rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | P35858 | 605 | ALS_HUMAN Insulin-like growth factor-binding ... | 424 | 0.0004 | 48.9 | 26 | 39 | GO:0005615; C:extracellular space; TAS:ProtInc.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005625; C:soluble fraction; TAS:ProtInc. | | | | | | | | | | GO:0005520; F:insulin-like growth factor binding; TAS:ProtInc. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; TAS:ProtInc. | 92 | P0C7J6 | 766 | LRFN1_RAT Leucine-rich repeat and fibronectin... | 298 | 0.0004 | 48.9 | 26 | 41 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 93 | A6QLV3 | 582 | SHOC2_BOVIN Leucine-rich repeat protein SHOC-... | 449 | 0.0004 | 48.9 | 26 | 43 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000164; C:protein phosphatase type 1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0019903; F:protein phosphatase binding; ISS:UniProtKB. | | | | | | | | | | GO:0046579; P:positive regulation of Ras protein signal transduction; ISS:UniProtKB. | 94 | Q5RAV5 | 582 | SHOC2_PONAB Leucine-rich repeat protein SHOC-... | 449 | 0.0005 | 48.9 | 26 | 43 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000164; C:protein phosphatase type 1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0019903; F:protein phosphatase binding; ISS:UniProtKB. | | | | | | | | | | GO:0046579; P:positive regulation of Ras protein signal transduction; ISS:UniProtKB. | 95 | Q9UQ13 | 582 | SHOC2_HUMAN Leucine-rich repeat protein SHOC-... | 449 | 0.0005 | 48.9 | 26 | 43 | GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0000164; C:protein phosphatase type 1 complex; IDA:UniProtKB. | | | | | | | | | | GO:0019903; F:protein phosphatase binding; IDA:UniProtKB.::GO:0019888; F:protein phosphatase regulator activity; TAS:UniProtKB. | | | | | | | | | | GO:0008543; P:fibroblast growth factor receptor signaling pathway; NAS:UniProtKB.::GO:0046579; P:positive regulation of Ras protein signal transduction; IMP:UniProtKB.::GO:0007265; P:Ras protein signal transduction; NAS:UniProtKB. | 96 | P08678 | 2026 | CYAA_YEAST Adenylate cyclase OS=Saccharomyces... | 206 | 0.061 | 42.4 | 26 | 45 | GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:SGD. | | | | | | | | | | GO:0004016; F:adenylate cyclase activity; IDA:SGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 97 | Q3MHH9 | 680 | ECM2_BOVIN Extracellular matrix protein 2 OS=... | 310 | 0.013 | 44.3 | 23 | 43 | GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 98 | Q8NEP3 | 725 | DAAF1_HUMAN Dynein assembly factor 1, axonema... | 154 | 0.97 | 38.1 | 26 | 44 | GO:0035085; C:cilium axoneme; IDA:UniProtKB.::GO:0005737; C:cytoplasm; NAS:BHF-UCL.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0045502; F:dynein binding; IMP:UniProtKB. | | | | | | | | | | GO:0070286; P:axonemal dynein complex assembly; IMP:UniProtKB.::GO:0003341; P:cilium movement; IMP:BHF-UCL.::GO:0044458; P:motile cilium assembly; IMP:BHF-UCL. | 99 | O61967 | 699 | LAP1_CAEEL Protein lap1 OS=Caenorhabditis ele... | 396 | 0.006 | 45.1 | 24 | 37 | GO:0005912; C:adherens junction; IDA:UniProtKB.::GO:0016323; C:basolateral plasma membrane; IDA:WormBase. | | | | | | | | | | | | | | | | | | | | GO:0030029; P:actin filament-based process; IMP:WormBase.::GO:0007155; P:cell adhesion; IMP:WormBase.::GO:0007043; P:cell-cell junction assembly; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0007163; P:establishment or maintenance of cell polarity; IEP:UniProtKB.