rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | O75592 | 4640 | MYCB2_HUMAN Probable E3 ubiquitin-protein lig... | 143 | 0.7 | 37 | 22 | 41 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 62 | Q9NB71 | 5233 | HIW_DROME E3 ubiquitin-protein ligase highwir... | 199 | 4.6 | 34.3 | 23 | 42 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IDA:FlyBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:FlyBase. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007628; P:adult walking behavior; NAS:FlyBase.::GO:0006914; P:autophagy; IDA:FlyBase.::GO:0030509; P:BMP signaling pathway; IPI:UniProtKB.::GO:0040011; P:locomotion; NAS:FlyBase.::GO:0030514; P:negative regulation of BMP signaling pathway; IGI:UniProtKB.::GO:0045886; P:negative regulation of synaptic growth at neuromuscular junction; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050808; P:synapse organization; IDA:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 63 | Q17551 | 3766 | RPM1_CAEEL E3 ubiquitin-protein ligase rpm-1 ... | 107 | 8.8 | 33.5 | 23 | 37 | GO:0030424; C:axon; IDA:WormBase.::GO:0031594; C:neuromuscular junction; IDA:WormBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:WormBase.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:WormBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0040011; P:locomotion; IGI:WormBase.::GO:0043409; P:negative regulation of MAPK cascade; IGI:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0031647; P:regulation of protein stability; IMP:WormBase.::GO:0050807; P:regulation of synapse organization; IMP:WormBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 64 | Q7TPH6 | 4711 | MYCB2_MOUSE Probable E3 ubiquitin-protein lig... | 143 | 0.78 | 37 | 23 | 41 | GO:0030424; C:axon; IDA:MGI.::GO:0015630; C:microtubule cytoskeleton; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0021785; P:branchiomotor neuron axon guidance; IMP:MGI.::GO:0021952; P:central nervous system projection neuron axonogenesis; IMP:MGI.::GO:0051493; P:regulation of cytoskeleton organization; IMP:MGI.::GO:0032880; P:regulation of protein localization; IMP:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 65 | Q6NRS1 | 1339 | IBTK_XENLA Inhibitor of Bruton tyrosine kinas... | 154 | 0.001 | 45.8 | 27 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 66 | P0C7G9 | 704 | RCCDB_DICDI RCC1 domain-containing protein DD... | 94 | 1.5 | 35.8 | 28 | 43 | | | | | | | | | | | | | | | | | | | | | | 67 | Q6ZRI0 | 2925 | OTOG_HUMAN Otogelin OS=Homo sapiens (Human). ... | 217 | 0.02 | 42 | 23 | 36 | GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046556; F:alpha-N-arabinofuranosidase activity; IEA:InterPro. | | | | | | | | | | GO:0046373; P:L-arabinose metabolic process; IEA:InterPro. | 68 | Q9P2D0 | 1353 | IBTK_HUMAN Inhibitor of Bruton tyrosine kinas... | 92 | 0.029 | 41.6 | 29 | 46 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0019901; F:protein kinase binding; IDA:MGI.::GO:0030292; F:protein tyrosine kinase inhibitor activity; IDA:MGI. | | | | | | | | | | GO:0001933; P:negative regulation of protein phosphorylation; IDA:MGI.::GO:0051209; P:release of sequestered calcium ion into cytosol; IDA:MGI. | 69 | Q28983 | 2476 | ZAN_PIG Zonadhesin OS=Sus scrofa (Pig). GN=ZA... | 122 | 0.042 | 40.8 | 30 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0050840; F:extracellular matrix binding; IDA:MGI. | | | | | | | | | | GO:0007339; P:binding of sperm to zona pellucida; IDA:MGI.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 70 | Q4R327 | 580 | FBX24_MACFA F-box only protein 24 OS=Macaca f... | 118 | 0.079 | 39.7 | 26 | 47 | | | | | | | | | | | | | | | | | | | | | | 71 | O01761 | 8081 | UNC89_CAEEL Muscle M-line assembly protein un... | 196 | 5.6 | 34.3 | 26 | 47 | GO:0005887; C:integral to plasma membrane; IEA:InterPro.::GO:0031430; C:M band; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:InterPro.::GO:0019902; F:phosphatase binding; IPI:WormBase.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017048; F:Rho GTPase binding; IPI:WormBase.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IDA:WormBase.::GO:0005021; F:vascular endothelial growth factor-activated receptor activity; IEA:InterPro. | | | | | | | | | | GO:0040011; P:locomotion; IMP:WormBase.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0030241; P:skeletal muscle myosin thick filament assembly; IMP:WormBase.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IEA:InterPro. | 72 | O75426 | 580 | FBX24_HUMAN F-box only protein 24 OS=Homo sap... | 118 | 0.084 | 39.7 | 26 | 47 | GO:0000151; C:ubiquitin ligase complex; NAS:UniProtKB. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB. | | | | | | | | | | | 73 | P31471 | 389 | YIEL_ECOLI Uncharacterized protein yieL OS=Es... | 89 | 0.23 | 38.1 | 34 | 45 | | | | | | | | | | | GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; IEA:InterPro. | 74 | P0C656 | 3902 | MED12_CAEBR Mediator of RNA polymerase II tra... | 214 | 0.26 | 38.5 | 25 | 38 | GO:0016592; C:mediator complex; IEA:InterPro. | | | | | | | | | | GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro. | | | | | | | | | | | 75 | A2ARZ3 | 6995 | FSIP2_MOUSE Fibrous sheath-interacting protei... | 150 | 0.33 | 38.1 | 23 | 35 | GO:0009434; C:microtubule-based flagellum; IC:MGI.::GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | | 76 | P54282 | 2212 | CAC1A_RAT Voltage-dependent P/Q-type calcium ... | 181 | 0.38 | 37.7 | 25 | 42 | GO:0043204; C:perikaryon; IDA:RGD.::GO:0005891; C:voltage-gated calcium channel complex; IDA:RGD. | | | | | | | | | | GO:0005516; F:calmodulin binding; IDA:UniProtKB. | | | | | | | | | | GO:0007204; P:elevation of cytosolic calcium ion concentration; ISS:UniProtKB. | 77 | O41965 | 2457 | DEN_MHV68 Deneddylase ORF64 OS=Murid herpesvi... | 187 | 0.51 | 37.4 | 24 | 35 | GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.::GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.::GO:0019033; C:viral tegument; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 78 | O75962 | 3097 | TRIO_HUMAN Triple functional domain protein O... | 170 | 0.56 | 37.4 | 22 | 39 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; TAS:ProtInc. | 79 | P38352 | 637 | SAF1_YEAST SCF-associated factor 1 OS=Sacchar... | 53 | 1.6 | 35.4 | 36 | 51 | GO:0019005; C:SCF ubiquitin ligase complex; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0016567; P:protein ubiquitination; IMP:GOC.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IMP:SGD. | 80 | A7Y3K2 | 2057 | YCF1_IPOPU Putative membrane protein ycf1 OS=... | 204 | 1.6 | 35.8 | 23 | 40 | GO:0031969; C:chloroplast membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 81 | Q6ZPR6 | 1352 | IBTK_MOUSE Inhibitor of Bruton tyrosine kinas... | 80 | 1 | 36.2 | 29 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 82 | Q9BXB4 | 747 | OSB11_HUMAN Oxysterol-binding protein-related... | 109 | 1.1 | 36.2 | 27 | 47 | | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0006869; P:lipid transport; IEA:UniProtKB-KW. | 83 | Q9Y493 | 2812 | ZAN_HUMAN Zonadhesin OS=Homo sapiens (Human).... | 170 | 1.5 | 35.8 | 22 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; NAS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0007339; P:binding of sperm to zona pellucida; NAS:UniProtKB.::GO:0016337; P:cell-cell adhesion; NAS:UniProtKB. | 84 | Q20497 | 3498 | MED12_CAEEL Mediator of RNA polymerase II tra... | 138 | 1.8 | 35.8 | 22 | 33 | GO:0016592; C:mediator complex; IEA:InterPro. | | | | | | | | | | GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro. | | | | | | | | | | GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0040026; P:positive regulation of vulval development; IMP:WormBase. | 85 | P53804 | 2025 | TTC3_HUMAN E3 ubiquitin-protein ligase TTC3 O... | 100 | 4.7 | 34.3 | 27 | 41 | GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:UniProtKB. | 86 | A1KU05 | 589 | CYSI_NEIMF Sulfite reductase [NADPH] hemoprot... | 83 | 5.7 | 33.9 | 31 | 41 | GO:0009337; C:sulfite reductase complex (NADPH); IEA:InterPro. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004783; F:sulfite reductase (NADPH) activity; IEA:EC. | | | | | | | | | | GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW. | 87 | Q9JS33 | 589 | CYSI_NEIMB Sulfite reductase [NADPH] hemoprot... | 83 | 6.3 | 33.5 | 31 | 41 | GO:0009337; C:sulfite reductase complex (NADPH); IEA:InterPro. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004783; F:sulfite reductase (NADPH) activity; IEA:EC. | | | | | | | | | | GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW. | 88 | Q9JUD9 | 589 | CYSI_NEIMA Sulfite reductase [NADPH] hemoprot... | 83 | 6.8 | 33.5 | 31 | 41 | GO:0009337; C:sulfite reductase complex (NADPH); IEA:InterPro. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004783; F:sulfite reductase (NADPH) activity; IEA:EC. | | | | | | | | | | GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW. | 89 | A9LZ72 | 589 | CYSI_NEIM0 Sulfite reductase [NADPH] hemoprot... | 83 | 7 | 33.5 | 31 | 41 | GO:0009337; C:sulfite reductase complex (NADPH); IEA:InterPro. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004783; F:sulfite reductase (NADPH) activity; IEA:EC. | | | | | | | | | | GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW. | 90 | Q9P219 | 2028 | DAPLE_HUMAN Protein Daple OS=Homo sapiens (Hu... | 188 | 7.1 | 33.9 | 21 | 34 | GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005626; C:insoluble fraction; ISS:UniProtKB. | | | | | | | | | | GO:0008017; F:microtubule binding; IEA:InterPro.::GO:0030165; F:PDZ domain binding; ISS:UniProtKB.::GO:0043621; F:protein self-association; ISS:UniProtKB. | | | | | | | | | | GO:0000226; P:microtubule cytoskeleton organization; IEA:InterPro.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.::GO:0001932; P:regulation of protein phosphorylation; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 91 | Q24574 | 1556 | UBPE_DROME Ubiquitin carboxyl-terminal hydrol... | 165 | 7.4 | 33.5 | 26 | 41 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro. | | | | | | | | | | GO:0031935; P:regulation of chromatin silencing; IMP:FlyBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. |