| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q91819 | 408 | AURAB_XENLA Aurora kinase A-B OS=Xenopus laev... | 102 | 0.00000001 | 60.1 | 36 | 50 | GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005876; C:spindle microtubule; ISS:UniProtKB.::GO:0000922; C:spindle pole; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019894; F:kinesin binding; ISS:UniProtKB.::GO:0008017; F:microtubule binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0018105; P:peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0090307; P:spindle assembly involved in mitosis; ISS:UniProtKB. | 32 | P59241 | 397 | AURKA_RAT Aurora kinase A OS=Rattus norvegicu... | 100 | 0.00000002 | 60.1 | 37 | 51 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0032355; P:response to estradiol stimulus; IEP:RGD. | 33 | P43637 | 560 | TOS3_YEAST Serine/threonine-protein kinase TO... | 99 | 6.3 | 33.1 | 28 | 44 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IMP:SGD.::GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 34 | A6ZU08 | 560 | TOS3_YEAS7 Serine/threonine-protein kinase TO... | 99 | 6.3 | 33.1 | 28 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 35 | P97477 | 395 | AURKA_MOUSE Aurora kinase A OS=Mus musculus (... | 100 | 0.00000005 | 58.5 | 37 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IPI:MGI. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 36 | Q9XF67 | 491 | PDPK1_ARATH 3-phosphoinositide-dependent prot... | 173 | 0.00000005 | 58.5 | 28 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; IGI:TAIR.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0070300; F:phosphatidic acid binding; IDA:UniProtKB.::GO:0035091; F:phosphatidylinositol binding; IDA:TAIR.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0045860; P:positive regulation of protein kinase activity; IDA:TAIR.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB. | 37 | Q54PB4 | 481 | MYLKE_DICDI Probable myosin light chain kinas... | 131 | 0.00000005 | 58.5 | 31 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; ISS:dictyBase.::GO:0004687; F:myosin light chain kinase activity; IEA:EC. | | | | | | | | | | GO:0007165; P:signal transduction; ISS:dictyBase. | 38 | Q99KY4 | 1305 | GAK_MOUSE Cyclin-G-associated kinase OS=Mus m... | 134 | 0.022 | 41.2 | 24 | 45 | GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW. | 39 | P97874 | 1305 | GAK_RAT Cyclin-G-associated kinase OS=Rattus ... | 141 | 0.018 | 41.2 | 25 | 43 | GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030332; F:cyclin binding; IDA:RGD.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW. | 40 | Q9QUK0 | 568 | CDKL2_MOUSE Cyclin-dependent kinase-like 2 OS... | 185 | 0.00000008 | 58.2 | 28 | 44 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 41 | Q6CWQ4 | 361 | IPL1_KLULA Spindle assembly checkpoint kinase... | 103 | 5.1 | 33.1 | 29 | 44 | GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW. | 42 | Q91820 | 407 | AURAA_XENLA Aurora kinase A-A OS=Xenopus laev... | 102 | 0.00000008 | 57.8 | 35 | 49 | GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005876; C:spindle microtubule; IDA:UniProtKB.::GO:0000922; C:spindle pole; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019894; F:kinesin binding; IPI:UniProtKB.::GO:0008017; F:microtubule binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0018105; P:peptidyl-serine phosphorylation; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IMP:UniProtKB.::GO:0090307; P:spindle assembly involved in mitosis; IMP:UniProtKB. | 43 | P54744 | 622 | PKNB_MYCLE Serine/threonine-protein kinase pk... | 93 | 0.0000001 | 57.4 | 41 | 53 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 44 | Q18846 | 772 | KS6A2_CAEEL Putative ribosomal protein S6 kin... | 97 | 0.86 | 35.8 | 31 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.::GO:0002119; P:nematode larval development; IMP:WormBase. | 45 | Q8BGW6 | 398 | ST32A_MOUSE Serine/threonine-protein kinase 3... | 108 | 0.0000002 | 56.6 | 32 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 46 | O54992 | 473 | MAPK5_MOUSE MAP kinase-activated protein kina... | 198 | 0.0000002 | 57 | 24 | 38 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051019; F:mitogen-activated protein kinase binding; IPI:UniProtKB.::GO:0002039; F:p53 binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0032007; P:negative regulation of TOR signaling cascade; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0007265; P:Ras protein signal transduction; IMP:UniProtKB.::GO:0006417; P:regulation of translation; ISS:UniProtKB.::GO:0090400; P:stress-induced premature senescence; IMP:UniProtKB. | 47 | Q8AYG3 | 982 | TTK_DANRE Dual specificity protein kinase Ttk... | 183 | 0.0000002 | 57.4 | 27 | 39 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0009790; P:embryo development; IMP:UniProtKB.::GO:0007093; P:mitotic cell cycle checkpoint; IMP:UniProtKB.::GO:0042246; P:tissue regeneration; IMP:UniProtKB. | 48 | Q64261 | 326 | CDK6_MOUSE Cyclin-dependent kinase 6 OS=Mus m... | 180 | 0.0000002 | 56.2 | 30 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0002244; P:hemopoietic progenitor cell differentiation; IMP:MGI.::GO:0060218; P:hemopoietic stem cell differentiation; IMP:MGI.::GO:0007219; P:Notch signaling pathway; IDA:MGI.::GO:0010628; P:positive regulation of gene expression; IDA:MGI.::GO:0033077; P:T cell differentiation in thymus; IMP:MGI. | 49 | P0A5S4 | 626 | PKNB_MYCTU Serine/threonine-protein kinase pk... | 146 | 1.5 | 35 | 23 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030145; F:manganese ion binding; IDA:MTBBASE.