031307; C:integral to mitochondrial outer membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0019725; P:cellular homeostasis; ISS:UniProtKB.::GO:0047497; P:mitochondrion transport along microtubule; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. |
