| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q8GXJ1 | 552 | HDA15_ARATH Histone deacetylase 15 OS=Arabido... | 258 | 0.0000001 | 59.7 | 27 | 43 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009294; P:DNA mediated transformation; IMP:TAIR.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 32 | Q48935 | 341 | APHA_MYCRA Acetylpolyamine aminohydrolase OS=... | 104 | 0.0000002 | 57.8 | 33 | 48 | | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 33 | O17323 | 816 | HDA4_CAEEL Histone deacetylase 4 OS=Caenorhab... | 75 | 0.0000006 | 57.4 | 37 | 59 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 34 | Q09440 | 507 | HDA2_CAEEL Putative histone deacetylase 2 OS=... | 70 | 0.000001 | 55.8 | 39 | 60 | GO:0000118; C:histone deacetylase complex; ISS:WormBase. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0003714; F:transcription corepressor activity; ISS:WormBase. | | | | | | | | | | GO:0042262; P:DNA protection; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040017; P:positive regulation of locomotion; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0006974; P:response to DNA damage stimulus; IMP:WormBase.::GO:0045138; P:tail tip morphogenesis; IMP:WormBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 35 | P53973 | 706 | HDA1_YEAST Histone deacetylase HDA1 OS=Saccha... | 377 | 0.000002 | 55.5 | 25 | 41 | GO:0070823; C:HDA1 complex; IDA:SGD. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:SGD.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC. | | | | | | | | | | GO:0031047; P:gene silencing by RNA; IMP:SGD.::GO:0010978; P:gene silencing involved in chronological cell aging; IMP:SGD.::GO:0001308; P:negative regulation of chromatin silencing involved in replicative cell aging; IMP:SGD.::GO:0010621; P:negative regulation of transcription by transcription factor localization; IGI:SGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0031938; P:regulation of chromatin silencing at telomere; IMP:SGD.::GO:0034401; P:regulation of transcription by chromatin organization; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 36 | Q94EJ2 | 377 | HDA8_ARATH Histone deacetylase 8 OS=Arabidops... | 80 | 0.000003 | 54.3 | 30 | 54 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 37 | Q3JUN4 | 341 | APHA_BURP1 Acetylpolyamine aminohydrolase OS=... | 252 | 0.00001 | 52.4 | 26 | 38 | | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 38 | P53096 | 452 | HOS2_YEAST Probable histone deacetylase HOS2 ... | 70 | 0.00002 | 52.4 | 40 | 57 | GO:0070210; C:Rpd3L-Expanded complex; IDA:SGD.::GO:0034967; C:Set3 complex; IDA:SGD. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0045129; F:NAD-independent histone deacetylase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0045835; P:negative regulation of meiosis; IMP:SGD.::GO:0032874; P:positive regulation of stress-activated MAPK cascade; IMP:SGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 39 | Q94517 | 521 | HDAC1_DROME Histone deacetylase Rpd3 OS=Droso... | 68 | 0.00005 | 50.8 | 34 | 53 | GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0035098; C:ESC/E(Z) complex; IDA:FlyBase.::GO:0031523; C:Myb complex; IDA:FlyBase.::GO:0016581; C:NuRD complex; IPI:FlyBase.::GO:0005705; C:polytene chromosome interband; IDA:FlyBase.::GO:0016580; C:Sin3 complex; NAS:FlyBase. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0003714; F:transcription corepressor activity; IPI:FlyBase.::GO:0008134; F:transcription factor binding; TAS:UniProtKB. | | | | | | | | | | GO:0007350; P:blastoderm segmentation; IMP:FlyBase.::GO:0006342; P:chromatin silencing; IMP:FlyBase.::GO:0070983; P:dendrite guidance; IMP:FlyBase.::GO:0008340; P:determination of adult lifespan; IMP:FlyBase.::GO:0007517; P:muscle organ development; IMP:FlyBase.::GO:0050771; P:negative regulation of axonogenesis; IMP:FlyBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:FlyBase.::GO:0048477; P:oogenesis; TAS:FlyBase.::GO:0022904; P:respiratory electron transport chain; IDA:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IDA:FlyBase. | 40 | P56518 | 576 | HDAC1_STRPU Histone deacetylase 1 OS=Strongyl... | 83 | 0.00005 | 51.2 | 31 | 48 | GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0000118; C:histone deacetylase complex; TAS:UniProtKB. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0008134; F:transcription factor binding; TAS:UniProtKB. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 41 | O42227 | 480 | HDA1B_XENLA Probable histone deacetylase 1-B ... | 68 | 0.00009 | 50.1 | 34 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 42 | Q12214 | 470 | HOS1_YEAST Histone deacetylase HOS1 OS=Saccha... | 82 | 0.0001 | 49.7 | 33 | 55 | GO:0000118; C:histone deacetylase complex; TAS:SGD. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC. | | | | | | | | | | GO:0034983; P:peptidyl-lysine deacetylation; IMP:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 43 | Q92769 | 488 | HDAC2_HUMAN Histone deacetylase 2 OS=Homo sap... | 68 | 0.0002 | 49.3 | 32 | 51 | GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0035098; C:ESC/E(Z) complex; IDA:UniProtKB.::GO:0016581; C:NuRD complex; IDA:UniProtKB.::GO:0016580; C:Sin3 complex; IDA:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0043565; F:sequence-specific DNA binding; IDA:BHF-UCL.::GO:0008134; F:transcription factor binding; IPI:BHF-UCL. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0006338; P:chromatin remodeling; IC:BHF-UCL.::GO:0016358; P:dendrite development; ISS:UniProtKB.::GO:0042733; P:embryonic digit morphogenesis; ISS:BHF-UCL.::GO:0009913; P:epidermal cell differentiation; ISS:BHF-UCL.::GO:0061029; P:eyelid development in camera-type eye; ISS:BHF-UCL.::GO:0061198; P:fungiform papilla formation; ISS:BHF-UCL.::GO:0060789; P:hair follicle placode formation; ISS:BHF-UCL.::GO:0006344; P:maintenance of chromatin silencing; IMP:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; ISS:BHF-UCL.::GO:0045786; P:negative regulation of cell cycle; TAS:Reactome.::GO:0045347; P:negative regulation of MHC class II biosynthetic process; IC:BHF-UCL.::GO:0010977; P:negative regulation of neuron projection development; ISS:BHF-UCL.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0042475; P:odontogenesis of dentin-containing tooth; ISS:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.::GO:0032967; P:positive regulation of collagen biosynthetic process; IC:BHF-UCL.::GO:0045862; P:positive regulation of proteolysis; IMP:BHF-UCL.::GO:0010870; P:positive regulation of receptor biosynthetic process; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 44 | P70288 | 488 | HDAC2_MOUSE Histone deacetylase 2 OS=Mus musc... | 68 | 0.0002 | 49.3 | 32 | 51 | GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0035098; C:ESC/E(Z) complex; ISS:UniProtKB.::GO:0000792; C:heterochromatin; IDA:MGI.::GO:0000118; C:histone deacetylase complex; TAS:UniProtKB.::GO:0000790; C:nuclear chromatin; IDA:BHF-UCL.::GO:0005657; C:replication fork; IDA:MGI.::GO:0005667; C:transcription factor complex; IPI:MGI.::GO:0017053; C:transcriptional repressor complex; IPI:MGI. | | | | | | | | | | GO:0031490; F:chromatin DNA binding; IDA:MGI.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008134; F:transcription factor binding; TAS:UniProtKB. | | | | | | | | | | GO:0016358; P:dendrite development; IMP:UniProtKB.::GO:0042733; P:embryonic digit morphogenesis; IGI:BHF-UCL.::GO:0009913; P:epidermal cell differentiation; IGI:BHF-UCL.::GO:0061029; P:eyelid development in camera-type eye; IGI:BHF-UCL.::GO:0061198; P:fungiform papilla formation; IGI:BHF-UCL.::GO:0060789; P:hair follicle placode formation; IGI:BHF-UCL.::GO:0021766; P:hippocampus development; IGI:MGI.::GO:0043066; P:negative regulation of apoptotic process; IGI:BHF-UCL.