rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
391 | Q5XG41 | 318 | DH12A_XENLA Estradiol 17-beta-dehydrogenase 1... | 207 | 0.0001 | 46.2 | 25 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 392 | Q8FHD2 | 248 | YDFG_ECOL6 NADP-dependent L-serine/L-allo-thr... | 189 | 0.0001 | 45.8 | 23 | 44 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 393 | Q71R50 | 255 | DHR11_CHICK Dehydrogenase/reductase SDR famil... | 201 | 0.0002 | 45.8 | 26 | 42 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 394 | O77667 | 404 | DHI2_BOVIN Corticosteroid 11-beta-dehydrogena... | 203 | 0.0002 | 46.2 | 23 | 41 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 395 | Q6CVS4 | 346 | MKAR_KLULA 3-ketoacyl-CoA reductase OS=1267 /... | 237 | 0.0002 | 45.8 | 24 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 396 | P39831 | 248 | YDFG_ECOLI NADP-dependent 3-hydroxy acid dehy... | 189 | 0.0002 | 45.4 | 23 | 44 | | | | | | | | | | | GO:0035527; F:3-hydroxypropionate dehydrogenase (NADP+) activity; IDA:EcoCyc.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0031132; F:serine 3-dehydrogenase activity; IDA:EcoCyc. | | | | | | | | | | GO:0006212; P:uracil catabolic process; IMP:EcoCyc. | 397 | Q6UWP2 | 260 | DHR11_HUMAN Dehydrogenase/reductase SDR famil... | 207 | 0.0002 | 45.4 | 26 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 398 | Q6PUF3 | 287 | DHI1L_DANRE Hydroxysteroid 11-beta-dehydrogen... | 197 | 0.0002 | 45.4 | 24 | 42 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016229; F:steroid dehydrogenase activity; ISS:ZFIN. | | | | | | | | | | | 399 | Q3YZ12 | 270 | HCAB_SHISS 3-phenylpropionate-dihydrodiol/cin... | 184 | 0.0002 | 45.1 | 29 | 44 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW. | 400 | Q0CY11 | 353 | MKAR_ASPTN 3-ketoacyl-CoA reductase OS=Asperg... | 195 | 0.0003 | 45.4 | 25 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 401 | Q89AM1 | 260 | FABI_BUCBP Enoyl-[acyl-carrier-protein] reduc... | 260 | 0.0003 | 45.1 | 23 | 41 | | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.::GO:0030497; P:fatty acid elongation; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.] | 402 | Q8X505 | 248 | YDFG_ECO57 NADP-dependent L-serine/L-allo-thr... | 189 | 0.0003 | 45.1 | 23 | 44 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 403 | P50203 | 248 | PHAB_ACISR Acetoacetyl-CoA reductase OS=Acine... | 262 | 0.0003 | 45.1 | 25 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018454; F:acetoacetyl-CoA reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0042619; P:poly-hydroxybutyrate biosynthetic process; IEA:InterPro. | 404 | Q5B0R9 | 346 | MKAR_EMENI 3-ketoacyl-CoA reductase OS=194 / ... | 190 | 0.0003 | 45.1 | 24 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 405 | Q7Z9I3 | 253 | YCP8_SCHPO Uncharacterized oxidoreductase C66... | 206 | 0.0003 | 44.7 | 23 | 41 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0033554; P:cellular response to stress; IEP:PomBase. | 406 | Q9NZC7 | 414 | WWOX_HUMAN WW domain-containing oxidoreductas... | 123 | 0.0003 | 45.1 | 32 | 48 | GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005739; C:mitochondrion; ISS:BHF-UCL.::GO:0005634; C:nucleus; IDA:BHF-UCL. | | | | | | | | | | GO:0050662; F:coenzyme binding; TAS:UniProtKB.::GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; NAS:UniProtKB.::GO:0046983; F:protein dimerization activity; TAS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:BHF-UCL.::GO:0006917; P:induction of apoptosis; ISS:BHF-UCL.