| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
331 | P53406 | 359 | ISL2A_DANRE Insulin gene enhancer protein isl... | 124 | 0.002 | 45.8 | 25 | 38 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0048676; P:axon extension involved in development; IMP:ZFIN.::GO:0048665; P:neuron fate specification; IMP:ZFIN. | 332 | Q9Z0S2 | 406 | LHX2_MOUSE LIM/homeobox protein Lhx2 OS=Mus m... | 130 | 0.002 | 45.8 | 22 | 38 | GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0000988; F:protein binding transcription factor activity; IPI:MGI.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007411; P:axon guidance; IMP:MGI.::GO:0009953; P:dorsal/ventral pattern formation; IMP:MGI.::GO:0007498; P:mesoderm development; IMP:MGI.::GO:2000678; P:negative regulation of transcription regulatory region DNA binding; IGI:MGI.::GO:0001843; P:neural tube closure; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0021978; P:telencephalon regionalization; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 333 | P50458 | 406 | LHX2_HUMAN LIM/homeobox protein Lhx2 OS=Homo ... | 107 | 0.002 | 45.8 | 23 | 39 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 334 | P23727 | 724 | P85A_BOVIN Phosphatidylinositol 3-kinase regu... | 148 | 0.002 | 46.2 | 21 | 49 | GO:0005943; C:1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; ISS:UniProtKB. | | | | | | | | | | GO:0043125; F:ErbB-3 class receptor binding; ISS:UniProtKB.::GO:0005158; F:insulin receptor binding; ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; ISS:UniProtKB.::GO:0005159; F:insulin-like growth factor receptor binding; ISS:UniProtKB.::GO:0035014; F:phosphatidylinositol 3-kinase regulator activity; ISS:UniProtKB. | | | | | | | | | | GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0046854; P:phosphatidylinositol phosphorylation; ISS:UniProtKB.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; IMP:BHF-UCL.::GO:0046326; P:positive regulation of glucose import; IMP:BHF-UCL. | 335 | Q3SX26 | 481 | TRIP6_BOVIN Thyroid receptor-interacting prot... | 113 | 0.002 | 45.8 | 27 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005149; F:interleukin-1 receptor binding; ISS:UniProtKB.::GO:0019900; F:kinase binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008588; P:release of cytoplasmic sequestered NF-kappaB; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 336 | D2H9U0 | 547 | RHG36_AILME Rho GTPase-activating protein 36 ... | 194 | 0.002 | 45.8 | 25 | 45 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 337 | P17121 | 654 | SAC7_YEAST GTPase-activating protein SAC7 OS=... | 75 | 0.092 | 40.4 | 29 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; TAS:SGD. | | | | | | | | | | GO:0030037; P:actin filament reorganization involved in cell cycle; IMP:SGD.::GO:0007264; P:small GTPase mediated signal transduction; TAS:SGD. | 338 | Q9P3B1 | 374 | YIL2_SCHPO Putative Rho GTPase-activating pro... | 146 | 0.002 | 45.4 | 23 | 49 | GO:0005794; C:Golgi apparatus; IDA:PomBase. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 339 | Q16527 | 193 | CSRP2_HUMAN Cysteine and glycine-rich protein... | 53 | 4.9 | 33.9 | 28 | 51 | GO:0005634; C:nucleus; NAS:UniProtKB. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 340 | Q32LE9 | 193 | CSRP2_BOVIN Cysteine and glycine-rich protein... | 53 | 4.9 | 33.9 | 28 | 51 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 341 | Q62908 | 193 | CSRP2_RAT Cysteine and glycine-rich protein 2... | 53 | 7 | 33.5 | 28 | 49 | GO:0005634; C:nucleus; IDA:RGD. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045445; P:myoblast differentiation; IEP:RGD. | 342 | P50464 | 348 | UNC97_CAEEL LIM domain-containing protein unc... | 162 | 0.036 | 41.6 | 21 | 35 | GO:0005912; C:adherens junction; IDA:WormBase.::GO:0031430; C:M band; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.::GO:0055120; C:striated muscle dense body; IDA:WormBase. | | | | | | | | | | GO:0017022; F:myosin binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045216; P:cell-cell junction organization; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0019915; P:lipid storage; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0007517; P:muscle organ development; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0050954; P:sensory perception of mechanical stimulus; IMP:WormBase.::GO:0061199; P:striated muscle contraction involved in embryonic body morphogenesis; IMP:WormBase. | 343 | P67967 | 192 | CSRP1_COTJA Cysteine and glycine-rich protein... | 54 | 0.003 | 43.9 | 37 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 344 | P67966 | 192 | CSRP1_CHICK Cysteine and glycine-rich protein... | 54 | 0.003 | 43.9 | 37 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 345 | Q96A47 | 359 | ISL2_HUMAN Insulin gene enhancer protein ISL-... | 99 | 0.003 | 45.1 | 26 | 38 | GO:0005634; C:nucleus; IC:BHF-UCL. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0048935; P:peripheral nervous system neuron development; TAS:BHF-UCL. | 346 | Q15654 | 476 | TRIP6_HUMAN Thyroid receptor-interacting prot... | 125 | 0.003 | 45.1 | 25 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005149; F:interleukin-1 receptor binding; IDA:UniProtKB.::GO:0019900; F:kinase binding; IPI:UniProtKB.::GO:0046966; F:thyroid hormone receptor binding; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0048041; P:focal adhesion assembly; NAS:UniProtKB.::GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008588; P:release of cytoplasmic sequestered NF-kappaB; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 347 | Q63787 | 724 | P85A_RAT Phosphatidylinositol 3-kinase regula... | 172 | 0.003 | 45.4 | 20 | 49 | GO:0005943; C:1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0019717; C:synaptosome; IDA:RGD. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; TAS:RGD.::GO:0046935; F:1-phosphatidylinositol-3-kinase regulator activity; IDA:RGD.::GO:0051117; F:ATPase binding; IPI:RGD.::GO:0005516; F:calmodulin binding; IPI:RGD.::GO:0043125; F:ErbB-3 class receptor binding; ISS:UniProtKB.::GO:0030331; F:estrogen receptor binding; IPI:RGD.::GO:0005158; F:insulin receptor binding; ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; ISS:UniProtKB.::GO:0005159; F:insulin-like growth factor receptor binding; ISS:UniProtKB.::GO:0043548; F:phosphatidylinositol 3-kinase binding; IPI:RGD.::GO:0051219; F:phosphoprotein binding; IPI:RGD.::GO:0008022; F:protein C-terminus binding; IDA:RGD.::GO:0019904; F:protein domain specific binding; IPI:RGD.::GO:0019901; F:protein kinase binding; IPI:RGD.::GO:0030971; F:receptor tyrosine kinase binding; IPI:RGD.::GO:0031625; F:ubiquitin protein ligase binding; IPI:RGD. | | | | | | | | | | GO:0071398; P:cellular response to fatty acid; IEP:RGD.::GO:0006006; P:glucose metabolic process; IMP:RGD.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0045776; P:negative regulation of blood pressure; IMP:RGD.::GO:0022408; P:negative regulation of cell-cell adhesion; IMP:RGD.::GO:0010459; P:negative regulation of heart rate; IMP:RGD.::GO:0045861; P:negative regulation of proteolysis; IMP:RGD.::GO:0048662; P:negative regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0045768; P:positive regulation of anti-apoptosis; IMP:RGD.::GO:0030335; P:positive regulation of cell migration; IMP:RGD.::GO:0045663; P:positive regulation of myoblast differentiation; IMP:RGD.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:RGD.::GO:0043200; P:response to amino acid stimulus; IEP:RGD.::GO:0051591; P:response to cAMP; IDA:RGD.::GO:0071548; P:response to dexamethasone stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0009750; P:response to fructose stimulus; IEP:RGD.::GO:0070848; P:response to growth factor stimulus; IEP:RGD.::GO:0010040; P:response to iron(II) ion; IEP:RGD.::GO:0007584; P:response to nutrient; IEP:RGD.::GO:0032570; P:response to progesterone stimulus; IEP:RGD.::GO:0033574; P:response to testosterone stimulus; IEP:RGD.::GO:0001878; P:response to yeast; IEP:RGD. | 348 | Q1JQB5 | 378 | FBLI1_BOVIN Filamin-binding LIM protein 1 OS=... | 99 | 0.003 | 45.1 | 29 | 42 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0001725; C:stress fiber; ISS:UniProtKB. | | | | | | | | | | GO:0031005; F:filamin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016337; P:cell-cell adhesion; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0033623; P:regulation of integrin activation; ISS:UniProtKB. | 349 | P97314 | 193 | CSRP2_MOUSE Cysteine and glycine-rich protein... | 53 | 5.2 | 33.9 | 28 | 51 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 350 | Q5M8V8 | 158 | RBTN2_XENTR Rhombotin-2 OS=Xenopus tropicalis... | 134 | 0.003 | 42.7 | 22 | 37 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB. | 351 | Q9CXV0 | 359 | ISL2_MOUSE Insulin gene enhancer protein ISL-... | 99 | 0.004 | 44.7 | 26 | 38 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045665; P:negative regulation of neuron differentiation; IMP:MGI.::GO:0031290; P:retinal ganglion cell axon guidance; IMP:MGI.::GO:0021520; P:spinal cord motor neuron cell fate specification; IGI:MGI.::GO:0021524; P:visceral motor neuron differentiation; IMP:MGI. | 352 | B7ZUL2 | 593 | LIMD1_XENTR LIM domain-containing protein 1 O... | 126 | 0.82 | 37.4 | 24 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0014032; P:neural crest cell development; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 353 | Q71FD7 | 375 | FBLI1_MOUSE Filamin-binding LIM protein 1 OS=... | 100 | 0.004 | 44.7 | 29 | 42 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0001725; C:stress fiber; ISS:UniProtKB. | | | | | | | | | | GO:0031005; F:filamin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016337; P:cell-cell adhesion; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0033623; P:regulation of integrin activation; ISS:UniProtKB. | 354 | P36198 | 426 | LHX2_RAT LIM/homeobox protein Lhx2 OS=Rattus ... | 107 | 0.004 | 44.7 | 23 | 39 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 355 | Q0VA45 | 674 | ZYX_XENTR Zyxin OS=Xenopus tropicalis (Wester... | 58 | 1.9 | 36.2 | 21 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0001725; C:stress fiber; ISS:UniProtKB. | | | | | | | | | | GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 356 | Q54VW7 | 1203 | GACGG_DICDI Rho GTPase-activating protein gac... | 160 | 0.004 | 45.1 | 26 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 357 | Q54GD0 | 920 | MGP1_DICDI Mental retardation GTPase activati... | 149 | 0.005 | 45.1 | 18 | 47 | GO:0000331; C:contractile vacuole; IDA:dictyBase.::GO:0005829; C:cytosol; IDA:dictyBase. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0033298; P:contractile vacuole organization; IMP:dictyBase.::GO:0006887; P:exocytosis; IGI:dictyBase.::GO:0051490; P:negative regulation of filopodium assembly; IMP:dictyBase.::GO:0042331; P:phototaxis; IGI:dictyBase.::GO:0051270; P:regulation of cellular component movement; IMP:dictyBase.::GO:0007165; P:signal transduction; IEA:InterPro. | 358 | Q9Z1Z9 | 457 | PDLI7_RAT PDZ and LIM domain protein 7 OS=Rat... | 152 | 0.15 | 39.7 | 24 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0001503; P:ossification; IEA:UniProtKB-KW.::GO:0045669; P:positive regulation of osteoblast differentiation; IDA:RGD. | 359 | Q06BR1 | 612 | LIMD1_XENLA LIM domain-containing protein 1 O... | 126 | 6 | 34.7 | 23 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0014032; P:neural crest cell development; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 360 | P50460 | 194 | CSRP2_CHICK Cysteine and glycine-rich protein... | 53 | 8.8 | 33.1 | 26 | 45 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 361 | P50480 | 360 | ISL2_RAT Insulin gene enhancer protein ISL-2 ... | 99 | 0.005 | 44.3 | 26 | 38 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. |