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IGI:MGI.::GO:0010977; P:negative regulation of neuron projection development; IDA:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:BHF-UCL.::GO:0042475; P:odontogenesis of dentin-containing tooth; IGI:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IGI:BHF-UCL.::GO:0048714; P:positive regulation of oligodendrocyte differentiation; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 45 | Q5RB76 | 428 | HDAC3_PONAB Histone deacetylase 3 OS=Pongo ab... | 77 | 0.0002 | 48.9 | 34 | 51 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 46 | O15379 | 428 | HDAC3_HUMAN Histone deacetylase 3 OS=Homo sap... | 77 | 0.0002 | 48.9 | 34 | 51 | GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0000118; C:histone deacetylase complex; TAS:UniProtKB.::GO:0005876; C:spindle microtubule; IDA:UniProtKB.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB. | | | | | | | | | | GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0003714; F:transcription corepressor activity; IMP:UniProtKB.::GO:0008134; F:transcription factor binding; TAS:UniProtKB. | | | | | | | | | | GO:0006916; P:anti-apoptosis; TAS:ProtInc.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0045786; P:negative regulation of cell cycle; TAS:Reactome.::GO:0046329; P:negative regulation of JNK cascade; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0051225; P:spindle assembly; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 47 | P56520 | 428 | HDAC3_CHICK Histone deacetylase 3 OS=Gallus g... | 77 | 0.0002 | 48.9 | 34 | 51 | GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0000118; C:histone deacetylase complex; TAS:UniProtKB. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0008134; F:transcription factor binding; TAS:UniProtKB. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 48 | Q6P6W3 | 428 | HDAC3_RAT Histone deacetylase 3 OS=Rattus nor... | 77 | 0.0002 | 48.9 | 34 | 51 | GO:0000785; C:chromatin; IDA:RGD.::GO:0005737; C:cytoplasm; IDA:RGD. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC. | | | | | | | | | | GO:0070932; P:histone H3 deacetylation; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 49 | P56517 | 480 | HDAC1_CHICK Histone deacetylase 1 OS=Gallus g... | 68 | 0.0002 | 48.9 | 32 | 51 | | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC. | | | | | | | | | | | 50 | O88895 | 424 | HDAC3_MOUSE Histone deacetylase 3 OS=Mus musc... | 77 | 0.0002 | 48.9 | 34 | 51 | GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0000118; C:histone deacetylase complex; TAS:UniProtKB. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0008134; F:transcription factor binding; TAS:UniProtKB. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 51 | Q91695 | 480 | HDA1A_XENLA Probable histone deacetylase 1-A ... | 68 | 0.0002 | 48.9 | 32 | 51 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 52 | P56519 | 488 | HDAC2_CHICK Histone deacetylase 2 OS=Gallus g... | 62 | 0.0002 | 48.9 | 35 | 58 | GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0035098; C:ESC/E(Z) complex; ISS:UniProtKB.::GO:0000118; C:histone deacetylase complex; TAS:UniProtKB. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0008134; F:transcription factor binding; TAS:UniProtKB. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 53 | Q6IRL9 | 428 | HDAC3_XENLA Histone deacetylase 3 OS=Xenopus ... | 77 | 0.0002 | 48.5 | 34 | 51 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 54 | B1H369 | 369 | HDAC8_XENTR Histone deacetylase 8 OS=Xenopus ... | 113 | 0.0003 | 48.1 | 28 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 55 | O09106 | 482 | HDAC1_MOUSE Histone deacetylase 1 OS=Mus musc... | 68 | 0.0003 | 48.5 | 32 | 51 | GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0000792; C:heterochromatin; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0000790; C:nuclear chromatin; IDA:BHF-UCL.::GO:0016581; C:NuRD complex; IDA:MGI.::GO:0005667; C:transcription factor complex; IDA:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:MGI.::GO:0003677; F:DNA binding; IDA:MGI.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0003714; F:transcription corepressor activity; IDA:MGI. | | | | | | | | | | GO:0042733; P:embryonic digit morphogenesis; IGI:BHF-UCL.::GO:0007492; P:endoderm development; IDA:MGI.::GO:0009913; P:epidermal cell differentiation; IGI:BHF-UCL.::GO:0061029; P:eyelid development in camera-type eye; IGI:BHF-UCL.::GO:0061198; P:fungiform papilla formation; IGI:BHF-UCL.::GO:0060789; P:hair follicle placode formation; IGI:BHF-UCL.::GO:0021766; P:hippocampus development; IGI:MGI.::GO:0043066; P:negative regulation of apoptotic process; IGI:BHF-UCL.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IGI:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:BHF-UCL.::GO:0030182; P:neuron differentiation; IGI:MGI.::GO:0042475; P:odontogenesis of dentin-containing tooth; IGI:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IGI:BHF-UCL.::GO:0048714; P:positive regulation of oligodendrocyte differentiation; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 56 | Q4QQW4 | 482 | HDAC1_RAT Histone deacetylase 1 OS=Rattus nor... | 68 | 0.0003 | 48.5 | 32 | 51 | GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 57 | Q32PJ8 | 482 | HDAC1_BOVIN Histone deacetylase 1 OS=Bos taur... | 68 | 0.0003 | 48.5 | 32 | 51 | | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC. | | | | | | | | | | | 58 | Q5RAG0 | 482 | HDAC1_PONAB Histone deacetylase 1 OS=Pongo ab... | 68 | 0.0003 | 48.1 | 32 | 51 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 59 | Q13547 | 482 | HDAC1_HUMAN Histone deacetylase 1 OS=Homo sap... | 68 | 0.0003 | 48.1 | 32 | 51 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0016581; C:NuRD complex; IDA:UniProtKB.::GO:0016580; C:Sin3 complex; IDA:BHF-UCL. | | | | | | | | | | GO:0033613; F:activating transcription factor binding; IPI:UniProtKB.::GO:0001047; F:core promoter binding; IDA:UniProtKB.::GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0001106; F:RNA polymerase II transcription corepressor activity; IDA:BHF-UCL.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc. | | | | | | | | | | GO:0006916; P:anti-apoptosis; TAS:ProtInc.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0006338; P:chromatin remodeling; IC:BHF-UCL.::GO:0042733; P:embryonic digit morphogenesis; ISS:BHF-UCL.::GO:0009913; P:epidermal cell differentiation; ISS:BHF-UCL.::GO:0061029; P:eyelid development in camera-type eye; ISS:BHF-UCL.::GO:0061198; P:fungiform papilla formation; ISS:BHF-UCL.::GO:0060789; P:hair follicle placode formation; ISS:BHF-UCL.::GO:0070932; P:histone H3 deacetylation; IDA:BHF-UCL.::GO:0070933; P:histone H4 deacetylation; IDA:BHF-UCL.::GO:0000278; P:mitotic cell cycle; TAS:Reactome.::GO:0043922; P:negative regulation by host of viral transcription; IMP:UniProtKB.::GO:0060766; P:negative regulation of androgen receptor signaling pathway; IDA:BHF-UCL.::GO:0045786; P:negative regulation of cell cycle; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0042475; P:odontogenesis of dentin-containing tooth; ISS:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.::GO:0010870; P:positive regulation of receptor biosynthetic process; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL. | 60 | Q28DV3 | 428 | HDAC3_XENTR Histone deacetylase 3 OS=Xenopus ... | 77 | 0.0004 | 47.8 | 32 | 51 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 61 | O17695 | 461 | HDA1_CAEEL Histone deacetylase 1 OS=Caenorhab... | 77 | 0.0004 | 47.8 | 31 | 51 | GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0043073; C:germ cell nucleus; IDA:WormBase.::GO:0000118; C:histone deacetylase complex; IPI:WormBase. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0048557; P:embryonic digestive tract morphogenesis; IGI:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0045746; P:negative regulation of Notch signaling pathway; IMP:WormBase.::GO:0046580; P:negative regulation of Ras protein signal transduction; IGI:WormBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0045595; P:regulation of cell differentiation; IGI:WormBase.::GO:0006974; P:response to DNA damage stimulus; IMP:WormBase.::GO:0045138; P:tail tip morphogenesis; IMP:WormBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
