rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
541 | P49327 | 2511 | FAS_HUMAN Fatty acid synthase OS=Homo sapiens... | 156 | 0.54 | 35.8 | 23 | 42 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0004317; F:3-hydroxypalmitoyl-[acyl-carrier-protein dehydratase activity; IEA:EC.::GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; IEA:EC.::GO:0004315; F:3-oxoacyl-[acyl-carrier-protein synthase activity; IEA:EC.::GO:0004313; F:[acyl-carrier-protein S-acetyltransferase activity; IEA:EC.::GO:0004314; F:[acyl-carrier-protein S-malonyltransferase activity; IEA:EC.::GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0004319; F:enoyl-[acyl-carrier-protein reductase (NADPH, B-specific) activity; IEA:EC.::GO:0016295; F:myristoyl-[acyl-carrier-protein hydrolase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004320; F:oleoyl-[acyl-carrier-protein hydrolase activity; IEA:EC.::GO:0016296; F:palmitoyl-[acyl-carrier-protein hydrolase activity; IEA:EC.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.]::GO:0005515; F:protein binding; IPI:UniProtKB.]::GO:0008270; F:zinc ion binding; IEA:InterPro.] | | | | | | | | | | GO:0006112; P:energy reserve metabolic process; TAS:Reactome.]::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.]::GO:0035338; P:long-chain fatty-acyl-CoA biosynthetic process; TAS:Reactome.]::GO:0015939; P:pantothenate metabolic process; TAS:Reactome.]::GO:0031325; P:positive regulation of cellular metabolic process; TAS:Reactome.]::GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.] | 542 | A9NE96 | 277 | FOLD_ACHLI Bifunctional protein FolD OS=Achol... | 41 | 0.55 | 35 | 34 | 59 | | | | | | | | | | | GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 543 | P21218 | 401 | PORB_ARATH Protochlorophyllide reductase B, c... | 112 | 0.56 | 35.4 | 30 | 43 | GO:0009707; C:chloroplast outer membrane; IEA:UniProtKB-SubCell.::GO:0009535; C:chloroplast thylakoid membrane; IDA:TAIR. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016630; F:protochlorophyllide reductase activity; IEA:EC. | | | | | | | | | | GO:0015995; P:chlorophyll biosynthetic process; IEA:UniProtKB-KW.::GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.::GO:0009723; P:response to ethylene stimulus; IEP:TAIR. | 544 | Q92IC6 | 260 | FABI_RICCN Enoyl-[acyl-carrier-protein] reduc... | 84 | 0.56 | 35 | 32 | 42 | | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.] | 545 | Q9M2E2 | 296 | SDR1_ARATH (+)-neomenthol dehydrogenase OS=Ar... | 87 | 0.62 | 35 | 26 | 45 | GO:0005829; C:cytosol; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0047501; F:(+)-neomenthol dehydrogenase activity; IDA:TAIR.::GO:0047504; F:(-)-menthol dehydrogenase activity; IDA:TAIR.::GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IDA:TAIR.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006952; P:defense response; IMP:TAIR.::GO:0080167; P:response to karrikin; IEP:TAIR. | 546 | Q6QA33 | 311 | DH12B_DANRE Estradiol 17-beta-dehydrogenase 1... | 253 | 0.58 | 35.4 | 24 | 37 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 547 | B5YA73 | 283 | FOLD_DICT6 Bifunctional protein FolD OS=Dicty... | 74 | 0.58 | 35 | 36 | 49 | | | | | | | | | | | GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 548 | P09368 | 476 | PUT1_YEAST Proline dehydrogenase, mitochondri... | 67 | 0.6 | 35.4 | 24 | 45 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004657; F:proline dehydrogenase activity; IDA:SGD. | | | | | | | | | | GO:0006537; P:glutamate biosynthetic process; TAS:SGD.::GO:0010133; P:proline catabolic process to glutamate; IMP:SGD. | 549 | Q8R536 | 262 | SPRE_MERUN Sepiapterin reductase OS=Meriones ... | 219 | 0.6 | 35 | 24 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004757; F:sepiapterin reductase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006729; P:tetrahydrobiopterin biosynthetic process; IEA:InterPro. | 550 | Q2TPA8 | 490 | HSDL2_MOUSE Hydroxysteroid dehydrogenase-like... | 210 | 0.61 | 35.4 | 25 | 40 | GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0032934; F:sterol binding; IEA:InterPro. | | | | | | | | | | | 551 | Q9ZDG4 | 261 | FABI_RICPR Enoyl-[acyl-carrier-protein] reduc... | 84 | 0.63 | 35 | 32 | 42 | | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.] | 552 | Q6R0J2 | 292 | DHI1_MESAU Corticosteroid 11-beta-dehydrogena... | 182 | 0.63 | 35 | 24 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 553 | O77769 | 302 | DHRS3_BOVIN Short-chain dehydrogenase/reducta... | 198 | 0.64 | 35 | 26 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 554 | P58381 | 268 | FABI2_RHIME Enoyl-[acyl-carrier-protein] redu... | 134 | 0.64 | 35 | 27 | 43 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.] | 555 | Q6YN16 | 418 | HSDL2_HUMAN Hydroxysteroid dehydrogenase-like... | 210 | 0.72 | 35 | 23 | 40 | GO:0005777; C:peroxisome; IDA:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0032934; F:sterol binding; IEA:InterPro. | | | | | | | | | | | 556 | A4IFM3 | 313 | DR9C7_BOVIN Short-chain dehydrogenase/reducta... | 195 | 0.73 | 35 | 23 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 557 | Q59987 | 322 | POR_SYNY3 Light-dependent protochlorophyllide... | 102 | 0.74 | 35 | 30 | 41 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016630; F:protochlorophyllide reductase activity; IEA:EC. | | | | | | | | | | GO:0015995; P:chlorophyll biosynthetic process; IEA:UniProtKB-KW.::GO:0015979; P:photosynthesis; IEA:UniProtKB-KW. | 558 | O75911 | 302 | DHRS3_HUMAN Short-chain dehydrogenase/reducta... | 198 | 0.8 | 34.7 | 26 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; TAS:ProtInc.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042572; P:retinol metabolic process; TAS:UniProtKB.::GO:0007601; P:visual perception; TAS:ProtInc. | 559 | Q5RA68 | 418 | HSDL2_PONAB Hydroxysteroid dehydrogenase-like... | 210 | 0.81 | 35 | 23 | 40 | GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0032934; F:sterol binding; IEA:InterPro. | | | | | | | | | | | 560 | Q86SE5 | 291 | RALYL_HUMAN RNA-binding Raly-like protein OS=... | 126 | 0.84 | 34.7 | 26 | 47 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | | 561 | Q41249 | 398 | PORA_CUCSA Protochlorophyllide reductase, chl... | 112 | 0.89 | 34.7 | 29 | 45 | GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016630; F:protochlorophyllide reductase activity; IEA:EC. | | | | | | | | | | GO:0015995; P:chlorophyll biosynthetic process; IEA:UniProtKB-KW.::GO:0015979; P:photosynthesis; IEA:UniProtKB-KW. | 562 | P58380 | 272 | FABI1_RHIME Enoyl-[acyl-carrier-protein] redu... | 135 | 0.97 | 34.3 | 24 | 44 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.] | 563 | Q8NBN7 | 331 | RDH13_HUMAN Retinol dehydrogenase 13 OS=Homo ... | 220 | 0.97 | 34.7 | 23 | 38 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 564 | B0SU50 | 188 | EFP_LEPBP Elongation factor P OS=Paris). GN=e... | 75 | 1 | 33.9 | 31 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0043043; P:peptide biosynthetic process; IEA:InterPro. | 565 | B0SII2 | 188 | EFP_LEPBA Elongation factor P OS=Leptospira b... | 75 | 1 | 33.9 | 31 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0043043; P:peptide biosynthetic process; IEA:InterPro. | 566 | Q9ZKW1 | 271 | VDLC_HELPJ Probable short-chain type dehydrog... | 192 | 1.1 | 34.3 | 24 | 38 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 567 | P47844 | 277 | CBR1_RABIT Carbonyl reductase [NADPH] 1 OS=Or... | 244 | 1.1 | 34.3 | 24 | 36 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC. | | | | | | | | | | GO:0017144; P:drug metabolic process; ISS:UniProtKB.::GO:0042373; P:vitamin K metabolic process; ISS:UniProtKB. | 568 | A5E0R1 | 350 | MKAR_LODEL 3-ketoacyl-CoA reductase OS=NBRC 1... | 217 | 1.2 | 34.3 | 26 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 569 | A1C6J8 | 345 | MKAR_ASPCL 3-ketoacyl-CoA reductase OS=3887 /... | 211 | 1.2 | 34.3 | 27 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 570 | Q6GI75 | 256 | FABI_STAAR Enoyl-[acyl-carrier-protein] reduc... | 66 | 1.2 | 33.9 | 35 | 47 | | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; ISS:UniProtKB.::GO:0004319; F:enoyl-[acyl-carrier-protein reductase (NADPH, B-specific) activity; IEA:EC.::GO:0050661; F:NADP binding; IDA:UniProtKB. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.]::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.] | 571 | Q8TC12 | 318 | RDH11_HUMAN Retinol dehydrogenase 11 OS=Homo ... | 93 | 1.3 | 34.3 | 30 | 43 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0052650; F:NADP-retinol dehydrogenase activity; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0042574; P:retinal metabolic process; IDA:MGI.::GO:0042572; P:retinol metabolic process; ISS:UniProtKB.::GO:0008202; P:steroid metabolic process; TAS:Reactome. |