| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
331 | B2B3L4 | 340 | MKAR_PODAN 3-ketoacyl-CoA reductase OS=(Pleur... | 230 | 0.00002 | 48.9 | 24 | 38 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 332 | P39884 | 106 | YDFG_DICNO Probable NADP-dependent dehydrogen... | 95 | 0.00003 | 46.2 | 37 | 47 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 333 | Q28IU1 | 320 | DHB12_XENTR Estradiol 17-beta-dehydrogenase 1... | 173 | 0.00003 | 48.5 | 24 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 334 | Q7Z9I2 | 253 | YCP9_SCHPO Uncharacterized oxidoreductase C66... | 194 | 0.00003 | 48.1 | 24 | 45 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 335 | O70351 | 261 | HCD2_RAT 3-hydroxyacyl-CoA dehydrogenase type... | 204 | 0.00003 | 48.1 | 24 | 42 | | | | | | | | | | | GO:0047015; F:3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity; IEA:EC.::GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:EC.::GO:0018454; F:acetoacetyl-CoA reductase activity; IDA:RGD.::GO:0001540; F:beta-amyloid binding; IDA:RGD.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:RGD.::GO:0030331; F:estrogen receptor binding; IPI:RGD.::GO:0042802; F:identical protein binding; IDA:RGD.::GO:0051287; F:NAD binding; IDA:RGD.::GO:0005496; F:steroid binding; IDA:RGD. | | | | | | | | | | GO:0007569; P:cell aging; IEP:RGD.::GO:0033327; P:Leydig cell differentiation; IEP:RGD.::GO:0051289; P:protein homotetramerization; IDA:RGD.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW. | 336 | Q92EK7 | 248 | Y452_LISIN Uncharacterized oxidoreductase Lin... | 187 | 0.00003 | 48.1 | 23 | 44 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 337 | O74470 | 261 | YQC8_SCHPO Uncharacterized oxidoreductase C17... | 190 | 0.00003 | 48.1 | 26 | 47 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0033554; P:cellular response to stress; IEP:PomBase. | 338 | P28845 | 292 | DHI1_HUMAN Corticosteroid 11-beta-dehydrogena... | 198 | 0.00004 | 48.1 | 27 | 43 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; TAS:Reactome.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006704; P:glucocorticoid biosynthetic process; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.] | 339 | Q6PKH6 | 230 | DR4L2_HUMAN Dehydrogenase/reductase SDR famil... | 197 | 0.00004 | 47.8 | 28 | 45 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 340 | P39483 | 261 | DHG2_BACME Glucose 1-dehydrogenase 2 OS=Bacil... | 184 | 0.00005 | 47.8 | 24 | 45 | | | | | | | | | | | GO:0047936; F:glucose 1-dehydrogenase [NAD(P) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.] | | | | | | | | | | | 341 | Q8MI29 | 277 | CBR1_MACFA Carbonyl reductase [NADPH] 1 OS=Ma... | 152 | 0.00005 | 47.8 | 28 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC. | | | | | | | | | | GO:0017144; P:drug metabolic process; ISS:UniProtKB.::GO:0042373; P:vitamin K metabolic process; ISS:UniProtKB. | 342 | Q9CQ62 | 335 | DECR_MOUSE 2,4-dienoyl-CoA reductase, mitocho... | 214 | 0.00005 | 47.8 | 22 | 42 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0008670; F:2,4-dienoyl-CoA reductase (NADPH) activity; IEA:EC. | | | | | | | | | | | 343 | Q9Z2M4 | 292 | DECR2_RAT Peroxisomal 2,4-dienoyl-CoA reducta... | 143 | 0.00005 | 47.8 | 27 | 45 | GO:0005777; C:peroxisome; IDA:HGNC. | | | | | | | | | | GO:0008670; F:2,4-dienoyl-CoA reductase (NADPH) activity; IDA:RGD.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 344 | P51976 | 406 | DHI2_RABIT Corticosteroid 11-beta-dehydrogena... | 191 | 0.00006 | 47.8 | 28 | 44 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 345 | Q7M3I4 | 292 | DHI1_RABIT Corticosteroid 11-beta-dehydrogena... | 201 | 0.00006 | 47.4 | 25 | 45 | GO:0005789; C:endoplasmic reticulum membrane; NAS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:UniProtKB. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008211; P:glucocorticoid metabolic process; NAS:UniProtKB.] | 346 | O08756 | 261 | HCD2_MOUSE 3-hydroxyacyl-CoA dehydrogenase ty... | 121 | 0.00006 | 47.4 | 27 | 48 | GO:0005739; C:mitochondrion; IDA:UniProtKB. | | | | | | | | | | GO:0047015; F:3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity; IEA:EC.::GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008033; P:tRNA processing; IEA:UniProtKB-KW. | 347 | Q8AVY8 | 318 | DH12B_XENLA Estradiol 17-beta-dehydrogenase 1... | 169 | 0.00006 | 47.4 | 24 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 348 | Q6CVS4 | 346 | MKAR_KLULA 3-ketoacyl-CoA reductase OS=1267 /... | 218 | 0.00007 | 47.4 | 26 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 349 | Q6P3L6 | 319 | DH12A_DANRE Estradiol 17-beta-dehydrogenase 1... | 169 | 0.00007 | 47.4 | 24 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 350 | Q5XG41 | 318 | DH12A_XENLA Estradiol 17-beta-dehydrogenase 1... | 169 | 0.00008 | 47 | 25 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 351 | Q2H1V7 | 342 | MKAR_CHAGB 3-ketoacyl-CoA reductase OS=6347 /... | 196 | 0.00009 | 47 | 26 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 352 | A4IGM4 | 286 | DHI1L_XENTR Hydroxysteroid 11-beta-dehydrogen... | 189 | 0.00009 | 47 | 27 | 46 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 353 | Q6BQK1 | 328 | TSC10_DEBHA 3-ketodihydrosphingosine reductas... | 201 | 0.00009 | 47 | 21 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 354 | Q9M2E2 | 296 | SDR1_ARATH (+)-neomenthol dehydrogenase OS=Ar... | 172 | 0.0001 | 47 | 23 | 42 | GO:0005829; C:cytosol; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0047501; F:(+)-neomenthol dehydrogenase activity; IDA:TAIR.::GO:0047504; F:(-)-menthol dehydrogenase activity; IDA:TAIR.::GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IDA:TAIR.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006952; P:defense response; IMP:TAIR.::GO:0080167; P:response to karrikin; IEP:TAIR. | 355 | Q9RA05 | 277 | LIMC_RHOER (-)-trans-carveol dehydrogenase OS... | 147 | 0.0001 | 46.6 | 29 | 48 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:EC. | | | | | | | | | | | 356 | O02691 | 261 | HCD2_BOVIN 3-hydroxyacyl-CoA dehydrogenase ty... | 201 | 0.0001 | 46.6 | 23 | 43 | | | | | | | | | | | GO:0047015; F:3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity; IEA:EC.::GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008033; P:tRNA processing; IEA:UniProtKB-KW. | 357 | O31642 | 251 | YJDA_BACSU Uncharacterized oxidoreductase yjd... | 191 | 0.0001 | 46.2 | 26 | 45 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 358 | Q9WVK3 | 303 | PECR_RAT Peroxisomal trans-2-enoyl-CoA reduct... | 187 | 0.0001 | 46.6 | 26 | 42 | GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005777; C:peroxisome; IDA:HGNC. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0019166; F:trans-2-enoyl-CoA reductase (NADPH) activity; IEA:EC. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 359 | Q09517 | 316 | LE767_CAEEL Putative steroid dehydrogenase le... | 197 | 0.0001 | 46.6 | 26 | 42 | GO:0045179; C:apical cortex; IDA:WormBase.::GO:0005783; C:endoplasmic reticulum; IDA:WormBase. | | | | | | | | | | GO:0050062; F:long-chain-fatty-acyl-CoA reductase activity; IDA:WormBase.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008209; P:androgen metabolic process; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0008210; P:estrogen metabolic process; IMP:WormBase.::GO:0030540; P:female genitalia development; IMP:UniProtKB.::GO:0040007; P:growth; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0042759; P:long-chain fatty acid biosynthetic process; IDA:WormBase.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0032350; P:regulation of hormone metabolic process; IMP:UniProtKB.::GO:0006694; P:steroid biosynthetic process; IDA:WormBase. | 360 | Q13268 | 258 | DHRS2_HUMAN Dehydrogenase/reductase SDR famil... | 224 | 0.0001 | 46.2 | 25 | 46 | GO:0005739; C:mitochondrion; IDA:UniProtKB.::GO:0005635; C:nuclear envelope; IDA:UniProtKB. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008207; P:C21-steroid hormone metabolic process; NAS:UniProtKB.::GO:0034599; P:cellular response to oxidative stress; IDA:UniProtKB.::GO:0043011; P:myeloid dendritic cell differentiation; IEP:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; NAS:UniProtKB.::GO:0009636; P:response to toxin; IDA:UniProtKB. | 361 | P35320 | 297 | OXIR_STRLI Probable oxidoreductase OS=Strepto... | 137 | 0.0002 | 46.2 | 35 | 45 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | |
