| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P37061 | 446 | NAOX_ENTFA NADH oxidase OS=Enterococcus faeca... | 131 | 0.00003 | 48.9 | 29 | 46 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0003954; F:NADH dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 2 | P39051 | 492 | TYTR_TRYBB Trypanothione reductase OS=Trypano... | 176 | 0.00008 | 47.4 | 24 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015036; F:disulfide oxidoreductase activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015042; F:trypanothione-disulfide reductase activity; IEA:EC. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 3 | Q2SIP2 | 464 | STHA_HAHCH Soluble pyridine nucleotide transh... | 149 | 0.0001 | 47.4 | 29 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0003957; F:NAD(P)+ transhydrogenase (B-specific) activity; IEA:EC. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 4 | Q6P6R2 | 509 | DLDH_RAT Dihydrolipoyl dehydrogenase, mitocho... | 158 | 0.001 | 43.9 | 27 | 44 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0045252; C:oxoglutarate dehydrogenase complex; IDA:RGD.::GO:0045254; C:pyruvate dehydrogenase complex; IDA:RGD. | | | | | | | | | | GO:0004148; F:dihydrolipoyl dehydrogenase activity; IDA:RGD.::GO:0050660; F:flavin adenine dinucleotide binding; IDA:RGD.::GO:0043544; F:lipoamide binding; IDA:RGD.::GO:0051287; F:NAD binding; IDA:RGD. | | | | | | | | | | GO:0006103; P:2-oxoglutarate metabolic process; IDA:RGD.::GO:0006086; P:acetyl-CoA biosynthetic process from pyruvate; IDA:RGD.::GO:0007568; P:aging; IEP:RGD.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0051068; P:dihydrolipoamide metabolic process; IDA:RGD.::GO:0009106; P:lipoate metabolic process; IDA:RGD. | 5 | P28593 | 492 | TYTR_TRYCR Trypanothione reductase OS=Trypano... | 171 | 0.002 | 43.1 | 25 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015036; F:disulfide oxidoreductase activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015042; F:trypanothione-disulfide reductase activity; IEA:EC. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 6 | O34324 | 458 | DLDH3_BACSU Dihydrolipoyl dehydrogenase OS=Ba... | 152 | 0.003 | 42.7 | 26 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004148; F:dihydrolipoyl dehydrogenase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0045150; P:acetoin catabolic process; IEA:UniProtKB-KW.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 7 | O08749 | 509 | DLDH_MOUSE Dihydrolipoyl dehydrogenase, mitoc... | 158 | 0.004 | 42 | 27 | 44 | GO:0043159; C:acrosomal matrix; IDA:MGI.::GO:0019861; C:flagellum; IDA:MGI.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004148; F:dihydrolipoyl dehydrogenase activity; IMP:MGI.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0007369; P:gastrulation; IMP:MGI.::GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; IMP:MGI.::GO:0006508; P:proteolysis; IDA:MGI.::GO:0042391; P:regulation of membrane potential; IMP:MGI.::GO:0048240; P:sperm capacitation; IDA:MGI. | 8 | Q60HG3 | 509 | DLDH_MACFA Dihydrolipoyl dehydrogenase, mitoc... | 158 | 0.004 | 42 | 26 | 44 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004148; F:dihydrolipoyl dehydrogenase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 9 | P09622 | 509 | DLDH_HUMAN Dihydrolipoyl dehydrogenase, mitoc... | 158 | 0.005 | 42 | 26 | 44 | GO:0005759; C:mitochondrial matrix; TAS:Reactome. | | | | | | | | | | GO:0004148; F:dihydrolipoyl dehydrogenase activity; TAS:ProtInc. | | | | | | | | | | GO:0009083; P:branched chain family amino acid catabolic process; TAS:Reactome.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006554; P:lysine catabolic process; TAS:Reactome.::GO:0010510; P:regulation of acetyl-CoA biosynthetic process from pyruvate; TAS:Reactome.::GO:0006099; P:tricarboxylic acid cycle; TAS:Reactome. | 10 | Q5R4B1 | 509 | DLDH_PONAB Dihydrolipoyl dehydrogenase, mitoc... | 158 | 0.006 | 41.6 | 26 | 44 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004148; F:dihydrolipoyl dehydrogenase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 11 | Q8CIZ7 | 509 | DLDH_CRIGR Dihydrolipoyl dehydrogenase, mitoc... | 158 | 0.006 | 41.6 | 27 | 44 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004148; F:dihydrolipoyl dehydrogenase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 12 | A0KEJ2 | 388 | NORW_AERHH Nitric oxide reductase FlRd-NAD(+)... | 205 | 0.007 | 41.2 | 29 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016731; F:oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | | 13 | P00393 | 434 | DHNA_ECOLI NADH dehydrogenase OS=Escherichia ... | 120 | 0.009 | 40.8 | 30 | 46 | GO:0044459; C:plasma membrane part; IPI:EcoCyc. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IDA:EcoCyc.::GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IDA:EcoCyc. | | | | | | | | | | GO:0019646; P:aerobic electron transport chain; IDA:EcoCyc.