| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
121 | Q5BBL3 | 848 | STE20_EMENI Serine/threonine-protein kinase s... | 81 | 0.5 | 38.1 | 27 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019236; P:response to pheromone; IEA:UniProtKB-KW. | 122 | Q8MY85 | 887 | FGFR2_DUGJA Fibroblast growth factor receptor... | 201 | 0.51 | 38.1 | 26 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 123 | P05130 | 679 | KPC1_DROME Protein kinase C, brain isozyme OS... | 175 | 0.52 | 38.1 | 26 | 37 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 124 | Q9YI66 | 874 | TYRO3_DANRE Tyrosine-protein kinase receptor ... | 64 | 0.52 | 38.1 | 34 | 52 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 125 | Q5R8Z4 | 681 | PAK6_PONAB Serine/threonine-protein kinase PA... | 73 | 0.54 | 38.1 | 30 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 126 | Q9UEW8 | 545 | STK39_HUMAN STE20/SPS1-related proline-alanin... | 72 | 0.55 | 37.7 | 31 | 54 | GO:0005737; C:cytoplasm; NAS:UniProtKB.::GO:0005634; C:nucleus; NAS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0004702; F:receptor signaling protein serine/threonine kinase activity; NAS:UniProtKB. | | | | | | | | | | GO:0006950; P:response to stress; NAS:UniProtKB. | 127 | Q9NQU5 | 681 | PAK6_HUMAN Serine/threonine-protein kinase PA... | 73 | 0.59 | 37.7 | 30 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:UniProtKB.::GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; TAS:UniProtKB. | 128 | P53349 | 1493 | M3K1_MOUSE Mitogen-activated protein kinase k... | 79 | 0.61 | 38.1 | 32 | 48 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; IDA:BHF-UCL. | 129 | Q62925 | 1493 | M3K1_RAT Mitogen-activated protein kinase kin... | 79 | 0.62 | 38.1 | 32 | 48 | GO:0005737; C:cytoplasm; IDA:RGD.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008432; F:JUN kinase binding; IPI:RGD.::GO:0004706; F:JUN kinase kinase kinase activity; IDA:RGD.::GO:0004710; F:MAPK/ERK kinase kinase activity; IDA:RGD.::GO:0051019; F:mitogen-activated protein kinase binding; IPI:RGD.::GO:0031434; F:mitogen-activated protein kinase kinase binding; IPI:RGD.::GO:0046625; F:sphingolipid binding; IPI:RGD.::GO:0004842; F:ubiquitin-protein ligase activity; IMP:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032232; P:negative regulation of actin filament bundle assembly; IDA:RGD.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:RGD.::GO:0043065; P:positive regulation of apoptotic process; IMP:RGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:RGD.::GO:0050434; P:positive regulation of viral transcription; IDA:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0051259; P:protein oligomerization; IDA:RGD.::GO:0000209; P:protein polyubiquitination; IMP:RGD.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IGI:RGD.::GO:0006970; P:response to osmotic stress; IMP:RGD. | 130 | Q54P47 | 1335 | NDRC_DICDI Probable serine/threonine-protein ... | 100 | 0.64 | 38.1 | 29 | 46 | GO:0005634; C:nucleus; ISS:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 131 | Q3ULB5 | 682 | PAK6_MOUSE Serine/threonine-protein kinase PA... | 73 | 0.65 | 37.7 | 29 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 132 | P50527 | 658 | STE20_SCHPO Serine/threonine-protein kinase s... | 76 | 0.67 | 37.7 | 28 | 50 | GO:0071521; C:Cdc42 GTPase complex; TAS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase. | | | | | | | | | | GO:0032488; P:Cdc42 protein signal transduction; IGI:PomBase.::GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; TAS:PomBase.::GO:0061161; P:positive regulation of establishment of bipolar cell polarity regulating cell shape; IGI:PomBase.::GO:0071775; P:regulation of cell cycle cytokinesis; IMP:PomBase.::GO:0070507; P:regulation of microtubule cytoskeleton organization; IGI:PomBase. | 133 | Q9N3Z3 | 503 | CHK1_CAEEL Serine/threonine-protein kinase ch... | 190 | 0.68 | 37.7 | 22 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0007049; P:cell cycle; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW. | 134 | Q62407 | 3262 | SPEG_MOUSE Striated muscle-specific serine/th... | 33 | 0.71 | 37.7 | 42 | 67 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW. | 135 | Q13233 | 1512 | M3K1_HUMAN Mitogen-activated protein kinase k... | 79 | 0.71 | 37.7 | 32 | 48 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome. | 136 | Q6DT37 | 1551 | MRCKG_HUMAN Serine/threonine-protein kinase M... | 138 | 0.72 | 37.7 | 29 | 45 | GO:0031252; C:cell leading edge; IDA:UniProtKB.::GO:0005813; C:centrosome; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 137 | P57760 | 305 | STK16_RAT Serine/threonine-protein kinase 16 ... | 89 | 0.72 | 37 | 33 | 49 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:RGD. | | | | | | | | | | GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD. | 138 | Q9ST27 | 907 | PHOT2_ORYSJ Phototropin-2 OS=Oryza sativa sub... | 76 | 0.73 | 37.7 | 33 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0009882; F:blue light photoreceptor activity; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0018298; P:protein-chromophore linkage; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. | 139 | Q04912 | 1400 | RON_HUMAN Macrophage-stimulating protein rece... | 62 | 0.76 | 37.7 | 34 | 58 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0005011; F:macrophage colony-stimulating factor receptor activity; TAS:ProtInc. | | | | | | | | | | GO:0006928; P:cellular component movement; TAS:ProtInc.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:InterPro.::GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.::GO:0043406; P:positive regulation of MAP kinase activity; IDA:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IDA:UniProtKB.::GO:0009615; P:response to virus; IDA:UniProtKB.::GO:0007338; P:single fertilization; TAS:ProtInc.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro. | 140 | Q08942 | 431 | NRKA_TRYBB Putative serine/threonine-protein ... | 73 | 0.76 | 37.4 | 27 | 52 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 141 | P92199 | 1173 | ROCK_CAEEL Rho-associated protein kinase let-... | 138 | 0.81 | 37.7 | 28 | 46 | GO:0005913; C:cell-cell adherens junction; IDA:WormBase.::GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0043292; C:contractile fiber; IDA:WormBase.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; IMP:WormBase.::GO:0040002; P:collagen and cuticulin-based cuticle development; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0010172; P:embryonic body morphogenesis; IMP:WormBase.::GO:0001703; P:gastrulation with mouth forming first; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0048477; P:oogenesis; IEA:UniProtKB-KW.::GO:0008360; P:regulation of cell shape; IMP:WormBase.::GO:0007266; P:Rho protein signal transduction; TAS:WormBase. | 142 | Q9TTK0 | 566 | CDKL2_RABIT Cyclin-dependent kinase-like 2 OS... | 78 | 0.83 | 37.4 | 28 | 55 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 143 | Q9P286 | 719 | PAK7_HUMAN Serine/threonine-protein kinase PA... | 73 | 0.9 | 37.4 | 30 | 49 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:UniProtKB.::GO:0016049; P:cell growth; TAS:UniProtKB.::GO:0016477; P:cell migration; TAS:UniProtKB.::GO:0008283; P:cell proliferation; TAS:UniProtKB.::GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.::GO:0007165; P:signal transduction; TAS:UniProtKB. | 144 | P57097 | 994 | MERTK_RAT Tyrosine-protein kinase Mer OS=Ratt... | 182 | 0.9 | 37.4 | 24 | 38 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0001750; C:photoreceptor outer segment; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; NAS:RGD. | | | | | | | | | | | 145 | O73791 | 1116 | TIE2_DANRE Tyrosine-protein kinase receptor T... | 149 | 0.92 | 37.4 | 24 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro. | 146 | Q15772 | 3267 | SPEG_HUMAN Striated muscle preferentially exp... | 127 | 0.94 | 37.4 | 24 | 39 | GO:0005634; C:nucleus; TAS:ProtInc. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007517; P:muscle organ development; TAS:ProtInc.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc. | 147 | Q922R0 | 355 | PRKX_MOUSE cAMP-dependent protein kinase cata... | 140 | 1 | 37 | 26 | 46 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0001525; P:angiogenesis; IMP:UniProtKB.::GO:0031589; P:cell-substrate adhesion; ISS:UniProtKB.::GO:0043542; P:endothelial cell migration; ISS:UniProtKB.::GO:0001935; P:endothelial cell proliferation; IMP:UniProtKB.::GO:0060562; P:epithelial tube morphogenesis; ISS:UniProtKB.::GO:0060993; P:kidney morphogenesis; ISS:UniProtKB.::GO:0030099; P:myeloid cell differentiation; ISS:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.::GO:2000696; P:regulation of epithelial cell differentiation involved in kidney development; ISS:UniProtKB. | 148 | Q91ZR4 | 698 | NEK8_MOUSE Serine/threonine-protein kinase Ne... | 71 | 1.1 | 37 | 27 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0072372; C:primary cilium; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 149 | O99010 | 130 | RK12_PROWI 50S ribosomal protein L12, plastid... | 78 | 1.1 | 35 | 31 | 50 | GO:0009536; C:plastid; IEA:UniProtKB-SubCell.::GO:0005840; C:ribosome; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003735; F:structural constituent of ribosome; IEA:InterPro. | | | | | | | | | | GO:0006412; P:translation; IEA:InterPro. | 150 | Q86SG6 | 692 | NEK8_HUMAN Serine/threonine-protein kinase Ne... | 71 | 1.1 | 37 | 27 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0072372; C:primary cilium; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 151 | Q80YE4 | 1365 | LMTK1_MOUSE Serine/threonine-protein kinase L... | 105 | 1.3 | 37 | 29 | 36 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IDA:MGI.::GO:0046777; P:protein autophosphorylation; IDA:MGI. |
