| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | Q15811 | 1721 | ITSN1_HUMAN Intersectin-1 OS=Homo sapiens (Hu... | 97 | 1.8 | 33.9 | 19 | 43 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005905; C:coated pit; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; NAS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0070064; F:proline-rich region binding; IPI:UniProtKB.::GO:0032947; F:protein complex scaffold; IDA:UniProtKB.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0048488; P:synaptic vesicle endocytosis; TAS:ProtInc. | 62 | Q6C908 | 1634 | PAN1_YARLI Actin cytoskeleton-regulatory comp... | 99 | 0.038 | 39.3 | 23 | 47 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 63 | Q5AHB1 | 1397 | PAN1_CANAL Actin cytoskeleton-regulatory comp... | 95 | 0.0008 | 44.7 | 24 | 47 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0030427; C:site of polarized growth; IDA:CGD. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IMP:CGD.::GO:0009826; P:unidimensional cell growth; IMP:CGD. | 64 | A6ZVS5 | 1460 | PAN1_YEAS7 Actin cytoskeleton-regulatory comp... | 60 | 0.00000007 | 57 | 43 | 57 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 65 | Q8BH64 | 543 | EHD2_MOUSE EH domain-containing protein 2 OS=... | 85 | 0.00000006 | 57 | 41 | 54 | GO:0005624; C:membrane fraction; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0019904; F:protein domain specific binding; IDA:MGI. | | | | | | | | | | GO:0030866; P:cortical actin cytoskeleton organization; IDA:MGI.::GO:0032456; P:endocytic recycling; ISS:UniProtKB.::GO:0006897; P:endocytosis; IDA:MGI. | 66 | Q4V8H8 | 543 | EHD2_RAT EH domain-containing protein 2 OS=Ra... | 85 | 0.00000006 | 57 | 41 | 54 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0032456; P:endocytic recycling; ISS:UniProtKB. | 67 | O42287 | 1270 | ITSN1_XENLA Intersectin-1 OS=Xenopus laevis (... | 127 | 0.41 | 36.2 | 20 | 44 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 68 | Q10172 | 1794 | PAN1_SCHPO Actin cytoskeleton-regulatory comp... | 127 | 0.031 | 39.7 | 24 | 46 | GO:0030479; C:actin cortical patch; ISS:PomBase.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0000147; P:actin cortical patch assembly; ISS:PomBase.::GO:0006897; P:endocytosis; ISS:PomBase.::GO:0006886; P:intracellular protein transport; IC:PomBase. | 69 | Q9HGL2 | 1116 | YHLA_SCHPO Uncharacterized calcium-binding pr... | 47 | 0.000006 | 51.2 | 45 | 66 | GO:0030479; C:actin cortical patch; ISS:PomBase. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0000147; P:actin cortical patch assembly; ISS:PomBase.::GO:0006886; P:intracellular protein transport; IC:PomBase.::GO:0006898; P:receptor-mediated endocytosis; ISS:PomBase. | 70 | Q5RBP4 | 534 | EHD1_PONAB EH domain-containing protein 1 OS=... | 93 | 7.6 | 32 | 23 | 48 | GO:0031901; C:early endosome membrane; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0032456; P:endocytic recycling; ISS:UniProtKB.::GO:0006886; P:intracellular protein transport; ISS:UniProtKB. | 71 | Q9H4M9 | 534 | EHD1_HUMAN EH domain-containing protein 1 OS=... | 93 | 7.6 | 32 | 23 | 48 | GO:0031901; C:early endosome membrane; IDA:UniProtKB.::GO:0005811; C:lipid particle; ISS:BHF-UCL.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0031095; C:platelet dense tubular network membrane; ISS:BHF-UCL.::GO:0055038; C:recycling endosome membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0042632; P:cholesterol homeostasis; ISS:BHF-UCL.::GO:0032456; P:endocytic recycling; IMP:UniProtKB.::GO:0006886; P:intracellular protein transport; IMP:UniProtKB.::GO:0034383; P:low-density lipoprotein particle clearance; ISS:BHF-UCL.::GO:0010886; P:positive regulation of cholesterol storage; ISS:BHF-UCL.::GO:0051260; P:protein homooligomerization; IPI:UniProtKB. | 72 | Q9NZN4 | 543 | EHD2_HUMAN EH domain-containing protein 2 OS=... | 85 | 0.0000002 | 55.5 | 40 | 53 | GO:0005634; C:nucleus; TAS:ProtInc.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0055038; C:recycling endosome membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; TAS:ProtInc. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0032456; P:endocytic recycling; IGI:UniProtKB. | 73 | A5DVD6 | 1505 | PAN1_LODEL Actin cytoskeleton-regulatory comp... | 89 | 5 | 32.7 | 22 | 43 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 74 | Q641Z6 | 534 | EHD1_RAT EH domain-containing protein 1 OS=Ra... | 93 | 7 | 32 | 23 | 48 | GO:0031901; C:early endosome membrane; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0032456; P:endocytic recycling; ISS:UniProtKB.::GO:0006886; P:intracellular protein transport; ISS:UniProtKB. | 75 | Q9WVK4 | 534 | EHD1_MOUSE EH domain-containing protein 1 OS=... | 93 | 7 | 32 | 23 | 48 | GO:0031901; C:early endosome membrane; ISS:UniProtKB.::GO:0030139; C:endocytic vesicle; IDA:MGI.::GO:0005811; C:lipid particle; IDA:BHF-UCL.