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 14 | P49819 | 509 | DLDH_CANFA Dihydrolipoyl dehydrogenase, mitoc... | 158 | 0.011 | 40.8 | 27 | 45 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004148; F:dihydrolipoyl dehydrogenase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 15 | Q2YWW1 | 438 | CDR_STAAB Coenzyme A disulfide reductase OS=S... | 90 | 0.013 | 40.4 | 30 | 51 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0050451; F:CoA-disulfide reductase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006467; P:protein thiol-disulfide exchange; IEA:InterPro. | 16 | P09623 | 509 | DLDH_PIG Dihydrolipoyl dehydrogenase, mitocho... | 158 | 0.016 | 40.4 | 25 | 43 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004148; F:dihydrolipoyl dehydrogenase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 17 | Q9BRQ8 | 373 | AIFM2_HUMAN Apoptosis-inducing factor 2 OS=Ho... | 111 | 0.019 | 40 | 30 | 49 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005811; C:lipid particle; IDA:UniProtKB.::GO:0005741; C:mitochondrial outer membrane; IDA:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IDA:UniProtKB.::GO:0004174; F:electron-transferring-flavoprotein dehydrogenase activity; IDA:UniProtKB.::GO:0050660; F:flavin adenine dinucleotide binding; IDA:UniProtKB. | | | | | | | | | | GO:0008637; P:apoptotic mitochondrial changes; NAS:UniProtKB.::GO:0030261; P:chromosome condensation; IDA:UniProtKB.::GO:0006917; P:induction of apoptosis; IMP:UniProtKB. | 18 | Q811C4 | 479 | DLDH_MESAU Dihydrolipoyl dehydrogenase, mitoc... | 158 | 0.023 | 39.7 | 26 | 44 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004148; F:dihydrolipoyl dehydrogenase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 19 | Q56839 | 523 | XECC_XANP2 2-oxopropyl-CoM reductase, carboxy... | 93 | 0.025 | 39.7 | 31 | 49 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0050628; F:2-oxopropyl-CoM reductase (carboxylating) activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 20 | A5IRE8 | 438 | CDR_STAA9 Coenzyme A disulfide reductase OS=S... | 78 | 0.03 | 39.3 | 31 | 54 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0050451; F:CoA-disulfide reductase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006467; P:protein thiol-disulfide exchange; IEA:InterPro. | 21 | A6U077 | 438 | CDR_STAA2 Coenzyme A disulfide reductase OS=S... | 78 | 0.03 | 39.3 | 31 | 54 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0050451; F:CoA-disulfide reductase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006467; P:protein thiol-disulfide exchange; IEA:InterPro. | 22 | Q96NN9 | 605 | AIFM3_HUMAN Apoptosis-inducing factor 3 OS=Ho... | 174 | 0.033 | 39.3 | 25 | 41 | GO:0005783; C:endoplasmic reticulum; IDA:HGNC.::GO:0005743; C:mitochondrial inner membrane; IDA:HGNC. | | | | | | | | | | GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; IDA:HGNC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008635; P:activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; IDA:HGNC.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IDA:HGNC.::GO:0051882; P:mitochondrial depolarization; IDA:HGNC.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 23 | A1U1Y5 | 463 | STHA_MARAV Soluble pyridine nucleotide transh... | 149 | 0.035 | 39.3 | 28 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0003957; F:NAD(P)+ transhydrogenase (B-specific) activity; IEA:EC. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 24 | Q42711 | 434 | MDARS_CUCSA Monodehydroascorbate reductase, s... | 73 | 0.037 | 38.9 | 33 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016656; F:monodehydroascorbate reductase (NADH) activity; IEA:EC. | | | | | | | | | | | 25 | Q8CPT6 | 438 | CDR_STAES Coenzyme A disulfide reductase OS=S... | 82 | 0.039 | 38.9 | 30 | 48 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0050451; F:CoA-disulfide reductase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006467; P:protein thiol-disulfide exchange; IEA:InterPro. | 26 | Q5HQI9 | 438 | CDR_STAEQ Coenzyme A disulfide reductase OS=S... | 82 | 0.039 | 38.9 | 30 | 48 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0050451; F:CoA-disulfide reductase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006467; P:protein thiol-disulfide exchange; IEA:InterPro. | 27 | P11959 | 470 | DLDH1_GEOSE Dihydrolipoyl dehydrogenase OS=Ge... | 155 | 0.04 | 38.9 | 26 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004148; F:dihydrolipoyl dehydrogenase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 28 | Q4L4Y7 | 440 | CDR_STAHJ Coenzyme A disulfide reductase OS=S... | 90 | 0.04 | 38.9 | 30 | 48 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0050451; F:CoA-disulfide reductase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006467; P:protein thiol-disulfide exchange; IEA:InterPro. | 29 | Q8NXE8 | 438 | CDR_STAAW Coenzyme A disulfide reductase OS=S... | 78 | 0.046 | 38.9 | 31 | 53 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0050451; F:CoA-disulfide reductase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006467; P:protein thiol-disulfide exchange; IEA:InterPro. | 30 | Q6GAV6 | 438 | CDR_STAAS Coenzyme A disulfide reductase OS=S... | 78 | 0.046 | 38.9 | 31 | 53 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0050451; F:CoA-disulfide reductase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006467; P:protein thiol-disulfide exchange; IEA:InterPro. | 31 | Q7A6H1 | 438 | CDR_STAAN Coenzyme A disulfide reductase OS=S... | 78 | 0.047 | 38.9 | 31 | 53 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0050451; F:CoA-disulfide reductase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006467; P:protein thiol-disulfide exchange; IEA:InterPro. |
