| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P32948 | 549 | LIP4_CANRU Lipase 4 OS=Candida rugosa (Yeast)... | 537 | 1e-42 | 165 | 28 | 45 | | | | | | | | | | | GO:0050253; F:retinyl-palmitate esterase activity; IEA:EC.::GO:0004806; F:triglyceride lipase activity; IEA:EC. | | | | | | | | | | GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 2 | P32946 | 548 | LIP2_CANRU Lipase 2 OS=Candida rugosa (Yeast)... | 538 | 4e-41 | 160 | 28 | 43 | | | | | | | | | | | GO:0050253; F:retinyl-palmitate esterase activity; IEA:EC.::GO:0004806; F:triglyceride lipase activity; IEA:EC. | | | | | | | | | | GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 3 | O62760 | 602 | CHLE_FELCA Cholinesterase OS=Felis catus (Cat... | 560 | 2e-38 | 153 | 30 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0003990; F:acetylcholinesterase activity; ISS:UniProtKB.::GO:0004091; F:carboxylesterase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 4 | O62761 | 602 | CHLE_PANTT Cholinesterase OS=Panthera tigris ... | 560 | 2e-38 | 153 | 30 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0003990; F:acetylcholinesterase activity; ISS:UniProtKB.::GO:0004091; F:carboxylesterase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 5 | P06276 | 602 | CHLE_HUMAN Cholinesterase OS=Homo sapiens (Hu... | 607 | 7e-38 | 151 | 29 | 42 | GO:0005788; C:endoplasmic reticulum lumen; IBA:RefGenome.::GO:0005615; C:extracellular space; IBA:RefGenome.::GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0003990; F:acetylcholinesterase activity; ISS:UniProtKB.::GO:0001540; F:beta-amyloid binding; NAS:UniProtKB.::GO:0004091; F:carboxylesterase activity; IBA:RefGenome.::GO:0019899; F:enzyme binding; NAS:UniProtKB. | | | | | | | | | | GO:0019695; P:choline metabolic process; IBA:RefGenome.::GO:0050783; P:cocaine metabolic process; TAS:UniProtKB.::GO:0007271; P:synaptic transmission, cholinergic; IBA:RefGenome. | 6 | P21927 | 581 | CHLE_RABIT Cholinesterase OS=Oryctolagus cuni... | 551 | 1e-37 | 150 | 29 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0003990; F:acetylcholinesterase activity; ISS:UniProtKB.::GO:0004091; F:carboxylesterase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 7 | P32947 | 549 | LIP3_CANRU Lipase 3 OS=Candida rugosa (Yeast)... | 384 | 1e-37 | 150 | 31 | 46 | | | | | | | | | | | GO:0050253; F:retinyl-palmitate esterase activity; IEA:EC.::GO:0004806; F:triglyceride lipase activity; IEA:EC. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 8 | P20261 | 549 | LIP1_CANRU Lipase 1 OS=Candida rugosa (Yeast)... | 384 | 2e-37 | 149 | 31 | 46 | | | | | | | | | | | GO:0050253; F:retinyl-palmitate esterase activity; IEA:EC.::GO:0004806; F:triglyceride lipase activity; IEA:EC. | | | | | | | | | | GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 9 | P22303 | 614 | ACES_HUMAN Acetylcholinesterase OS=Homo sapie... | 564 | 2e-37 | 150 | 28 | 44 | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0030424; C:axon; IBA:RefGenome.::GO:0005605; C:basal lamina; NAS:HGNC.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0009986; C:cell surface; IBA:RefGenome.::GO:0030425; C:dendrite; IBA:RefGenome.::GO:0005788; C:endoplasmic reticulum lumen; IBA:RefGenome.::GO:0005615; C:extracellular space; IBA:RefGenome.::GO:0005794; C:Golgi apparatus; IDA:HGNC.::GO:0031594; C:neuromuscular junction; IBA:RefGenome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IDA:HGNC.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0045211; C:postsynaptic membrane; IBA:RefGenome.::GO:0042734; C:presynaptic membrane; IBA:RefGenome.::GO:0043083; C:synaptic cleft; NAS:GOC. | | | | | | | | | | GO:0042166; F:acetylcholine binding; NAS:UniProtKB.::GO:0003990; F:acetylcholinesterase activity; IMP:UniProtKB.::GO:0001540; F:beta-amyloid binding; TAS:UniProtKB.::GO:0004091; F:carboxylesterase activity; IBA:RefGenome.::GO:0005518; F:collagen binding; IDA:HGNC.::GO:0043236; F:laminin binding; IDA:BHF-UCL.::GO:0042803; F:protein homodimerization activity; NAS:UniProtKB.::GO:0017171; F:serine hydrolase activity; IDA:HGNC. | | | | | | | | | | GO:0001507; P:acetylcholine catabolic process in synaptic cleft; NAS:UniProtKB.::GO:0042982; P:amyloid precursor protein metabolic process; TAS:UniProtKB.::GO:0007155; P:cell adhesion; TAS:UniProtKB.::GO:0008283; P:cell proliferation; TAS:UniProtKB.::GO:0019695; P:choline metabolic process; IBA:RefGenome.::GO:0006260; P:DNA replication; TAS:UniProtKB.::GO:0007517; P:muscle organ development; TAS:UniProtKB.::GO:0032223; P:negative regulation of synaptic transmission, cholinergic; IC:HGNC.::GO:0042136; P:neurotransmitter biosynthetic process; TAS:Reactome.::GO:0002076; P:osteoblast development; IEP:HGNC.::GO:0050714; P:positive regulation of protein secretion; TAS:UniProtKB.::GO:0050770; P:regulation of axonogenesis; IBA:RefGenome.::GO:0048814; P:regulation of dendrite morphogenesis; IBA:RefGenome.::GO:0009611; P:response to wounding; TAS:UniProtKB.::GO:0007416; P:synapse assembly; TAS:UniProtKB. | 10 | P81908 | 574 | CHLE_HORSE Cholinesterase OS=Equus caballus (... | 562 | 2e-36 | 147 | 28 | 42 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0003990; F:acetylcholinesterase activity; ISS:UniProtKB.::GO:0004091; F:carboxylesterase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 11 | P32749 | 602 | CHLE_BOVIN Cholinesterase OS=Bos taurus (Bovi... | 554 | 3e-36 | 147 | 28 | 43 | GO:0005788; C:endoplasmic reticulum lumen; IBA:RefGenome.::GO:0005615; C:extracellular space; IBA:RefGenome.::GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0003990; F:acetylcholinesterase activity; ISS:UniProtKB.::GO:0004091; F:carboxylesterase activity; IBA:RefGenome. | | | | | | | | | | GO:0019695; P:choline metabolic process; IBA:RefGenome.::GO:0007271; P:synaptic transmission, cholinergic; IBA:RefGenome. | 12 | Q869C3 | 737 | ACES_ANOGA Acetylcholinesterase OS=Anopheles ... | 613 | 3e-36 | 148 | 28 | 40 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003990; F:acetylcholinesterase activity; IBA:RefGenome.::GO:0004091; F:carboxylesterase activity; IBA:RefGenome. | | | | | | | | | | GO:0019695; P:choline metabolic process; IBA:RefGenome.::GO:0042135; P:neurotransmitter catabolic process; IEA:UniProtKB-KW.::GO:0007271; P:synaptic transmission, cholinergic; IBA:RefGenome. | 13 | P32949 | 549 | LIP5_CANRU Lipase 5 OS=Candida rugosa (Yeast)... | 537 | 5e-36 | 145 | 27 | 42 | | | | | | | | | | | GO:0050253; F:retinyl-palmitate esterase activity; IEA:EC.::GO:0004806; F:triglyceride lipase activity; IEA:EC. | | | | | | | | | | GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 14 | P79066 | 563 | LIP1_GEOFE Lipase 1 OS=Geotrichum fermentans ... | 588 | 5e-36 | 145 | 28 | 41 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050253; F:retinyl-palmitate esterase activity; IEA:EC.::GO:0004806; F:triglyceride lipase activity; IEA:EC. | | | | | | | | | | GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 15 | P22394 | 563 | LIP2_GEOCN Lipase 2 OS=Geotrichum candidum (O... | 608 | 3e-35 | 143 | 27 | 41 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050253; F:retinyl-palmitate esterase activity; IEA:EC.::GO:0004806; F:triglyceride lipase activity; IEA:EC. | | | | | | | | | | GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 16 | P56161 | 664 | ACES_ANOST Acetylcholinesterase OS=Anopheles ... | 407 | 4e-35 | 144 | 30 | 47 | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003990; F:acetylcholinesterase activity; IEA:EC.::GO:0004091; F:carboxylesterase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0001507; P:acetylcholine catabolic process in synaptic cleft; IEA:InterPro. | 17 | Q86GC8 | 702 | ACES_CULPI Acetylcholinesterase OS=Culex pipi... | 608 | 9e-35 | 143 | 28 | 40 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003990; F:acetylcholinesterase activity; IEA:EC.::GO:0004091; F:carboxylesterase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042135; P:neurotransmitter catabolic process; IEA:UniProtKB-KW. | 18 | Q99K10 | 843 | NLGN1_MOUSE Neuroligin-1 OS=Mus musculus (Mou... | 411 | 9e-35 | 144 | 31 | 46 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0009986; C:cell surface; ISS:BHF-UCL.::GO:0060076; C:excitatory synapse; IC:BHF-UCL.::GO:0005887; C:integral to plasma membrane; IMP:UniProtKB.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042043; F:neurexin family protein binding; IMP:UniProtKB.::GO:0046983; F:protein dimerization activity; ISS:BHF-UCL.::GO:0004872; F:receptor activity; IBA:RefGenome. | | | | | | | | | | GO:0097113; P:alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering; IDA:BHF-UCL.::GO:0016339; P:calcium-dependent cell-cell adhesion; ISS:UniProtKB.::GO:0048789; P:cytoskeletal matrix organization at active zone; IMP:BHF-UCL.::GO:0007157; P:heterophilic cell-cell adhesion; IDA:BHF-UCL.::GO:0097115; P:neurexin clustering; IDA:BHF-UCL.::GO:0007158; P:neuron cell-cell adhesion; IDA:BHF-UCL.::GO:0060999; P:positive regulation of dendritic spine development; ISS:BHF-UCL.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; IDA:BHF-UCL.::GO:0051965; P:positive regulation of synapse assembly; ISS:BHF-UCL.::GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; ISS:BHF-UCL.::GO:1900244; P:positive regulation of synaptic vesicle endocytosis; IMP:BHF-UCL.::GO:2000302; P:positive regulation of synaptic vesicle exocytosis; IMP:BHF-UCL.::GO:0097119; P:postsynaptic density protein 95 clustering; IDA:BHF-UCL.::GO:0097104; P:postsynaptic membrane assembly; IDA:BHF-UCL.::GO:0097105; P:presynaptic membrane assembly; IDA:BHF-UCL.::GO:0051260; P:protein homooligomerization; IDA:BHF-UCL.::GO:0097120; P:receptor localization to synapse; IDA:BHF-UCL.::GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:BHF-UCL.::GO:2000310; P:regulation of N-methyl-D-aspartate selective glutamate receptor activity; IDA:BHF-UCL.::GO:0002087; P:regulation of respiratory gaseous exchange by neurological system process; IGI:MGI.::GO:0097091; P:synaptic vesicle clustering; IDA:BHF-UCL.::GO:0016080; P:synaptic vesicle targeting; IMP:UniProtKB.::GO:0072553; P:terminal button organization; IMP:BHF-UCL. | 19 | Q8N2Q7 | 840 | NLGN1_HUMAN Neuroligin-1 OS=Homo sapiens (Hum... | 438 | 1e-34 | 144 | 31 | 44 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0009986; C:cell surface; ISS:BHF-UCL.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.::GO:0014069; C:postsynaptic density; TAS:BHF-UCL.