| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
811 | Q6UW02 | 462 | CP20A_HUMAN Cytochrome P450 20A1 OS=Homo sapi... | 245 | 0.01 | 41.6 | 22 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 812 | Q9V399 | 503 | CP303_DROME Probable cytochrome P450 303a1 OS... | 162 | 0.011 | 41.6 | 24 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0007423; P:sensory organ development; IMP:FlyBase. | 813 | Q9ZV28 | 493 | C7104_ARATH Cytochrome P450 710A1 OS=Arabidop... | 167 | 0.012 | 41.6 | 22 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000249; F:C-22 sterol desaturase activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 814 | P93596 | 453 | CP51_WHEAT Obtusifoliol 14-alpha demethylase ... | 401 | 0.012 | 41.6 | 21 | 38 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 815 | O64698 | 499 | C7102_ARATH Cytochrome P450 710A2 OS=Arabidop... | 168 | 0.013 | 41.2 | 22 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000249; F:C-22 sterol desaturase activity; IDA:TAIR.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 816 | Q01741 | 258 | CP1A2_CHICK Cytochrome P450 1A2 OS=Gallus gal... | 164 | 0.014 | 40.8 | 26 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 817 | P85191 | 155 | CP450_HELAN Cytochrome P450 OS=Helianthus ann... | 143 | 0.015 | 39.7 | 24 | 41 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 818 | Q28827 | 445 | CP11A_RABIT Cholesterol side-chain cleavage e... | 71 | 0.016 | 41.2 | 32 | 46 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008386; F:cholesterol monooxygenase (side-chain-cleaving) activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW. | 819 | P70091 | 522 | CP19A_ORENI Cytochrome P450 19A1 OS=Oreochrom... | 323 | 0.019 | 40.8 | 23 | 39 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 820 | Q9GQM9 | 503 | CP6L1_BLAGE Cytochrome P450 6l1 OS=Blattella ... | 210 | 0.023 | 40.4 | 21 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 821 | Q9V979 | 488 | CP6U1_DROME Probable cytochrome P450 6u1 OS=D... | 206 | 0.031 | 40 | 24 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 822 | P22680 | 504 | CP7A1_HUMAN Cholesterol 7-alpha-monooxygenase... | 275 | 0.035 | 40 | 20 | 38 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; ISS:UniProtKB. | | | | | | | | | | GO:0008123; F:cholesterol 7-alpha-monooxygenase activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0006699; P:bile acid biosynthetic process; IDA:UniProtKB.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0071397; P:cellular response to cholesterol; ISS:UniProtKB.::GO:0071333; P:cellular response to glucose stimulus; IDA:UniProtKB.::GO:0006707; P:cholesterol catabolic process; ISS:UniProtKB.::GO:0042632; P:cholesterol homeostasis; ISS:UniProtKB.::GO:0070857; P:regulation of bile acid biosynthetic process; IDA:UniProtKB.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 823 | Q6P7D4 | 462 | CP20A_RAT Cytochrome P450 20A1 OS=Rattus norv... | 172 | 0.053 | 39.3 | 23 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 824 | Q9V3S0 | 556 | CP4G1_DROME Cytochrome P450 4g1 OS=Drosophila... | 171 | 0.055 | 39.3 | 22 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0006629; P:lipid metabolic process; IMP:FlyBase. | 825 | P33271 | 405 | CPXK_SACEN Cytochrome P450 107B1 OS=Saccharop... | 196 | 0.064 | 38.9 | 24 | 37 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 826 | Q86A22 | 494 | C515A_DICDI Probable cytochrome P450 515A1 OS... | 173 | 0.081 | 38.9 | 23 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 827 | O64697 | 495 | C7101_ARATH Cytochrome P450 710A1 OS=Arabidop... | 184 | 0.29 | 37 | 22 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000249; F:C-22 sterol desaturase activity; IDA:TAIR.