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MTBBASE.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MTBBASE. | | | | | | | | | | GO:0040007; P:growth; IMP:MTBBASE.::GO:0043086; P:negative regulation of catalytic activity; IDA:MTBBASE.::GO:0032091; P:negative regulation of protein binding; IDA:MTBBASE.::GO:0043085; P:positive regulation of catalytic activity; IDA:MTBBASE.::GO:0043388; P:positive regulation of DNA binding; IDA:MTBBASE.::GO:0046777; P:protein autophosphorylation; IDA:MTBBASE.::GO:0008360; P:regulation of cell shape; IMP:MTBBASE.::GO:0051338; P:regulation of transferase activity; IDA:MTBBASE.::GO:0052572; P:response to host immune response; IDA:MTBBASE. | 50 | P0A5S5 | 626 | PKNB_MYCBO Serine/threonine-protein kinase pk... | 146 | 1.5 | 35 | 23 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 51 | P32562 | 705 | CDC5_YEAST Cell cycle serine/threonine-protei... | 188 | 0.0000002 | 57 | 29 | 43 | GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0000922; C:spindle pole; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0010696; P:positive regulation of spindle pole body separation; IMP:SGD.::GO:0000712; P:resolution of meiotic recombination intermediates; IMP:SGD.::GO:0090306; P:spindle assembly involved in meiosis; IMP:SGD.::GO:0070194; P:synaptonemal complex disassembly; IGI:SGD. | 52 | O14976 | 1311 | GAK_HUMAN Cyclin-G-associated kinase OS=Homo ... | 134 | 0.003 | 43.9 | 24 | 46 | GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW. | 53 | Q8WU08 | 396 | ST32A_HUMAN Serine/threonine-protein kinase 3... | 79 | 2.6 | 33.9 | 30 | 51 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 54 | Q5XIT0 | 507 | CDKL2_RAT Cyclin-dependent kinase-like 2 OS=R... | 185 | 0.0000003 | 56.6 | 28 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 55 | P32865 | 700 | GPRK1_DROME G protein-coupled receptor kinase... | 250 | 0.0000003 | 56.6 | 27 | 37 | | | | | | | | | | | GO:0005524; F:ATP binding; IMP:FlyBase.::GO:0001664; F:G-protein coupled receptor binding; IPI:FlyBase.::GO:0004703; F:G-protein coupled receptor kinase activity; IEA:EC.::GO:0035091; F:phosphatidylinositol binding; IDA:FlyBase.::GO:0050254; F:rhodopsin kinase activity; IMP:FlyBase. | | | | | | | | | | GO:0007474; P:imaginal disc-derived wing vein specification; IGI:FlyBase.::GO:0016060; P:metarhodopsin inactivation; IMP:FlyBase.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro. | 56 | Q8G6P9 | 690 | PKNB_BIFLO Probable serine/threonine-protein ... | 148 | 0.001 | 45.1 | 25 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 57 | Q8IW41 | 473 | MAPK5_HUMAN MAP kinase-activated protein kina... | 198 | 0.0000003 | 55.8 | 24 | 38 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; TAS:ProtInc.::GO:0002039; F:p53 binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0032007; P:negative regulation of TOR signaling cascade; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0007265; P:Ras protein signal transduction; IDA:UniProtKB.::GO:0006417; P:regulation of translation; IDA:UniProtKB.::GO:0090400; P:stress-induced premature senescence; IDA:UniProtKB. | 58 | Q4V3C8 | 486 | PDPK2_ARATH 3-phosphoinositide-dependent prot... | 173 | 0.0000003 | 55.8 | 28 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 59 | Q00534 | 326 | CDK6_HUMAN Cyclin-dependent kinase 6 OS=Homo ... | 180 | 0.0000004 | 55.5 | 29 | 41 | GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IDA:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0001726; C:ruffle; IDA:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:BHF-UCL.::GO:0030332; F:cyclin binding; IPI:BHF-UCL.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:BHF-UCL. | | | | | | | | | | GO:0014002; P:astrocyte development; ISS:UniProtKB.::GO:0007050; P:cell cycle arrest; TAS:UniProtKB.::GO:0043697; P:cell dedifferentiation; IMP:BHF-UCL.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0021542; P:dentate gyrus development; ISS:UniProtKB.::GO:0000080; P:G1 phase of mitotic cell cycle; IEP:BHF-UCL.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:UniProtKB.::GO:0048699; P:generation of neurons; ISS:UniProtKB.::GO:0021670; P:lateral ventricle development; ISS:UniProtKB.::GO:2000773; P:negative regulation of cellular senescence; IDA:UniProtKB.::GO:0050680; P:negative regulation of epithelial cell proliferation; IMP:BHF-UCL.::GO:0045638; P:negative regulation of myeloid cell differentiation; IDA:UniProtKB.::GO:0045668; P:negative regulation of osteoblast differentiation; IDA:BHF-UCL.::GO:0001954; P:positive regulation of cell-matrix adhesion; IDA:BHF-UCL.::GO:0048146; P:positive regulation of fibroblast proliferation; IMP:BHF-UCL.::GO:2000145; P:regulation of cell motility; ISS:UniProtKB.::GO:0045646; P:regulation of erythrocyte differentiation; IMP:BHF-UCL.::GO:0009615; P:response to virus; IEP:UniProtKB.::GO:0003323; P:type B pancreatic cell development; IDA:UniProtKB. | 60 | Q9Z335 | 417 | SBK1_RAT Serine/threonine-protein kinase SBK1... | 103 | 0.0000004 | 55.8 | 33 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD. | | | | | | | | | | GO:0007420; P:brain development; IEP:RGD.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:RGD.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:RGD. | 61 | Q8QZX0 | 417 | SBK1_MOUSE Serine/threonine-protein kinase SB... | 103 | 0.0000004 | 55.5 | 33 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | |
