rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
181 | P53666 | 642 | LIMK2_CHICK LIM domain kinase 2 OS=Gallus gal... | 127 | 0.0000000004 | 67.8 | 28 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 182 | Q3E875 | 376 | RGAP1_ARATH Uncharacterized Rho GTPase-activa... | 147 | 0.0000000005 | 66.2 | 27 | 50 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 183 | Q96P48 | 1450 | ARAP1_HUMAN Arf-GAP with Rho-GAP domain, ANK ... | 179 | 0.0000000006 | 67.8 | 30 | 49 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IDA:UniProtKB.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005100; F:Rho GTPase activator activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030037; P:actin filament reorganization involved in cell cycle; TAS:UniProtKB.::GO:0051497; P:negative regulation of stress fiber assembly; IMP:UniProtKB.::GO:0043089; P:positive regulation of Cdc42 GTPase activity; IDA:UniProtKB.::GO:0051491; P:positive regulation of filopodium assembly; IMP:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:0051270; P:regulation of cellular component movement; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 184 | P40809 | 384 | RG84C_DROME GTPase-activating protein RacGAP8... | 183 | 0.0000000008 | 65.9 | 27 | 45 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IDA:FlyBase.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0001745; P:compound eye morphogenesis; IMP:FlyBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0007283; P:spermatogenesis; IMP:FlyBase. | 185 | Q54QF4 | 909 | MGP4_DICDI Mental retardation GTPase activati... | 158 | 0.0000000009 | 67 | 27 | 51 | GO:0000331; C:contractile vacuole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 186 | O74335 | 361 | RGA5_SCHPO Rho-GTPase-activating protein 5 OS... | 176 | 0.0000000009 | 65.5 | 28 | 48 | GO:0051286; C:cell tip; IDA:PomBase.::GO:0031097; C:medial cortex; IDA:PomBase.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; IDA:PomBase. | | | | | | | | | | GO:0008360; P:regulation of cell shape; IMP:PomBase.::GO:0090334; P:regulation of cell wall (1->3)-beta-D-glucan biosynthetic process; IMP:PomBase.::GO:0007165; P:signal transduction; IEA:InterPro. | 187 | Q4LDD4 | 1452 | ARAP1_MOUSE Arf-GAP with Rho-GAP domain, ANK ... | 179 | 0.000000001 | 66.6 | 30 | 49 | GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070412; F:R-SMAD binding; ISS:BHF-UCL.::GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:BHF-UCL.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007184; P:SMAD protein import into nucleus; ISS:UniProtKB.::GO:0060395; P:SMAD protein signal transduction; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB. | 188 | P97447 | 280 | FHL1_MOUSE Four and a half LIM domains protei... | 122 | 0.005 | 43.9 | 22 | 36 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 189 | E9Q6X9 | 672 | RHG40_MOUSE Rho GTPase-activating protein 40 ... | 171 | 0.000000002 | 65.1 | 30 | 50 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 190 | Q8BZ05 | 1703 | ARAP2_MOUSE Arf-GAP with Rho-GAP domain, ANK ... | 192 | 0.000000003 | 65.5 | 28 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 191 | Q8K2H3 | 851 | FA13B_MOUSE Protein FAM13B OS=Mus musculus (M... | 158 | 0.000000003 | 65.1 | 26 | 51 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 192 | Q8WZ64 | 1704 | ARAP2_HUMAN Arf-GAP with Rho-GAP domain, ANK ... | 147 | 0.000000004 | 65.1 | 29 | 47 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 193 | Q8K0Q5 | 663 | RHG18_MOUSE Rho GTPase-activating protein 18 ... | 151 | 0.000000004 | 64.7 | 28 | 48 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 194 | Q8BN58 | 729 | RHG28_MOUSE Rho GTPase-activating protein 28 ... | 196 | 0.000000004 | 64.7 | 27 | 46 | | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 195 | Q9WUH4 | 280 | FHL1_RAT Four and a half LIM domains protein ... | 122 | 0.005 | 43.9 | 22 | 36 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 196 | Q54FF4 | 734 | GACL_DICDI Rho GTPase-activating protein gacL... | 208 | 0.000000004 | 64.3 | 26 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 197 | P35688 | 1017 | LRG1_YEAST Rho-GTPase-activating protein LRG1... | 44 | 0.015 | 43.1 | 34 | 64 | GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009272; P:fungal-type cell wall biogenesis; IGI:SGD.::GO:0007264; P:small GTPase mediated signal transduction; IPI:SGD.