rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
721 | Q91ZR4 | 698 | NEK8_MOUSE Serine/threonine-protein kinase Ne... | 81 | 0.15 | 38.5 | 33 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0072372; C:primary cilium; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 722 | Q9ERH7 | 1192 | HIPK3_MOUSE Homeodomain-interacting protein k... | 197 | 0.16 | 38.9 | 23 | 38 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0016605; C:PML body; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0043508; P:negative regulation of JUN kinase activity; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:UniProtKB.::GO:0043388; P:positive regulation of DNA binding; ISS:UniProtKB. | 723 | Q9LWM4 | 461 | CIPK5_ORYSJ CBL-interacting protein kinase 5 ... | 85 | 0.16 | 38.5 | 34 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 724 | P18431 | 1067 | SGG_DROME Protein kinase shaggy OS=Drosophila... | 86 | 0.16 | 38.9 | 34 | 47 | GO:0045169; C:fusome; IDA:FlyBase.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; NAS:FlyBase. | | | | | | | | | | GO:0008407; P:chaeta morphogenesis; NAS:FlyBase.::GO:0035293; P:chitin-based larval cuticle pattern formation; IMP:FlyBase.::GO:0009649; P:entrainment of circadian clock; IMP:FlyBase.::GO:0003382; P:epithelial cell morphogenesis; IMP:FlyBase.::GO:0090163; P:establishment of epithelial cell planar polarity; IMP:FlyBase.::GO:0046959; P:habituation; IMP:FlyBase.::GO:0007507; P:heart development; NAS:FlyBase.::GO:0045475; P:locomotor rhythm; NAS:FlyBase.::GO:0043508; P:negative regulation of JUN kinase activity; IMP:FlyBase.::GO:0045879; P:negative regulation of smoothened signaling pathway; IDA:FlyBase.::GO:0045886; P:negative regulation of synaptic growth at neuromuscular junction; IMP:FlyBase.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; TAS:FlyBase.::GO:0007219; P:Notch signaling pathway; TAS:FlyBase.::GO:0008355; P:olfactory learning; IMP:FlyBase.::GO:0030707; P:ovarian follicle cell development; IMP:FlyBase.::GO:0045610; P:regulation of hemocyte differentiation; IMP:FlyBase.::GO:0042306; P:regulation of protein import into nucleus; TAS:FlyBase.::GO:0030162; P:regulation of proteolysis; IDA:FlyBase.::GO:0072347; P:response to anesthetic; IMP:FlyBase.::GO:0007367; P:segment polarity determination; IMP:FlyBase.::GO:0035019; P:somatic stem cell maintenance; IMP:FlyBase.::GO:0051124; P:synaptic growth at neuromuscular junction; IMP:FlyBase.::GO:0035309; P:wing and notum subfield formation; IMP:FlyBase.::GO:0016055; P:Wnt receptor signaling pathway; TAS:FlyBase. | 725 | Q9FN94 | 868 | RLK7_ARATH Receptor-like protein kinase At5g5... | 202 | 0.16 | 38.5 | 24 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 726 | P49760 | 499 | CLK2_HUMAN Dual specificity protein kinase CL... | 118 | 0.16 | 38.5 | 28 | 44 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0045721; P:negative regulation of gluconeogenesis; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0043484; P:regulation of RNA splicing; IDA:UniProtKB.::GO:0010212; P:response to ionizing radiation; IMP:UniProtKB. | 727 | Q8VDU5 | 748 | SNRK_MOUSE SNF-related serine/threonine-prote... | 121 | 0.16 | 38.5 | 26 | 45 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | | 728 | Q14680 | 651 | MELK_HUMAN Maternal embryonic leucine zipper ... | 229 | 0.16 | 38.5 | 23 | 36 | GO:0005938; C:cell cortex; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IDA:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IDA:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:UniProtKB.::GO:0030097; P:hemopoiesis; ISS:UniProtKB.::GO:0061351; P:neural precursor cell proliferation; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB. | 729 | Q38870 | 646 | CDPK2_ARATH Calcium-dependent protein kinase ... | 216 | 0.16 | 38.5 | 21 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 730 | Q9NRH2 | 765 | SNRK_HUMAN SNF-related serine/threonine-prote... | 83 | 0.16 | 38.5 | 30 | 48 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0030099; P:myeloid cell differentiation; TAS:UniProtKB. | 731 | Q63553 | 746 | SNRK_RAT SNF-related serine/threonine-protein... | 121 | 0.17 | 38.5 | 26 | 45 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0043523; P:regulation of neuron apoptotic process; TAS:UniProtKB. | 732 | Q91Z96 | 1138 | BMP2K_MOUSE BMP-2-inducible protein kinase OS... | 101 | 0.17 | 38.5 | 29 | 50 | GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019208; F:phosphatase regulator activity; IDA:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030500; P:regulation of bone mineralization; IDA:MGI. | 733 | P53778 | 367 | MK12_HUMAN Mitogen-activated protein kinase 1... | 78 | 0.17 | 38.1 | 35 | 50 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004707; F:MAP kinase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007050; P:cell cycle arrest; TAS:ProtInc.::GO:0006975; P:DNA damage induced protein phosphorylation; TAS:ProtInc.::GO:0007517; P:muscle organ development; TAS:ProtInc.::GO:0045445; P:myoblast differentiation; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 734 | Q01986 | 393 | MP2K1_RAT Dual specificity mitogen-activated ... | 86 | 0.18 | 38.1 | 31 | 49 | GO:0033267; C:axon part; IDA:RGD.::GO:0005938; C:cell cortex; IDA:RGD.::GO:0005829; C:cytosol; TAS:UniProtKB.::GO:0032839; C:dendrite cytoplasm; IDA:RGD.::GO:0005769; C:early endosome; TAS:UniProtKB.::GO:0005925; C:focal adhesion; TAS:UniProtKB.::GO:0005794; C:Golgi apparatus; TAS:UniProtKB.::GO:0005770; C:late endosome; TAS:UniProtKB.::GO:0005739; C:mitochondrion; TAS:UniProtKB.::GO:0005634; C:nucleus; TAS:UniProtKB.::GO:0043204; C:perikaryon; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0004708; F:MAP kinase kinase activity; IDA:RGD.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IDA:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.::GO:0017016; F:Ras GTPase binding; IPI:RGD. | | | | | | | | | | GO:0008283; P:cell proliferation; IDA:RGD.::GO:0048313; P:Golgi inheritance; IMP:RGD.::GO:0032402; P:melanosome transport; IDA:RGD.::GO:0007067; P:mitosis; IDA:RGD.::GO:0034111; P:negative regulation of homotypic cell-cell adhesion; IMP:RGD.::GO:0048812; P:neuron projection morphogenesis; IMP:RGD.::GO:0030335; P:positive regulation of cell migration; IMP:RGD.::GO:0032320; P:positive regulation of Ras GTPase activity; IMP:RGD.::GO:0046579; P:positive regulation of Ras protein signal transduction; IMP:MGI.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IMP:RGD.::GO:2000641; P:regulation of early endosome to late endosome transport; TAS:UniProtKB.::GO:0090170; P:regulation of Golgi inheritance; TAS:UniProtKB.::GO:0032872; P:regulation of stress-activated MAPK cascade; TAS:UniProtKB.::GO:0003056; P:regulation of vascular smooth muscle contraction; IMP:RGD.::GO:0048678; P:response to axon injury; IMP:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IDA:RGD.::GO:0006979; P:response to oxidative stress; IDA:RGD.::GO:0047496; P:vesicle transport along microtubule; IDA:RGD. | 735 | Q63980 | 393 | MP2K1_CRIGR Dual specificity mitogen-activate... | 86 | 0.18 | 38.1 | 31 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 736 | Q91757 | 420 | GSK3B_XENLA Glycogen synthase kinase-3 beta O... | 86 | 0.18 | 38.1 | 34 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IEA:EC. | | | | | | | | | | GO:0060070; P:canonical Wnt receptor signaling pathway; IDA:BHF-UCL.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:BHF-UCL.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW. | 737 | Q5YJC2 | 420 | GSK3B_SPECI Glycogen synthase kinase-3 beta O... | 86 | 0.18 | 38.1 | 34 | 45 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.::GO:0051534; P:negative regulation of NFAT protein import into nucleus; ISS:UniProtKB.::GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0032886; P:regulation of microtubule-based process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 738 | P49841 | 420 | GSK3B_HUMAN Glycogen synthase kinase-3 beta O... | 86 | 0.18 | 38.1 | 34 | 45 | GO:0034747; C:Axin-APC-beta-catenin-GSK3B complex; IDA:BHF-UCL.::GO:0030877; C:beta-catenin destruction complex; IDA:UniProtKB.::GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008013; F:beta-catenin binding; IPI:BHF-UCL.::GO:0051059; F:NF-kappaB binding; IPI:UniProtKB.::GO:0002039; F:p53 binding; IDA:MGI.::GO:0034236; F:protein kinase A catalytic subunit binding; IPI:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0001085; F:RNA polymerase II transcription factor binding; IPI:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IDA:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0060070; P:canonical Wnt receptor signaling pathway; IC:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0001837; P:epithelial to mesenchymal transition; IMP:UniProtKB.::GO:0006983; P:ER overload response; IDA:MGI.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0005977; P:glycogen metabolic process; IDA:BHF-UCL.::GO:0021766; P:hippocampus development; IMP:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; IDA:MGI.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; TAS:UniProtKB.::GO:2000466; P:negative regulation of glycogen (starch) synthase activity; TAS:UniProtKB.::GO:0045719; P:negative regulation of glycogen biosynthetic process; TAS:UniProtKB.::GO:0051534; P:negative regulation of NFAT protein import into nucleus; IMP:UniProtKB.::GO:0032091; P:negative regulation of protein binding; IDA:BHF-UCL.::GO:0031333; P:negative regulation of protein complex assembly; IMP:BHF-UCL.::GO:2000077; P:negative regulation of type B pancreatic cell development; TAS:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0001954; P:positive regulation of cell-matrix adhesion; IMP:BHF-UCL.::GO:0045732; P:positive regulation of protein catabolic process; IC:BHF-UCL.::GO:0031334; P:positive regulation of protein complex assembly; IDA:BHF-UCL.::GO:0046827; P:positive regulation of protein export from nucleus; IDA:MGI.::GO:0032855; P:positive regulation of Rac GTPase activity; IMP:BHF-UCL.::GO:0032886; P:regulation of microtubule-based process; IMP:UniProtKB.::GO:0071109; P:superior temporal gyrus development; IMP:BHF-UCL. | 739 | P31938 | 393 | MP2K1_MOUSE Dual specificity mitogen-activate... | 86 | 0.18 | 38.1 | 31 | 49 | GO:0005829; C:cytosol; TAS:UniProtKB.::GO:0005769; C:early endosome; TAS:UniProtKB.::GO:0005925; C:focal adhesion; TAS:UniProtKB.::GO:0005794; C:Golgi apparatus; TAS:UniProtKB.::GO:0005770; C:late endosome; TAS:UniProtKB.::GO:0005739; C:mitochondrion; TAS:UniProtKB.::GO:0005634; C:nucleus; TAS:UniProtKB.::GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; IMP:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.::GO:0004728; F:receptor signaling protein tyrosine phosphatase activity; IMP:MGI. | | | | | | | | | | GO:0048870; P:cell motility; IMP:MGI.::GO:0030216; P:keratinocyte differentiation; IMP:MGI.::GO:0060711; P:labyrinthine layer development; IMP:MGI.::GO:0060674; P:placenta blood vessel development; IMP:MGI.::GO:0045597; P:positive regulation of cell differentiation; IDA:MGI.::GO:2000641; P:regulation of early endosome to late endosome transport; TAS:UniProtKB.::GO:0090170; P:regulation of Golgi inheritance; TAS:UniProtKB.::GO:0032872; P:regulation of stress-activated MAPK cascade; TAS:UniProtKB. | 740 | Q62925 | 1493 | M3K1_RAT Mitogen-activated protein kinase kin... | 83 | 0.18 | 38.5 | 36 | 48 | GO:0005737; C:cytoplasm; IDA:RGD.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008432; F:JUN kinase binding; IPI:RGD.::GO:0004706; F:JUN kinase kinase kinase activity; IDA:RGD.::GO:0004710; F:MAPK/ERK kinase kinase activity; IDA:RGD.::GO:0051019; F:mitogen-activated protein kinase binding; IPI:RGD.::GO:0031434; F:mitogen-activated protein kinase kinase binding; IPI:RGD.::GO:0046625; F:sphingolipid binding; IPI:RGD.::GO:0004842; F:ubiquitin-protein ligase activity; IMP:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032232; P:negative regulation of actin filament bundle assembly; IDA:RGD.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:RGD.::GO:0043065; P:positive regulation of apoptotic process; IMP:RGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:RGD.::GO:0050434; P:positive regulation of viral transcription; IDA:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0051259; P:protein oligomerization; IDA:RGD.::GO:0000209; P:protein polyubiquitination; IMP:RGD.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IGI:RGD.::GO:0006970; P:response to osmotic stress; IMP:RGD. | 741 | P29678 | 393 | MP2K1_RABIT Dual specificity mitogen-activate... | 86 | 0.18 | 38.1 | 31 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 742 | Q4FCZ5 | 450 | SSN3_GIBMO Serine/threonine-protein kinase SS... | 82 | 0.18 | 38.1 | 29 | 51 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 743 | Q02750 | 393 | MP2K1_HUMAN Dual specificity mitogen-activate... | 86 | 0.19 | 38.1 | 31 | 49 | GO:0005829; C:cytosol; TAS:UniProtKB.::GO:0005769; C:early endosome; TAS:UniProtKB.::GO:0005925; C:focal adhesion; TAS:UniProtKB.::GO:0005794; C:Golgi apparatus; TAS:UniProtKB.::GO:0005770; C:late endosome; TAS:UniProtKB.::GO:0005739; C:mitochondrion; TAS:UniProtKB.::GO:0005634; C:nucleus; TAS:UniProtKB.::GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:Reactome.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007050; P:cell cycle arrest; IMP:BHF-UCL.::GO:0090398; P:cellular senescence; IMP:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:2000641; P:regulation of early endosome to late endosome transport; TAS:UniProtKB.::GO:0090170; P:regulation of Golgi inheritance; TAS:UniProtKB.::GO:0032872; P:regulation of stress-activated MAPK cascade; TAS:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 744 | Q9S7U9 | 363 | M2K2_ARATH Mitogen-activated protein kinase k... | 199 | 0.19 | 38.1 | 25 | 41 | GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009631; P:cold acclimation; IMP:TAIR.::GO:0009814; P:defense response, incompatible interaction; IGI:TAIR.::GO:0009651; P:response to salt stress; IDA:TAIR. | 745 | P25321 | 351 | KAPCA_CRIGR cAMP-dependent protein kinase cat... | 78 | 0.19 | 38.1 | 33 | 49 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; ISS:UniProtKB. | | | | | | | | | | | 746 | Q9WV60 | 420 | GSK3B_MOUSE Glycogen synthase kinase-3 beta O... | 86 | 0.19 | 38.1 | 34 | 45 | GO:0034747; C:Axin-APC-beta-catenin-GSK3B complex; IDA:MGI.::GO:0005829; C:cytosol; IDA:MGI.::GO:0043198; C:dendritic shaft; IDA:MGI.::GO:0030426; C:growth cone; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0030529; C:ribonucleoprotein complex; IDA:MGI.::GO:0005625; C:soluble fraction; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008013; F:beta-catenin binding; IPI:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IDA:MGI. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IMP:MGI.::GO:0007409; P:axonogenesis; IGI:MGI.::GO:0044337; P:canonical Wnt receptor signaling pathway involved in positive regulation of apoptotic process; IMP:BHF-UCL.::GO:0016477; P:cell migration; IGI:MGI.::GO:0008283; P:cell proliferation; TAS:MGI.::GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.::GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0006983; P:ER overload response; IDA:MGI.::GO:0045444; P:fat cell differentiation; IDA:MGI.::GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.::GO:0044027; P:hypermethylation of CpG island; IMP:BHF-UCL.::GO:0007520; P:myoblast fusion; IDA:MGI.::GO:0051534; P:negative regulation of NFAT protein import into nucleus; ISS:UniProtKB.::GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.::GO:0009887; P:organ morphogenesis; IMP:MGI.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:MGI.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:MGI.::GO:0010800; P:positive regulation of peptidyl-threonine phosphorylation; IDA:MGI.::GO:0032092; P:positive regulation of protein binding; IDA:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0006611; P:protein export from nucleus; IDA:MGI.::GO:0035372; P:protein localization to microtubule; IGI:MGI.::GO:0000320; P:re-entry into mitotic cell cycle; IDA:MGI.::GO:0006349; P:regulation of gene expression by genetic imprinting; IMP:BHF-UCL.::GO:0032886; P:regulation of microtubule-based process; IDA:UniProtKB. | 747 | P17612 | 351 | KAPCA_HUMAN cAMP-dependent protein kinase cat... | 78 | 0.19 | 38.1 | 33 | 49 | GO:0005952; C:cAMP-dependent protein kinase complex; NAS:UniProtKB.::GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0004691; F:cAMP-dependent protein kinase activity; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL.::GO:0031625; F:ubiquitin protein ligase binding; IDA:UniProtKB. | | | | | | | | | | GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.::GO:0034199; P:activation of protein kinase A activity; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.::GO:0071333; P:cellular response to glucose stimulus; IDA:UniProtKB.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.::GO:0006094; P:gluconeogenesis; TAS:Reactome.::GO:0007243; P:intracellular protein kinase cascade; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0071158; P:positive regulation of cell cycle arrest; ISS:UniProtKB.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.::GO:0045667; P:regulation of osteoblast differentiation; IDA:UniProtKB.::GO:0061136; P:regulation of proteasomal protein catabolic process; IDA:UniProtKB.::GO:2000810; P:regulation of tight junction assembly; IDA:UniProtKB.::GO:0048240; P:sperm capacitation; ISS:UniProtKB.::GO:0055085; P:transmembrane transport; TAS:Reactome.::GO:0019433; P:triglyceride catabolic process; TAS:Reactome.::GO:0006833; P:water transport; TAS:Reactome. | 748 | Q9C6P3 | 521 | CDPKX_ARATH Calcium-dependent protein kinase ... | 203 | 0.19 | 38.1 | 22 | 40 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 749 | Q8WTQ7 | 553 | GRK7_HUMAN G protein-coupled receptor kinase ... | 97 | 0.19 | 38.1 | 29 | 44 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IEA:EC.::GO:0050254; F:rhodopsin kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0046777; P:protein autophosphorylation; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.::GO:0007601; P:visual perception; IEA:UniProtKB-KW. | 750 | Q8BI55 | 632 | DYRK4_MOUSE Dual specificity tyrosine-phospho... | 83 | 0.19 | 38.5 | 29 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 751 | P36887 | 351 | KAPCA_PIG cAMP-dependent protein kinase catal... | 78 | 0.2 | 38.1 | 33 | 49 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IEA:EC. | | | | | | | | | | |