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:WormBase.::GO:0030728; P:ovulation; IMP:WormBase.::GO:0060465; P:pharynx development; IMP:WormBase.::GO:0015031; P:protein transport; IEP:UniProtKB.::GO:0045108; P:regulation of intermediate filament polymerization or depolymerization; IMP:UniProtKB. | 100 | Q8AVI4 | 577 | SHOC2_XENLA Leucine-rich repeat protein SHOC-... | 451 | 0.0007 | 48.1 | 25 | 40 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000164; C:protein phosphatase type 1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0019903; F:protein phosphatase binding; ISS:UniProtKB. | | | | | | | | | | GO:0046579; P:positive regulation of Ras protein signal transduction; ISS:UniProtKB. | 101 | P07359 | 626 | GP1BA_HUMAN Platelet glycoprotein Ib alpha ch... | 203 | 0.18 | 40.4 | 29 | 42 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005624; C:membrane fraction; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0015057; F:thrombin receptor activity; TAS:UniProtKB. | | | | | | | | | | GO:0007597; P:blood coagulation, intrinsic pathway; TAS:Reactome.::GO:0007155; P:cell adhesion; IDA:MGI.::GO:0042730; P:fibrinolysis; IDA:UniProtKB.::GO:0030168; P:platelet activation; TAS:UniProtKB. | 102 | Q6UXM1 | 1119 | LRIG3_HUMAN Leucine-rich repeats and immunogl... | 399 | 0.0008 | 48.5 | 25 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 103 | P47853 | 369 | PGS1_RAT Biglycan OS=Rattus norvegicus (Rat).... | 301 | 0.0008 | 47.8 | 25 | 41 | GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0001974; P:blood vessel remodeling; IEP:RGD. | 104 | Q9GL65 | 841 | TLR4_BOVIN Toll-like receptor 4 OS=Bos taurus... | 178 | 0.0009 | 48.1 | 28 | 45 | GO:0005622; C:intracellular; IEA:InterPro.::GO:0046696; C:lipopolysaccharide receptor complex; ISS:UniProtKB. | | | | | | | | | | GO:0001875; F:lipopolysaccharide receptor activity; ISS:UniProtKB.::GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro. | | | | | | | | | | GO:0032497; P:detection of lipopolysaccharide; ISS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0042116; P:macrophage activation; ISS:UniProtKB. | 105 | B0M0P8 | 2356 | GEFL_DICDI Ras guanine nucleotide exchange fa... | 224 | 0.0009 | 48.5 | 28 | 40 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0017048; F:Rho GTPase binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.::GO:0046956; P:positive phototaxis; IMP:dictyBase.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0030587; P:sorocarp development; IMP:dictyBase.::GO:0043052; P:thermotaxis; IMP:dictyBase. | 106 | B5DX45 | 629 | SUR8_DROPS Leucine-rich repeat protein soc-2 ... | 424 | 0.001 | 47.8 | 23 | 43 | | | | | | | | | | | | | | | | | | | | | | 107 | Q9Z2H4 | 951 | LGR4_RAT Leucine-rich repeat-containing G-pro... | 356 | 0.001 | 48.1 | 30 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016500; F:protein-hormone receptor activity; IEA:InterPro. | | | | | | | | | | | 108 | Q24020 | 1256 | FLII_DROME Protein flightless-1 OS=Drosophila... | 395 | 0.14 | 41.2 | 26 | 40 | | | | | | | | | | | GO:0003779; F:actin binding; ISS:FlyBase. | | | | | | | | | | GO:0007527; P:adult somatic muscle development; IMP:FlyBase.::GO:0007629; P:flight behavior; IMP:FlyBase.::GO:0010004; P:gastrulation involving germ band extension; IMP:FlyBase.::GO:0030239; P:myofibril assembly; IMP:FlyBase. | 109 | P21809 | 369 | PGS1_BOVIN Biglycan OS=Bos taurus (Bovine). G... | 232 | 0.001 | 47.4 | 25 | 41 | GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell.::GO:0030133; C:transport vesicle; ISS:AgBase. | | | | | | | | | | | | | | | | | | | | | 110 | P21810 | 368 | PGS1_HUMAN Biglycan OS=Homo sapiens (Human). ... | 232 | 0.001 | 47.4 | 25 | 41 | GO:0005578; C:proteinaceous extracellular matrix; NAS:UniProtKB.::GO:0030133; C:transport vesicle; IDA:LIFEdb. | | | | | | | | | | GO:0005201; F:extracellular matrix structural constituent; NAS:UniProtKB. | | | | | | | | | | | 111 | P28653 | 369 | PGS1_MOUSE Biglycan OS=Mus musculus (Mouse). ... | 301 | 0.001 | 47.4 | 25 | 41 | GO:0009986; C:cell surface; IDA:MGI.::GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell.::GO:0042383; C:sarcolemma; IDA:MGI. | | | | | | | | | | GO:0050840; F:extracellular matrix binding; IDA:MGI.::GO:0005539; F:glycosaminoglycan binding; IDA:MGI. | | | | | | | | | | GO:0019800; P:peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan; IDA:MGI. | 112 | O02678 | 369 | PGS1_CANFA Biglycan OS=Canis familiaris (Dog)... | 221 | 0.001 | 47 | 26 | 42 | GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 113 | Q6AYI5 | 582 | SHOC2_RAT Leucine-rich repeat protein SHOC-2 ... | 449 | 0.001 | 47.4 | 26 | 43 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000164; C:protein phosphatase type 1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0019903; F:protein phosphatase binding; ISS:UniProtKB. | | | | | | | | | | GO:0046579; P:positive regulation of Ras protein signal transduction; ISS:UniProtKB. | 114 | Q6P3Y9 | 568 | PONL1_MOUSE Podocan-like protein 1 OS=Mus mus... | 371 | 0.001 | 47.4 | 26 | 41 | GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 115 | Q1L8Y7 | 561 | SHOC2_DANRE Leucine-rich repeat protein SHOC-... | 411 | 0.001 | 47.4 | 25 | 42 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000164; C:protein phosphatase type 1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0019903; F:protein phosphatase binding; ISS:UniProtKB. | | | | | | | | | | GO:0046579; P:positive regulation of Ras protein signal transduction; ISS:UniProtKB. | 116 | O02833 | 605 | ALS_PAPHA Insulin-like growth factor-binding ... | 187 | 0.091 | 41.6 | 28 | 47 | GO:0005615; C:extracellular space; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 117 | Q9D5E4 | 523 | LRC48_MOUSE Leucine-rich repeat-containing pr... | 158 | 0.061 | 42 | 27 | 47 | | | | | | | | | | | | | | | | | | | | | | 118 | Q4V8I7 | 810 | LRC8A_RAT Leucine-rich repeat-containing prot... | 281 | 0.002 | 47.4 | 26 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | GO:0002329; P:pre-B cell differentiation; ISS:UniProtKB. | 119 | O88520 | 582 | SHOC2_MOUSE Leucine-rich repeat protein SHOC-... | 449 | 0.002 | 47 | 26 | 43 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000164; C:protein phosphatase type 1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0019903; F:protein phosphatase binding; ISS:UniProtKB. | | | | | | | | | | GO:0046579; P:positive regulation of Ras protein signal transduction; ISS:UniProtKB. | 120 | O46390 | 369 | PGS1_SHEEP Biglycan OS=Ovis aries (Sheep). GN... | 232 | 0.002 | 46.6 | 25 | 41 | GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 121 | P14605 | 1692 | CYAA_SCHPO Adenylate cyclase OS=Schizosacchar... | 187 | 1 | 38.1 | 25 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; NAS:PomBase. | | | | | | | | | | GO:0004016; F:adenylate cyclase activity; IMP:PomBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007188; P:G-protein signaling, coupled to cAMP nucleotide second messenger; NAS:PomBase.::GO:0045014; P:negative regulation of transcription by glucose; TAS:PomBase.::GO:0031137; P:regulation of conjugation with cellular fusion; NAS:PomBase. |