rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q00024 | 568 | PPO1_AGABI Polyphenol oxidase 1 OS=Agaricus b... | 218 | 0.018 | 41.2 | 25 | 37 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004503; F:monophenol monooxygenase activity; IEA:EC. | | | | | | | | | | GO:0042438; P:melanin biosynthetic process; IEA:UniProtKB-KW. | 32 | C7FF04 | 576 | PPO3_AGABI Polyphenol oxidase 3 OS=Agaricus b... | 254 | 0.02 | 41.2 | 22 | 35 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004503; F:monophenol monooxygenase activity; IEA:EC. | | | | | | | | | | GO:0042438; P:melanin biosynthetic process; IEA:UniProtKB-KW. | 33 | P14679 | 529 | TYRO_HUMAN Tyrosinase OS=Homo sapiens (Human)... | 333 | 0.027 | 40.4 | 21 | 35 | GO:0005798; C:Golgi-associated vesicle; TAS:ProtInc.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005764; C:lysosome; TAS:UniProtKB.::GO:0033162; C:melanosome membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0005507; F:copper ion binding; IMP:UniProtKB.::GO:0004503; F:monophenol monooxygenase activity; IDA:UniProtKB.::GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB. | | | | | | | | | | GO:0006726; P:eye pigment biosynthetic process; TAS:ProtInc.::GO:0006583; P:melanin biosynthetic process from tyrosine; TAS:ProtInc.::GO:0007601; P:visual perception; TAS:ProtInc. | 34 | H2A0L1 | 456 | TYRO2_PINMG Tyrosinase-like protein 2 OS=Pinc... | 250 | 0.039 | 40 | 26 | 40 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016491; F:oxidoreductase activity; IEA:InterPro. | | | | | | | | | | | 35 | P11344 | 533 | TYRO_MOUSE Tyrosinase OS=Mus musculus (Mouse)... | 298 | 0.068 | 39.3 | 21 | 37 | GO:0016021; C:integral to membrane; TAS:UniProtKB.::GO:0033162; C:melanosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004503; F:monophenol monooxygenase activity; TAS:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB. | | | | | | | | | | GO:0008283; P:cell proliferation; IMP:MGI.::GO:0042438; P:melanin biosynthetic process; IMP:MGI.::GO:0043473; P:pigmentation; IMP:MGI.::GO:0048538; P:thymus development; IMP:MGI. | 36 | P55027 | 534 | TYRP1_AMBME 5,6-dihydroxyindole-2-carboxylic ... | 401 | 0.078 | 39.3 | 23 | 34 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0033162; C:melanosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005507; F:copper ion binding; IEA:InterPro.::GO:0016716; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen; IEA:InterPro. | | | | | | | | | | GO:0042438; P:melanin biosynthetic process; IEA:UniProtKB-KW. | 37 | Q1DUF9 | 1662 | INO80_COCIM Putative DNA helicase INO80 OS=Co... | 128 | 0.098 | 38.9 | 24 | 46 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 38 | Q9BDE0 | 529 | TYRO_GORGO Tyrosinase OS=Gorilla gorilla gori... | 333 | 0.1 | 38.5 | 20 | 35 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0033162; C:melanosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004503; F:monophenol monooxygenase activity; IEA:EC.::GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB. | | | | | | | | | | GO:0042438; P:melanin biosynthetic process; IEA:UniProtKB-KW. | 39 | Q54QC0 | 2381 | MYBU_DICDI Myb-like protein U OS=Dictyosteliu... | 103 | 0.19 | 38.1 | 28 | 42 | | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro. | | | | | | | | | | | 40 | Q04637 | 1599 | IF4G1_HUMAN Eukaryotic translation initiation... | 145 | 0.2 | 38.1 | 27 | 36 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016281; C:eukaryotic translation initiation factor 4F complex; TAS:ProtInc. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003743; F:translation initiation factor activity; TAS:UniProtKB. | | | | | | | | | | GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.::GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; TAS:Reactome.::GO:0006446; P:regulation of translational initiation; IMP:UniProtKB. | 41 | P55025 | 540 | TYRO_ORYLA Tyrosinase OS=Oryzias latipes (Med... | 210 | 0.36 | 37 | 22 | 36 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0033162; C:melanosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004503; F:monophenol monooxygenase activity; IEA:EC. | | | | | | | | | | GO:0042438; P:melanin biosynthetic process; IEA:UniProtKB-KW. | 42 | P55024 | 529 | TYRO_CHICK Tyrosinase OS=Gallus gallus (Chick... | 301 | 0.36 | 37 | 20 | 37 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0033162; C:melanosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004503; F:monophenol monooxygenase activity; IEA:EC. | | | | | | | | | | GO:0042438; P:melanin biosynthetic process; IEA:UniProtKB-KW. | 43 | P56823 | 404 | HCYG_HELPO Hemocyanin, beta-C chain unit G OS... | 187 | 0.55 | 36.2 | 24 | 36 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0005344; F:oxygen transporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 44 | O42713 | 556 | PPO2_AGABI Polyphenol oxidase 2 OS=Agaricus b... | 216 | 0.66 | 36.2 | 22 | 36 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004503; F:monophenol monooxygenase activity; IEA:EC. | | | | | | | | | | GO:0042438; P:melanin biosynthetic process; IEA:UniProtKB-KW. | 45 | Q04604 | 532 | TYRO_PELNI Tyrosinase OS=Pelophylax nigromacu... | 207 | 0.67 | 36.2 | 24 | 38 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0033162; C:melanosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004503; F:monophenol monooxygenase activity; IEA:EC. | | | | | | | | | | GO:0042438; P:melanin biosynthetic process; IEA:UniProtKB-KW. | 46 | Q9NQT8 | 1826 | KI13B_HUMAN Kinesin-like protein KIF13B OS=Ho... | 159 | 0.81 | 36.2 | 27 | 36 | GO:0030424; C:axon; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005874; C:microtubule; IEA:UniProtKB-KW. | | | | | | | | | | GO:0071889; F:14-3-3 protein binding; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003777; F:microtubule motor activity; NAS:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB. | | | | | | | | | | GO:0007018; P:microtubule-based movement; TAS:UniProtKB.::GO:0006605; P:protein targeting; TAS:UniProtKB.::GO:0050770; P:regulation of axonogenesis; IDA:UniProtKB.::GO:0007165; P:signal transduction; NAS:UniProtKB.::GO:0042110; P:T cell activation; NAS:UniProtKB. | 47 | Q5BAZ5 | 1612 | INO80_EMENI Putative DNA helicase ino80 OS=19... | 121 | 0.88 | 35.8 | 24 | 34 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 48 | Q9Z0R4 | 1714 | ITSN1_MOUSE Intersectin-1 OS=Mus musculus (Mo... | 111 | 0.94 | 35.8 | 29 | 38 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0030139; C:endocytic vesicle; IDA:MGI.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0019209; F:kinase activator activity; IDA:MGI.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:MGI.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IDA:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IDA:MGI. | 49 | A1C9W6 | 1707 | INO80_ASPCL Putative DNA helicase ino80 OS=38... | 91 | 0.96 | 35.8 | 30 | 48 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 50 | P56825 | 208 | HCYE_SEPOF Hemocyanin, units E and F OS=Sepia... | 144 | 1.1 | 34.7 | 28 | 35 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0005344; F:oxygen transporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 51 | A4R227 | 1944 | INO80_MAGO7 Putative DNA helicase INO80 OS=bl... | 89 | 1.3 | 35.4 | 31 | 40 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 52 | Q08410 | 273 | TYRO_COTJA Tyrosinase OS=Coturnix coturnix ja... | 138 | 1.4 | 34.7 | 22 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0033162; C:melanosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004503; F:monophenol monooxygenase activity; IEA:EC. | | | | | | | | | | GO:0042438; P:melanin biosynthetic process; IEA:UniProtKB-KW. | 53 | Q00234 | 539 | TYRO_ASPOR Tyrosinase OS=Aspergillus oryzae (... | 62 | 1.5 | 35 | 35 | 47 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004503; F:monophenol monooxygenase activity; IEA:EC. | | | | | | | | | | GO:0042438; P:melanin biosynthetic process; IEA:UniProtKB-KW. | 54 | P13529 | 3141 | POLG_PPVD Genome polyprotein OS=Plum pox poty... | 176 | 1.6 | 35 | 27 | 36 | GO:0019028; C:viral capsid; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0005198; F:structural molecule activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0018144; P:RNA-protein covalent cross-linking; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.::GO:0019079; P:viral genome replication; IEA:InterPro. | 55 | Q02952 | 1782 | AKA12_HUMAN A-kinase anchor protein 12 OS=Hom... | 51 | 1.6 | 35 | 43 | 53 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0008179; F:adenylate cyclase binding; IPI:UniProtKB.::GO:0051018; F:protein kinase A binding; TAS:ProtInc. | | | | | | | | | | GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.::GO:0030819; P:positive regulation of cAMP biosynthetic process; IMP:UniProtKB.::GO:0010739; P:positive regulation of protein kinase A signaling cascade; IMP:UniProtKB.::GO:0006605; P:protein targeting; IEA:InterPro. | 56 | Q7RTP6 | 2002 | MICA3_HUMAN Protein-methionine sulfoxide oxid... | 149 | 1.9 | 35 | 24 | 34 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; ISS:UniProtKB.::GO:0071949; F:FAD binding; ISS:UniProtKB.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030042; P:actin filament depolymerization; ISS:UniProtKB.::GO:0006887; P:exocytosis; IEA:UniProtKB-KW. | 57 | Q1L8U8 | 1436 | STB1A_DANRE Histone-lysine N-methyltransferas... | 136 | 2.1 | 34.7 | 26 | 41 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 58 | Q9Y4B5 | 1905 | CC165_HUMAN Coiled-coil domain-containing pro... | 118 | 2.9 | 34.3 | 35 | 41 | | | | | | | | | | | | | | | | | | | | | | 59 | P13828 | 1772 | MSP1_PLAYO Merozoite surface protein 1 OS=Pla... | 93 | 3.7 | 33.9 | 26 | 43 | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:InterPro. | 60 | Q9NZT2 | 677 | OGFR_HUMAN Opioid growth factor receptor OS=H... | 97 | 3.7 | 33.9 | 35 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004985; F:opioid receptor activity; NAS:UniProtKB. | | | | | | | | | | GO:0001558; P:regulation of cell growth; NAS:UniProtKB. | 61 | Q9Z0P7 | 484 | SUFU_MOUSE Suppressor of fused homolog OS=Mus... | 78 | 4.9 | 33.1 | 27 | 41 | GO:0005929; C:cilium; IDA:MGI.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008013; F:beta-catenin binding; IDA:MGI. | | | | | | | | | | GO:0007368; P:determination of left/right symmetry; IMP:MGI.::GO:0001947; P:heart looping; IMP:MGI.::GO:0045879; P:negative regulation of smoothened signaling pathway; IDA:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0001843; P:neural tube closure; IMP:MGI.::GO:0043588; P:skin development; IMP:MGI.::GO:0021513; P:spinal cord dorsal/ventral patterning; IMP:MGI. |