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0031095; C:platelet dense tubular network membrane; IDA:BHF-UCL.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0042632; P:cholesterol homeostasis; IMP:BHF-UCL.::GO:0032456; P:endocytic recycling; ISS:UniProtKB.::GO:0006897; P:endocytosis; IDA:MGI.::GO:0006886; P:intracellular protein transport; ISS:UniProtKB.::GO:0034383; P:low-density lipoprotein particle clearance; IMP:BHF-UCL.::GO:0010886; P:positive regulation of cholesterol storage; IMP:BHF-UCL. | 76 | Q5E9R3 | 534 | EHD1_BOVIN EH domain-containing protein 1 OS=... | 93 | 9.5 | 31.6 | 23 | 48 | GO:0031901; C:early endosome membrane; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0032456; P:endocytic recycling; ISS:UniProtKB.::GO:0006886; P:intracellular protein transport; ISS:UniProtKB. | 77 | O94685 | 884 | UCP8_SCHPO UBA domain-containing protein 8 OS... | 69 | 1 | 34.7 | 28 | 55 | GO:0030479; C:actin cortical patch; ISS:PomBase. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0031593; F:polyubiquitin binding; TAS:PomBase. | | | | | | | | | | GO:0000147; P:actin cortical patch assembly; ISS:PomBase.::GO:0006886; P:intracellular protein transport; IC:PomBase.::GO:0006898; P:receptor-mediated endocytosis; NAS:PomBase. | 78 | Q8NFH8 | 660 | REPS2_HUMAN RalBP1-associated Eps domain-cont... | 93 | 0.000001 | 53.5 | 35 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:ProtInc.::GO:0006461; P:protein complex assembly; TAS:ProtInc. | 79 | Q9Z0R6 | 1659 | ITSN2_MOUSE Intersectin-2 OS=Mus musculus (Mo... | 49 | 0.00003 | 49.3 | 49 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 80 | Q80XA6 | 521 | REPS2_MOUSE RalBP1-associated Eps domain-cont... | 93 | 0.000001 | 53.1 | 35 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | | 81 | Q8R491 | 535 | EHD3_RAT EH domain-containing protein 3 OS=Ra... | 86 | 0.000002 | 52.8 | 37 | 53 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; ISS:UniProtKB. | | | | | | | | | | GO:0032456; P:endocytic recycling; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB. | 82 | Q9QXY6 | 535 | EHD3_MOUSE EH domain-containing protein 3 OS=... | 86 | 0.000002 | 52.4 | 37 | 53 | GO:0030139; C:endocytic vesicle; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0032456; P:endocytic recycling; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB. | 83 | Q9NZM3 | 1697 | ITSN2_HUMAN Intersectin-2 OS=Homo sapiens (Hu... | 49 | 0.00002 | 49.7 | 51 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 84 | P34216 | 1381 | EDE1_YEAST EH domain-containing and endocytos... | 234 | 0.0002 | 46.6 | 21 | 39 | GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IDA:SGD. | | | | | | | | | | GO:0006897; P:endocytosis; IMP:SGD.::GO:0030968; P:endoplasmic reticulum unfolded protein response; IMP:SGD. | 85 | Q9NZN3 | 535 | EHD3_HUMAN EH domain-containing protein 3 OS=... | 86 | 0.00001 | 50.4 | 36 | 52 | GO:0005634; C:nucleus; TAS:ProtInc.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0055038; C:recycling endosome membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0032456; P:endocytic recycling; IDA:UniProtKB.::GO:0051260; P:protein homooligomerization; IPI:UniProtKB. | 86 | O54916 | 795 | REPS1_MOUSE RalBP1-associated Eps domain-cont... | 69 | 6.1 | 32.3 | 25 | 45 | | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | | 87 | Q96D71 | 796 | REPS1_HUMAN RalBP1-associated Eps domain-cont... | 69 | 5.5 | 32.3 | 25 | 45 | GO:0005905; C:coated pit; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IPI:UniProtKB. | | | | | | | | | | | 88 | Q9H223 | 541 | EHD4_HUMAN EH domain-containing protein 4 OS=... | 108 | 0.62 | 35.4 | 22 | 48 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IDA:LIFEdb.::GO:0005634; C:nucleus; TAS:ProtInc.::GO:0055038; C:recycling endosome membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0032456; P:endocytic recycling; IGI:UniProtKB.::GO:0051260; P:protein homooligomerization; IPI:UniProtKB. | 89 | Q9EQP2 | 541 | EHD4_MOUSE EH domain-containing protein 4 OS=... | 108 | 0.67 | 35 | 22 | 48 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0032456; P:endocytic recycling; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB. | 90 | Q9C6P3 | 521 | CDPKX_ARATH Calcium-dependent protein kinase ... | 72 | 0.52 | 35.4 | 32 | 58 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 91 | Q9HFY6 | 149 | CALM_BLAEM Calmodulin OS=Blastocladiella emer... | 65 | 0.005 | 40 | 34 | 57 | | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | |
