rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
571 | Q8TC12 | 318 | RDH11_HUMAN Retinol dehydrogenase 11 OS=Homo ... | 93 | 1.3 | 34.3 | 30 | 43 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0052650; F:NADP-retinol dehydrogenase activity; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0042574; P:retinal metabolic process; IDA:MGI.::GO:0042572; P:retinol metabolic process; ISS:UniProtKB.::GO:0008202; P:steroid metabolic process; TAS:Reactome. | 572 | Q9NZC7 | 414 | WWOX_HUMAN WW domain-containing oxidoreductas... | 129 | 1.4 | 34.3 | 26 | 36 | GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005739; C:mitochondrion; ISS:BHF-UCL.::GO:0005634; C:nucleus; IDA:BHF-UCL. | | | | | | | | | | GO:0050662; F:coenzyme binding; TAS:UniProtKB.::GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; NAS:UniProtKB.::GO:0046983; F:protein dimerization activity; TAS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:BHF-UCL.::GO:0006917; P:induction of apoptosis; ISS:BHF-UCL.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0048705; P:skeletal system morphogenesis; ISS:BHF-UCL.::GO:0008202; P:steroid metabolic process; TAS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 573 | Q42850 | 395 | PORB_HORVU Protochlorophyllide reductase B, c... | 174 | 1.4 | 34.3 | 27 | 40 | GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016630; F:protochlorophyllide reductase activity; IEA:EC. | | | | | | | | | | GO:0015995; P:chlorophyll biosynthetic process; IEA:UniProtKB-KW.::GO:0015979; P:photosynthesis; IEA:UniProtKB-KW. | 574 | B2WMJ3 | 341 | MKAR_PYRTR 3-ketoacyl-CoA reductase OS=fungus... | 207 | 1.4 | 34.3 | 23 | 38 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 575 | A6SG70 | 331 | MKAR_BOTFB 3-ketoacyl-CoA reductase OS=cinere... | 167 | 1.5 | 33.9 | 26 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 576 | Q58NB6 | 319 | DHRS9_MOUSE Dehydrogenase/reductase SDR famil... | 194 | 1.5 | 33.9 | 22 | 41 | GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0005792; C:microsome; ISS:UniProtKB. | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB.::GO:0047035; F:testosterone dehydrogenase (NAD+) activity; ISS:UniProtKB. | | | | | | | | | | GO:0042904; P:9-cis-retinoic acid biosynthetic process; ISS:UniProtKB. | 577 | Q8W3D9 | 402 | PORB_ORYSJ Protochlorophyllide reductase B, c... | 169 | 1.5 | 33.9 | 28 | 39 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016630; F:protochlorophyllide reductase activity; IEA:EC. | | | | | | | | | | GO:0015995; P:chlorophyll biosynthetic process; IEA:UniProtKB-KW.::GO:0015979; P:photosynthesis; IEA:UniProtKB-KW. | 578 | Q8BYK4 | 316 | RDH12_MOUSE Retinol dehydrogenase 12 OS=Mus m... | 215 | 1.6 | 33.9 | 24 | 39 | GO:0005622; C:intracellular; ISS:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0042572; P:retinol metabolic process; ISS:UniProtKB.::GO:0007601; P:visual perception; IEA:UniProtKB-KW. | 579 | Q9ERI6 | 334 | RDH14_MOUSE Retinol dehydrogenase 14 OS=Mus m... | 214 | 1.6 | 33.9 | 25 | 39 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 580 | P18297 | 262 | SPRE_RAT Sepiapterin reductase OS=Rattus norv... | 219 | 1.7 | 33.5 | 24 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004757; F:sepiapterin reductase activity; IDA:UniProtKB. | | | | | | | | | | GO:0010033; P:response to organic substance; IMP:RGD.::GO:0006729; P:tetrahydrobiopterin biosynthetic process; IMP:RGD. | 581 | P16232 | 288 | DHI1_RAT Corticosteroid 11-beta-dehydrogenase... | 202 | 1.8 | 33.5 | 22 | 41 | GO:0045177; C:apical part of cell; IDA:RGD.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.::GO:0031965; C:nuclear membrane; IDA:RGD.::GO:0005791; C:rough endoplasmic reticulum; IDA:RGD. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; IDA:RGD.::GO:0050661; F:NADP binding; IDA:RGD.::GO:0005496; F:steroid binding; IPI:RGD. | | | | | | | | | | GO:0071392; P:cellular response to estradiol stimulus; IEP:RGD.::GO:0006704; P:glucocorticoid biosynthetic process; IDA:RGD.::GO:0006713; P:glucocorticoid catabolic process; IDA:RGD.::GO:0018963; P:phthalate metabolic process; IEP:RGD.::GO:0043456; P:regulation of pentose-phosphate shunt; IDA:RGD.::GO:0031667; P:response to nutrient levels; IEP:RGD.] | 582 | Q820V5 | 250 | FABI_ENTFA Enoyl-[acyl-carrier-protein] reduc... | 57 | 1.9 | 33.5 | 37 | 49 | | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.] | 583 | Q66KC4 | 417 | HSDL2_XENTR Hydroxysteroid dehydrogenase-like... | 118 | 1.9 | 33.9 | 27 | 42 | GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0032934; F:sterol binding; IEA:InterPro. | | | | | | | | | | | 584 | A7F8T1 | 334 | MKAR_SCLS1 3-ketoacyl-CoA reductase OS=mold) ... | 167 | 1.9 | 33.5 | 26 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 585 | Q8VBZ0 | 335 | DHRSX_MOUSE Dehydrogenase/reductase SDR famil... | 119 | 1.9 | 33.5 | 29 | 39 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 586 | Q2YC56 | 288 | FOLD_NITMU Bifunctional protein FolD OS=Nitro... | 77 | 2.1 | 33.5 | 29 | 52 | | | | | | | | | | | GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 587 | Q5F389 | 414 | WWOX_CHICK WW domain-containing oxidoreductas... | 126 | 2.3 | 33.5 | 25 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 588 | Q6CE86 | 372 | TSC10_YARLI 3-ketodihydrosphingosine reductas... | 208 | 2.3 | 33.5 | 23 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 589 | Q5R9W5 | 414 | WWOX_PONAB WW domain-containing oxidoreductas... | 130 | 2.3 | 33.5 | 25 | 37 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 590 | Q10130 | 378 | DHS5_CAEEL Uncharacterized oxidoreductase dhs... | 208 | 2.7 | 33.1 | 26 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 591 | A6QP05 | 317 | DHR12_BOVIN Dehydrogenase/reductase SDR famil... | 63 | 2.7 | 33.1 | 30 | 46 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 592 | Q91WL8 | 414 | WWOX_MOUSE WW domain-containing oxidoreductas... | 121 | 2.8 | 33.1 | 26 | 36 | GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; IDA:BHF-UCL. | | | | | | | | | | GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:BHF-UCL.::GO:0006917; P:induction of apoptosis; IDA:MGI.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0001649; P:osteoblast differentiation; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0048705; P:skeletal system morphogenesis; IMP:MGI.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 593 | Q05069 | 258 | FABI_NOSS1 Enoyl-[acyl-carrier-protein] reduc... | 60 | 2.8 | 33.1 | 33 | 48 | | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.] | 594 | Q01289 | 399 | POR_PEA Protochlorophyllide reductase, chloro... | 108 | 3.2 | 33.1 | 31 | 43 | GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016630; F:protochlorophyllide reductase activity; IEA:EC. | | | | | | | | | | GO:0015995; P:chlorophyll biosynthetic process; IEA:UniProtKB-KW.::GO:0015979; P:photosynthesis; IEA:UniProtKB-KW. | 595 | Q6P7R8 | 312 | DHB12_RAT Estradiol 17-beta-dehydrogenase 12 ... | 240 | 3.2 | 32.7 | 24 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 596 | Q6PAY8 | 417 | HSDL2_XENLA Hydroxysteroid dehydrogenase-like... | 118 | 3.4 | 33.1 | 26 | 42 | GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0032934; F:sterol binding; IEA:InterPro. | | | | | | | | | | | 597 | A7TMJ2 | 347 | MKAR_VANPO 3-ketoacyl-CoA reductase OS=(Kluyv... | 205 | 3.6 | 32.7 | 23 | 37 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 598 | Q1J118 | 288 | FOLD1_DEIGD Bifunctional protein FolD 1 OS=De... | 68 | 3.8 | 32.7 | 32 | 46 | | | | | | | | | | | GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 599 | P11348 | 241 | DHPR_RAT Dihydropteridine reductase OS=Rattus... | 66 | 3.8 | 32.3 | 32 | 56 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0019717; C:synaptosome; IDA:RGD. | | | | | | | | | | GO:0004155; F:6,7-dihydropteridine reductase activity; IMP:UniProtKB.::GO:0070404; F:NADH binding; IPI:RGD.::GO:0070402; F:NADPH binding; IMP:RGD.::GO:0042803; F:protein homodimerization activity; IDA:RGD. | | | | | | | | | | GO:0035690; P:cellular response to drug; IEP:RGD.::GO:0006559; P:L-phenylalanine catabolic process; IEP:RGD.::GO:0001889; P:liver development; IEP:RGD.::GO:0010044; P:response to aluminum ion; IEP:RGD.::GO:0033762; P:response to glucagon stimulus; IEP:RGD.::GO:0010288; P:response to lead ion; IEP:RGD.::GO:0006729; P:tetrahydrobiopterin biosynthetic process; IMP:UniProtKB. | 600 | A8E5C5 | 324 | DS7CA_DANRE Dehydrogenase/reductase SDR famil... | 195 | 3.9 | 32.7 | 20 | 34 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 601 | P23170 | 258 | 25KD_SARPE Development-specific 25 kDa protei... | 94 | 4.3 | 32.3 | 24 | 44 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | |