| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
271 | Q9LT96 | 946 | Y5977_ARATH Probable leucine-rich repeat rece... | 161 | 0.0007 | 47.8 | 26 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 272 | P0C8E4 | 606 | M3K7_RAT Mitogen-activated protein kinase kin... | 194 | 0.0007 | 47.4 | 23 | 43 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:RGD. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007252; P:I-kappaB phosphorylation; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:RGD.::GO:0043507; P:positive regulation of JUN kinase activity; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 273 | Q1KL86 | 976 | EPHA2_MACFA Ephrin type-A receptor 2 OS=Macac... | 231 | 0.0007 | 47.8 | 21 | 38 | GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.::GO:0031258; C:lamellipodium membrane; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005003; F:ephrin receptor activity; IEA:InterPro. | | | | | | | | | | GO:0032863; P:activation of Rac GTPase activity; ISS:UniProtKB.::GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0046849; P:bone remodeling; ISS:UniProtKB.::GO:0060444; P:branching involved in mammary gland duct morphogenesis; ISS:UniProtKB.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0060326; P:cell chemotaxis; ISS:UniProtKB.::GO:0070309; P:lens fiber cell morphogenesis; ISS:UniProtKB.::GO:0033598; P:mammary gland epithelial cell proliferation; ISS:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0001649; P:osteoblast differentiation; ISS:UniProtKB.::GO:0030316; P:osteoclast differentiation; ISS:UniProtKB.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0045765; P:regulation of angiogenesis; ISS:UniProtKB.::GO:0033628; P:regulation of cell adhesion mediated by integrin; ISS:UniProtKB.::GO:0010591; P:regulation of lamellipodium assembly; ISS:UniProtKB.::GO:0070848; P:response to growth factor stimulus; ISS:UniProtKB. | 274 | O80623 | 815 | Y2393_ARATH Probable receptor-like protein ki... | 137 | 0.0007 | 47.8 | 30 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 275 | O13146 | 981 | EPHA3_DANRE Ephrin type-A receptor 3 OS=Danio... | 316 | 0.0007 | 47.8 | 24 | 39 | GO:0005769; C:early endosome; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005004; F:GPI-linked ephrin receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0097156; P:fasciculation of motor neuron axon; ISS:UniProtKB.::GO:0097155; P:fasciculation of sensory neuron axon; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0010717; P:regulation of epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0051893; P:regulation of focal adhesion assembly; ISS:UniProtKB.::GO:0070507; P:regulation of microtubule cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB. | 276 | P17713 | 509 | STK_HYDVU Tyrosine-protein kinase STK OS=Hydr... | 188 | 0.0007 | 47.4 | 22 | 41 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 277 | Q64725 | 629 | KSYK_RAT Tyrosine-protein kinase SYK OS=Rattu... | 224 | 0.0008 | 47.4 | 21 | 38 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0032009; C:early phagosome; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; ISS:UniProtKB.::GO:0019904; F:protein domain specific binding; IMP:RGD. | | | | | | | | | | GO:0002250; P:adaptive immune response; ISS:UniProtKB.::GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0071226; P:cellular response to molecule of fungal origin; ISS:UniProtKB.::GO:0042742; P:defense response to bacterium; ISS:UniProtKB.::GO:0045087; P:innate immune response; ISS:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; ISS:UniProtKB.::GO:0007159; P:leukocyte cell-cell adhesion; ISS:UniProtKB.::GO:0001945; P:lymph vessel development; ISS:UniProtKB.::GO:0002281; P:macrophage activation involved in immune response; ISS:UniProtKB.::GO:0002283; P:neutrophil activation involved in immune response; ISS:UniProtKB.::GO:0030593; P:neutrophil chemotaxis; ISS:UniProtKB.::GO:0045780; P:positive regulation of bone resorption; ISS:UniProtKB.::GO:0033630; P:positive regulation of cell adhesion mediated by integrin; ISS:UniProtKB.::GO:0043306; P:positive regulation of mast cell degranulation; IMP:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0090237; P:regulation of arachidonic acid secretion; ISS:UniProtKB.::GO:0070372; P:regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0043313; P:regulation of neutrophil degranulation; ISS:UniProtKB.::GO:0050764; P:regulation of phagocytosis; ISS:UniProtKB.::GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB.::GO:0032928; P:regulation of superoxide anion generation; ISS:UniProtKB.::GO:0002554; P:serotonin secretion by platelet; ISS:UniProtKB. | 278 | Q9FJ54 | 439 | CIPKK_ARATH CBL-interacting serine/threonine-... | 222 | 0.0008 | 47 | 21 | 42 | GO:0005829; C:cytosol; TAS:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:TAIR. | | | | | | | | | | GO:0009737; P:response to abscisic acid stimulus; IMP:TAIR.::GO:0007165; P:signal transduction; IEA:InterPro. | 279 | Q24592 | 1177 | JAK_DROME Tyrosine-protein kinase hopscotch O... | 160 | 0.0008 | 47.8 | 24 | 40 | GO:0005737; C:cytoplasm; TAS:FlyBase.::GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0003383; P:apical constriction; IMP:FlyBase.::GO:0007298; P:border follicle cell migration; IMP:FlyBase.::GO:0006968; P:cellular defense response; NAS:FlyBase.::GO:0001751; P:compound eye photoreceptor cell differentiation; IMP:FlyBase.::GO:0000910; P:cytokinesis; TAS:FlyBase.::GO:0051607; P:defense response to virus; IMP:FlyBase.::GO:0035010; P:encapsulation of foreign target; NAS:FlyBase.::GO:0045317; P:equator specification; IMP:FlyBase.::GO:0007455; P:eye-antennal disc morphogenesis; IMP:FlyBase.::GO:0042078; P:germ-line stem cell division; TAS:FlyBase.::GO:0035172; P:hemocyte proliferation; TAS:FlyBase.::GO:0007442; P:hindgut morphogenesis; IMP:FlyBase.::GO:0006959; P:humoral immune response; TAS:FlyBase.::GO:0007480; P:imaginal disc-derived leg morphogenesis; NAS:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; NAS:FlyBase.::GO:0035171; P:lamellocyte differentiation; TAS:FlyBase.::GO:0007616; P:long-term memory; IMP:FlyBase.::GO:0060031; P:mediolateral intercalation; IMP:FlyBase.::GO:0016318; P:ommatidial rotation; IMP:FlyBase.::GO:0007424; P:open tracheal system development; IMP:FlyBase.::GO:0030713; P:ovarian follicle cell stalk formation; IMP:FlyBase.::GO:0007365; P:periodic partitioning; IMP:FlyBase.::GO:0007538; P:primary sex determination; IMP:FlyBase.::GO:0016476; P:regulation of embryonic cell shape; IMP:FlyBase.::GO:0045610; P:regulation of hemocyte differentiation; IMP:FlyBase.::GO:0046425; P:regulation of JAK-STAT cascade; IMP:FlyBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0048103; P:somatic stem cell division; TAS:FlyBase.::GO:0007262; P:STAT protein import into nucleus; TAS:FlyBase.::GO:0019827; P:stem cell maintenance; IMP:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007260; P:tyrosine phosphorylation of STAT protein; TAS:FlyBase. | 280 | Q03497 | 939 | STE20_YEAST Serine/threonine-protein kinase S... | 217 | 0.0008 | 47.4 | 25 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000131; C:incipient cellular bud site; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035174; F:histone serine kinase activity; IDA:SGD.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0008349; F:MAP kinase kinase kinase kinase activity; IDA:SGD. | | | | | | | | | | GO:0000282; P:cellular bud site selection; IMP:SGD.::GO:0034605; P:cellular response to heat; IMP:SGD.::GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD.::GO:0010629; P:negative regulation of gene expression; IMP:SGD.::GO:0007232; P:osmosensory signaling pathway via Sho1 osmosensor; IMP:SGD.::GO:0000750; P:pheromone-dependent signal transduction involved in conjugation with cellular fusion; IMP:SGD.::GO:0043065; P:positive regulation of apoptotic process; IMP:SGD.::GO:0007124; P:pseudohyphal growth; IMP:SGD.::GO:0007096; P:regulation of exit from mitosis; IMP:SGD.::GO:0001402; P:signal transduction involved in filamentous growth; IMP:SGD.::GO:0035376; P:sterol import; IMP:SGD.::GO:0034063; P:stress granule assembly; IMP:SGD.::GO:0000011; P:vacuole inheritance; IMP:SGD. | 281 | O09127 | 1004 | EPHA8_MOUSE Ephrin type-A receptor 8 OS=Mus m... | 228 | 0.0009 | 47.4 | 19 | 37 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0043005; C:neuron projection; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005004; F:GPI-linked ephrin receptor activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; IMP:UniProtKB.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0016322; P:neuron remodeling; IDA:UniProtKB.::GO:0043410; P:positive regulation of MAPK cascade; IDA:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0033628; P:regulation of cell adhesion mediated by integrin; IDA:UniProtKB.::GO:0006929; P:substrate-dependent cell migration; IDA:UniProtKB. | 282 | Q55E58 | 3184 | PATS1_DICDI Probable serine/threonine-protein... | 277 | 0.0009 | 47.8 | 21 | 42 | GO:0042641; C:actomyosin; IPI:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:dictyBase. | | | | | | | | | | GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 283 | B2GUY1 | 924 | PLK4_RAT Serine/threonine-protein kinase PLK4... | 178 | 0.0009 | 47.4 | 25 | 41 | GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007099; P:centriole replication; ISS:UniProtKB.::GO:0046601; P:positive regulation of centriole replication; ISS:UniProtKB.::GO:0060707; P:trophoblast giant cell differentiation; ISS:UniProtKB. | 284 | Q5GIG6 | 834 | TNI3K_MOUSE Serine/threonine-protein kinase T... | 233 | 0.0009 | 47.4 | 22 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 285 | P50527 | 658 | STE20_SCHPO Serine/threonine-protein kinase s... | 250 | 0.0009 | 47.4 | 22 | 36 | GO:0071521; C:Cdc42 GTPase complex; TAS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase. | | | | | | | | | | GO:0032488; P:Cdc42 protein signal transduction; IGI:PomBase.::GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; TAS:PomBase.::GO:0061161; P:positive regulation of establishment of bipolar cell polarity regulating cell shape; IGI:PomBase.::GO:0071775; P:regulation of cell cycle cytokinesis; IMP:PomBase.::GO:0070507; P:regulation of microtubule cytoskeleton organization; IGI:PomBase. | 286 | P42684 | 1182 | ABL2_HUMAN Abelson tyrosine-protein kinase 2 ... | 230 | 0.0009 | 47.4 | 19 | 38 | GO:0015629; C:actin cytoskeleton; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0051015; F:actin filament binding; TAS:UniProtKB.::GO:0003785; F:actin monomer binding; TAS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0030145; F:manganese ion binding; IDA:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0071300; P:cellular response to retinoic acid; IMP:BHF-UCL.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; IMP:BHF-UCL.::GO:0051353; P:positive regulation of oxidoreductase activity; IDA:BHF-UCL.::GO:2000249; P:regulation of actin cytoskeleton reorganization; TAS:UniProtKB.::GO:0010506; P:regulation of autophagy; TAS:UniProtKB.::GO:0030155; P:regulation of cell adhesion; TAS:UniProtKB.::GO:2000145; P:regulation of cell motility; TAS:UniProtKB.::GO:0030100; P:regulation of endocytosis; TAS:UniProtKB.::GO:0007165; P:signal transduction; TAS:ProtInc. | 287 | O18735 | 1259 | ERBB2_CANFA Receptor tyrosine-protein kinase ... | 234 | 0.001 | 47.4 | 22 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004716; F:receptor signaling protein tyrosine kinase activity; IEA:InterPro.::GO:0001042; F:RNA polymerase I core binding; ISS:UniProtKB.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0045943; P:positive regulation of transcription from RNA polymerase I promoter; ISS:UniProtKB.::GO:0045945; P:positive regulation of transcription from RNA polymerase III promoter; ISS:UniProtKB.::GO:0045727; P:positive regulation of translation; ISS:UniProtKB.::GO:0070372; P:regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0032886; P:regulation of microtubule-based process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 288 | C0LGQ5 | 1249 | GSO1_ARATH LRR receptor-like serine/threonine... | 215 | 0.001 | 47.4 | 23 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009790; P:embryo development; IGI:TAIR.::GO:0008544; P:epidermis development; IGI:TAIR. | 289 | P20689 | 610 | MYLK2_RAT Myosin light chain kinase 2, skelet... | 168 | 0.001 | 47 | 25 | 45 | GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0014069; C:postsynaptic density; IDA:RGD.::GO:0008021; C:synaptic vesicle; IDA:RGD.::GO:0043195; C:terminal button; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0032027; F:myosin light chain binding; IMP:RGD.::GO:0004687; F:myosin light chain kinase activity; IDA:RGD. | | | | | | | | | | GO:0018105; P:peptidyl-serine phosphorylation; TAS:RGD.::GO:0051272; P:positive regulation of cellular component movement; IMP:RGD.::GO:0031448; P:positive regulation of fast-twitch skeletal muscle fiber contraction; IMP:RGD.::GO:0051726; P:regulation of cell cycle; IMP:RGD.::GO:0043408; P:regulation of MAPK cascade; IMP:RGD.::GO:0048168; P:regulation of neuronal synaptic plasticity; IMP:RGD.::GO:0048489; P:synaptic vesicle transport; IMP:RGD.::GO:0006833; P:water transport; IMP:RGD. | 290 | O75011 | 652 | NAK1_SCHPO Serine/threonine-protein kinase na... | 231 | 0.001 | 47 | 24 | 45 | GO:0030479; C:actin cortical patch; TAS:PomBase.::GO:0051285; C:cell cortex of cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IC:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase. | | | | | | | | | | GO:0051666; P:actin cortical patch localization; IMP:PomBase.::GO:0030037; P:actin filament reorganization involved in cell cycle; IMP:PomBase.::GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0033554; P:cellular response to stress; IGI:PomBase.::GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IMP:PomBase.::GO:0010590; P:regulation of cytokinetic cell separation; IMP:PomBase.::GO:2000100; P:regulation of establishment or maintenance of bipolar cell polarity regulating cell shape; IMP:PomBase. | 291 | P08069 | 1367 | IGF1R_HUMAN Insulin-like growth factor 1 rece... | 240 | 0.001 | 47.4 | 25 | 43 | GO:0005887; C:integral to plasma membrane; IC:UniProtKB.::GO:0005792; C:microsome; IDA:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0043559; F:insulin binding; IPI:BHF-UCL.::GO:0005158; F:insulin receptor binding; IDA:BHF-UCL.::GO:0043560; F:insulin receptor substrate binding; IPI:UniProtKB.::GO:0031994; F:insulin-like growth factor I binding; IPI:BHF-UCL.::GO:0005010; F:insulin-like growth factor-activated receptor activity; IDA:UniProtKB.::GO:0043548; F:phosphatidylinositol 3-kinase binding; IPI:UniProtKB. | | | | | | | | | | GO:0006916; P:anti-apoptosis; TAS:ProtInc.::GO:0006955; P:immune response; IMP:BHF-UCL.::GO:0051389; P:inactivation of MAPKK activity; IDA:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:ProtInc.::GO:0014065; P:phosphatidylinositol 3-kinase cascade; IC:BHF-UCL.::GO:0030335; P:positive regulation of cell migration; IMP:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.::GO:0045740; P:positive regulation of DNA replication; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0051262; P:protein tetramerization; IDA:UniProtKB.::GO:0046328; P:regulation of JNK cascade; IDA:UniProtKB. | 292 | Q7TQP6 | 835 | TNI3K_RAT Serine/threonine-protein kinase TNN... | 233 | 0.001 | 47 | 22 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 293 | Q60806 | 631 | PLK3_MOUSE Serine/threonine-protein kinase PL... | 188 | 0.001 | 47 | 25 | 40 | GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005795; C:Golgi stack; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0002039; F:p53 binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071779; P:G1/S transition checkpoint; IMP:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0090166; P:Golgi disassembly; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:2000777; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; IMP:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IMP:UniProtKB.::GO:0006970; P:response to osmotic stress; ISS:UniProtKB.::GO:0009314; P:response to radiation; ISS:UniProtKB.::GO:0000302; P:response to reactive oxygen species; ISS:UniProtKB.::GO:0000084; P:S phase of mitotic cell cycle; ISS:UniProtKB. | 294 | Q62799 | 1339 | ERBB3_RAT Receptor tyrosine-protein kinase er... | 166 | 0.001 | 47 | 23 | 42 | GO:0016021; C:integral to membrane; TAS:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0045211; C:postsynaptic membrane; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004716; F:receptor signaling protein tyrosine kinase activity; IEA:InterPro.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; TAS:RGD. | | | | | | | | | | GO:0007409; P:axonogenesis; IEP:RGD.::GO:0032869; P:cellular response to insulin stimulus; IEP:RGD.::GO:0007623; P:circadian rhythm; IEP:RGD.::GO:0060056; P:mammary gland involution; IEP:RGD.::GO:0042476; P:odontogenesis; IEP:RGD.::GO:0046326; P:positive regulation of glucose import; IMP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0009611; P:response to wounding; IEP:RGD.::GO:0007519; P:skeletal muscle tissue development; IEP:RGD.::GO:0043586; P:tongue development; IEP:RGD.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:RGD. | 295 | C0LGV0 | 895 | Y5487_ARATH Probable LRR receptor-like serine... | 173 | 0.001 | 47 | 24 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 296 | Q7Z2Y5 | 1582 | NRK_HUMAN Nik-related protein kinase OS=Homo ... | 224 | 0.001 | 47.4 | 21 | 40 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | | 297 | Q61526 | 1339 | ERBB3_MOUSE Receptor tyrosine-protein kinase ... | 166 | 0.001 | 47 | 23 | 42 | GO:0016324; C:apical plasma membrane; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0016328; C:lateral plasma membrane; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004716; F:receptor signaling protein tyrosine kinase activity; IEA:InterPro.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0021545; P:cranial nerve development; IMP:MGI.::GO:0003197; P:endocardial cushion development; IMP:MGI.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:MGI.::GO:0014037; P:Schwann cell differentiation; IMP:MGI.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro. | 298 | Q23356 | 1096 | MIG15_CAEEL Serine/threonine-protein kinase m... | 199 | 0.001 | 47 | 24 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0010171; P:body morphogenesis; IGI:WormBase.::GO:0033563; P:dorsal/ventral axon guidance; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040039; P:inductive cell migration; IMP:WormBase.::GO:0019915; P:lipid storage; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase. | 299 | Q9M0G7 | 1013 | PXL2_ARATH Leucine-rich repeat receptor-like ... | 250 | 0.001 | 47 | 23 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0010067; P:procambium histogenesis; ISS:UniProtKB. | 300 | Q9JI10 | 497 | STK3_MOUSE Serine/threonine-protein kinase 3 ... | 244 | 0.001 | 46.6 | 24 | 40 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0046983; F:protein dimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0060706; P:cell differentiation involved in embryonic placenta development; IGI:MGI.::GO:0007417; P:central nervous system development; IGI:MGI.::GO:0003157; P:endocardium development; IGI:MGI.::GO:0035329; P:hippo signaling cascade; IMP:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IGI:MGI.::GO:0008285; P:negative regulation of cell proliferation; IGI:MGI.::GO:0046621; P:negative regulation of organ growth; IGI:MGI.::GO:0001841; P:neural tube formation; IGI:MGI.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0060215; P:primitive hemopoiesis; IGI:MGI. | 301 | Q8R4K2 | 459 | IRAK4_MOUSE Interleukin-1 receptor-associated... | 189 | 0.001 | 46.6 | 26 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005149; F:interleukin-1 receptor binding; IPI:MGI.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0001816; P:cytokine production; IDA:MGI.::GO:0019221; P:cytokine-mediated signaling pathway; IDA:MGI.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW. |
