rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | A4R596 | 1874 | IML1_MAGO7 Vacuolar membrane-associated prote... | 1931 | 0 | 2550 | 67 | 78 | GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 2 | Q7S9J6 | 2004 | IML1_NEUCR Vacuolar membrane-associated prote... | 1872 | 0 | 2084 | 58 | 70 | GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 3 | Q2H0S0 | 1889 | IML1_CHAGB Vacuolar membrane-associated prote... | 1869 | 0 | 2071 | 58 | 70 | GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 4 | Q2UMR9 | 1824 | IML1_ASPOR Vacuolar membrane-associated prote... | 1875 | 0 | 1072 | 37 | 52 | GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 5 | Q4WHH4 | 1836 | IML1_ASPFU Vacuolar membrane-associated prote... | 1843 | 0 | 1069 | 37 | 54 | GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 6 | Q0CHV5 | 1830 | IML1_ASPTN Vacuolar membrane-associated prote... | 1874 | 0 | 1066 | 37 | 53 | GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 7 | Q1E9Q9 | 1857 | IML1_COCIM Vacuolar membrane-associated prote... | 1886 | 0 | 1066 | 36 | 54 | GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 8 | Q5AW24 | 1831 | IML1_EMENI Vacuolar membrane-associated prote... | 1899 | 0 | 1054 | 36 | 52 | GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 9 | A1CEE0 | 1845 | IML1_ASPCL Vacuolar membrane-associated prote... | 1872 | 0 | 1053 | 37 | 53 | GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 10 | A1DFV9 | 1842 | IML1_NEOFI Vacuolar membrane-associated prote... | 592 | 5e-115 | 408 | 39 | 58 | GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 11 | Q5AIA4 | 1462 | IML1_CANAL Vacuolar membrane-associated prote... | 316 | 5e-46 | 186 | 32 | 52 | GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 12 | A3LRB2 | 1489 | IML1_PICST Vacuolar membrane-associated prote... | 319 | 2e-47 | 191 | 34 | 53 | GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 13 | O74788 | 1496 | IML1_SCHPO Vacuolar membrane-associated prote... | 533 | 9e-73 | 273 | 32 | 52 | GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 14 | Q6BN00 | 1560 | IML1_DEBHA Vacuolar membrane-associated prote... | 319 | 8e-45 | 182 | 32 | 53 | GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 15 | Q6CAP3 | 1547 | IML1_YARLI Vacuolar membrane-associated prote... | 316 | 4e-58 | 226 | 38 | 57 | GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 16 | P47170 | 1584 | IML1_YEAST Vacuolar membrane-associated prote... | 393 | 6e-52 | 206 | 30 | 50 | GO:0097042; C:extrinsic to fungal-type vacuolar membrane; IDA:SGD.::GO:0035859; C:Seh1-associated complex; IDA:SGD. | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 17 | Q6FK84 | 1804 | IML1_CANGA Vacuolar membrane-associated prote... | 454 | 4e-50 | 200 | 28 | 44 | GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 18 | Q6CWI2 | 1558 | IML1_KLULA Vacuolar membrane-associated prote... | 370 | 2e-49 | 197 | 30 | 52 | GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 19 | Q4PE51 | 1867 | IML1_USTMA Vacuolar membrane-associated prote... | 578 | 9e-76 | 284 | 32 | 52 | GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 20 | Q75DV2 | 1534 | IML1_ASHGO Vacuolar membrane-associated prote... | 320 | 2e-45 | 184 | 33 | 52 | GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 21 | Q54XA2 | 2242 | Y9099_DICDI DEP domain-containing protein DDB... | 102 | 0.011 | 44.7 | 27 | 46 | | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 22 | O75140 | 1572 | DEPD5_HUMAN DEP domain-containing protein 5 O... | 380 | 0.0000000002 | 69.7 | 24 | 42 | | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 23 | P0CO32 | 1768 | IML1_CRYNJ Vacuolar membrane-associated prote... | 46 | 1.9 | 37.4 | 41 | 52 | GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 24 | P0CO33 | 1768 | IML1_CRYNB Vacuolar membrane-associated prote... | 46 | 1.9 | 37.4 | 41 | 52 | GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 25 | P61460 | 1527 | DEPD5_MOUSE DEP domain-containing protein 5 O... | 393 | 0.00000000005 | 72 | 24 | 39 | | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 26 | P51140 | 623 | DSH_DROME Segment polarity protein dishevelle... | 82 | 0.0005 | 48.5 | 29 | 57 | GO:0005912; C:adherens junction; TAS:FlyBase.::GO:0005938; C:cell cortex; IBA:RefGenome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:FlyBase. | | | | | | | | | | GO:0005112; F:Notch binding; NAS:FlyBase.::GO:0070300; F:phosphatidic acid binding; IDA:FlyBase.