| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | O08586 | 403 | PTEN_MOUSE Phosphatidylinositol 3,4,5-trispho... | 249 | 8e-22 | 102 | 29 | 43 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0035749; C:myelin sheath adaxonal region; IDA:BHF-UCL.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.::GO:0043220; C:Schmidt-Lanterman incisure; IDA:BHF-UCL.::GO:0019717; C:synaptosome; IDA:BHF-UCL. | | | | | | | | | | GO:0051717; F:inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030165; F:PDZ domain binding; ISS:UniProtKB.::GO:0016314; F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; ISS:UniProtKB.::GO:0051800; F:phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity; ISS:UniProtKB.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0007092; P:activation of mitotic anaphase-promoting complex activity; IMP:BHF-UCL.::GO:0001525; P:angiogenesis; IMP:MGI.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0048738; P:cardiac muscle tissue development; IMP:MGI.::GO:0032286; P:central nervous system myelin maintenance; IMP:BHF-UCL.::GO:0021955; P:central nervous system neuron axonogenesis; IMP:BHF-UCL.::GO:0060997; P:dendritic spine morphogenesis; IMP:BHF-UCL.::GO:0021542; P:dentate gyrus development; IMP:BHF-UCL.::GO:0043542; P:endothelial cell migration; IMP:MGI.::GO:0048853; P:forebrain morphogenesis; IMP:BHF-UCL.::GO:0006917; P:induction of apoptosis; IMP:MGI.::GO:0046855; P:inositol phosphate dephosphorylation; ISS:UniProtKB.::GO:0007611; P:learning or memory; IMP:BHF-UCL.::GO:0045475; P:locomotor rhythm; IMP:BHF-UCL.::GO:0060291; P:long-term synaptic potentiation; IMP:BHF-UCL.::GO:0060179; P:male mating behavior; IMP:BHF-UCL.::GO:0042711; P:maternal behavior; IMP:BHF-UCL.::GO:0033555; P:multicellular organismal response to stress; IMP:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0050771; P:negative regulation of axonogenesis; IMP:BHF-UCL.::GO:0090344; P:negative regulation of cell aging; IMP:BHF-UCL.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0045792; P:negative regulation of cell size; IMP:BHF-UCL.::GO:0061002; P:negative regulation of dendritic spine morphogenesis; IMP:BHF-UCL.::GO:0050680; P:negative regulation of epithelial cell proliferation; IMP:MGI.::GO:0090394; P:negative regulation of excitatory postsynaptic membrane potential; IMP:BHF-UCL.::GO:0051895; P:negative regulation of focal adhesion assembly; ISS:UniProtKB.::GO:0031642; P:negative regulation of myelination; IMP:MGI.::GO:0046621; P:negative regulation of organ growth; IMP:BHF-UCL.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; IMP:UniProtKB.::GO:0090071; P:negative regulation of ribosome biogenesis; IMP:BHF-UCL.::GO:2000808; P:negative regulation of synaptic vesicle clustering; IMP:BHF-UCL.::GO:0007270; P:neuron-neuron synaptic transmission; IMP:BHF-UCL.::GO:0046856; P:phosphatidylinositol dephosphorylation; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; IMP:BHF-UCL.::GO:0097107; P:postsynaptic density assembly; IMP:BHF-UCL.::GO:0060134; P:prepulse inhibition; IMP:BHF-UCL.::GO:0097105; P:presynaptic membrane assembly; IMP:BHF-UCL.::GO:0060736; P:prostate gland growth; IMP:MGI.::GO:0043491; P:protein kinase B signaling cascade; IMP:UniProtKB.::GO:0002902; P:regulation of B cell apoptotic process; IMP:MGI.::GO:0033032; P:regulation of myeloid cell apoptotic process; IMP:MGI.::GO:0060024; P:rhythmic synaptic transmission; IMP:BHF-UCL.::GO:0035176; P:social behavior; IMP:BHF-UCL.::GO:0060074; P:synapse maturation; IMP:BHF-UCL. | 2 | P60484 | 403 | PTEN_HUMAN Phosphatidylinositol 3,4,5-trispho... | 249 | 8e-22 | 102 | 29 | 43 | GO:0042995; C:cell projection; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0009898; C:internal side of plasma membrane; IDA:UniProtKB.::GO:0035749; C:myelin sheath adaxonal region; ISS:BHF-UCL.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.::GO:0043220; C:Schmidt-Lanterman incisure; ISS:BHF-UCL.::GO:0019717; C:synaptosome; ISS:BHF-UCL. | | | | | | | | | | GO:0010997; F:anaphase-promoting complex binding; IPI:BHF-UCL.::GO:0051717; F:inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity; IDA:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030165; F:PDZ domain binding; IPI:UniProtKB.::GO:0016314; F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; IDA:UniProtKB.::GO:0051800; F:phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity; IDA:UniProtKB.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; IDA:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0007092; P:activation of mitotic anaphase-promoting complex activity; IDA:BHF-UCL.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0060070; P:canonical Wnt receptor signaling pathway; IDA:BHF-UCL.::GO:0008283; P:cell proliferation; TAS:UniProtKB.::GO:0032286; P:central nervous system myelin maintenance; ISS:BHF-UCL.::GO:0021955; P:central nervous system neuron axonogenesis; ISS:BHF-UCL.::GO:0060997; P:dendritic spine morphogenesis; ISS:BHF-UCL.::GO:0021542; P:dentate gyrus development; ISS:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0048853; P:forebrain morphogenesis; ISS:BHF-UCL.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0046855; P:inositol phosphate dephosphorylation; IDA:UniProtKB.::GO:0007611; P:learning or memory; ISS:BHF-UCL.::GO:0045475; P:locomotor rhythm; ISS:BHF-UCL.::GO:0033555; P:multicellular organismal response to stress; ISS:BHF-UCL.::GO:0050771; P:negative regulation of axonogenesis; ISS:BHF-UCL.::GO:0030336; P:negative regulation of cell migration; IMP:UniProtKB.::GO:0045792; P:negative regulation of cell size; ISS:BHF-UCL.::GO:0031658; P:negative regulation of cyclin-dependent protein kinase activity involved in G1/S; IDA:BHF-UCL.::GO:0061002; P:negative regulation of dendritic spine morphogenesis; ISS:BHF-UCL.::GO:0090394; P:negative regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.::GO:0051895; P:negative regulation of focal adhesion assembly; IMP:UniProtKB.::GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; IDA:BHF-UCL.::GO:0046621; P:negative regulation of organ growth; ISS:BHF-UCL.::GO:0014067; P:negative regulation of phosphatidylinositol 3-kinase cascade; TAS:BHF-UCL.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; IMP:UniProtKB.::GO:0001933; P:negative regulation of protein phosphorylation; IDA:BHF-UCL.::GO:2000808; P:negative regulation of synaptic vesicle clustering; ISS:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007270; P:neuron-neuron synaptic transmission; ISS:BHF-UCL.::GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0008284; P:positive regulation of cell proliferation; ISS:BHF-UCL.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.::GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.::GO:0097107; P:postsynaptic density assembly; ISS:BHF-UCL.::GO:0060134; P:prepulse inhibition; ISS:BHF-UCL.::GO:0097105; P:presynaptic membrane assembly; ISS:BHF-UCL.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0050821; P:protein stabilization; IDA:BHF-UCL.::GO:0060024; P:rhythmic synaptic transmission; ISS:BHF-UCL.::GO:0035176; P:social behavior; ISS:BHF-UCL.::GO:0060074; P:synapse maturation; ISS:BHF-UCL.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome. | 3 | P60483 | 403 | PTEN_CANFA Phosphatidylinositol 3,4,5-trispho... | 249 | 8e-22 | 102 | 29 | 43 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051717; F:inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030165; F:PDZ domain binding; ISS:UniProtKB.::GO:0016314; F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; ISS:UniProtKB.::GO:0051800; F:phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity; ISS:UniProtKB.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; ISS:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007417; P:central nervous system development; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0046855; P:inositol phosphate dephosphorylation; ISS:UniProtKB.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0051895; P:negative regulation of focal adhesion assembly; ISS:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0046856; P:phosphatidylinositol dephosphorylation; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0010975; P:regulation of neuron projection development; ISS:UniProtKB. | 4 | P53916 | 434 | TEP1_YEAST Probable phosphatidylinositol 3,4,... | 258 | 5e-20 | 96.7 | 27 | 43 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0016314; F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; IEA:EC.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0030476; P:ascospore wall assembly; IMP:SGD. | 5 | Q54JL7 | 639 | CNRN_DICDI Phosphatidylinositol 3,4,5-trispho... | 240 | 2e-19 | 95.9 | 29 | 42 | | | | | | | | | | | GO:0016314; F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; IEA:EC.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0030835; P:negative regulation of actin filament depolymerization; IMP:dictyBase.::GO:0030818; P:negative regulation of cAMP biosynthetic process; IMP:dictyBase.::GO:0014066; P:regulation of phosphatidylinositol 3-kinase cascade; IMP:dictyBase. | 6 | Q4R6N0 | 566 | TPTE2_MACFA Phosphatidylinositol 3,4,5-trisph... | 241 | 2e-16 | 87 | 29 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005216; F:ion channel activity; IEA:InterPro.::GO:0016314; F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; IEA:EC.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | | 7 | Q8T9S7 | 533 | PTEN_DICDI Phosphatidylinositol 3,4,5-trispho... | 296 | 0.000000000000003 | 82.4 | 24 | 41 | GO:0051285; C:cell cortex of cell tip; IDA:dictyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0031254; C:trailing edge; IDA:dictyBase. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0016314; F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; TAS:dictyBase.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0007015; P:actin filament organization; TAS:dictyBase.::GO:0031152; P:aggregation involved in sorocarp development; TAS:dictyBase.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006928; P:cellular component movement; IMP:dictyBase.::GO:0030010; P:establishment of cell polarity; TAS:dictyBase.::GO:0007188; P:G-protein signaling, coupled to cAMP nucleotide second messenger; IDA:dictyBase.::GO:0050919; P:negative chemotaxis; IMP:dictyBase.::GO:0046856; P:phosphatidylinositol dephosphorylation; TAS:dictyBase.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:dictyBase.::GO:0051272; P:positive regulation of cellular component movement; TAS:dictyBase.::GO:0045761; P:regulation of adenylate cyclase activity; IGI:dictyBase.::GO:0022604; P:regulation of cell morphogenesis; IMP:dictyBase.::GO:0031272; P:regulation of pseudopodium assembly; IMP:dictyBase. | 8 | Q9PUT6 | 402 | PTEN_XENLA Phosphatidylinositol 3,4,5-trispho... | 238 | 0.000000000000008 | 80.5 | 27 | 42 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051717; F:inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity; ISS:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030165; F:PDZ domain binding; ISS:UniProtKB.::GO:0016314; F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; ISS:UniProtKB.::GO:0051800; F:phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity; ISS:UniProtKB.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; ISS:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0046855; P:inositol phosphate dephosphorylation; ISS:UniProtKB.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0051895; P:negative regulation of focal adhesion assembly; ISS:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0046856; P:phosphatidylinositol dephosphorylation; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0010975; P:regulation of neuron projection development; ISS:UniProtKB.::GO:0031647; P:regulation of protein stability; ISS:UniProtKB. | 9 | Q6XPS3 | 522 | TPTE2_HUMAN Phosphatidylinositol 3,4,5-trisph... | 242 | 0.000000000004 | 72.8 | 28 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005216; F:ion channel activity; IEA:InterPro.::GO:0016314; F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; IEA:EC.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | | 10 | O94526 | 348 | PTEN_SCHPO Phosphatidylinositol 3,4,5-trispho... | 60 | 0.00000000009 | 67.8 | 48 | 75 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005739; C:mitochondrion; IDA:PomBase. | | | | | | | | | | GO:0016314; F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; IDA:PomBase.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0009992; P:cellular water homeostasis; IMP:PomBase.::GO:0046488; P:phosphatidylinositol metabolic process; IMP:PomBase.::GO:0007165; P:signal transduction; IC:PomBase.::GO:0007033; P:vacuole organization; IMP:PomBase. | 11 | P56180 | 551 | TPTE_HUMAN Putative tyrosine-protein phosphat... | 309 | 0.0000000005 | 66.2 | 25 | 39 | GO:0016021; C:integral to membrane; TAS:ProtInc. | | | | | | | | | | GO:0005216; F:ion channel activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; TAS:ProtInc. | 12 | O13632 | 330 | PVH1_SCHPO Tyrosine-protein phosphatase yvh1 ... | 69 | 0.00006 | 49.3 | 30 | 55 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; ISS:PomBase.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0000027; P:ribosomal large subunit assembly; ISS:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase. | 13 | Q80TZ3 | 938 | AUXI_MOUSE Putative tyrosine-protein phosphat... | 92 | 0.00006 | 50.1 | 29 | 46 | | | | | | | | | | | GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | | 14 | Q04205 | 1744 | TENS_CHICK Tensin OS=Gallus gallus (Chicken).... | 90 | 0.12 | 39.7 | 29 | 49 | GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 15 | Q27974 | 910 | AUXI_BOVIN Putative tyrosine-protein phosphat... | 92 | 0.0001 | 49.3 | 29 | 46 | | | | | | | | | | | GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | | 16 | Q9HBL0 | 1735 | TENS1_HUMAN Tensin-1 OS=Homo sapiens (Human).... | 101 | 0.0001 | 49.3 | 30 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:MGI. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 17 | O75061 | 913 | AUXI_HUMAN Putative tyrosine-protein phosphat... | 92 | 0.0001 | 48.9 | 29 | 45 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome. | 18 | Q9BVJ7 | 150 | DUS23_HUMAN Dual specificity protein phosphat... | 52 | 0.0001 | 46.2 | 42 | 58 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | | 19 | Q99KY4 | 1305 | GAK_MOUSE Cyclin-G-associated kinase OS=Mus m... | 271 | 0.0002 | 48.9 | 22 | 34 | GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW. | 20 | Q66GT5 | 193 | PTPM1_MOUSE Protein-tyrosine phosphatase mito... | 58 | 0.0002 | 46.6 | 40 | 60 | | | | | | | | | | | | | | | | | | | | | | 21 | P0C089 | 193 | PTPM1_RAT Protein-tyrosine phosphatase mitoch... | 58 | 0.0002 | 46.6 | 40 | 60 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | GO:0046855; P:inositol phosphate dephosphorylation; IBA:RefGenome. | 22 | P97874 | 1305 | GAK_RAT Cyclin-G-associated kinase OS=Rattus ... | 271 | 0.0002 | 48.5 | 22 | 34 | GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030332; F:cyclin binding; IDA:RGD.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW. | 23 | Q9GLM4 | 1715 | TENS1_BOVIN Tensin-1 OS=Bos taurus (Bovine). ... | 101 | 0.0003 | 48.1 | 29 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 24 | Q8WUK0 | 201 | PTPM1_HUMAN Protein-tyrosine phosphatase mito... | 49 | 0.0005 | 45.4 | 41 | 61 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | GO:0046855; P:inositol phosphate dephosphorylation; IBA:RefGenome. | 25 | Q68CZ2 | 1445 | TENS3_HUMAN Tensin-3 OS=Homo sapiens (Human).... | 64 | 0.022 | 42 | 30 | 56 | GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | | 26 | Q9ZQP1 | 337 | DSP8_ARATH Putative dual specificity protein ... | 71 | 0.0005 | 46.2 | 31 | 51 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | | 27 | Q6NT99 | 150 | DUS23_MOUSE Dual specificity protein phosphat... | 52 | 0.001 | 43.5 | 40 | 56 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | | 28 | Q8K330 | 649 | SSH3_MOUSE Protein phosphatase Slingshot homo... | 77 | 0.001 | 46.2 | 32 | 49 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | GO:0008064; P:regulation of actin polymerization or depolymerization; IBA:RefGenome.::GO:0050770; P:regulation of axonogenesis; IBA:RefGenome.::GO:0010591; P:regulation of lamellipodium assembly; IBA:RefGenome. | 29 | Q5SSZ5 | 1440 | TENS3_MOUSE Tensin-3 OS=Mus musculus (Mouse).... | 64 | 0.031 | 41.6 | 30 | 56 | GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0016477; P:cell migration; IMP:MGI.::GO:0048286; P:lung alveolus development; IMP:MGI.::GO:0008284; P:positive regulation of cell proliferation; IMP:MGI. | 30 | Q86BN8 | 200 | PTPM1_DROME Protein-tyrosine phosphatase mito... | 42 | 0.002 | 43.1 | 43 | 64 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | GO:0006200; P:ATP catabolic process; IMP:FlyBase.::GO:0046855; P:inositol phosphate dephosphorylation; IBA:RefGenome. | 31 | Q5XIS1 | 652 | SSH3_RAT Protein phosphatase Slingshot homolo... | 77 | 0.003 | 44.3 | 32 | 49 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | GO:0008064; P:regulation of actin polymerization or depolymerization; IBA:RefGenome.::GO:0050770; P:regulation of axonogenesis; IBA:RefGenome.::GO:0010591; P:regulation of lamellipodium assembly; IBA:RefGenome. |
