rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
481 | D4A723 | 203 | RN152_RAT E3 ubiquitin-protein ligase RNF152 ... | 53 | 1.3 | 34.3 | 30 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB. | 482 | Q5A4X0 | 681 | BRE1_CANAL E3 ubiquitin-protein ligase BRE1 O... | 40 | 1.3 | 35.4 | 38 | 50 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0030447; P:filamentous growth; IMP:CGD. | 483 | Q9C8E1 | 622 | ORTH4_ARATH Putative E3 ubiquitin-protein lig... | 42 | 3.9 | 33.5 | 36 | 48 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0008327; F:methyl-CpG binding; ISS:UniProtKB.::GO:0010428; F:methyl-CpNpG binding; ISS:UniProtKB.::GO:0010429; F:methyl-CpNpN binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0010424; P:DNA methylation on cytosine within a CG sequence; ISS:UniProtKB. | 484 | Q7X843 | 349 | ATL48_ARATH RING-H2 finger protein ATL48 OS=A... | 51 | 1.3 | 35 | 35 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 485 | Q680I0 | 623 | ORTH5_ARATH E3 ubiquitin-protein ligase ORTHR... | 42 | 3.8 | 33.9 | 36 | 48 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0008327; F:methyl-CpG binding; ISS:UniProtKB.::GO:0010428; F:methyl-CpNpG binding; ISS:UniProtKB.::GO:0010429; F:methyl-CpNpN binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0090309; P:positive regulation of methylation-dependent chromatin silencing; IMP:UniProtKB. | 486 | Q4R7K7 | 1001 | BRE1B_MACFA E3 ubiquitin-protein ligase BRE1B... | 41 | 1.3 | 35.4 | 37 | 46 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0010390; P:histone monoubiquitination; ISS:UniProtKB. | 487 | Q91187 | 1073 | RAG1_ONCMY V(D)J recombination-activating pro... | 39 | 1.4 | 35.4 | 38 | 54 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0004519; F:endonuclease activity; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0030183; P:B cell differentiation; ISS:UniProtKB.::GO:0010390; P:histone monoubiquitination; ISS:UniProtKB.::GO:0033077; P:T cell differentiation in thymus; ISS:UniProtKB.::GO:0033151; P:V(D)J recombination; ISS:UniProtKB. | 488 | Q6J2U6 | 229 | RN114_RAT RING finger protein 114 OS=Rattus n... | 43 | 1.4 | 34.7 | 35 | 53 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW. | 489 | E1C2W7 | 203 | RN152_CHICK E3 ubiquitin-protein ligase RNF15... | 53 | 1.4 | 34.3 | 30 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB. | 490 | Q60MF5 | 836 | RN207_CAEBR Probable RING finger protein 207 ... | 29 | 1.4 | 35 | 41 | 59 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 491 | Q68EV7 | 203 | R152B_XENLA E3 ubiquitin-protein ligase rnf15... | 53 | 1.4 | 34.3 | 30 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB. | 492 | Q9ET26 | 229 | RN114_MOUSE RING finger protein 114 OS=Mus mu... | 43 | 1.5 | 34.3 | 35 | 53 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW. | 493 | A8WWR3 | 578 | HRDL1_CAEBR E3 ubiquitin-protein ligase hrd-l... | 40 | 1.5 | 35 | 40 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0043526; P:neuroprotection; ISS:UniProtKB. | 494 | B5DF45 | 530 | TRAF6_RAT TNF receptor-associated factor 6 OS... | 65 | 1.5 | 35 | 34 | 49 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070498; P:interleukin-1-mediated signaling pathway; IMP:RGD.::GO:0007254; P:JNK cascade; IMP:RGD.::GO:0048661; P:positive regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:RGD.::GO:0006461; P:protein complex assembly; IMP:RGD.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro. | 495 | Q8CJB9 | 1002 | BRE1B_RAT E3 ubiquitin-protein ligase BRE1B O... | 41 | 1.5 | 35 | 37 | 46 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019717; C:synaptosome; IDA:RGD. | | | | | | | | | | GO:0032403; F:protein complex binding; IDA:RGD.::GO:0017075; F:syntaxin-1 binding; IPI:RGD.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:RGD. | 496 | A6NI03 | 449 | TR64B_HUMAN Putative tripartite motif-contain... | 68 | 1.5 | 35 | 26 | 46 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 497 | Q3ZCC3 | 542 | TRAF6_BOVIN TNF receptor-associated factor 6 ... | 194 | 1.5 | 35 | 23 | 34 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro. | 498 | P93030 | 193 | RMA2_ARATH E3 ubiquitin-protein ligase RMA2 O... | 65 | 1.6 | 33.9 | 28 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005515; F:protein binding; IPI:TAIR.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 499 | P70196 | 530 | TRAF6_MOUSE TNF receptor-associated factor 6 ... | 65 | 1.6 | 35 | 34 | 49 | GO:0035631; C:CD40 receptor complex; IDA:BHF-UCL.::GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0009898; C:internal side of plasma membrane; IDA:BHF-UCL.::GO:0005624; C:membrane fraction; IDA:UniProtKB. | | | | | | | | | | GO:0004871; F:signal transducer activity; TAS:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; IMP:MGI.::GO:0045453; P:bone resorption; IMP:UniProtKB.::GO:0048468; P:cell development; IMP:MGI.