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW. | 198 | Q9NYF5 | 915 | FA13B_HUMAN Protein FAM13B OS=Homo sapiens (H... | 178 | 0.000000006 | 64.3 | 25 | 51 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 199 | Q8K4G5 | 861 | ABLM1_MOUSE Actin-binding LIM protein 1 OS=Mu... | 97 | 0.0002 | 49.3 | 27 | 39 | GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007411; P:axon guidance; IDA:MGI.::GO:0007010; P:cytoskeleton organization; IEA:InterPro.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI. | 200 | Q54XT6 | 783 | GACR_DICDI Rho GTPase-activating protein gacR... | 169 | 0.00000002 | 62.8 | 25 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 201 | Q13642 | 323 | FHL1_HUMAN Four and a half LIM domains protei... | 115 | 0.0000005 | 56.6 | 30 | 43 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; NAS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.::GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; IDA:UniProtKB.::GO:0010972; P:negative regulation of G2/M transition of mitotic cell cycle; IDA:UniProtKB.::GO:0009887; P:organ morphogenesis; NAS:UniProtKB. | 202 | B1AUC7 | 590 | RHG36_MOUSE Rho GTPase-activating protein 36 ... | 194 | 0.00000003 | 61.6 | 26 | 46 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 203 | Q9VDG2 | 625 | RLIP_DROME RalA-binding protein 1 OS=Drosophi... | 150 | 0.00000003 | 61.6 | 27 | 50 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017160; F:Ral GTPase binding; IPI:FlyBase. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006898; P:receptor-mediated endocytosis; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 204 | Q8UUU2 | 722 | P85AA_XENLA Phosphatidylinositol 3-kinase reg... | 151 | 0.00000003 | 61.6 | 26 | 53 | GO:0005943; C:1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; ISS:UniProtKB. | | | | | | | | | | GO:0043125; F:ErbB-3 class receptor binding; ISS:UniProtKB.::GO:0005158; F:insulin receptor binding; ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; ISS:UniProtKB.::GO:0005159; F:insulin-like growth factor receptor binding; ISS:UniProtKB.::GO:0035014; F:phosphatidylinositol 3-kinase regulator activity; ISS:UniProtKB. | | | | | | | | | | GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0046854; P:phosphatidylinositol phosphorylation; ISS:UniProtKB. | 205 | Q8QFP8 | 662 | LIMK1_CHICK LIM domain kinase 1 OS=Gallus gal... | 138 | 0.00000003 | 61.6 | 27 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030426; C:growth cone; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 206 | O54785 | 638 | LIMK2_MOUSE LIM domain kinase 2 OS=Mus muscul... | 129 | 0.00000008 | 60.1 | 27 | 46 | GO:0005801; C:cis-Golgi network; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007283; P:spermatogenesis; IMP:MGI. | 207 | O14639 | 778 | ABLM1_HUMAN Actin-binding LIM protein 1 OS=Ho... | 115 | 0.0005 | 48.1 | 25 | 38 | GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007010; P:cytoskeleton organization; IEA:InterPro.::GO:0009887; P:organ morphogenesis; TAS:ProtInc.::GO:0007601; P:visual perception; TAS:ProtInc. | 208 | P53670 | 638 | LIMK2_RAT LIM domain kinase 2 OS=Rattus norve... | 131 | 0.0000002 | 58.9 | 26 | 46 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007286; P:spermatid development; TAS:RGD. | 209 | Q5F3G0 | 495 | RHG19_CHICK Rho GTPase-activating protein 19 ... | 220 | 0.0000002 | 58.5 | 24 | 49 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 210 | Q9C0H5 | 1083 | RHG39_HUMAN Rho GTPase-activating protein 39 ... | 173 | 0.0000002 | 58.9 | 30 | 46 | GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 211 | Q55GP8 | 684 | GACO_DICDI Rho GTPase-activating protein gacO... | 158 | 0.0000003 | 58.5 | 27 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. |