| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q5GRG2 | 575 | EST5A_RAT Carboxylesterase 5A OS=Rattus norve... | 469 | 2e-41 | 162 | 30 | 48 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004091; F:carboxylesterase activity; IBA:RefGenome.::GO:0080030; F:methyl indole-3-acetate esterase activity; IEA:EC.::GO:0080032; F:methyl jasmonate esterase activity; IEA:EC.::GO:0080031; F:methyl salicylate esterase activity; IEA:EC.::GO:0050253; F:retinyl-palmitate esterase activity; IEA:EC. | | | | | | | | | | | 2 | P37967 | 489 | PNBA_BACSU Para-nitrobenzyl esterase OS=Bacil... | 531 | 2e-41 | 160 | 28 | 45 | | | | | | | | | | | GO:0004091; F:carboxylesterase activity; IBA:RefGenome.::GO:0004104; F:cholinesterase activity; IEA:InterPro. | | | | | | | | | | | 3 | Q8N0W4 | 816 | NLGNX_HUMAN Neuroligin-4, X-linked OS=Homo sa... | 549 | 3e-41 | 164 | 27 | 44 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0060076; C:excitatory synapse; IDA:BHF-UCL.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0031404; F:chloride ion binding; IDA:UniProtKB.::GO:0042043; F:neurexin family protein binding; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0004872; F:receptor activity; IBA:RefGenome. | | | | | | | | | | GO:0003360; P:brainstem development; ISS:BHF-UCL.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0045216; P:cell-cell junction organization; NAS:UniProtKB.::GO:0021549; P:cerebellum development; ISS:BHF-UCL.::GO:0090394; P:negative regulation of excitatory postsynaptic membrane potential; IDA:BHF-UCL.::GO:0046622; P:positive regulation of organ growth; ISS:BHF-UCL.::GO:0097105; P:presynaptic membrane assembly; IDA:BHF-UCL.::GO:0035176; P:social behavior; IMP:UniProtKB.::GO:0071625; P:vocalization behavior; IMP:BHF-UCL. | 4 | Q8NFZ3 | 816 | NLGNY_HUMAN Neuroligin-4, Y-linked OS=Homo sa... | 547 | 7e-41 | 163 | 27 | 44 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0009986; C:cell surface; IBA:RefGenome.::GO:0005887; C:integral to plasma membrane; IBA:RefGenome.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042043; F:neurexin family protein binding; IBA:RefGenome.::GO:0004872; F:receptor activity; IBA:RefGenome. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007416; P:synapse assembly; IBA:RefGenome. | 5 | Q8BYM5 | 825 | NLGN3_MOUSE Neuroligin-3 OS=Mus musculus (Mou... | 552 | 3e-40 | 161 | 27 | 43 | GO:0009986; C:cell surface; ISS:BHF-UCL.::GO:0030139; C:endocytic vesicle; ISS:BHF-UCL.::GO:0060076; C:excitatory synapse; ISS:BHF-UCL.::GO:0005887; C:integral to plasma membrane; ISS:BHF-UCL. | | | | | | | | | | GO:0050839; F:cell adhesion molecule binding; ISS:BHF-UCL.::GO:0042043; F:neurexin family protein binding; IBA:RefGenome.::GO:0004872; F:receptor activity; IBA:RefGenome. | | | | | | | | | | GO:0048675; P:axon extension; ISS:BHF-UCL.::GO:0007158; P:neuron cell-cell adhesion; ISS:BHF-UCL.::GO:2000969; P:positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; IMP:BHF-UCL.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; IMP:BHF-UCL.::GO:0051965; P:positive regulation of synapse assembly; ISS:BHF-UCL.::GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; IMP:BHF-UCL.::GO:0097104; P:postsynaptic membrane assembly; IMP:BHF-UCL.::GO:0097105; P:presynaptic membrane assembly; ISS:BHF-UCL.::GO:0006898; P:receptor-mediated endocytosis; ISS:BHF-UCL.::GO:0060080; P:regulation of inhibitory postsynaptic membrane potential; IMP:MGI.::GO:0060024; P:rhythmic synaptic transmission; ISS:BHF-UCL.::GO:0035176; P:social behavior; IMP:MGI.::GO:0008542; P:visual learning; IMP:MGI. | 6 | Q6AW46 | 575 | EST5A_MOUSE Carboxylesterase 5A OS=Mus muscul... | 497 | 3e-39 | 155 | 29 | 45 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004091; F:carboxylesterase activity; IBA:RefGenome.::GO:0080030; F:methyl indole-3-acetate esterase activity; IEA:EC.::GO:0080032; F:methyl jasmonate esterase activity; IEA:EC.::GO:0080031; F:methyl salicylate esterase activity; IEA:EC.::GO:0050253; F:retinyl-palmitate esterase activity; IEA:EC. | | | | | | | | | | | 7 | Q6NT32 | 575 | EST5A_HUMAN Carboxylesterase 5A OS=Homo sapie... | 493 | 4e-39 | 155 | 29 | 46 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004091; F:carboxylesterase activity; IBA:RefGenome.