rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
571 | Q12933 | 501 | TRAF2_HUMAN TNF receptor-associated factor 2 ... | 50 | 6.5 | 32.7 | 32 | 44 | GO:0035631; C:CD40 receptor complex; ISS:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0009898; C:internal side of plasma membrane; ISS:BHF-UCL. | | | | | | | | | | GO:0005174; F:CD40 receptor binding; ISS:BHF-UCL.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004871; F:signal transducer activity; NAS:ProtInc.::GO:0046625; F:sphingolipid binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; TAS:Reactome.::GO:0007250; P:activation of NF-kappaB-inducing kinase activity; IMP:UniProtKB.::GO:0008633; P:activation of pro-apoptotic gene products; TAS:Reactome.::GO:0043623; P:cellular protein complex assembly; ISS:BHF-UCL.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.::GO:0032743; P:positive regulation of interleukin-2 production; IMP:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; IDA:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:BHF-UCL.::GO:0050870; P:positive regulation of T cell activation; IC:UniProtKB.::GO:0002726; P:positive regulation of T cell cytokine production; IMP:UniProtKB.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0070207; P:protein homotrimerization; IPI:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IDA:UniProtKB. | 572 | Q9UKV5 | 643 | AMFR2_HUMAN E3 ubiquitin-protein ligase AMFR ... | 41 | 6.8 | 32.7 | 34 | 46 | GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0000299; C:integral to membrane of membrane fraction; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030968; P:endoplasmic reticulum unfolded protein response; IMP:UniProtKB.::GO:0030433; P:ER-associated protein catabolic process; IDA:UniProtKB.::GO:0051259; P:protein oligomerization; IDA:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB. | 573 | Q96A61 | 297 | TRI52_HUMAN Tripartite motif-containing prote... | 30 | 7 | 32.3 | 37 | 53 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 574 | Q9R049 | 643 | AMFR_MOUSE E3 ubiquitin-protein ligase AMFR O... | 41 | 7.5 | 32.7 | 34 | 46 | GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030433; P:ER-associated protein catabolic process; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB. | 575 | Q54EF7 | 100 | Y5454_DICDI Uncharacterized protein DDB_G0291... | 41 | 7.5 | 30.8 | 32 | 41 | | | | | | | | | | | | | | | | | | | | | | 576 | Q56R14 | 1091 | TRI33_XENLA E3 ubiquitin-protein ligase TRIM3... | 78 | 7.5 | 32.7 | 29 | 45 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 577 | Q9LUZ9 | 308 | ATL63_ARATH RING-H2 finger protein ATL63 OS=A... | 81 | 7.7 | 32.3 | 30 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 578 | Q9SL78 | 390 | ATL12_ARATH Putative RING-H2 finger protein A... | 55 | 7.7 | 32.7 | 31 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 579 | Q8IYW5 | 571 | RN168_HUMAN E3 ubiquitin-protein ligase RNF16... | 41 | 7.9 | 32.7 | 29 | 51 | GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; IDA:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0043130; F:ubiquitin binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006302; P:double-strand break repair; IDA:UniProtKB.::GO:0070535; P:histone H2A K63-linked ubiquitination; IDA:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; IDA:UniProtKB.::GO:0010212; P:response to ionizing radiation; IDA:UniProtKB. | 580 | A6NGJ6 | 449 | TRI64_HUMAN Tripartite motif-containing prote... | 68 | 8 | 32.7 | 25 | 44 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 581 | Q80VI1 | 734 | TRI56_MOUSE E3 ubiquitin-protein ligase TRIM5... | 41 | 8.3 | 32.7 | 34 | 56 | GO:0005737; C:cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051607; P:defense response to virus; IMP:UniProtKB.::GO:0032608; P:interferon-beta production; IMP:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0034340; P:response to type I interferon; IDA:UniProtKB. | 582 | Q99MP8 | 591 | BRAP_MOUSE BRCA1-associated protein OS=Mus mu... | 68 | 8.7 | 32.7 | 32 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 583 | Q681I0 | 465 | ORTHL_ARATH E3 ubiquitin-protein ligase ORTHR... | 58 | 8.7 | 32.3 | 24 | 41 | GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0008327; F:methyl-CpG binding; ISS:UniProtKB.::GO:0010428; F:methyl-CpNpG binding; ISS:UniProtKB.::GO:0010429; F:methyl-CpNpN binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0010424; P:DNA methylation on cytosine within a CG sequence; ISS:UniProtKB. | 584 | B0BLU1 | 535 | RN168_XENTR E3 ubiquitin-protein ligase RNF16... | 40 | 9 | 32.3 | 30 | 53 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0070535; P:histone H2A K63-linked ubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB. | 585 | Q6GND7 | 203 | R152A_XENLA E3 ubiquitin-protein ligase rnf15... | 53 | 9.2 | 32 | 28 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB. | 586 | Q3UV31 | 285 | RN223_MOUSE RING finger protein 223 OS=Mus mu... | 62 | 9.6 | 32 | 29 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 587 | Q13049 | 653 | TRI32_HUMAN E3 ubiquitin-protein ligase TRIM3... | 89 | 9.9 | 32.3 | 22 | 44 | GO:0005634; C:nucleus; ISS:BHF-UCL. | | | | | | | | | | GO:0017022; F:myosin binding; ISS:BHF-UCL.::GO:0043621; F:protein self-association; IDA:UniProtKB.::GO:0003723; F:RNA binding; ISS:BHF-UCL.::GO:0030957; F:Tat protein binding; TAS:BHF-UCL.::GO:0003713; F:transcription coactivator activity; TAS:ProtInc.::GO:0031369; F:translation initiation factor binding; ISS:BHF-UCL.::GO:0043130; F:ubiquitin binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045444; P:fat cell differentiation; ISS:BHF-UCL.::GO:0045087; P:innate immune response; TAS:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; IDA:BHF-UCL.::GO:0048147; P:negative regulation of fibroblast proliferation; ISS:BHF-UCL.::GO:0045787; P:positive regulation of cell cycle; IDA:BHF-UCL.::GO:0030307; P:positive regulation of cell growth; IDA:BHF-UCL.::GO:0030335; P:positive regulation of cell migration; IDA:BHF-UCL.::GO:0050769; P:positive regulation of neurogenesis; ISS:BHF-UCL.::GO:0045666; P:positive regulation of neuron differentiation; ISS:BHF-UCL.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:BHF-UCL.::GO:0045732; P:positive regulation of protein catabolic process; ISS:BHF-UCL.::GO:0045862; P:positive regulation of proteolysis; IDA:BHF-UCL.::GO:0000209; P:protein polyubiquitination; IDA:BHF-UCL.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0034612; P:response to tumor necrosis factor; ISS:BHF-UCL.::GO:0009411; P:response to UV; ISS:BHF-UCL. |