rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
211 | Q55GP8 | 684 | GACO_DICDI Rho GTPase-activating protein gacO... | 158 | 0.0000003 | 58.5 | 27 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 212 | P53671 | 638 | LIMK2_HUMAN LIM domain kinase 2 OS=Homo sapie... | 131 | 0.0000003 | 58.5 | 28 | 44 | GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; TAS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0042325; P:regulation of phosphorylation; IEA:InterPro. | 213 | A7MB27 | 530 | RHG36_BOVIN Rho GTPase-activating protein 36 ... | 157 | 0.0000003 | 58.2 | 27 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 214 | Q54Y72 | 338 | GACA_DICDI Rho GTPase-activating protein gacA... | 194 | 0.0000004 | 57 | 30 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 215 | P59281 | 1107 | RHG39_MOUSE Rho GTPase-activating protein 39 ... | 173 | 0.0000006 | 57.8 | 30 | 46 | GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 216 | Q54C77 | 1186 | Y3184_DICDI Probable inactive serine/threonin... | 148 | 0.0000007 | 57.4 | 25 | 50 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 217 | Q32L23 | 638 | LIMK2_BOVIN LIM domain kinase 2 OS=Bos taurus... | 127 | 0.000001 | 56.6 | 27 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 218 | Q8BRH3 | 494 | RHG19_MOUSE Rho GTPase-activating protein 19 ... | 220 | 0.000001 | 56.6 | 23 | 48 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 219 | Q14CB8 | 494 | RHG19_HUMAN Rho GTPase-activating protein 19 ... | 220 | 0.000001 | 56.2 | 23 | 48 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 220 | Q8BL65 | 612 | ABLM2_MOUSE Actin-binding LIM protein 2 OS=Mu... | 94 | 2.7 | 35.8 | 24 | 37 | GO:0030016; C:myofibril; IDA:MGI. | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; IEA:InterPro.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI. | 221 | Q292U5 | 795 | ESN_DROPS Protein espinas OS=Drosophila pseud... | 246 | 0.000002 | 55.8 | 24 | 37 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 222 | Q2YDK0 | 284 | FHL5_BOVIN Four and a half LIM domains protei... | 117 | 0.068 | 40.4 | 24 | 37 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 223 | Q9VY77 | 728 | AJUBA_DROME LIM domain-containing protein jub... | 125 | 0.000002 | 55.8 | 26 | 47 | GO:0005912; C:adherens junction; IDA:FlyBase. | | | | | | | | | | GO:0003779; F:actin binding; ISS:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035329; P:hippo signaling cascade; IMP:FlyBase.::GO:0045572; P:positive regulation of imaginal disc growth; IMP:FlyBase. | 224 | Q553X3 | 799 | GACI_DICDI Rho GTPase-activating protein gacI... | 82 | 0.000002 | 55.8 | 32 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 225 | Q6ZRI8 | 547 | RHG36_HUMAN Rho GTPase-activating protein 36 ... | 157 | 0.000003 | 55.1 | 26 | 46 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 226 | Q6KC51 | 612 | ABLM2_RAT Actin-binding LIM protein 2 OS=Ratt... | 94 | 2.9 | 35.8 | 24 | 37 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; IEA:InterPro. | 227 | Q5R685 | 724 | P85A_PONAB Phosphatidylinositol 3-kinase regu... | 168 | 0.000003 | 55.1 | 21 | 50 | GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro. | | | | | | | | | | GO:0035014; F:phosphatidylinositol 3-kinase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 228 | Q54NL0 | 1009 | GACT_DICDI Rho GTPase-activating protein gacT... | 150 | 0.000003 | 55.1 | 25 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro.::GO:0030587; P:sorocarp development; IMP:dictyBase. | 229 | Q6H8Q1 | 611 | ABLM2_HUMAN Actin-binding LIM protein 2 OS=Ho... | 94 | 2.3 | 36.2 | 24 | 37 | GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0005737; C:cytoplasm; IDA:HPA.::GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007010; P:cytoskeleton organization; IEA:InterPro. | 230 | P26450 | 724 | P85A_MOUSE Phosphatidylinositol 3-kinase regu... | 170 | 0.000004 | 54.7 | 24 | 47 | GO:0005943; C:1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; ISS:UniProtKB. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; TAS:MGI.::GO:0043125; F:ErbB-3 class receptor binding; ISS:UniProtKB.::GO:0005158; F:insulin receptor binding; ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; IPI:UniProtKB.::GO:0005159; F:insulin-like growth factor receptor binding; ISS:UniProtKB. | | | | | | | | | | GO:0030183; P:B cell differentiation; IMP:MGI.::GO:0034644; P:cellular response to UV; IMP:MGI.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IDA:MGI.::GO:0001953; P:negative regulation of cell-matrix adhesion; IGI:MGI.::GO:0045671; P:negative regulation of osteoclast differentiation; IGI:MGI.::GO:0051531; P:NFAT protein import into nucleus; IMP:MGI.::GO:0043065; P:positive regulation of apoptotic process; IMP:MGI.::GO:0030335; P:positive regulation of cell migration; IGI:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0006468; P:protein phosphorylation; IDA:MGI. | 231 | Q8IR79 | 1257 | LIMK1_DROME LIM domain kinase 1 OS=Drosophila... | 163 | 0.000005 | 54.7 | 31 | 42 | GO:0005826; C:actomyosin contractile ring; IDA:UniProtKB.::GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.::GO:0048749; P:compound eye development; IGI:FlyBase.::GO:0001737; P:establishment of imaginal disc-derived wing hair orientation; IMP:FlyBase.::GO:0050770; P:regulation of axonogenesis; IMP:FlyBase.::GO:0051124; P:synaptic growth at neuromuscular junction; IMP:FlyBase. | 232 | Q99JW4 | 325 | LIMS1_MOUSE LIM and senescent cell antigen-li... | 126 | 0.96 | 37 | 22 | 33 | GO:0005925; C:focal adhesion; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016337; P:cell-cell adhesion; IMP:MGI.::GO:0007160; P:cell-matrix adhesion; IMP:MGI.::GO:0043009; P:chordate embryonic development; IMP:MGI.::GO:0007163; P:establishment or maintenance of cell polarity; IMP:MGI. | 233 | P48059 | 325 | LIMS1_HUMAN LIM and senescent cell antigen-li... | 126 | 1.5 | 36.2 | 22 | 32 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0007569; P:cell aging; TAS:ProtInc.::GO:0034329; P:cell junction assembly; TAS:Reactome.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB. | 234 | O35115 | 279 | FHL2_RAT Four and a half LIM domains protein ... | 123 | 0.002 | 45.1 | 25 | 40 | GO:0031430; C:M band; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IDA:RGD. | | | | | | | | | | GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 235 | O42565 | 615 | LIMK1_XENLA LIM domain kinase 1 OS=Xenopus la... | 60 | 2.1 | 36.2 | 27 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 236 | B2RWW0 | 714 | TAGAP_MOUSE T-cell activation Rho GTPase-acti... | 172 | 0.000006 | 54.3 | 27 | 48 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 237 | Q2KJ33 | 341 | LIMS2_BOVIN LIM and senescent cell antigen-li... | 126 | 1.9 | 35.8 | 21 | 33 | GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 238 | Q69ZX8 | 682 | ABLM3_MOUSE Actin-binding LIM protein 3 OS=Mu... | 157 | 0.011 | 43.5 | 22 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; IEA:InterPro.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI. | 239 | Q6AXT1 | 284 | FHL5_RAT Four and a half LIM domains protein ... | 117 | 0.12 | 39.7 | 24 | 36 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 240 | Q9WTX7 | 284 | FHL5_MOUSE Four and a half LIM domains protei... | 117 | 0.17 | 39.3 | 24 | 36 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003713; F:transcription coactivator activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; TAS:MGI. | 241 | Q28FG2 | 833 | PRIC1_XENTR Prickle-like protein 1 OS=Xenopus... | 126 | 0.04 | 42 | 29 | 38 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009948; P:anterior/posterior axis specification; ISS:UniProtKB.::GO:0060027; P:convergent extension involved in gastrulation; ISS:UniProtKB.::GO:0001736; P:establishment of planar polarity; ISS:UniProtKB. |