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 828 | P37119 | 365 | C71A3_SOLME Cytochrome P450 71A3 OS=Solanum m... | 213 | 0.34 | 36.6 | 22 | 42 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 829 | O33180 | 434 | CP144_MYCTU Cytochrome P450 144 OS=Mycobacter... | 180 | 0.38 | 36.6 | 24 | 36 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 830 | P24466 | 422 | CPXC_RHIRD Cytochrome P450-pinF1, plant-induc... | 208 | 0.68 | 35.8 | 20 | 38 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 831 | Q40778 | 473 | C74A2_PARAR Allene oxide synthase OS=Partheni... | 148 | 0.83 | 35.4 | 20 | 41 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0047987; F:hydroperoxide dehydratase activity; IEA:EC.::GO:0004497; F:monooxygenase activity; IEA:InterPro.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0031408; P:oxylipin biosynthetic process; IEA:UniProtKB-KW. | 832 | Q16647 | 500 | PTGIS_HUMAN Prostacyclin synthase OS=Homo sap... | 186 | 0.86 | 35.4 | 24 | 39 | GO:0005901; C:caveola; IDA:UniProtKB.::GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; NAS:UniProtKB.::GO:0004497; F:monooxygenase activity; IEA:InterPro.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.::GO:0008116; F:prostaglandin-I synthase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0071456; P:cellular response to hypoxia; IDA:UniProtKB.::GO:0071347; P:cellular response to interleukin-1; IEP:UniProtKB.::GO:0071354; P:cellular response to interleukin-6; IEP:UniProtKB.::GO:0050728; P:negative regulation of inflammatory response; IDA:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0045019; P:negative regulation of nitric oxide biosynthetic process; IDA:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.::GO:0035360; P:positive regulation of peroxisome proliferator activated receptor signaling pathway; IDA:UniProtKB.::GO:0001516; P:prostaglandin biosynthetic process; IDA:UniProtKB.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 833 | C4B644 | 403 | CPVDH_PSEAH Vitamin D(3) 25-hydroxylase OS=au... | 215 | 1.1 | 35 | 22 | 37 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047749; F:cholestanetriol 26-monooxygenase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 834 | Q64505 | 503 | CP7A1_MOUSE Cholesterol 7-alpha-monooxygenase... | 276 | 1.3 | 35 | 20 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; ISS:UniProtKB. | | | | | | | | | | GO:0008123; F:cholesterol 7-alpha-monooxygenase activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0006699; P:bile acid biosynthetic process; ISS:UniProtKB.::GO:0071397; P:cellular response to cholesterol; ISS:UniProtKB.::GO:0071333; P:cellular response to glucose stimulus; ISS:UniProtKB.::GO:0006707; P:cholesterol catabolic process; ISS:UniProtKB.::GO:0042632; P:cholesterol homeostasis; ISS:UniProtKB.::GO:0070859; P:positive regulation of bile acid biosynthetic process; TAS:BHF-UCL. | 835 | P46634 | 504 | CP7A1_CRIGR Cholesterol 7-alpha-monooxygenase... | 274 | 1.3 | 35 | 19 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; ISS:UniProtKB. | | | | | | | | | | GO:0008123; F:cholesterol 7-alpha-monooxygenase activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0006699; P:bile acid biosynthetic process; ISS:UniProtKB.::GO:0071397; P:cellular response to cholesterol; ISS:UniProtKB.::GO:0071333; P:cellular response to glucose stimulus; ISS:UniProtKB.::GO:0006707; P:cholesterol catabolic process; ISS:UniProtKB.::GO:0042632; P:cholesterol homeostasis; ISS:UniProtKB.::GO:0070857; P:regulation of bile acid biosynthetic process; ISS:UniProtKB. | 836 | Q1ZXC4 | 500 | C5142_DICDI Probable cytochrome P450 514A2 OS... | 135 | 1.3 | 35 | 21 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 837 | P53554 | 395 | BIOI_BACSU Biotin biosynthesis cytochrome P45... | 77 | 1.7 | 34.7 | 32 | 52 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0009102; P:biotin biosynthetic process; IDA:UniProtKB. | 838 | Q18CD6 | 493 | SYE_CLOD6 Glutamate--tRNA ligase OS=Clostridi... | 61 | 2.1 | 34.3 | 39 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004818; F:glutamate-tRNA ligase activity; IEA:EC. | | | | | | | | | | GO:0006424; P:glutamyl-tRNA aminoacylation; IEA:InterPro. | 839 | Q7YRB2 | 501 | CP8B1_PIG 5-beta-cholestane-3-alpha,7-alpha-d... | 200 | 4.8 | 33.1 | 22 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0033779; F:5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | |
