| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q12324 | 675 | YVC1_YEAST Calcium channel YVC1 OS=Saccharomy... | 540 | 2e-132 | 412 | 41 | 62 | GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005227; F:calcium activated cation channel activity; IDA:SGD.::GO:0005262; F:calcium channel activity; IDA:SGD.::GO:0005267; F:potassium channel activity; IDA:SGD.::GO:0005272; F:sodium channel activity; IDA:SGD.::GO:0005244; F:voltage-gated ion channel activity; IDA:SGD. | | | | | | | | | | GO:0030003; P:cellular cation homeostasis; IDA:SGD. | 2 | Q9QUQ5 | 974 | TRPC4_MOUSE Short transient receptor potentia... | 274 | 0.0000000005 | 66.2 | 25 | 46 | GO:0005901; C:caveola; IDA:MGI.::GO:0045121; C:membrane raft; IDA:MGI. | | | | | | | | | | GO:0070679; F:inositol 1,4,5 trisphosphate binding; IDA:BHF-UCL.::GO:0015279; F:store-operated calcium channel activity; IMP:MGI. | | | | | | | | | | GO:0014051; P:gamma-aminobutyric acid secretion; IMP:MGI. | 3 | O35119 | 977 | TRPC4_RAT Short transient receptor potential ... | 274 | 0.0000000006 | 66.2 | 25 | 46 | GO:0005887; C:integral to plasma membrane; IDA:RGD. | | | | | | | | | | | | | | | | | | | | GO:0051924; P:regulation of calcium ion transport; IMP:RGD. | 4 | P79100 | 979 | TRPC4_BOVIN Short transient receptor potentia... | 274 | 0.0000000006 | 66.2 | 25 | 46 | | | | | | | | | | | | | | | | | | | | | | 5 | Q9UBN4 | 977 | TRPC4_HUMAN Short transient receptor potentia... | 274 | 0.000000001 | 65.1 | 25 | 46 | GO:0016323; C:basolateral plasma membrane; IDA:BHF-UCL.::GO:0034704; C:calcium channel complex; IDA:UniProtKB.::GO:0009986; C:cell surface; IDA:BHF-UCL.::GO:0030863; C:cortical cytoskeleton; IDA:UniProtKB. | | | | | | | | | | GO:0008013; F:beta-catenin binding; IPI:BHF-UCL.::GO:0045296; F:cadherin binding; IPI:BHF-UCL.::GO:0015279; F:store-operated calcium channel activity; IMP:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0070509; P:calcium ion import; IDA:BHF-UCL. | 6 | Q9WVC5 | 862 | TRPC7_MOUSE Short transient receptor potentia... | 340 | 0.00000006 | 59.7 | 22 | 41 | GO:0016021; C:integral to membrane; IC:MGI.::GO:0005635; C:nuclear envelope; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005262; F:calcium channel activity; IDA:MGI. | | | | | | | | | | GO:0006828; P:manganese ion transport; IDA:MGI. | 7 | Q9HCX4 | 862 | TRPC7_HUMAN Short transient receptor potentia... | 340 | 0.00000008 | 59.3 | 22 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005635; C:nuclear envelope; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome. | 8 | Q13507 | 836 | TRPC3_HUMAN Short transient receptor potentia... | 279 | 0.0000001 | 58.5 | 23 | 41 | GO:0005887; C:integral to plasma membrane; IDA:MGI. | | | | | | | | | | GO:0070679; F:inositol 1,4,5 trisphosphate binding; IDA:BHF-UCL.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0015279; F:store-operated calcium channel activity; TAS:ProtInc. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007602; P:phototransduction; TAS:ProtInc.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0010524; P:positive regulation of calcium ion transport into cytosol; IDA:UniProtKB.::GO:0033198; P:response to ATP; IDA:UniProtKB.::GO:0051592; P:response to calcium ion; IDA:UniProtKB. | 9 | Q9QX29 | 975 | TRPC5_MOUSE Short transient receptor potentia... | 266 | 0.0000002 | 58.5 | 23 | 44 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW.::GO:0070679; F:inositol 1,4,5 trisphosphate binding; IDA:BHF-UCL.::GO:0005515; F:protein binding; IPI:BHF-UCL. | | | | | | | | | | | 10 | O62852 | 974 | TRPC5_RABIT Short transient receptor potentia... | 266 | 0.0000002 | 58.2 | 23 | 44 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW. | | | | | | | | | | | 11 | Q9UL62 | 973 | TRPC5_HUMAN Short transient receptor potentia... | 266 | 0.0000003 | 57.8 | 23 | 44 | GO:0034704; C:calcium channel complex; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0015279; F:store-operated calcium channel activity; TAS:ProtInc. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome. | 12 | Q9JMI9 | 836 | TRPC3_RAT Short transient receptor potential ... | 279 | 0.0000005 | 56.6 | 23 | 41 | | | | | | | | | | | GO:0005227; F:calcium activated cation channel activity; IDA:RGD.::GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW. | | | | | | | | | | | 13 | Q9QZC1 | 836 | TRPC3_MOUSE Short transient receptor potentia... | 279 | 0.0000006 | 56.6 | 23 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW. | | | | | | | | | | | 14 | Q61143 | 930 | TRPC6_MOUSE Short transient receptor potentia... | 276 | 0.000001 | 55.5 | 22 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0036057; C:slit diaphragm; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0015279; F:store-operated calcium channel activity; IDA:MGI. | | | | | | | | | | GO:0007204; P:elevation of cytosolic calcium ion concentration; IDA:MGI. | 15 | Q9Y210 | 931 | TRPC6_HUMAN Short transient receptor potentia... | 276 | 0.000002 | 55.1 | 22 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0070679; F:inositol 1,4,5 trisphosphate binding; IDA:BHF-UCL.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0032236; P:positive regulation of calcium ion transport via store-operated calcium channel activity; IDA:MGI. | 16 | Q9R283 | 1170 | TRPC2_RAT Short transient receptor potential ... | 256 | 0.000002 | 54.7 | 26 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003684; F:damaged DNA binding; IEA:InterPro. | | | | | | | | | | GO:0000012; P:single strand break repair; IEA:InterPro. | 17 | Q9R244 | 1172 | TRPC2_MOUSE Short transient receptor potentia... | 255 | 0.00001 | 52.8 | 25 | 44 | GO:0032590; C:dendrite membrane; IMP:MGI.::GO:0005789; C:endoplasmic reticulum membrane; IDA:MGI.::GO:0000139; C:Golgi membrane; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005635; C:nuclear envelope; IDA:MGI.::GO:0005634; C:nucleus; IEA:InterPro. | | | | | | | | | | GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IDA:MGI.::GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0019992; F:diacylglycerol binding; IMP:MGI.::GO:0070679; F:inositol 1,4,5 trisphosphate binding; IDA:BHF-UCL.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0015279; F:store-operated calcium channel activity; IDA:MGI. | | | | | | | | | | GO:0007340; P:acrosome reaction; IMP:MGI.::GO:0007204; P:elevation of cytosolic calcium ion concentration; IPI:MGI.::GO:0008050; P:female courtship behavior; IMP:MGI.::GO:0002121; P:inter-male aggressive behavior; IMP:MGI.::GO:0048047; P:mating behavior, sex discrimination; IMP:MGI.::GO:0019236; P:response to pheromone; IMP:MGI.::GO:0000012; P:single strand break repair; IEA:InterPro.::GO:0002124; P:territorial aggressive behavior; IMP:MGI. | 18 | Q9VJJ7 | 1128 | TRPG_DROME Transient receptor potential-gamma... | 334 | 0.00002 | 51.6 | 20 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0016028; C:rhabdomere; IDA:UniProtKB. | | | | | | | | | | GO:0005262; F:calcium channel activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0050908; P:detection of light stimulus involved in visual perception; ISS:UniProtKB. | 19 | O62826 | 432 | TRPC2_BOVIN Short transient receptor potentia... | 201 | 0.0001 | 48.5 | 26 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW. | | | | | | | | | | | 20 | A8DYE2 | 2023 | TRPCG_DROME Transient receptor potential cati... | 187 | 0.007 | 43.5 | 20 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005216; F:ion channel activity; IEA:UniProtKB-KW.::GO:0046873; F:metal ion transmembrane transporter activity; IDA:FlyBase. | | | | | | | | | | GO:0016049; P:cell growth; IMP:FlyBase.::GO:0070838; P:divalent metal ion transport; IDA:FlyBase.::GO:0010960; P:magnesium ion homeostasis; IMP:FlyBase.::GO:0007005; P:mitochondrion organization; IMP:FlyBase.::GO:0055069; P:zinc ion homeostasis; IMP:FlyBase. | 21 | P48994 | 1124 | TRPL_DROME Transient-receptor-potential-like ... | 281 | 0.007 | 43.1 | 18 | 44 | GO:0016027; C:inaD signaling complex; IPI:UniProtKB.::GO:0016021; C:integral to membrane; NAS:UniProtKB.::GO:0005622; C:intracellular; IDA:UniProtKB. | | | | | | | | | | GO:0005516; F:calmodulin binding; IDA:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0015279; F:store-operated calcium channel activity; NAS:FlyBase. | | | | | | | | | | GO:0007589; P:body fluid secretion; IMP:FlyBase.::GO:0019722; P:calcium-mediated signaling; IMP:FlyBase.::GO:0071454; P:cellular response to anoxia; IGI:FlyBase.::GO:0050908; P:detection of light stimulus involved in visual perception; ISS:UniProtKB. | 22 | P19334 | 1275 | TRP_DROME Transient receptor potential protei... | 77 | 0.029 | 41.6 | 29 | 56 | GO:0016027; C:inaD signaling complex; IPI:UniProtKB.::GO:0016021; C:integral to membrane; NAS:UniProtKB. | | | | | | | | | | GO:0005516; F:calmodulin binding; TAS:FlyBase.::GO:0005218; F:intracellular ligand-gated calcium channel activity; NAS:FlyBase.