| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
361 | Q92KY8 | 370 | LEU3_RHIME 3-isopropylmalate dehydrogenase OS... | 363 | 4e-24 | 105 | 31 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 362 | Q96WT9 | 365 | LEU3_SACEX 3-isopropylmalate dehydrogenase OS... | 352 | 5e-24 | 105 | 28 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 363 | P41926 | 368 | LEU3_KODOH 3-isopropylmalate dehydrogenase OS... | 369 | 7e-24 | 104 | 28 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 364 | O14429 | 365 | LEU3_CANGA 3-isopropylmalate dehydrogenase OS... | 359 | 9e-24 | 103 | 28 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 365 | Q6PY58 | 363 | LEU3_CANMI 3-isopropylmalate dehydrogenase OS... | 358 | 1e-23 | 103 | 28 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 366 | P08791 | 363 | LEU3_CYBJA 3-isopropylmalate dehydrogenase OS... | 361 | 2e-23 | 102 | 28 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 367 | Q1QAF5 | 367 | LEU3_PSYCK 3-isopropylmalate dehydrogenase OS... | 314 | 2e-23 | 102 | 30 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 368 | P87186 | 373 | LEU3_CANAX 3-isopropylmalate dehydrogenase OS... | 370 | 7e-23 | 101 | 26 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 369 | Q00412 | 355 | LEU3_SPIPL 3-isopropylmalate dehydrogenase OS... | 342 | 7e-23 | 101 | 31 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 370 | P86225 | 134 | IDH3A_MESAU Isocitrate dehydrogenase [NAD] su... | 105 | 1e-22 | 96.7 | 50 | 62 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 371 | P41766 | 359 | LEU3_KLUMA 3-isopropylmalate dehydrogenase OS... | 265 | 3e-22 | 99.8 | 30 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 372 | Q3Z896 | 365 | LEU3_DEHE1 3-isopropylmalate dehydrogenase OS... | 223 | 7e-22 | 99 | 32 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 373 | Q8NKB8 | 362 | LEU3_BLAAD 3-isopropylmalate dehydrogenase OS... | 355 | 1e-21 | 97.8 | 28 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 374 | P80046 | 475 | IDH_SYNY3 Isocitrate dehydrogenase [NADP] OS=... | 176 | 1e-16 | 84.7 | 33 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 375 | O94114 | 373 | LEU3_PICST 3-isopropylmalate dehydrogenase OS... | 363 | 1e-20 | 95.1 | 26 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 376 | Q9AQC8 | 126 | LEU3_BUCUL 3-isopropylmalate dehydrogenase OS... | 92 | 0.00000000000001 | 74.3 | 42 | 65 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 377 | P56471 | 90 | IDH3A_PIG Isocitrate dehydrogenase [NAD] subu... | 34 | 0.000003 | 49.7 | 71 | 79 | GO:0005739; C:mitochondrion; IDA:UniProtKB. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IDA:UniProtKB. | 378 | O13285 | 430 | IDH1_CANTR Isocitrate dehydrogenase [NADP], m... | 169 | 0.00008 | 48.1 | 27 | 47 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006102; P:isocitrate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 379 | P21954 | 428 | IDHP_YEAST Isocitrate dehydrogenase [NADP], m... | 170 | 0.0001 | 47.4 | 26 | 43 | GO:0042645; C:mitochondrial nucleoid; IDA:SGD. | | | | | | | | | | GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; TAS:SGD.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006537; P:glutamate biosynthetic process; IMP:SGD.::GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006102; P:isocitrate metabolic process; TAS:SGD.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 380 | P79089 | 498 | IDHP_ASPNG Isocitrate dehydrogenase [NADP], m... | 195 | 0.0005 | 45.4 | 26 | 42 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006102; P:isocitrate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 381 | P53982 | 420 | IDHH_YEAST Isocitrate dehydrogenase [NADP] OS... | 182 | 0.0007 | 45.1 | 27 | 40 | GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005777; C:peroxisome; IDA:SGD. | | | | | | | | | | GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; TAS:SGD.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006635; P:fatty acid beta-oxidation; IMP:SGD.::GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006102; P:isocitrate metabolic process; TAS:SGD.::GO:0006740; P:NADPH regeneration; TAS:SGD.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 382 | O13294 | 411 | IDH2_CANTR Isocitrate dehydrogenase [NADP] pe... | 169 | 0.003 | 43.1 | 27 | 43 | GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006102; P:isocitrate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 383 | Q4R502 | 452 | IDHP_MACFA Isocitrate dehydrogenase [NADP], m... | 428 | 0.004 | 42.7 | 24 | 38 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006103; P:2-oxoglutarate metabolic process; ISS:UniProtKB.::GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 384 | P33198 | 421 | IDHP_PIG Isocitrate dehydrogenase [NADP], mit... | 171 | 0.004 | 42.7 | 27 | 42 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006103; P:2-oxoglutarate metabolic process; ISS:UniProtKB.::GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 385 | P41939 | 412 | IDHC_YEAST Isocitrate dehydrogenase [NADP] cy... | 181 | 0.005 | 42.4 | 28 | 42 | GO:0005829; C:cytosol; IDA:SGD. | | | | | | | | | | GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; TAS:SGD.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006537; P:glutamate biosynthetic process; TAS:SGD.::GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006102; P:isocitrate metabolic process; IMP:SGD.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 386 | P56574 | 452 | IDHP_RAT Isocitrate dehydrogenase [NADP], mit... | 171 | 0.005 | 42.4 | 27 | 41 | | | | | | | | | | | GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006103; P:2-oxoglutarate metabolic process; ISS:UniProtKB.::GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 387 | P48735 | 452 | IDHP_HUMAN Isocitrate dehydrogenase [NADP], m... | 171 | 0.009 | 41.6 | 27 | 42 | GO:0005759; C:mitochondrial matrix; TAS:Reactome. | | | | | | | | | | GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006103; P:2-oxoglutarate metabolic process; ISS:UniProtKB.::GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; TAS:Reactome. | 388 | Q04467 | 452 | IDHP_BOVIN Isocitrate dehydrogenase [NADP], m... | 171 | 0.01 | 41.6 | 27 | 42 | GO:0005743; C:mitochondrial inner membrane; ISS:AgBase. | | | | | | | | | | GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006103; P:2-oxoglutarate metabolic process; ISS:UniProtKB.::GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 389 | P54071 | 452 | IDHP_MOUSE Isocitrate dehydrogenase [NADP], m... | 171 | 0.011 | 41.2 | 27 | 41 | GO:0005743; C:mitochondrial inner membrane; IDA:MGI. | | | | | | | | | | GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006103; P:2-oxoglutarate metabolic process; ISS:UniProtKB.::GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 390 | O14254 | 439 | IDHP_SCHPO Probable isocitrate dehydrogenase ... | 210 | 0.034 | 39.7 | 26 | 41 | GO:0005739; C:mitochondrion; IDA:PomBase. | | | | | | | | | | GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; ISS:PomBase.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006537; P:glutamate biosynthetic process; ISS:PomBase.::GO:0006102; P:isocitrate metabolic process; ISS:PomBase.::GO:0006740; P:NADPH regeneration; ISS:PomBase.::GO:0006099; P:tricarboxylic acid cycle; IC:PomBase. | 391 | P50215 | 406 | IDH_SPHYA Isocitrate dehydrogenase [NADP] OS=... | 179 | 0.042 | 39.3 | 30 | 42 | | | | | | | | | | | GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006102; P:isocitrate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. |
