rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
421 | Q5NVG2 | 300 | DHB11_PONAB Estradiol 17-beta-dehydrogenase 1... | 200 | 0.004 | 41.6 | 25 | 40 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 422 | Q9EQ06 | 298 | DHB11_MOUSE Estradiol 17-beta-dehydrogenase 1... | 200 | 0.004 | 41.6 | 26 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 423 | Q8NBQ5 | 300 | DHB11_HUMAN Estradiol 17-beta-dehydrogenase 1... | 200 | 0.005 | 41.6 | 25 | 40 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005811; C:lipid particle; IDA:UniProtKB. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006710; P:androgen catabolic process; IDA:HGNC.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 424 | A2RVM0 | 322 | TIC32_ARATH Short-chain dehydrogenase TIC 32,... | 213 | 0.005 | 42 | 27 | 39 | GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 425 | A1L1W4 | 339 | RD10A_DANRE Retinol dehydrogenase 10-A OS=Dan... | 226 | 0.005 | 41.6 | 23 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 426 | Q4JK73 | 300 | DHB11_MACFA Estradiol 17-beta-dehydrogenase 1... | 200 | 0.005 | 41.6 | 24 | 41 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 427 | P80702 | 257 | DIDH_COMTE 3-alpha-hydroxysteroid dehydrogena... | 99 | 0.005 | 41.2 | 30 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047042; F:androsterone dehydrogenase (B-specific) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW. | | | | | | | | | | | 428 | Q16698 | 335 | DECR_HUMAN 2,4-dienoyl-CoA reductase, mitocho... | 272 | 0.006 | 41.6 | 25 | 42 | GO:0005759; C:mitochondrial matrix; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0008670; F:2,4-dienoyl-CoA reductase (NADPH) activity; IDA:UniProtKB.::GO:0070402; F:NADPH binding; IDA:UniProtKB.::GO:0016651; F:oxidoreductase activity, acting on NADH or NADPH; TAS:Reactome. | | | | | | | | | | GO:0006635; P:fatty acid beta-oxidation; IDA:UniProtKB.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB. | 429 | Q8AVY8 | 318 | DH12B_XENLA Estradiol 17-beta-dehydrogenase 1... | 202 | 0.006 | 41.2 | 25 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 430 | O13908 | 261 | YF3H_SCHPO Uncharacterized oxidoreductase C22... | 259 | 0.008 | 40.8 | 24 | 39 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0033554; P:cellular response to stress; IEP:PomBase. | 431 | P55434 | 248 | Y4EK_RHISN Uncharacterized short-chain type d... | 192 | 0.008 | 40.8 | 26 | 42 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 432 | Q07530 | 308 | YD114_YEAST Uncharacterized oxidoreductase YD... | 196 | 0.008 | 40.8 | 23 | 41 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 433 | O77667 | 404 | DHI2_BOVIN Corticosteroid 11-beta-dehydrogena... | 204 | 0.009 | 41.2 | 25 | 40 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 434 | A5DND6 | 341 | MKAR_PICGU 3-ketoacyl-CoA reductase OS=1539 /... | 209 | 0.009 | 40.8 | 27 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 435 | P50168 | 427 | DHI2_SHEEP Corticosteroid 11-beta-dehydrogena... | 203 | 0.01 | 40.8 | 24 | 40 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 436 | O05730 | 284 | VDLC_HELPY Probable short-chain type dehydrog... | 199 | 0.01 | 40.4 | 25 | 40 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 437 | Q11150 | 251 | Y484_MYCTU Uncharacterized oxidoreductase Rv0... | 206 | 0.011 | 40.4 | 25 | 41 | GO:0005886; C:plasma membrane; IDA:MTBBASE. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 438 | Q9Y7P2 | 503 | YCKF_SCHPO Uncharacterized protein C1450.15 O... | 193 | 0.011 | 40.8 | 27 | 41 | GO:0005789; C:endoplasmic reticulum membrane; ISS:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016651; F:oxidoreductase activity, acting on NADH or NADPH; ISS:PomBase.::GO:0000234; F:phosphoethanolamine N-methyltransferase activity; ISS:PomBase. | | | | | | | | | | GO:0006666; P:3-keto-sphinganine metabolic process; ISS:PomBase.::GO:0006506; P:GPI anchor biosynthetic process; ISS:PomBase. | 439 | Q03133 | 3172 | ERYA3_SACER Erythronolide synthase, modules 5... | 196 | 0.011 | 41.2 | 28 | 41 | | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0047879; F:erythronolide synthase activity; IEA:EC.::GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro. | | | | | | | | | | GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW. | 440 | B8E335 | 281 | FOLD_DICTD Bifunctional protein FolD OS=Dicty... | 125 | 0.012 | 40.4 | 32 | 46 | | | | | | | | | | | GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 441 | Q17703 | 314 | STDH1_CAEEL Putative steroid dehydrogenase 1 ... | 209 | 0.013 | 40.4 | 25 | 36 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 442 | Q2UET3 | 346 | MKAR_ASPOR 3-ketoacyl-CoA reductase OS=Asperg... | 209 | 0.014 | 40.4 | 26 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 443 | Q1WNP0 | 328 | DHB1_PANTR Estradiol 17-beta-dehydrogenase 1 ... | 191 | 0.014 | 40.4 | 26 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006703; P:estrogen biosynthetic process; IEA:InterPro. | 444 | O74732 | 338 | ERG27_SCHPO 3-keto-steroid reductase OS=Schiz... | 236 | 0.014 | 40.4 | 23 | 39 | GO:0005789; C:endoplasmic reticulum membrane; ISS:PomBase. | | | | | | | | | | GO:0000253; F:3-keto sterol reductase activity; ISS:PomBase.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006696; P:ergosterol biosynthetic process; ISS:PomBase. | 445 | Q1RH28 | 262 | FABI_RICBR Enoyl-[acyl-carrier-protein] reduc... | 82 | 0.015 | 40 | 34 | 45 | | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.] | 446 | Q6P3L6 | 319 | DH12A_DANRE Estradiol 17-beta-dehydrogenase 1... | 211 | 0.015 | 40 | 23 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 447 | P37059 | 387 | DHB2_HUMAN Estradiol 17-beta-dehydrogenase 2 ... | 200 | 0.016 | 40.4 | 28 | 45 | GO:0005789; C:endoplasmic reticulum membrane; TAS:ProtInc.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; TAS:BHF-UCL.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IDA:UniProtKB. | | | | | | | | | | GO:0032526; P:response to retinoic acid; IDA:BHF-UCL. | 448 | P56937 | 341 | DHB7_HUMAN 3-keto-steroid reductase OS=Homo s... | 94 | 0.017 | 40 | 33 | 48 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000253; F:3-keto sterol reductase activity; IEA:EC.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; TAS:ProtInc.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome. | 449 | Q17704 | 315 | STDH3_CAEEL Putative steroid dehydrogenase 3 ... | 206 | 0.017 | 40 | 23 | 37 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 450 | P14061 | 328 | DHB1_HUMAN Estradiol 17-beta-dehydrogenase 1 ... | 191 | 0.018 | 40 | 26 | 40 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; TAS:Reactome.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006703; P:estrogen biosynthetic process; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 451 | O34782 | 263 | YVRD_BACSU Uncharacterized oxidoreductase yvr... | 186 | 0.019 | 39.7 | 22 | 41 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | |