| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q12577 | 976 | HMDH_GIBFU 3-hydroxy-3-methylglutaryl-coenzym... | 947 | 0 | 1362 | 71 | 84 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro. | 2 | Q0C8L9 | 1048 | HMDH_ASPTN 3-hydroxy-3-methylglutaryl-coenzym... | 1165 | 0 | 887 | 44 | 60 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro. | 3 | Q9Y7D2 | 1048 | HMDH_ASPTE 3-hydroxy-3-methylglutaryl-coenzym... | 1166 | 0 | 885 | 44 | 59 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro. | 4 | P12684 | 1045 | HMDH2_YEAST 3-hydroxy-3-methylglutaryl-coenzy... | 1154 | 0 | 730 | 40 | 56 | GO:0005789; C:endoplasmic reticulum membrane; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005635; C:nuclear envelope; IDA:SGD. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro. | 5 | Q10283 | 1053 | HMDH_SCHPO 3-hydroxy-3-methylglutaryl-coenzym... | 976 | 0 | 723 | 44 | 60 | GO:0005789; C:endoplasmic reticulum membrane; IDA:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; ISS:PomBase. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IDA:PomBase.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:PomBase. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0006696; P:ergosterol biosynthetic process; IMP:PomBase.::GO:0010142; P:farnesyl diphosphate biosynthetic process, mevalonate pathway; ISS:PomBase.::GO:0031505; P:fungal-type cell wall organization; IMP:PomBase. | 6 | Q12649 | 1176 | HMDH_PHYBL 3-hydroxy-3-methylglutaryl-coenzym... | 953 | 0 | 726 | 45 | 63 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro. | 7 | O74164 | 934 | HMDH_CYBJA 3-hydroxy-3-methylglutaryl-coenzym... | 925 | 0 | 698 | 45 | 60 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro. | 8 | P54960 | 856 | HMDH_BLAGE 3-hydroxy-3-methylglutaryl-coenzym... | 77 | 0.71 | 37.7 | 30 | 51 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW. | 9 | O64967 | 628 | HMDH2_GOSHI 3-hydroxy-3-methylglutaryl-coenzy... | 506 | 2e-155 | 486 | 51 | 67 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0042170; C:plastid membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW. | 10 | Q5R6N3 | 888 | HMDH_PONAB 3-hydroxy-3-methylglutaryl-coenzym... | 203 | 0.007 | 44.3 | 22 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro. | 11 | A7Z064 | 888 | HMDH_BOVIN 3-hydroxy-3-methylglutaryl-coenzym... | 203 | 0.014 | 43.5 | 22 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IEA:InterPro.::GO:0016021; C:integral to membrane; IEA:InterPro. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro. | 12 | Q01237 | 887 | HMDH_MOUSE 3-hydroxy-3-methylglutaryl-coenzym... | 227 | 0.008 | 44.3 | 22 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro. | 13 | O64966 | 585 | HMDH1_GOSHI 3-hydroxy-3-methylglutaryl-coenzy... | 465 | 3e-154 | 481 | 54 | 69 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0042170; C:plastid membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW. | 14 | P04035 | 888 | HMDH_HUMAN 3-hydroxy-3-methylglutaryl-coenzym... | 203 | 0.008 | 44.3 | 22 | 39 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome.::GO:0015936; P:coenzyme A metabolic process; IEA:InterPro. | 15 | P20715 | 883 | HMDH_XENLA 3-hydroxy-3-methylglutaryl-coenzym... | 205 | 0.011 | 43.9 | 23 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro. | 16 | Q9XHL5 | 561 | HMDH3_ORYSJ 3-hydroxy-3-methylglutaryl-coenzy... | 416 | 3e-153 | 478 | 57 | 73 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0015936; P:coenzyme A metabolic process; IEA:InterPro. | 17 | P00347 | 887 | HMDH_CRIGR 3-hydroxy-3-methylglutaryl-coenzym... | 236 | 0.005 | 44.7 | 23 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro. | 18 | P34136 | 526 | HMDH2_DICDI 3-hydroxy-3-methylglutaryl-coenzy... | 492 | 2e-152 | 474 | 52 | 68 | GO:0016021; C:integral to membrane; IEA:InterPro. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro. | 19 | P09610 | 887 | HMDH_MESAU 3-hydroxy-3-methylglutaryl-coenzym... | 236 | 0.005 | 45.1 | 23 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro. | 20 | O24594 | 579 | HMDH_MAIZE 3-hydroxy-3-methylglutaryl-coenzym... | 423 | 5e-152 | 475 | 57 | 73 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW. | 21 | Q29512 | 888 | HMDH_RABIT 3-hydroxy-3-methylglutaryl-coenzym... | 227 | 0.006 | 44.7 | 22 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro. | 22 | P29057 | 575 | HMDH1_HEVBR 3-hydroxy-3-methylglutaryl-coenzy... | 416 | 2e-151 | 473 | 56 | 74 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0042170; C:plastid membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW. | 23 | Q03163 | 601 | HMDH_CATRO 3-hydroxy-3-methylglutaryl-coenzym... | 451 | 3e-151 | 474 | 53 | 71 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW. | 24 | P51639 | 887 | HMDH_RAT 3-hydroxy-3-methylglutaryl-coenzyme ... | 236 | 0.006 | 44.7 | 23 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0042282; F:hydroxymethylglutaryl-CoA reductase activity; IDA:RGD.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IDA:RGD. | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0006695; P:cholesterol biosynthetic process; IDA:RGD.::GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0010142; P:farnesyl diphosphate biosynthetic process, mevalonate pathway; TAS:RGD.::GO:0045445; P:myoblast differentiation; IEP:RGD.::GO:0061179; P:negative regulation of insulin secretion involved in cellular response to glucose stimulus; IMP:RGD.::GO:0010664; P:negative regulation of striated muscle cell apoptotic process; IMP:RGD.::GO:0045908; P:negative regulation of vasodilation; IMP:RGD.::GO:0061045; P:negative regulation of wound healing; IMP:RGD.::GO:0010666; P:positive regulation of cardiac muscle cell apoptotic process; IMP:RGD.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:RGD.::GO:0048643; P:positive regulation of skeletal muscle tissue development; IMP:RGD.::GO:0048661; P:positive regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0032874; P:positive regulation of stress-activated MAPK cascade; IMP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0007584; P:response to nutrient; IEP:RGD.::GO:0006743; P:ubiquinone metabolic process; IMP:RGD. | 25 | Q01559 | 604 | HMDH_NICSY 3-hydroxy-3-methylglutaryl-coenzym... | 425 | 4e-151 | 474 | 55 | 73 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW. | 26 | Q1W675 | 885 | HMDH_PIG 3-hydroxy-3-methylglutaryl-coenzyme ... | 203 | 0.016 | 43.1 | 22 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro. | 27 | Q9XEL8 | 604 | HMDH2_CAPAN 3-hydroxy-3-methylglutaryl-coenzy... | 425 | 4e-150 | 471 | 54 | 73 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW. | 28 | Q41438 | 574 | HMDH3_SOLTU 3-hydroxy-3-methylglutaryl-coenzy... | 462 | 8e-150 | 469 | 52 | 70 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW. | 29 | P48022 | 602 | HMDH2_SOLLC 3-hydroxy-3-methylglutaryl-coenzy... | 425 | 1e-149 | 470 | 55 | 73 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW. | 30 | P48020 | 596 | HMDH1_SOLTU 3-hydroxy-3-methylglutaryl-coenzy... | 468 | 2e-149 | 469 | 51 | 69 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW. | 31 | P34135 | 552 | HMDH1_DICDI 3-hydroxy-3-methylglutaryl-coenzy... | 435 | 2e-148 | 465 | 54 | 72 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:InterPro. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro. |