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0048705; P:skeletal system morphogenesis; ISS:BHF-UCL.::GO:0008202; P:steroid metabolic process; TAS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 407 | Q9VXJ0 | 598 | DHB4_DROME Peroxisomal multifunctional enzyme... | 193 | 0.0003 | 45.4 | 24 | 42 | GO:0005777; C:peroxisome; IC:FlyBase. | | | | | | | | | | GO:0080023; F:3R-hydroxyacyl-CoA dehydratase activity; IDA:FlyBase.::GO:0004300; F:enoyl-CoA hydratase activity; IDA:FlyBase.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:EC.::GO:0042803; F:protein homodimerization activity; IDA:FlyBase. | | | | | | | | | | GO:0033540; P:fatty acid beta-oxidation using acyl-CoA oxidase; IC:FlyBase. | 408 | A1L1W4 | 339 | RD10A_DANRE Retinol dehydrogenase 10-A OS=Dan... | 216 | 0.0003 | 45.1 | 23 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 409 | Q6BQK1 | 328 | TSC10_DEBHA 3-ketodihydrosphingosine reductas... | 198 | 0.0004 | 45.1 | 24 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 410 | B5Z114 | 270 | HCAB_ECO5E 3-phenylpropionate-dihydrodiol/cin... | 213 | 0.0004 | 44.7 | 28 | 43 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW. | 411 | Q8XA72 | 270 | HCAB_ECO57 3-phenylpropionate-dihydrodiol/cin... | 213 | 0.0004 | 44.7 | 28 | 43 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW. | 412 | Q8AVY8 | 318 | DH12B_XENLA Estradiol 17-beta-dehydrogenase 1... | 207 | 0.0004 | 44.7 | 24 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 413 | Q0VFE7 | 309 | DRS7B_XENTR Dehydrogenase/reductase SDR famil... | 244 | 0.0004 | 44.7 | 25 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 414 | O57314 | 312 | DHB12_ANAPL Estradiol 17-beta-dehydrogenase 1... | 195 | 0.0004 | 44.7 | 25 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 415 | P40580 | 263 | BZRD_YEAST Benzil reductase ((S)-benzoin form... | 203 | 0.0004 | 44.7 | 24 | 42 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:EC. | | | | | | | | | | | 416 | Q9ZUH5 | 296 | SDR2_ARATH Short-chain dehydrogenase/reductas... | 49 | 1.4 | 33.5 | 39 | 55 | GO:0005829; C:cytosol; IDA:TAIR. | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IDA:TAIR.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 417 | Q9ZDG4 | 261 | FABI_RICPR Enoyl-[acyl-carrier-protein] reduc... | 197 | 0.0005 | 44.3 | 23 | 39 | | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.] | 418 | Q8N5I4 | 330 | DHRSX_HUMAN Dehydrogenase/reductase SDR famil... | 217 | 0.0006 | 44.3 | 24 | 42 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 419 | Q1WNP0 | 328 | DHB1_PANTR Estradiol 17-beta-dehydrogenase 1 ... | 131 | 0.0006 | 43.9 | 27 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006703; P:estrogen biosynthetic process; IEA:InterPro. | 420 | Q16698 | 335 | DECR_HUMAN 2,4-dienoyl-CoA reductase, mitocho... | 262 | 0.0007 | 43.9 | 26 | 44 | GO:0005759; C:mitochondrial matrix; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0008670; F:2,4-dienoyl-CoA reductase (NADPH) activity; IDA:UniProtKB.::GO:0070402; F:NADPH binding; IDA:UniProtKB.::GO:0016651; F:oxidoreductase activity, acting on NADH or NADPH; TAS:Reactome. | | | | | | | | | | GO:0006635; P:fatty acid beta-oxidation; IDA:UniProtKB.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB. | 421 | Q05069 | 258 | FABI_NOSS1 Enoyl-[acyl-carrier-protein] reduc... | 201 | 0.0007 | 43.5 | 24 | 39 | | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.] |