rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
511 | A2QCH3 | 346 | MKAR_ASPNC 3-ketoacyl-CoA reductase OS=Asperg... | 195 | 0.031 | 38.9 | 23 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 512 | Q9N126 | 312 | RDH8_BOVIN Retinol dehydrogenase 8 OS=Bos tau... | 221 | 0.031 | 38.9 | 24 | 41 | GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:InterPro.::GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006703; P:estrogen biosynthetic process; IEA:InterPro.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; IEA:UniProtKB-KW. | 513 | P51656 | 344 | DHB1_MOUSE Estradiol 17-beta-dehydrogenase 1 ... | 136 | 0.031 | 38.9 | 27 | 43 | | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 514 | A6T8N3 | 240 | FOLM_KLEP7 Dihydrofolate reductase folM OS=78... | 266 | 0.032 | 38.5 | 22 | 42 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 515 | Q556J2 | 334 | KDSR_DICDI 3-ketodihydrosphingosine reductase... | 249 | 0.033 | 38.9 | 25 | 39 | GO:0042406; C:extrinsic to endoplasmic reticulum membrane; ISS:dictyBase. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; ISS:dictyBase.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030148; P:sphingolipid biosynthetic process; ISS:dictyBase. | 516 | Q3SXM5 | 330 | HSDL1_HUMAN Inactive hydroxysteroid dehydroge... | 192 | 0.034 | 38.9 | 21 | 42 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro. | | | | | | | | | | | 517 | P28845 | 292 | DHI1_HUMAN Corticosteroid 11-beta-dehydrogena... | 197 | 0.035 | 38.5 | 25 | 43 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; TAS:Reactome.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006704; P:glucocorticoid biosynthetic process; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.] | 518 | P51657 | 344 | DHB1_RAT Estradiol 17-beta-dehydrogenase 1 OS... | 202 | 0.035 | 38.9 | 27 | 40 | GO:0005829; C:cytosol; IDA:RGD. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:RGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IDA:RGD. | | | | | | | | | | GO:0060348; P:bone development; IEP:RGD.::GO:0071248; P:cellular response to metal ion; IEP:RGD.::GO:0006703; P:estrogen biosynthetic process; IDA:RGD.::GO:0061370; P:testosterone biosynthetic process; IDA:RGD. | 519 | Q09851 | 296 | AYR1_SCHPO NADPH-dependent 1-acyldihydroxyace... | 205 | 0.036 | 38.5 | 26 | 41 | GO:0005783; C:endoplasmic reticulum; IDA:PomBase.::GO:0000329; C:fungal-type vacuole membrane; IDA:PomBase.::GO:0005794; C:Golgi apparatus; IDA:PomBase.::GO:0005739; C:mitochondrion; ISS:PomBase. | | | | | | | | | | GO:0000140; F:acylglycerone-phosphate reductase activity; ISS:PomBase.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0006654; P:phosphatidic acid biosynthetic process; ISS:PomBase. | 520 | A6ZLA1 | 347 | MKAR_YEAS7 3-ketoacyl-CoA reductase OS=Saccha... | 243 | 0.041 | 38.5 | 22 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 521 | B3LN00 | 347 | MKAR_YEAS1 3-ketoacyl-CoA reductase OS=Saccha... | 243 | 0.041 | 38.5 | 22 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 522 | Q66KC4 | 417 | HSDL2_XENTR Hydroxysteroid dehydrogenase-like... | 121 | 0.044 | 38.5 | 28 | 50 | GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0032934; F:sterol binding; IEA:InterPro. | | | | | | | | | | | 523 | A5PJF6 | 330 | HSDL1_BOVIN Inactive hydroxysteroid dehydroge... | 212 | 0.046 | 38.5 | 20 | 42 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro. | | | | | | | | | | | 524 | Q4R5G7 | 312 | DHB12_MACFA Estradiol 17-beta-dehydrogenase 1... | 201 | 0.046 | 38.1 | 23 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 525 | Q9EQ06 | 298 | DHB11_MOUSE Estradiol 17-beta-dehydrogenase 1... | 94 | 0.051 | 38.1 | 29 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 526 | Q5E9H7 | 312 | DHB12_BOVIN Estradiol 17-beta-dehydrogenase 1... | 202 | 0.058 | 38.1 | 23 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 527 | O74959 | 339 | YJCD_SCHPO Uncharacterized oxidoreductase C73... | 93 | 0.059 | 38.1 | 30 | 47 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 528 | Q7M3I4 | 292 | DHI1_RABIT Corticosteroid 11-beta-dehydrogena... | 198 | 0.064 | 37.7 | 26 | 41 | GO:0005789; C:endoplasmic reticulum membrane; NAS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:UniProtKB. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008211; P:glucocorticoid metabolic process; NAS:UniProtKB.] | 529 | Q05114 | 254 | ADH_DROWI Alcohol dehydrogenase OS=Drosophila... | 198 | 0.065 | 37.7 | 23 | 39 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. | 530 | Q9U8S9 | 254 | ADH_DROPU Alcohol dehydrogenase OS=Drosophila... | 198 | 0.065 | 37.7 | 23 | 39 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0046164; P:alcohol catabolic process; ISS:UniProtKB. | 531 | Q9NG40 | 254 | ADH_DROIN Alcohol dehydrogenase OS=Drosophila... | 198 | 0.065 | 37.7 | 23 | 39 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0046164; P:alcohol catabolic process; ISS:UniProtKB. | 532 | Q9NG42 | 254 | ADH_DROEQ Alcohol dehydrogenase OS=Drosophila... | 198 | 0.065 | 37.7 | 23 | 39 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0046164; P:alcohol catabolic process; ISS:UniProtKB. | 533 | O70503 | 312 | DHB12_MOUSE Estradiol 17-beta-dehydrogenase 1... | 205 | 0.078 | 37.7 | 23 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0031012; C:extracellular matrix; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005518; F:collagen binding; IDA:MGI.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0001968; F:fibronectin binding; IDA:MGI.::GO:0008201; F:heparin binding; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030198; P:extracellular matrix organization; IDA:MGI.::GO:0010811; P:positive regulation of cell-substrate adhesion; IDA:MGI.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 534 | Q01782 | 288 | PTR1_LEIMA Pteridine reductase 1 OS=Leishmani... | 98 | 0.086 | 37.4 | 30 | 50 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0047040; F:pteridine reductase activity; IEA:EC. | | | | | | | | | | GO:0031427; P:response to methotrexate; IEA:UniProtKB-KW. | 535 | Q6YN16 | 418 | HSDL2_HUMAN Hydroxysteroid dehydrogenase-like... | 134 | 0.097 | 37.4 | 25 | 46 | GO:0005777; C:peroxisome; IDA:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0032934; F:sterol binding; IEA:InterPro. | | | | | | | | | | | 536 | O32099 | 243 | BZRD_BACSU Benzil reductase ((S)-benzoin form... | 195 | 0.1 | 37 | 22 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:EC. | | | | | | | | | | | 537 | Q5R6U1 | 325 | DRS7B_PONAB Dehydrogenase/reductase SDR famil... | 207 | 0.1 | 37.4 | 25 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 538 | Q6IAN0 | 325 | DRS7B_HUMAN Dehydrogenase/reductase SDR famil... | 207 | 0.1 | 37.4 | 25 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 539 | P0CR36 | 335 | TSC10_CRYNJ 3-ketodihydrosphingosine reductas... | 184 | 0.11 | 37.4 | 23 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 540 | P0AFP4 | 269 | YBBO_ECOLI Uncharacterized oxidoreductase ybb... | 196 | 0.11 | 37 | 26 | 39 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 541 | P0AFP5 | 269 | YBBO_ECOL6 Uncharacterized oxidoreductase ybb... | 196 | 0.11 | 37 | 26 | 39 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | |