rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
601 | P0AFS3 | 240 | FOLM_ECOLI Dihydrofolate reductase folM OS=Es... | 170 | 1 | 34.3 | 21 | 42 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IDA:EcoliWiki.::GO:0071172; F:dihydromonapterin reductase activity; IDA:EcoCyc.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0009257; P:10-formyltetrahydrofolate biosynthetic process; IMP:EcoliWiki.::GO:0046656; P:folic acid biosynthetic process; IMP:EcoliWiki.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 602 | B1IQY4 | 240 | FOLM_ECOLC Dihydrofolate reductase folM OS=Es... | 170 | 1 | 34.3 | 21 | 42 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 603 | A8A0E8 | 240 | FOLM_ECOHS Dihydrofolate reductase folM OS=Es... | 170 | 1 | 34.3 | 21 | 42 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 604 | P0AFS4 | 240 | FOLM_ECO57 Dihydrofolate reductase folM OS=Es... | 170 | 1 | 34.3 | 21 | 42 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 605 | Q00672 | 254 | ADH_DRONI Alcohol dehydrogenase OS=Drosophila... | 154 | 1.2 | 33.9 | 23 | 43 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. | 606 | P09369 | 254 | ADH2_DROMO Alcohol dehydrogenase 2 OS=Drosoph... | 154 | 1.3 | 33.9 | 25 | 42 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. | 607 | Q83RC9 | 240 | FOLM_SHIFL Dihydrofolate reductase folM OS=Sh... | 170 | 1.3 | 33.9 | 21 | 41 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 608 | Q0T4H1 | 240 | FOLM_SHIF8 Dihydrofolate reductase folM OS=Sh... | 170 | 1.3 | 33.9 | 21 | 41 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 609 | P55435 | 248 | Y4EL_RHISN Uncharacterized short-chain type d... | 177 | 1.3 | 33.9 | 24 | 41 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 610 | Q6MGB5 | 259 | DHB8_RAT Estradiol 17-beta-dehydrogenase 8 OS... | 132 | 1.4 | 33.9 | 23 | 45 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC. | | | | | | | | | | GO:0006703; P:estrogen biosynthetic process; ISS:UniProtKB.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 611 | Q5H2A4 | 345 | RUVB_XANOR Holliday junction ATP-dependent DN... | 196 | 1.4 | 33.9 | 22 | 39 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0009378; F:four-way junction helicase activity; IEA:InterPro. | | | | | | | | | | GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009432; P:SOS response; IEA:UniProtKB-KW. | 612 | B2STK0 | 345 | RUVB_XANOP Holliday junction ATP-dependent DN... | 196 | 1.4 | 33.9 | 22 | 39 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0009378; F:four-way junction helicase activity; IEA:InterPro. | | | | | | | | | | GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009432; P:SOS response; IEA:UniProtKB-KW. | 613 | Q2P575 | 345 | RUVB_XANOM Holliday junction ATP-dependent DN... | 196 | 1.4 | 33.9 | 22 | 39 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0009378; F:four-way junction helicase activity; IEA:InterPro. | | | | | | | | | | GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009432; P:SOS response; IEA:UniProtKB-KW. | 614 | Q8VCC1 | 269 | PGDH_MOUSE 15-hydroxyprostaglandin dehydrogen... | 159 | 1.5 | 33.9 | 25 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0097070; P:ductus arteriosus closure; IMP:UniProtKB.::GO:0007565; P:female pregnancy; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0030728; P:ovulation; ISS:UniProtKB.::GO:0007567; P:parturition; ISS:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; ISS:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB. | 615 | B2SYK2 | 354 | RUVB_BURPP Holliday junction ATP-dependent DN... | 166 | 1.5 | 33.9 | 25 | 40 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0009378; F:four-way junction helicase activity; IEA:InterPro. | | | | | | | | | | GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009432; P:SOS response; IEA:UniProtKB-KW. | 616 | Q5F389 | 414 | WWOX_CHICK WW domain-containing oxidoreductas... | 137 | 1.5 | 33.9 | 26 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 617 | Q8PHV2 | 346 | RUVB_XANAC Holliday junction ATP-dependent DN... | 196 | 1.5 | 33.9 | 22 | 39 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0009378; F:four-way junction helicase activity; IEA:InterPro. | | | | | | | | | | GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009432; P:SOS response; IEA:UniProtKB-KW. | 618 | A1WVC0 | 98 | RL23_HALHL 50S ribosomal protein L23 OS=halop... | 62 | 1.5 | 32 | 34 | 48 | GO:0005840; C:ribosome; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.::GO:0003735; F:structural constituent of ribosome; IEA:InterPro. | | | | | | | | | | GO:0006412; P:translation; IEA:InterPro. | 619 | Q1RBJ2 | 240 | FOLM_ECOUT Dihydrofolate reductase folM OS=Es... | 170 | 1.7 | 33.5 | 21 | 42 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 620 | A1ABF1 | 240 | FOLM_ECOK1 Dihydrofolate reductase folM OS=Es... | 170 | 1.7 | 33.5 | 21 | 42 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 621 | Q13UC0 | 355 | RUVB_BURXL Holliday junction ATP-dependent DN... | 150 | 1.7 | 33.9 | 25 | 40 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0009378; F:four-way junction helicase activity; IEA:InterPro. | | | | | | | | | | GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009432; P:SOS response; IEA:UniProtKB-KW. | 622 | P47844 | 277 | CBR1_RABIT Carbonyl reductase [NADPH] 1 OS=Or... | 163 | 1.7 | 33.5 | 28 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC. | | | | | | | | | | GO:0017144; P:drug metabolic process; ISS:UniProtKB.::GO:0042373; P:vitamin K metabolic process; ISS:UniProtKB. | 623 | Q91WL8 | 414 | WWOX_MOUSE WW domain-containing oxidoreductas... | 203 | 1.7 | 33.9 | 26 | 37 | GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; IDA:BHF-UCL. | | | | | | | | | | GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:BHF-UCL.::GO:0006917; P:induction of apoptosis; IDA:MGI.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0001649; P:osteoblast differentiation; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0048705; P:skeletal system morphogenesis; IMP:MGI.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 624 | B0RPY7 | 346 | RUVB_XANCB Holliday junction ATP-dependent DN... | 196 | 1.8 | 33.9 | 22 | 39 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0009378; F:four-way junction helicase activity; IEA:InterPro. | | | | | | | | | | GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009432; P:SOS response; IEA:UniProtKB-KW. | 625 | Q99MZ7 | 303 | PECR_MOUSE Peroxisomal trans-2-enoyl-CoA redu... | 120 | 1.8 | 33.5 | 27 | 40 | GO:0005739; C:mitochondrion; IDA:UniProtKB.::GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0019166; F:trans-2-enoyl-CoA reductase (NADPH) activity; IEA:EC. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 626 | Q8FHB1 | 240 | FOLM_ECOL6 Dihydrofolate reductase folM OS=Es... | 170 | 1.9 | 33.5 | 21 | 42 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 627 | Q8P6E7 | 346 | RUVB_XANCP Holliday junction ATP-dependent DN... | 196 | 1.9 | 33.5 | 22 | 39 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0009378; F:four-way junction helicase activity; IEA:InterPro. | | | | | | | | | | GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009432; P:SOS response; IEA:UniProtKB-KW. | 628 | Q1D2J8 | 343 | RUVB_MYXXD Holliday junction ATP-dependent DN... | 164 | 2.2 | 33.5 | 26 | 41 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0009378; F:four-way junction helicase activity; IEA:InterPro. | | | | | | | | | | GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009432; P:SOS response; IEA:UniProtKB-KW. | 629 | Q1RH28 | 262 | FABI_RICBR Enoyl-[acyl-carrier-protein] reduc... | 192 | 2.4 | 33.1 | 25 | 39 | | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.] | 630 | P22082 | 1703 | SNF2_YEAST Transcription regulatory protein S... | 54 | 2.4 | 33.9 | 37 | 54 | GO:0016514; C:SWI/SNF complex; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008094; F:DNA-dependent ATPase activity; IDA:SGD.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0070577; F:histone acetyl-lysine binding; IDA:SGD.::GO:0031492; F:nucleosomal DNA binding; IDA:SGD. | | | | | | | | | | GO:0043044; P:ATP-dependent chromatin remodeling; IDA:SGD.::GO:0044109; P:cellular alcohol catabolic process; IMP:SGD.::GO:0006261; P:DNA-dependent DNA replication; IMP:SGD.::GO:0006302; P:double-strand break repair; IMP:SGD.::GO:0042766; P:nucleosome mobilization; IDA:SGD.::GO:0031496; P:positive regulation of mating type switching; IMP:SGD.::GO:0061412; P:positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation; IMP:SGD.::GO:0042148; P:strand invasion; IMP:SGD.::GO:0005987; P:sucrose catabolic process; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 631 | A4W9Z4 | 240 | FOLM_ENT38 Dihydrofolate reductase folM OS=En... | 191 | 2.4 | 33.1 | 21 | 42 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. |