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0080030; F:methyl indole-3-acetate esterase activity; IEA:EC.::GO:0080032; F:methyl jasmonate esterase activity; IEA:EC.::GO:0080031; F:methyl salicylate esterase activity; IEA:EC.::GO:0050253; F:retinyl-palmitate esterase activity; IEA:EC. | | | | | | | | | | | 8 | Q99K10 | 843 | NLGN1_MOUSE Neuroligin-1 OS=Mus musculus (Mou... | 536 | 3e-38 | 155 | 27 | 43 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0009986; C:cell surface; ISS:BHF-UCL.::GO:0060076; C:excitatory synapse; IC:BHF-UCL.::GO:0005887; C:integral to plasma membrane; IMP:UniProtKB.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042043; F:neurexin family protein binding; IMP:UniProtKB.::GO:0046983; F:protein dimerization activity; ISS:BHF-UCL.::GO:0004872; F:receptor activity; IBA:RefGenome. | | | | | | | | | | GO:0097113; P:alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering; IDA:BHF-UCL.::GO:0016339; P:calcium-dependent cell-cell adhesion; ISS:UniProtKB.::GO:0048789; P:cytoskeletal matrix organization at active zone; IMP:BHF-UCL.::GO:0007157; P:heterophilic cell-cell adhesion; IDA:BHF-UCL.::GO:0097115; P:neurexin clustering; IDA:BHF-UCL.::GO:0007158; P:neuron cell-cell adhesion; IDA:BHF-UCL.::GO:0060999; P:positive regulation of dendritic spine development; ISS:BHF-UCL.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; IDA:BHF-UCL.::GO:0051965; P:positive regulation of synapse assembly; ISS:BHF-UCL.::GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; ISS:BHF-UCL.::GO:1900244; P:positive regulation of synaptic vesicle endocytosis; IMP:BHF-UCL.::GO:2000302; P:positive regulation of synaptic vesicle exocytosis; IMP:BHF-UCL.::GO:0097119; P:postsynaptic density protein 95 clustering; IDA:BHF-UCL.::GO:0097104; P:postsynaptic membrane assembly; IDA:BHF-UCL.::GO:0097105; P:presynaptic membrane assembly; IDA:BHF-UCL.::GO:0051260; P:protein homooligomerization; IDA:BHF-UCL.::GO:0097120; P:receptor localization to synapse; IDA:BHF-UCL.::GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:BHF-UCL.::GO:2000310; P:regulation of N-methyl-D-aspartate selective glutamate receptor activity; IDA:BHF-UCL.::GO:0002087; P:regulation of respiratory gaseous exchange by neurological system process; IGI:MGI.::GO:0097091; P:synaptic vesicle clustering; IDA:BHF-UCL.::GO:0016080; P:synaptic vesicle targeting; IMP:UniProtKB.::GO:0072553; P:terminal button organization; IMP:BHF-UCL. | 9 | Q8N2Q7 | 840 | NLGN1_HUMAN Neuroligin-1 OS=Homo sapiens (Hum... | 560 | 3e-38 | 155 | 27 | 43 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0009986; C:cell surface; ISS:BHF-UCL.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.::GO:0014069; C:postsynaptic density; TAS:BHF-UCL.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050839; F:cell adhesion molecule binding; ISS:BHF-UCL.::GO:0042043; F:neurexin family protein binding; ISS:UniProtKB.::GO:0046983; F:protein dimerization activity; ISS:BHF-UCL.::GO:0004872; F:receptor activity; ISS:BHF-UCL. | | | | | | | | | | GO:0097113; P:alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering; ISS:BHF-UCL.::GO:0016339; P:calcium-dependent cell-cell adhesion; ISS:UniProtKB.::GO:0048789; P:cytoskeletal matrix organization at active zone; ISS:BHF-UCL.::GO:0007157; P:heterophilic cell-cell adhesion; ISS:BHF-UCL.::GO:0097115; P:neurexin clustering; ISS:BHF-UCL.::GO:0007158; P:neuron cell-cell adhesion; ISS:BHF-UCL.::GO:0023041; P:neuronal signal transduction; TAS:BHF-UCL.::GO:0060999; P:positive regulation of dendritic spine development; ISS:BHF-UCL.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.::GO:0051491; P:positive regulation of filopodium assembly; ISS:BHF-UCL.::GO:0010740; P:positive regulation of intracellular protein kinase cascade; ISS:BHF-UCL.::GO:1900029; P:positive regulation of ruffle assembly; ISS:BHF-UCL.::GO:0051965; P:positive regulation of synapse assembly; ISS:BHF-UCL.::GO:0032230; P:positive regulation of synaptic transmission, GABAergic; ISS:BHF-UCL.::GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; ISS:BHF-UCL.::GO:1900244; P:positive regulation of synaptic vesicle endocytosis; ISS:BHF-UCL.::GO:2000302; P:positive regulation of synaptic vesicle exocytosis; ISS:BHF-UCL.::GO:0097119; P:postsynaptic density protein 95 clustering; ISS:BHF-UCL.::GO:0097104; P:postsynaptic membrane assembly; ISS:BHF-UCL.::GO:0097105; P:presynaptic membrane assembly; ISS:BHF-UCL.::GO:0051260; P:protein homooligomerization; ISS:BHF-UCL.::GO:0006605; P:protein targeting; ISS:UniProtKB.::GO:0097120; P:receptor localization to synapse; ISS:BHF-UCL.::GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:BHF-UCL.::GO:2000310; P:regulation of N-methyl-D-aspartate selective glutamate receptor activity; ISS:BHF-UCL.::GO:0097091; P:synaptic vesicle clustering; ISS:BHF-UCL.::GO:0016080; P:synaptic vesicle targeting; ISS:UniProtKB.::GO:0072553; P:terminal button organization; ISS:BHF-UCL. | 10 | P22303 | 614 | ACES_HUMAN Acetylcholinesterase OS=Homo sapie... | 505 | 5e-38 | 152 | 27 | 44 | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0030424; C:axon; IBA:RefGenome.::GO:0005605; C:basal lamina; NAS:HGNC.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0009986; C:cell surface; IBA:RefGenome.::GO:0030425; C:dendrite; IBA:RefGenome.::GO:0005788; C:endoplasmic reticulum lumen; IBA:RefGenome.::GO:0005615; C:extracellular space; IBA:RefGenome.::GO:0005794; C:Golgi apparatus; IDA:HGNC.::GO:0031594; C:neuromuscular junction; IBA:RefGenome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IDA:HGNC.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0045211; C:postsynaptic membrane; IBA:RefGenome.::GO:0042734; C:presynaptic membrane; IBA:RefGenome.::GO:0043083; C:synaptic cleft; NAS:GOC. | | | | | | | | | | GO:0042166; F:acetylcholine binding; NAS:UniProtKB.::GO:0003990; F:acetylcholinesterase activity; IMP:UniProtKB.::GO:0001540; F:beta-amyloid binding; TAS:UniProtKB.::GO:0004091; F:carboxylesterase activity; IBA:RefGenome.::GO:0005518; F:collagen binding; IDA:HGNC.::GO:0043236; F:laminin binding; IDA:BHF-UCL.::GO:0042803; F:protein homodimerization activity; NAS:UniProtKB.::GO:0017171; F:serine hydrolase activity; IDA:HGNC. | | | | | | | | | | GO:0001507; P:acetylcholine catabolic process in synaptic cleft; NAS:UniProtKB.::GO:0042982; P:amyloid precursor protein metabolic process; TAS:UniProtKB.::GO:0007155; P:cell adhesion; TAS:UniProtKB.::GO:0008283; P:cell proliferation; TAS:UniProtKB.::GO:0019695; P:choline metabolic process; IBA:RefGenome.::GO:0006260; P:DNA replication; TAS:UniProtKB.::GO:0007517; P:muscle organ development; TAS:UniProtKB.::GO:0032223; P:negative regulation of synaptic transmission, cholinergic; IC:HGNC.::GO:0042136; P:neurotransmitter biosynthetic process; TAS:Reactome.::GO:0002076; P:osteoblast development; IEP:HGNC.::GO:0050714; P:positive regulation of protein secretion; TAS:UniProtKB.::GO:0050770; P:regulation of axonogenesis; IBA:RefGenome.::GO:0048814; P:regulation of dendrite morphogenesis; IBA:RefGenome.::GO:0009611; P:response to wounding; TAS:UniProtKB.::GO:0007416; P:synapse assembly; TAS:UniProtKB. | 11 | Q6AW47 | 575 | EST5A_CANFA Carboxylesterase 5A OS=Canis fami... | 495 | 6e-38 | 152 | 28 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004091; F:carboxylesterase activity; IBA:RefGenome.::GO:0080030; F:methyl indole-3-acetate esterase activity; IEA:EC.::GO:0080032; F:methyl jasmonate esterase activity; IEA:EC.::GO:0080031; F:methyl salicylate esterase activity; IEA:EC.::GO:0050253; F:retinyl-palmitate esterase activity; IEA:EC. | | | | | | | | | | | 12 | Q62889 | 848 | NLGN3_RAT Neuroligin-3 OS=Rattus norvegicus (... | 572 | 1e-37 | 153 | 26 | 41 | GO:0009986; C:cell surface; IDA:BHF-UCL.::GO:0030139; C:endocytic vesicle; IDA:BHF-UCL.::GO:0060076; C:excitatory synapse; IDA:BHF-UCL.::GO:0060077; C:inhibitory synapse; IC:BHF-UCL.::GO:0005887; C:integral to plasma membrane; IDA:BHF-UCL. | | | | | | | | | | GO:0050839; F:cell adhesion molecule binding; IPI:BHF-UCL.::GO:0042043; F:neurexin family protein binding; IPI:BHF-UCL.::GO:0004872; F:receptor activity; IDA:BHF-UCL. | | | | | | | | | | GO:0048675; P:axon extension; IMP:BHF-UCL.::GO:0007158; P:neuron cell-cell adhesion; IDA:BHF-UCL.::GO:2000969; P:positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:BHF-UCL.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.::GO:0051965; P:positive regulation of synapse assembly; IDA:BHF-UCL.::GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; ISS:BHF-UCL.::GO:0097104; P:postsynaptic membrane assembly; ISS:BHF-UCL.::GO:0097105; P:presynaptic membrane assembly; IDA:BHF-UCL.::GO:0006898; P:receptor-mediated endocytosis; IDA:BHF-UCL.::GO:0060080; P:regulation of inhibitory postsynaptic membrane potential; IDA:BHF-UCL.::GO:0060024; P:rhythmic synaptic transmission; IMP:BHF-UCL. | 13 | Q9NZ94 | 848 | NLGN3_HUMAN Neuroligin-3 OS=Homo sapiens (Hum... | 572 | 1e-37 | 153 | 26 | 41 | GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0030139; C:endocytic vesicle; ISS:BHF-UCL.::GO:0060076; C:excitatory synapse; IDA:BHF-UCL.::GO:0005887; C:integral to plasma membrane; ISS:BHF-UCL. | | | | | | | | | | GO:0050839; F:cell adhesion molecule binding; ISS:BHF-UCL.::GO:0042043; F:neurexin family protein binding; ISS:BHF-UCL.::GO:0004872; F:receptor activity; ISS:BHF-UCL. | | | | | | | | | | GO:0048675; P:axon extension; ISS:BHF-UCL.::GO:0007158; P:neuron cell-cell adhesion; ISS:BHF-UCL.::GO:2000969; P:positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:BHF-UCL.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.::GO:0051965; P:positive regulation of synapse assembly; ISS:BHF-UCL.::GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; ISS:BHF-UCL.::GO:0097104; P:postsynaptic membrane assembly; ISS:BHF-UCL.::GO:0097105; P:presynaptic membrane assembly; ISS:BHF-UCL.::GO:0006898; P:receptor-mediated endocytosis; ISS:BHF-UCL.::GO:0060080; P:regulation of inhibitory postsynaptic membrane potential; ISS:BHF-UCL.::GO:0060024; P:rhythmic synaptic transmission; ISS:BHF-UCL.::GO:0035176; P:social behavior; IMP:UniProtKB. | 14 | Q29550 | 566 | EST1_PIG Liver carboxylesterase OS=Sus scrofa... | 539 | 2e-37 | 150 | 29 | 44 | GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004091; F:carboxylesterase activity; IEA:UniProtKB-KW.::GO:0080030; F:methyl indole-3-acetate esterase activity; IEA:EC.::GO:0080032; F:methyl jasmonate esterase activity; IEA:EC.::GO:0080031; F:methyl salicylate esterase activity; IEA:EC.::GO:0050253; F:retinyl-palmitate esterase activity; IEA:EC. | | | | | | | | | | | 15 | P37136 | 614 | ACES_RAT Acetylcholinesterase OS=Rattus norve... | 529 | 2e-37 | 150 | 27 | 44 | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0030424; C:axon; IDA:RGD.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0009986; C:cell surface; IDA:RGD.::GO:0030425; C:dendrite; IDA:RGD.::GO:0005788; C:endoplasmic reticulum lumen; IDA:RGD.::GO:0005615; C:extracellular space; IBA:RefGenome.::GO:0005794; C:Golgi apparatus; IDA:RGD.::GO:0031594; C:neuromuscular junction; IBA:RefGenome.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0005635; C:nuclear envelope; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:RGD.::GO:0045211; C:postsynaptic membrane; IDA:RGD.::GO:0042734; C:presynaptic membrane; IDA:RGD.::GO:0005791; C:rough endoplasmic reticulum; IDA:RGD. | | | | | | | | | | GO:0042166; F:acetylcholine binding; IDA:RGD.::GO:0003990; F:acetylcholinesterase activity; IDA:RGD.::GO:0004091; F:carboxylesterase activity; IBA:RefGenome.::GO:0033265; F:choline binding; IDA:RGD. | | | | | | | | | | GO:0006581; P:acetylcholine catabolic process; IDA:RGD.::GO:0019695; P:choline metabolic process; IDA:RGD.::GO:0070997; P:neuron death; IMP:RGD.::GO:0050772; P:positive regulation of axonogenesis; IMP:RGD.::GO:0050775; P:positive regulation of dendrite morphogenesis; IMP:RGD.::GO:0007416; P:synapse assembly; IMP:RGD.::GO:0007271; P:synaptic transmission, cholinergic; IBA:RefGenome. | 16 | P21836 | 614 | ACES_MOUSE Acetylcholinesterase OS=Mus muscul... | 529 | 3e-37 | 150 | 27 | 44 | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0030424; C:axon; IBA:RefGenome.::GO:0005605; C:basal lamina; IDA:MGI.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0009986; C:cell surface; IDA:MGI.::GO:0030425; C:dendrite; IBA:RefGenome.::GO:0005788; C:endoplasmic reticulum lumen; IBA:RefGenome.::GO:0005615; C:extracellular space; IDA:MGI.::GO:0031594; C:neuromuscular junction; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0045211; C:postsynaptic membrane; IBA:RefGenome.::GO:0042734; C:presynaptic membrane; IBA:RefGenome. | | | | | | | | | | GO:0003990; F:acetylcholinesterase activity; IDA:MGI.::GO:0004091; F:carboxylesterase activity; IBA:RefGenome.::GO:0043621; F:protein self-association; IPI:MGI. | | | | | | | | | | GO:0006581; P:acetylcholine catabolic process; IDA:MGI.::GO:0019695; P:choline metabolic process; IBA:RefGenome.::GO:0045212; P:neurotransmitter receptor biosynthetic process; IMP:MGI.::GO:0051262; P:protein tetramerization; IDA:MGI.::GO:0031623; P:receptor internalization; IMP:MGI.::GO:0050770; P:regulation of axonogenesis; IBA:RefGenome.::GO:0048814; P:regulation of dendrite morphogenesis; IBA:RefGenome.::GO:0001919; P:regulation of receptor recycling; IMP:MGI.::GO:0060041; P:retina development in camera-type eye; IMP:MGI.::GO:0007416; P:synapse assembly; IBA:RefGenome.::GO:0007271; P:synaptic transmission, cholinergic; IBA:RefGenome. | 17 | Q62765 | 843 | NLGN1_RAT Neuroligin-1 OS=Rattus norvegicus (... | 536 | 4e-37 | 152 | 27 | 43 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0009986; C:cell surface; IDA:BHF-UCL.::GO:0060076; C:excitatory synapse; IC:BHF-UCL.::GO:0032433; C:filopodium tip; IDA:BHF-UCL.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050839; F:cell adhesion molecule binding; IPI:BHF-UCL.::GO:0042043; F:neurexin family protein binding; ISS:UniProtKB.::GO:0046983; F:protein dimerization activity; IDA:BHF-UCL.::GO:0004872; F:receptor activity; IDA:BHF-UCL. | | | | | | | | | | GO:0097113; P:alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering; ISS:BHF-UCL.::GO:0016339; P:calcium-dependent cell-cell adhesion; IDA:UniProtKB.::GO:0048789; P:cytoskeletal matrix organization at active zone; IMP:BHF-UCL.::GO:0007157; P:heterophilic cell-cell adhesion; ISS:BHF-UCL.::GO:0097114; P:N-methyl-D-aspartate receptor clustering; IDA:BHF-UCL.::GO:0097115; P:neurexin clustering; ISS:BHF-UCL.::GO:0007158; P:neuron cell-cell adhesion; IDA:BHF-UCL.::GO:0045161; P:neuronal ion channel clustering; TAS:UniProtKB.::GO:0060999; P:positive regulation of dendritic spine development; IDA:BHF-UCL.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; IDA:BHF-UCL.::GO:0051491; P:positive regulation of filopodium assembly; IDA:BHF-UCL.::GO:0010740; P:positive regulation of intracellular protein kinase cascade; IDA:BHF-UCL.::GO:1900029; P:positive regulation of ruffle assembly; IDA:BHF-UCL.::GO:0051965; P:positive regulation of synapse assembly; IDA:BHF-UCL.::GO:0032230; P:positive regulation of synaptic transmission, GABAergic; IDA:BHF-UCL.::GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; IDA:BHF-UCL.::GO:1900244; P:positive regulation of synaptic vesicle endocytosis; IMP:BHF-UCL.::GO:2000302; P:positive regulation of synaptic vesicle exocytosis; IMP:BHF-UCL.::GO:0097119; P:postsynaptic density protein 95 clustering; IDA:BHF-UCL.::GO:0097104; P:postsynaptic membrane assembly; ISS:BHF-UCL.::GO:0097105; P:presynaptic membrane assembly; IDA:BHF-UCL.::GO:0051290; P:protein heterotetramerization; IDA:RGD.::GO:0051260; P:protein homooligomerization; ISS:BHF-UCL.::GO:0006605; P:protein targeting; IDA:UniProtKB.::GO:0097120; P:receptor localization to synapse; ISS:BHF-UCL.::GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; IDA:BHF-UCL.::GO:2000310; P:regulation of N-methyl-D-aspartate selective glutamate receptor activity; IDA:BHF-UCL.::GO:0097091; P:synaptic vesicle clustering; IMP:BHF-UCL.::GO:0016080; P:synaptic vesicle targeting; ISS:UniProtKB.::GO:0072553; P:terminal button organization; IMP:BHF-UCL. | 18 | Q62888 | 836 | NLGN2_RAT Neuroligin-2 OS=Rattus norvegicus (... | 523 | 4e-37 | 152 | 28 | 44 | GO:0009986; C:cell surface; IDA:BHF-UCL.::GO:0060077; C:inhibitory synapse; IDA:BHF-UCL.::GO:0005887; C:integral to plasma membrane; IDA:BHF-UCL. | | | | | | | | | | GO:0050839; F:cell adhesion molecule binding; ISS:BHF-UCL.::GO:0042043; F:neurexin family protein binding; ISS:BHF-UCL.::GO:0004872; F:receptor activity; IBA:RefGenome. | | | | | | | | | | GO:0097116; P:gephyrin clustering; ISS:BHF-UCL.::GO:0007630; P:jump response; IMP:BHF-UCL.::GO:0035641; P:locomotory exploration behavior; ISS:BHF-UCL.::GO:0050885; P:neuromuscular process controlling balance; ISS:BHF-UCL.::GO:0007158; P:neuron cell-cell adhesion; IDA:BHF-UCL.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.::GO:0097151; P:positive regulation of inhibitory postsynaptic membrane potential; IMP:BHF-UCL.::GO:0051965; P:positive regulation of synapse assembly; IDA:BHF-UCL.::GO:0032230; P:positive regulation of synaptic transmission, GABAergic; ISS:BHF-UCL.::GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; ISS:BHF-UCL.::GO:0097119; P:postsynaptic density protein 95 clustering; ISS:BHF-UCL.::GO:0097104; P:postsynaptic membrane assembly; ISS:BHF-UCL.::GO:0097105; P:presynaptic membrane assembly; IDA:BHF-UCL.::GO:0035418; P:protein localization to synapse; ISS:BHF-UCL.::GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:BHF-UCL.::GO:0019233; P:sensory perception of pain; ISS:BHF-UCL.::GO:0035176; P:social behavior; IMP:BHF-UCL.::GO:0072553; P:terminal button organization; IMP:BHF-UCL.::GO:0001966; P:thigmotaxis; IMP:BHF-UCL. | 19 | P23141 | 567 | EST1_HUMAN Liver carboxylesterase 1 OS=Homo s... | 540 | 5e-37 | 149 | 29 | 46 | GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004091; F:carboxylesterase activity; IBA:RefGenome.::GO:0080030; F:methyl indole-3-acetate esterase activity; IEA:EC.::GO:0080032; F:methyl jasmonate esterase activity; IEA:EC.::GO:0080031; F:methyl salicylate esterase activity; IEA:EC.::GO:0047374; F:methylumbelliferyl-acetate deacetylase activity; IEA:EC.::GO:0050253; F:retinyl-palmitate esterase activity; IEA:EC. | | | | | | | | | | GO:0009636; P:response to toxin; TAS:ProtInc. | 20 | P0C6R3 | 550 | EST4A_BOVIN Carboxylesterase 4A OS=Bos taurus... | 555 | 6e-37 | 148 | 26 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004091; F:carboxylesterase activity; IBA:RefGenome. | | | | | | | | | | | 21 | O62763 | 611 | ACES_FELCA Acetylcholinesterase OS=Felis catu... | 511 | 1e-36 | 148 | 27 | 44 | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003990; F:acetylcholinesterase activity; IEA:EC.::GO:0004091; F:carboxylesterase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042135; P:neurotransmitter catabolic process; IEA:UniProtKB-KW. | 22 | Q69ZK9 | 836 | NLGN2_MOUSE Neuroligin-2 OS=Mus musculus (Mou... | 523 | 1e-36 | 150 | 28 | 44 | GO:0009986; C:cell surface; ISS:BHF-UCL.::GO:0060076; C:excitatory synapse; IC:BHF-UCL.::GO:0060077; C:inhibitory synapse; IC:BHF-UCL.::GO:0005887; C:integral to plasma membrane; ISS:BHF-UCL. | | | | | | | | | | GO:0050839; F:cell adhesion molecule binding; IPI:BHF-UCL.::GO:0042043; F:neurexin family protein binding; IPI:BHF-UCL.::GO:0004872; F:receptor activity; IBA:RefGenome. | | | | | | | | | | GO:0097116; P:gephyrin clustering; IDA:BHF-UCL.::GO:0007630; P:jump response; ISS:BHF-UCL.::GO:0035641; P:locomotory exploration behavior; IMP:BHF-UCL.::GO:0050885; P:neuromuscular process controlling balance; IMP:BHF-UCL.::GO:0007158; P:neuron cell-cell adhesion; ISS:BHF-UCL.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; IMP:BHF-UCL.::GO:0097151; P:positive regulation of inhibitory postsynaptic membrane potential; IMP:BHF-UCL.::GO:0051965; P:positive regulation of synapse assembly; ISS:BHF-UCL.::GO:0032230; P:positive regulation of synaptic transmission, GABAergic; IMP:BHF-UCL.::GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; IMP:BHF-UCL.::GO:0097119; P:postsynaptic density protein 95 clustering; IDA:BHF-UCL.::GO:0097104; P:postsynaptic membrane assembly; IDA:BHF-UCL.::GO:0097105; P:presynaptic membrane assembly; IDA:BHF-UCL.::GO:0035418; P:protein localization to synapse; IDA:BHF-UCL.::GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; IMP:BHF-UCL.::GO:0002087; P:regulation of respiratory gaseous exchange by neurological system process; IGI:MGI.::GO:0019233; P:sensory perception of pain; IMP:BHF-UCL.::GO:0035176; P:social behavior; ISS:BHF-UCL.::GO:0072553; P:terminal button organization; ISS:BHF-UCL.::GO:0001966; P:thigmotaxis; ISS:BHF-UCL. | 23 | Q29499 | 584 | ACES_RABIT Acetylcholinesterase OS=Oryctolagu... | 507 | 3e-36 | 147 | 27 | 43 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003990; F:acetylcholinesterase activity; IEA:EC.::GO:0004091; F:carboxylesterase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042135; P:neurotransmitter catabolic process; IEA:UniProtKB-KW. | 24 | Q8NFZ4 | 835 | NLGN2_HUMAN Neuroligin-2 OS=Homo sapiens (Hum... | 523 | 3e-36 | 149 | 28 | 44 | GO:0009986; C:cell surface; ISS:BHF-UCL.::GO:0060077; C:inhibitory synapse; ISS:BHF-UCL.::GO:0005887; C:integral to plasma membrane; ISS:BHF-UCL.::GO:0045211; C:postsynaptic membrane; NAS:UniProtKB. | | | | | | | | | | GO:0050839; F:cell adhesion molecule binding; ISS:BHF-UCL.::GO:0042043; F:neurexin family protein binding; NAS:UniProtKB.::GO:0004872; F:receptor activity; IBA:RefGenome. | | | | | | | | | | GO:0045217; P:cell-cell junction maintenance; NAS:UniProtKB.::GO:0097116; P:gephyrin clustering; ISS:BHF-UCL.::GO:0007158; P:neuron cell-cell adhesion; ISS:BHF-UCL.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.::GO:0097151; P:positive regulation of inhibitory postsynaptic membrane potential; ISS:BHF-UCL.::GO:0051965; P:positive regulation of synapse assembly; ISS:BHF-UCL.::GO:0032230; P:positive regulation of synaptic transmission, GABAergic; ISS:BHF-UCL.::GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; ISS:BHF-UCL.::GO:0097119; P:postsynaptic density protein 95 clustering; ISS:BHF-UCL.::GO:0097104; P:postsynaptic membrane assembly; ISS:BHF-UCL.::GO:0097105; P:presynaptic membrane assembly; ISS:BHF-UCL.::GO:0035418; P:protein localization to synapse; ISS:BHF-UCL.::GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:BHF-UCL.::GO:0072553; P:terminal button organization; ISS:BHF-UCL. | 25 | Q27459 | 620 | ACE1_CAEBR Acetylcholinesterase 1 OS=Caenorha... | 492 | 4e-36 | 147 | 27 | 43 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003990; F:acetylcholinesterase activity; IEA:EC.::GO:0004091; F:carboxylesterase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042135; P:neurotransmitter catabolic process; IEA:UniProtKB-KW. | 26 | Q04791 | 557 | SASB_ANAPL Fatty acyl-CoA hydrolase precursor... | 523 | 5e-36 | 145 | 28 | 43 | | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 27 | O46421 | 566 | EST1_MACFA Liver carboxylesterase 1 OS=Macaca... | 539 | 8e-36 | 145 | 29 | 45 | GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004091; F:carboxylesterase activity; IEA:UniProtKB-KW.::GO:0080030; F:methyl indole-3-acetate esterase activity; IEA:EC.::GO:0080032; F:methyl jasmonate esterase activity; IEA:EC.::GO:0080031; F:methyl salicylate esterase activity; IEA:EC.::GO:0050253; F:retinyl-palmitate esterase activity; IEA:EC. | | | | | | | | | | | 28 | P38433 | 620 | ACE1_CAEEL Acetylcholinesterase 1 OS=Caenorha... | 493 | 3e-35 | 144 | 27 | 43 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005576; C:extracellular region; IDA:WormBase.::GO:0005626; C:insoluble fraction; IDA:WormBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0043083; C:synaptic cleft; ISS:GOC. | | | | | | | | | | GO:0003990; F:acetylcholinesterase activity; IDA:WormBase.::GO:0004091; F:carboxylesterase activity; IBA:RefGenome.::GO:0042802; F:identical protein binding; IPI:WormBase. | | | | | | | | | | GO:0001507; P:acetylcholine catabolic process in synaptic cleft; ISS:WormBase.::GO:0019695; P:choline metabolic process; IBA:RefGenome.::GO:0040012; P:regulation of locomotion; IGI:WormBase. | 29 | Q5XG92 | 561 | EST4A_HUMAN Carboxylesterase 4A OS=Homo sapie... | 528 | 3e-35 | 144 | 27 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004091; F:carboxylesterase activity; IBA:RefGenome. | | | | | | | | | | | 30 | P16303 | 565 | CES1D_RAT Carboxylesterase 1D OS=Rattus norve... | 506 | 5e-35 | 143 | 28 | 43 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005788; C:endoplasmic reticulum lumen; ISS:UniProtKB.::GO:0005811; C:lipid particle; ISS:UniProtKB. | | | | | | | | | | GO:0004091; F:carboxylesterase activity; IMP:RGD.::GO:0030339; F:fatty-acyl-ethyl-ester synthase activity; IEA:EC.::GO:0080030; F:methyl indole-3-acetate esterase activity; IEA:EC.::GO:0080032; F:methyl jasmonate esterase activity; IEA:EC.::GO:0080031; F:methyl salicylate esterase activity; IEA:EC.::GO:0050253; F:retinyl-palmitate esterase activity; IEA:EC.::GO:0004771; F:sterol esterase activity; ISS:UniProtKB.::GO:0004806; F:triglyceride lipase activity; ISS:UniProtKB. | | | | | | | | | | GO:0046464; P:acylglycerol catabolic process; ISS:UniProtKB. | 31 | Q8I034 | 545 | EST5A_FELCA Carboxylesterase 5A OS=Felis catu... | 495 | 1e-34 | 142 | 28 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004091; F:carboxylesterase activity; IEA:UniProtKB-KW.::GO:0080030; F:methyl indole-3-acetate esterase activity; IEA:EC.::GO:0080032; F:methyl jasmonate esterase activity; IEA:EC.::GO:0080031; F:methyl salicylate esterase activity; IEA:EC.::GO:0050253; F:retinyl-palmitate esterase activity; IEA:EC. | | | | | | | | | | |