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0015279; F:store-operated calcium channel activity; NAS:FlyBase. | | | | | | | | | | GO:0019722; P:calcium-mediated signaling; TAS:FlyBase.::GO:0071454; P:cellular response to anoxia; IGI:FlyBase.::GO:0030845; P:inhibition of phospholipase C activity involved in G-protein coupled receptor signaling pathway; IMP:FlyBase.::GO:0008377; P:light-induced release of internally sequestered calcium ion; IDA:FlyBase.::GO:0008355; P:olfactory learning; IMP:UniProtKB.::GO:0008104; P:protein localization; IMP:UniProtKB.::GO:0007608; P:sensory perception of smell; IEA:UniProtKB-KW. | 23 | O75762 | 1119 | TRPA1_HUMAN Transient receptor potential cati... | 127 | 0.11 | 39.7 | 26 | 43 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | | | | | | | | | | | | 24 | Q7Z020 | 1296 | TRPA1_DROME Transient receptor potential cati... | 239 | 0.12 | 39.7 | 24 | 43 | GO:0016021; C:integral to membrane; IC:UniProtKB. | | | | | | | | | | GO:0005261; F:cation channel activity; IDA:UniProtKB. | | | | | | | | | | GO:0034605; P:cellular response to heat; IDA:FlyBase.::GO:0042745; P:circadian sleep/wake cycle; IMP:FlyBase.::GO:0001580; P:detection of chemical stimulus involved in sensory perception of bitter taste; IMP:FlyBase.::GO:0007613; P:memory; IMP:FlyBase.::GO:0043052; P:thermotaxis; IDA:FlyBase. | 25 | Q6RI86 | 1125 | TRPA1_RAT Transient receptor potential cation... | 129 | 0.21 | 38.5 | 26 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 26 | Q8BLA8 | 1125 | TRPA1_MOUSE Transient receptor potential cati... | 129 | 0.22 | 38.5 | 26 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0032421; C:stereocilium bundle; IDA:MGI. | | | | | | | | | | GO:0005262; F:calcium channel activity; IDA:MGI. | | | | | | | | | | GO:0050968; P:detection of chemical stimulus involved in sensory perception of pain; IDA:MGI.::GO:0050966; P:detection of mechanical stimulus involved in sensory perception of pain; IMP:MGI.::GO:0009409; P:response to cold; IDA:MGI.::GO:0042493; P:response to drug; IDA:MGI.::GO:0042542; P:response to hydrogen peroxide; IMP:MGI.::GO:0048265; P:response to pain; IDA:MGI.::GO:0050955; P:thermoception; IDA:MGI. | 27 | Q9U1S7 | 716 | PKD2_CAEEL Polycystin-2 OS=Caenorhabditis ele... | 216 | 0.31 | 38.1 | 23 | 38 | GO:0030424; C:axon; IDA:WormBase.::GO:0060170; C:cilium membrane; IDA:UniProtKB.::GO:0030425; C:dendrite; IDA:WormBase.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031513; C:nonmotile primary cilium; IDA:WormBase.::GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005262; F:calcium channel activity; IDA:UniProtKB.::GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0034606; P:response to hermaphrodite contact; IMP:UniProtKB.::GO:0034608; P:vulval location; IMP:UniProtKB. | 28 | Q18297 | 1211 | TRPA1_CAEEL Transient receptor potential cati... | 150 | 0.49 | 37.4 | 22 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005216; F:ion channel activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW. | 29 | Q5R7G6 | 523 | PEPL1_PONAB Probable aminopeptidase NPEPL1 OS... | 84 | 0.75 | 36.6 | 29 | 46 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0008235; F:metalloexopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 30 | Q8NDH3 | 523 | PEPL1_HUMAN Probable aminopeptidase NPEPL1 OS... | 84 | 0.75 | 36.6 | 29 | 46 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0008235; F:metalloexopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 31 | Q9JIP0 | 723 | TRPV5_RAT Transient receptor potential cation... | 130 | 2.4 | 35 | 26 | 44 | GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005262; F:calcium channel activity; ISS:UniProtKB.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051262; P:protein tetramerization; ISS:UniProtKB. |