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0070498; P:interleukin-1-mediated signaling pathway; IMP:UniProtKB.::GO:0043011; P:myeloid dendritic cell differentiation; IMP:MGI.::GO:0001843; P:neural tube closure; IMP:UniProtKB.::GO:0042475; P:odontogenesis of dentin-containing tooth; IMP:MGI.::GO:0001503; P:ossification; IMP:MGI.::GO:0030316; P:osteoclast differentiation; IMP:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0045084; P:positive regulation of interleukin-12 biosynthetic process; IMP:MGI.::GO:0045410; P:positive regulation of interleukin-6 biosynthetic process; IMP:MGI.::GO:0031666; P:positive regulation of lipopolysaccharide-mediated signaling pathway; IMP:UniProtKB.::GO:0042102; P:positive regulation of T cell proliferation; IMP:UniProtKB.::GO:0051865; P:protein autoubiquitination; TAS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.::GO:0051023; P:regulation of immunoglobulin secretion; IDA:MGI.::GO:0042088; P:T-helper 1 type immune response; IMP:MGI. | 500 | Q3U319 | 1001 | BRE1B_MOUSE E3 ubiquitin-protein ligase BRE1B... | 41 | 1.6 | 35 | 37 | 46 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 501 | P40072 | 274 | SLX8_YEAST E3 ubiquitin-protein ligase comple... | 48 | 1.7 | 34.3 | 31 | 50 | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0016925; P:protein sumoylation; IMP:SGD.::GO:0000723; P:telomere maintenance; IMP:SGD. | 502 | Q13114 | 568 | TRAF3_HUMAN TNF receptor-associated factor 3 ... | 65 | 1.7 | 34.7 | 32 | 48 | GO:0035631; C:CD40 receptor complex; ISS:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0009898; C:internal side of plasma membrane; ISS:BHF-UCL.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; TAS:ProtInc.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.::GO:0050688; P:regulation of defense response to virus; ISS:UniProtKB.::GO:0032648; P:regulation of interferon-beta production; ISS:UniProtKB.::GO:0030162; P:regulation of proteolysis; IMP:UniProtKB.::GO:0002224; P:toll-like receptor signaling pathway; ISS:UniProtKB.::GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IMP:UniProtKB. | 503 | Q2U6E8 | 819 | SLX4_ASPOR Structure-specific endonuclease su... | 76 | 1.7 | 35 | 33 | 54 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 504 | Q9SLC4 | 217 | ATL40_ARATH RING-H2 finger protein ATL40 OS=A... | 60 | 1.8 | 33.9 | 30 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 505 | Q1JPS1 | 232 | PCF5B_DANRE Polycomb group RING finger protei... | 62 | 1.8 | 34.3 | 34 | 40 | GO:0031519; C:PcG protein complex; ISS:UniProtKB. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 506 | Q8L649 | 248 | BB_ARATH E3 ubiquitin ligase BIG BROTHER OS=A... | 44 | 1.8 | 34.3 | 34 | 52 | | | | | | | | | | | GO:0031624; F:ubiquitin conjugating enzyme binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0048437; P:floral organ development; IMP:TAIR.::GO:0046621; P:negative regulation of organ growth; IMP:TAIR.::GO:0051865; P:protein autoubiquitination; IDA:TAIR. | 507 | P09309 | 467 | IE61_VZVD E3 ubiquitin-protein ligase IE61 OS... | 24 | 1.8 | 34.7 | 54 | 63 | | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 508 | Q60803 | 567 | TRAF3_MOUSE TNF receptor-associated factor 3 ... | 65 | 1.9 | 34.7 | 31 | 49 | GO:0035631; C:CD40 receptor complex; IDA:BHF-UCL.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0009898; C:internal side of plasma membrane; IDA:BHF-UCL. | | | | | | | | | | GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.::GO:0050688; P:regulation of defense response to virus; IMP:UniProtKB.::GO:0032648; P:regulation of interferon-beta production; IMP:UniProtKB.::GO:0030162; P:regulation of proteolysis; IDA:UniProtKB.::GO:0002224; P:toll-like receptor signaling pathway; IMP:UniProtKB.::GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IMP:UniProtKB. | 509 | B2RYR0 | 564 | RN168_RAT E3 ubiquitin-protein ligase RNF168 ... | 41 | 1.9 | 34.7 | 29 | 56 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0070535; P:histone H2A K63-linked ubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB. | 510 | Q757D9 | 643 | BRE1_ASHGO E3 ubiquitin-protein ligase BRE1 O... | 39 | 2 | 34.7 | 33 | 51 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW. | 511 | P79051 | 861 | RHP16_SCHPO ATP-dependent helicase rhp16 OS=S... | 43 | 2 | 34.7 | 30 | 49 | GO:0000109; C:nucleotide-excision repair complex; IPI:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0034644; P:cellular response to UV; IGI:PomBase.::GO:0006289; P:nucleotide-excision repair; IGI:PomBase. |