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050839; F:cell adhesion molecule binding; ISS:BHF-UCL.::GO:0042043; F:neurexin family protein binding; ISS:UniProtKB.::GO:0046983; F:protein dimerization activity; ISS:BHF-UCL.::GO:0004872; F:receptor activity; ISS:BHF-UCL. | | | | | | | | | | GO:0097113; P:alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering; ISS:BHF-UCL.::GO:0016339; P:calcium-dependent cell-cell adhesion; ISS:UniProtKB.::GO:0048789; P:cytoskeletal matrix organization at active zone; ISS:BHF-UCL.::GO:0007157; P:heterophilic cell-cell adhesion; ISS:BHF-UCL.::GO:0097115; P:neurexin clustering; ISS:BHF-UCL.::GO:0007158; P:neuron cell-cell adhesion; ISS:BHF-UCL.::GO:0023041; P:neuronal signal transduction; TAS:BHF-UCL.::GO:0060999; P:positive regulation of dendritic spine development; ISS:BHF-UCL.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.::GO:0051491; P:positive regulation of filopodium assembly; ISS:BHF-UCL.::GO:0010740; P:positive regulation of intracellular protein kinase cascade; ISS:BHF-UCL.::GO:1900029; P:positive regulation of ruffle assembly; ISS:BHF-UCL.::GO:0051965; P:positive regulation of synapse assembly; ISS:BHF-UCL.::GO:0032230; P:positive regulation of synaptic transmission, GABAergic; ISS:BHF-UCL.::GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; ISS:BHF-UCL.::GO:1900244; P:positive regulation of synaptic vesicle endocytosis; ISS:BHF-UCL.::GO:2000302; P:positive regulation of synaptic vesicle exocytosis; ISS:BHF-UCL.::GO:0097119; P:postsynaptic density protein 95 clustering; ISS:BHF-UCL.::GO:0097104; P:postsynaptic membrane assembly; ISS:BHF-UCL.::GO:0097105; P:presynaptic membrane assembly; ISS:BHF-UCL.::GO:0051260; P:protein homooligomerization; ISS:BHF-UCL.::GO:0006605; P:protein targeting; ISS:UniProtKB.::GO:0097120; P:receptor localization to synapse; ISS:BHF-UCL.::GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:BHF-UCL.::GO:2000310; P:regulation of N-methyl-D-aspartate selective glutamate receptor activity; ISS:BHF-UCL.::GO:0097091; P:synaptic vesicle clustering; ISS:BHF-UCL.::GO:0016080; P:synaptic vesicle targeting; ISS:UniProtKB.::GO:0072553; P:terminal button organization; ISS:BHF-UCL. | 20 | Q03311 | 603 | CHLE_MOUSE Cholinesterase OS=Mus musculus (Mo... | 352 | 2e-34 | 141 | 35 | 46 | GO:0005788; C:endoplasmic reticulum lumen; IBA:RefGenome.::GO:0005615; C:extracellular space; IBA:RefGenome.::GO:0016020; C:membrane; IEA:InterPro.::GO:0005641; C:nuclear envelope lumen; IDA:MGI. | | | | | | | | | | GO:0003990; F:acetylcholinesterase activity; IDA:UniProtKB.::GO:0004091; F:carboxylesterase activity; IBA:RefGenome. | | | | | | | | | | GO:0019695; P:choline metabolic process; IBA:RefGenome.::GO:0007271; P:synaptic transmission, cholinergic; IBA:RefGenome. | 21 | P23795 | 613 | ACES_BOVIN Acetylcholinesterase OS=Bos taurus... | 554 | 2e-34 | 141 | 28 | 43 | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0030424; C:axon; IBA:RefGenome.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0009986; C:cell surface; IBA:RefGenome.::GO:0030425; C:dendrite; IBA:RefGenome.::GO:0005788; C:endoplasmic reticulum lumen; IBA:RefGenome.::GO:0005615; C:extracellular space; IBA:RefGenome.::GO:0031594; C:neuromuscular junction; IBA:RefGenome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IBA:RefGenome.::GO:0042734; C:presynaptic membrane; IBA:RefGenome. | | | | | | | | | | GO:0003990; F:acetylcholinesterase activity; IBA:RefGenome.::GO:0001540; F:beta-amyloid binding; IDA:HGNC.::GO:0004091; F:carboxylesterase activity; IBA:RefGenome. | | | | | | | | | | GO:0019695; P:choline metabolic process; IBA:RefGenome.::GO:0042135; P:neurotransmitter catabolic process; IEA:UniProtKB-KW.::GO:0050770; P:regulation of axonogenesis; IBA:RefGenome.::GO:0048814; P:regulation of dendrite morphogenesis; IBA:RefGenome.::GO:0007416; P:synapse assembly; IBA:RefGenome.::GO:0007271; P:synaptic transmission, cholinergic; IBA:RefGenome. | 22 | P17573 | 563 | LIP1_GEOCN Lipase 1 OS=Geotrichum candidum (O... | 591 | 9e-34 | 139 | 28 | 40 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050253; F:retinyl-palmitate esterase activity; IEA:EC.::GO:0004806; F:triglyceride lipase activity; IEA:EC. | | | | | | | | | | GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 23 | O62763 | 611 | ACES_FELCA Acetylcholinesterase OS=Felis catu... | 553 | 2e-33 | 139 | 28 | 43 | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003990; F:acetylcholinesterase activity; IEA:EC.::GO:0004091; F:carboxylesterase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042135; P:neurotransmitter catabolic process; IEA:UniProtKB-KW. | 24 | P37136 | 614 | ACES_RAT Acetylcholinesterase OS=Rattus norve... | 557 | 2e-33 | 139 | 29 | 42 | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0030424; C:axon; IDA:RGD.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0009986; C:cell surface; IDA:RGD.::GO:0030425; C:dendrite; IDA:RGD.::GO:0005788; C:endoplasmic reticulum lumen; IDA:RGD.::GO:0005615; C:extracellular space; IBA:RefGenome.::GO:0005794; C:Golgi apparatus; IDA:RGD.::GO:0031594; C:neuromuscular junction; IBA:RefGenome.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0005635; C:nuclear envelope; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:RGD.::GO:0045211; C:postsynaptic membrane; IDA:RGD.::GO:0042734; C:presynaptic membrane; IDA:RGD.::GO:0005791; C:rough endoplasmic reticulum; IDA:RGD. | | | | | | | | | | GO:0042166; F:acetylcholine binding; IDA:RGD.::GO:0003990; F:acetylcholinesterase activity; IDA:RGD.::GO:0004091; F:carboxylesterase activity; IBA:RefGenome.::GO:0033265; F:choline binding; IDA:RGD. | | | | | | | | | | GO:0006581; P:acetylcholine catabolic process; IDA:RGD.::GO:0019695; P:choline metabolic process; IDA:RGD.::GO:0070997; P:neuron death; IMP:RGD.::GO:0050772; P:positive regulation of axonogenesis; IMP:RGD.::GO:0050775; P:positive regulation of dendrite morphogenesis; IMP:RGD.::GO:0007416; P:synapse assembly; IMP:RGD.::GO:0007271; P:synaptic transmission, cholinergic; IBA:RefGenome. | 25 | Q8BYM5 | 825 | NLGN3_MOUSE Neuroligin-3 OS=Mus musculus (Mou... | 388 | 3e-33 | 139 | 31 | 46 | GO:0009986; C:cell surface; ISS:BHF-UCL.::GO:0030139; C:endocytic vesicle; ISS:BHF-UCL.::GO:0060076; C:excitatory synapse; ISS:BHF-UCL.::GO:0005887; C:integral to plasma membrane; ISS:BHF-UCL. | | | | | | | | | | GO:0050839; F:cell adhesion molecule binding; ISS:BHF-UCL.::GO:0042043; F:neurexin family protein binding; IBA:RefGenome.::GO:0004872; F:receptor activity; IBA:RefGenome. | | | | | | | | | | GO:0048675; P:axon extension; ISS:BHF-UCL.::GO:0007158; P:neuron cell-cell adhesion; ISS:BHF-UCL.::GO:2000969; P:positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; IMP:BHF-UCL.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; IMP:BHF-UCL.::GO:0051965; P:positive regulation of synapse assembly; ISS:BHF-UCL.::GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; IMP:BHF-UCL.::GO:0097104; P:postsynaptic membrane assembly; IMP:BHF-UCL.::GO:0097105; P:presynaptic membrane assembly; ISS:BHF-UCL.::GO:0006898; P:receptor-mediated endocytosis; ISS:BHF-UCL.::GO:0060080; P:regulation of inhibitory postsynaptic membrane potential; IMP:MGI.::GO:0060024; P:rhythmic synaptic transmission; ISS:BHF-UCL.::GO:0035176; P:social behavior; IMP:MGI.::GO:0008542; P:visual learning; IMP:MGI. | 26 | P07140 | 649 | ACES_DROME Acetylcholinesterase OS=Drosophila... | 355 | 5e-33 | 138 | 31 | 48 | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0005886; C:plasma membrane; IDA:FlyBase. | | | | | | | | | | GO:0003990; F:acetylcholinesterase activity; IDA:FlyBase.::GO:0004091; F:carboxylesterase activity; IBA:RefGenome.::GO:0042803; F:protein homodimerization activity; IMP:FlyBase. | | | | | | | | | | GO:0001507; P:acetylcholine catabolic process in synaptic cleft; IEA:InterPro.::GO:0042426; P:choline catabolic process; IDA:FlyBase.::GO:0042331; P:phototaxis; IMP:FlyBase. | 27 | Q62765 | 843 | NLGN1_RAT Neuroligin-1 OS=Rattus norvegicus (... | 411 | 5e-33 | 139 | 30 | 45 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0009986; C:cell surface; IDA:BHF-UCL.::GO:0060076; C:excitatory synapse; IC:BHF-UCL.::GO:0032433; C:filopodium tip; IDA:BHF-UCL.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050839; F:cell adhesion molecule binding; IPI:BHF-UCL.::GO:0042043; F:neurexin family protein binding; ISS:UniProtKB.::GO:0046983; F:protein dimerization activity; IDA:BHF-UCL.::GO:0004872; F:receptor activity; IDA:BHF-UCL. | | | | | | | | | | GO:0097113; P:alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering; ISS:BHF-UCL.::GO:0016339; P:calcium-dependent cell-cell adhesion; IDA:UniProtKB.::GO:0048789; P:cytoskeletal matrix organization at active zone; IMP:BHF-UCL.::GO:0007157; P:heterophilic cell-cell adhesion; ISS:BHF-UCL.::GO:0097114; P:N-methyl-D-aspartate receptor clustering; IDA:BHF-UCL.::GO:0097115; P:neurexin clustering; ISS:BHF-UCL.::GO:0007158; P:neuron cell-cell adhesion; IDA:BHF-UCL.::GO:0045161; P:neuronal ion channel clustering; TAS:UniProtKB.::GO:0060999; P:positive regulation of dendritic spine development; IDA:BHF-UCL.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; IDA:BHF-UCL.::GO:0051491; P:positive regulation of filopodium assembly; IDA:BHF-UCL.::GO:0010740; P:positive regulation of intracellular protein kinase cascade; IDA:BHF-UCL.::GO:1900029; P:positive regulation of ruffle assembly; IDA:BHF-UCL.::GO:0051965; P:positive regulation of synapse assembly; IDA:BHF-UCL.::GO:0032230; P:positive regulation of synaptic transmission, GABAergic; IDA:BHF-UCL.::GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; IDA:BHF-UCL.::GO:1900244; P:positive regulation of synaptic vesicle endocytosis; IMP:BHF-UCL.::GO:2000302; P:positive regulation of synaptic vesicle exocytosis; IMP:BHF-UCL.::GO:0097119; P:postsynaptic density protein 95 clustering; IDA:BHF-UCL.::GO:0097104; P:postsynaptic membrane assembly; ISS:BHF-UCL.::GO:0097105; P:presynaptic membrane assembly; IDA:BHF-UCL.::GO:0051290; P:protein heterotetramerization; IDA:RGD.::GO:0051260; P:protein homooligomerization; ISS:BHF-UCL.::GO:0006605; P:protein targeting; IDA:UniProtKB.::GO:0097120; P:receptor localization to synapse; ISS:BHF-UCL.::GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; IDA:BHF-UCL.::GO:2000310; P:regulation of N-methyl-D-aspartate selective glutamate receptor activity; IDA:BHF-UCL.::GO:0097091; P:synaptic vesicle clustering; IMP:BHF-UCL.::GO:0016080; P:synaptic vesicle targeting; ISS:UniProtKB.::GO:0072553; P:terminal button organization; IMP:BHF-UCL. | 28 | P04058 | 586 | ACES_TORCA Acetylcholinesterase OS=Torpedo ca... | 349 | 7e-33 | 137 | 34 | 50 | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003990; F:acetylcholinesterase activity; IEA:EC.::GO:0004091; F:carboxylesterase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0001507; P:acetylcholine catabolic process in synaptic cleft; IEA:InterPro. | 29 | Q8N0W4 | 816 | NLGNX_HUMAN Neuroligin-4, X-linked OS=Homo sa... | 400 | 7e-33 | 138 | 30 | 44 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0060076; C:excitatory synapse; IDA:BHF-UCL.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0031404; F:chloride ion binding; IDA:UniProtKB.::GO:0042043; F:neurexin family protein binding; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0004872; F:receptor activity; IBA:RefGenome. | | | | | | | | | | GO:0003360; P:brainstem development; ISS:BHF-UCL.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0045216; P:cell-cell junction organization; NAS:UniProtKB.::GO:0021549; P:cerebellum development; ISS:BHF-UCL.::GO:0090394; P:negative regulation of excitatory postsynaptic membrane potential; IDA:BHF-UCL.::GO:0046622; P:positive regulation of organ growth; ISS:BHF-UCL.::GO:0097105; P:presynaptic membrane assembly; IDA:BHF-UCL.::GO:0035176; P:social behavior; IMP:UniProtKB.::GO:0071625; P:vocalization behavior; IMP:BHF-UCL. | 30 | P21836 | 614 | ACES_MOUSE Acetylcholinesterase OS=Mus muscul... | 557 | 1e-32 | 136 | 29 | 42 | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0030424; C:axon; IBA:RefGenome.::GO:0005605; C:basal lamina; IDA:MGI.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0009986; C:cell surface; IDA:MGI.::GO:0030425; C:dendrite; IBA:RefGenome.::GO:0005788; C:endoplasmic reticulum lumen; IBA:RefGenome.::GO:0005615; C:extracellular space; IDA:MGI.::GO:0031594; C:neuromuscular junction; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0045211; C:postsynaptic membrane; IBA:RefGenome.::GO:0042734; C:presynaptic membrane; IBA:RefGenome. | | | | | | | | | | GO:0003990; F:acetylcholinesterase activity; IDA:MGI.::GO:0004091; F:carboxylesterase activity; IBA:RefGenome.::GO:0043621; F:protein self-association; IPI:MGI. | | | | | | | | | | GO:0006581; P:acetylcholine catabolic process; IDA:MGI.::GO:0019695; P:choline metabolic process; IBA:RefGenome.::GO:0045212; P:neurotransmitter receptor biosynthetic process; IMP:MGI.::GO:0051262; P:protein tetramerization; IDA:MGI.::GO:0031623; P:receptor internalization; IMP:MGI.::GO:0050770; P:regulation of axonogenesis; IBA:RefGenome.::GO:0048814; P:regulation of dendrite morphogenesis; IBA:RefGenome.::GO:0001919; P:regulation of receptor recycling; IMP:MGI.::GO:0060041; P:retina development in camera-type eye; IMP:MGI.::GO:0007416; P:synapse assembly; IBA:RefGenome.::GO:0007271; P:synaptic transmission, cholinergic; IBA:RefGenome. | 31 | Q29499 | 584 | ACES_RABIT Acetylcholinesterase OS=Oryctolagu... | 554 | 2e-32 | 135 | 27 | 42 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003990; F:acetylcholinesterase activity; IEA:EC.::GO:0004091; F:carboxylesterase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042135; P:neurotransmitter catabolic process; IEA:UniProtKB-KW. |