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0048675; P:axon extension; IMP:FlyBase.::GO:0007298; P:border follicle cell migration; IMP:FlyBase.::GO:0007394; P:dorsal closure, elongation of leading edge cells; IMP:FlyBase.::GO:0048730; P:epidermis morphogenesis; IMP:FlyBase.::GO:0045198; P:establishment of epithelial cell apical/basal polarity; IMP:FlyBase.::GO:0090163; P:establishment of epithelial cell planar polarity; IMP:FlyBase.::GO:0001737; P:establishment of imaginal disc-derived wing hair orientation; IMP:FlyBase.::GO:0048106; P:establishment of thoracic bristle planar orientation; TAS:FlyBase.::GO:0008585; P:female gonad development; IMP:FlyBase.::GO:0046847; P:filopodium assembly; IMP:FlyBase.::GO:0060914; P:heart formation; IMP:FlyBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0030032; P:lamellipodium assembly; IMP:FlyBase.::GO:0003136; P:negative regulation of heart induction by canonical Wnt receptor signaling pathway; IMP:FlyBase.::GO:0016318; P:ommatidial rotation; NAS:FlyBase.::GO:0008104; P:protein localization; TAS:FlyBase.::GO:0007464; P:R3/R4 cell fate commitment; NAS:FlyBase.::GO:0032231; P:regulation of actin filament bundle assembly; IGI:FlyBase.::GO:0048076; P:regulation of compound eye pigmentation; IMP:FlyBase.::GO:0035159; P:regulation of tube length, open tracheal system; IMP:FlyBase.::GO:0031290; P:retinal ganglion cell axon guidance; IMP:FlyBase.::GO:0007435; P:salivary gland morphogenesis; IMP:FlyBase.::GO:0007367; P:segment polarity determination; IEA:UniProtKB-KW.::GO:0035019; P:somatic stem cell maintenance; IMP:FlyBase.::GO:0035309; P:wing and notum subfield formation; IMP:FlyBase.::GO:0060071; P:Wnt receptor signaling pathway, planar cell polarity pathway; IBA:RefGenome. | 27 | Q05AS8 | 732 | DVL2_XENTR Segment polarity protein dishevell... | 64 | 0.001 | 47.4 | 33 | 59 | GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0035253; C:ciliary rootlet; ISS:UniProtKB.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0046875; F:ephrin receptor binding; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0045545; F:syndecan binding; ISS:UniProtKB. | | | | | | | | | | GO:0032862; P:activation of Rho GTPase activity; ISS:UniProtKB.::GO:0009948; P:anterior/posterior axis specification; ISS:UniProtKB.::GO:0042384; P:cilium assembly; ISS:UniProtKB.::GO:0060027; P:convergent extension involved in gastrulation; ISS:UniProtKB.::GO:0009950; P:dorsal/ventral axis specification; ISS:UniProtKB.::GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0001736; P:establishment of planar polarity; ISS:UniProtKB.::GO:0007163; P:establishment or maintenance of cell polarity; ISS:UniProtKB.::GO:0001702; P:gastrulation with mouth forming second; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0032053; P:microtubule basal body organization; ISS:UniProtKB.::GO:0001843; P:neural tube closure; ISS:UniProtKB.::GO:0022008; P:neurogenesis; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.::GO:0050821; P:protein stabilization; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; ISS:UniProtKB. | 28 | Q8WZA2 | 1011 | RPGF4_HUMAN Rap guanine nucleotide exchange f... | 97 | 0.002 | 47.4 | 22 | 46 | GO:0005952; C:cAMP-dependent protein kinase complex; IEA:InterPro.::GO:0005624; C:membrane fraction; TAS:ProtInc. | | | | | | | | | | GO:0030552; F:cAMP binding; ISS:UniProtKB.::GO:0008603; F:cAMP-dependent protein kinase regulator activity; IEA:InterPro.::GO:0017016; F:Ras GTPase binding; ISS:UniProtKB.::GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.::GO:0001932; P:regulation of protein phosphorylation; IEA:InterPro.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 29 | Q61062 | 716 | DVL3_MOUSE Segment polarity protein dishevell... | 64 | 0.002 | 47 | 34 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 30 | Q92997 | 716 | DVL3_HUMAN Segment polarity protein dishevell... | 64 | 0.002 | 47 | 34 | 58 | GO:0005938; C:cell cortex; IBA:RefGenome. | | | | | | | | | | GO:0008013; F:beta-catenin binding; IDA:BHF-UCL.::GO:0005109; F:frizzled binding; IPI:UniProtKB.::GO:0002020; F:protease binding; IPI:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IDA:BHF-UCL.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0060070; P:canonical Wnt receptor signaling pathway; IDA:BHF-UCL.::GO:0090103; P:cochlea morphogenesis; IBA:RefGenome.::GO:0060026; P:convergent extension; IBA:RefGenome.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0003148; P:outflow tract septum morphogenesis; IBA:RefGenome.::GO:0090179; P:planar cell polarity pathway involved in neural tube closure; IBA:RefGenome.::GO:0043507; P:positive regulation of JUN kinase activity; IMP:BHF-UCL.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:BHF-UCL.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:BHF-UCL. | 31 | Q9EQZ6 | 1011 | RPGF4_MOUSE Rap guanine nucleotide exchange f... | 97 | 0.011 | 44.7 | 21 | 45 | GO:0005952; C:cAMP-dependent protein kinase complex; IEA:InterPro.::GO:0005829; C:cytosol; IDA:MGI. | | | | | | | | | | GO:0030552; F:cAMP binding; IDA:UniProtKB.::GO:0008603; F:cAMP-dependent protein kinase regulator activity; IEA:InterPro.::GO:0017016; F:Ras GTPase binding; IPI:UniProtKB.::GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; IDA:UniProtKB. | | | | | | | | | | GO:0017156; P:calcium ion-dependent exocytosis; IDA:MGI.::GO:0019933; P:cAMP-mediated signaling; IDA:MGI.::GO:0030073; P:insulin secretion; IDA:MGI.::GO:0017157; P:regulation of exocytosis; IDA:MGI.::GO:0001932; P:regulation of protein phosphorylation; IEA:InterPro.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. |