rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
121 | P14605 | 1692 | CYAA_SCHPO Adenylate cyclase OS=Schizosacchar... | 187 | 1 | 38.1 | 25 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; NAS:PomBase. | | | | | | | | | | GO:0004016; F:adenylate cyclase activity; IMP:PomBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007188; P:G-protein signaling, coupled to cAMP nucleotide second messenger; NAS:PomBase.::GO:0045014; P:negative regulation of transcription by glucose; TAS:PomBase.::GO:0031137; P:regulation of conjugation with cellular fusion; NAS:PomBase. | 122 | Q80WG5 | 810 | LRC8A_MOUSE Leucine-rich repeat-containing pr... | 281 | 0.002 | 47 | 26 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | GO:0002329; P:pre-B cell differentiation; IMP:UniProtKB. | 123 | Q6GPJ8 | 807 | CEP97_XENLA Centrosomal protein of 97 kDa OS=... | 182 | 0.002 | 47 | 25 | 48 | GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 124 | P23799 | 630 | ESAG8_TRYBB Putative adenylate cyclase regula... | 320 | 0.016 | 43.9 | 24 | 40 | | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006171; P:cAMP biosynthetic process; IEA:UniProtKB-KW. | 125 | A2AL36 | 2334 | CNTRL_MOUSE Centriolin OS=Mus musculus (Mouse... | 154 | 0.72 | 38.9 | 25 | 44 | | | | | | | | | | | | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW. | 126 | O46403 | 372 | PGS1_HORSE Biglycan OS=Equus caballus (Horse)... | 231 | 0.003 | 45.8 | 25 | 42 | GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 127 | Q9BTN0 | 628 | LRFN3_HUMAN Leucine-rich repeat and fibronect... | 204 | 0.003 | 46.2 | 30 | 48 | GO:0030424; C:axon; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 128 | Q5R6B1 | 522 | LRRT1_PONAB Leucine-rich repeat transmembrane... | 224 | 0.003 | 45.8 | 26 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 129 | Q5RF01 | 662 | LRC32_PONAB Leucine-rich repeat-containing pr... | 279 | 0.004 | 45.8 | 27 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 130 | Q28256 | 677 | GP1BA_CANFA Platelet glycoprotein Ib alpha ch... | 180 | 0.004 | 45.8 | 28 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 131 | D2HFT7 | 628 | LRFN3_AILME Leucine-rich repeat and fibronect... | 204 | 0.004 | 45.8 | 29 | 48 | GO:0030424; C:axon; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 132 | Q5RFE9 | 602 | LRC40_PONAB Leucine-rich repeat-containing pr... | 282 | 0.004 | 45.8 | 28 | 48 | | | | | | | | | | | | | | | | | | | | | | 133 | Q4R3P6 | 602 | LRC40_MACFA Leucine-rich repeat-containing pr... | 282 | 0.005 | 45.8 | 28 | 48 | | | | | | | | | | | | | | | | | | | | | | 134 | Q96JA1 | 1093 | LRIG1_HUMAN Leucine-rich repeats and immunogl... | 385 | 0.005 | 45.8 | 26 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 135 | P28675 | 357 | PGS2_CHICK Decorin OS=Gallus gallus (Chicken)... | 260 | 0.005 | 45.1 | 25 | 41 | GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 136 | B0BNK7 | 626 | LRFN3_RAT Leucine-rich repeat and fibronectin... | 204 | 0.005 | 45.4 | 29 | 48 | GO:0030424; C:axon; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 137 | Q9P244 | 771 | LRFN1_HUMAN Leucine-rich repeat and fibronect... | 298 | 0.005 | 45.8 | 25 | 41 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 138 | P0C895 | 374 | Y2010_ARATH LRR repeats and ubiquitin-like do... | 206 | 0.005 | 45.1 | 29 | 46 | | | | | | | | | | | | | | | | | | | | | | 139 | A4D1F6 | 860 | LRRD1_HUMAN Leucine-rich repeat and death dom... | 105 | 0.005 | 45.8 | 38 | 50 | | | | | | | | | | | | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 140 | Q9DE68 | 356 | PGS2_COTJA Decorin OS=Coturnix coturnix japon... | 260 | 0.005 | 45.1 | 25 | 41 | GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 141 | Q3V1N1 | 1048 | MFHA1_MOUSE Malignant fibrous histiocytoma-am... | 203 | 3.9 | 36.2 | 29 | 44 | | | | | | | | | | | | | | | | | | | | | | 142 | O00206 | 839 | TLR4_HUMAN Toll-like receptor 4 OS=Homo sapie... | 187 | 0.006 | 45.4 | 29 | 47 | GO:0009897; C:external side of plasma membrane; IDA:BHF-UCL.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0046696; C:lipopolysaccharide receptor complex; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0001530; F:lipopolysaccharide binding; NAS:UniProtKB.::GO:0001875; F:lipopolysaccharide receptor activity; IDA:UniProtKB.::GO:0004888; F:transmembrane signaling receptor activity; NAS:UniProtKB. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; ISS:BHF-UCL.::GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0050829; P:defense response to Gram-negative bacterium; IC:BHF-UCL.::GO:0016046; P:detection of fungus; NAS:UniProtKB.::GO:0032497; P:detection of lipopolysaccharide; IDA:UniProtKB.::GO:0007252; P:I-kappaB phosphorylation; IDA:BHF-UCL.::GO:0045087; P:innate immune response; TAS:BHF-UCL.::GO:0060729; P:intestinal epithelial structure maintenance; ISS:BHF-UCL.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; ISS:BHF-UCL.::GO:0032689; P:negative regulation of interferon-gamma production; ISS:BHF-UCL.::GO:0032700; P:negative regulation of interleukin-17 production; ISS:BHF-UCL.::GO:0032707; P:negative regulation of interleukin-23 production; ISS:BHF-UCL.::GO:0032715; P:negative regulation of interleukin-6 production; ISS:BHF-UCL.::GO:0045671; P:negative regulation of osteoclast differentiation; NAS:UniProtKB.::GO:0032720; P:negative regulation of tumor necrosis factor production; ISS:BHF-UCL.::GO:0032722; P:positive regulation of chemokine production; IDA:BHF-UCL.::GO:0050729; P:positive regulation of inflammatory response; IC:BHF-UCL.::GO:0032727; P:positive regulation of interferon-alpha production; ISS:BHF-UCL.::GO:0032728; P:positive regulation of interferon-beta production; ISS:BHF-UCL.::GO:0032729; P:positive regulation of interferon-gamma production; ISS:BHF-UCL.::GO:0032732; P:positive regulation of interleukin-1 production; ISS:BHF-UCL.::GO:0032733; P:positive regulation of interleukin-10 production; ISS:BHF-UCL.::GO:0045084; P:positive regulation of interleukin-12 biosynthetic process; IDA:UniProtKB.::GO:0032735; P:positive regulation of interleukin-12 production; ISS:BHF-UCL.::GO:0032755; P:positive regulation of interleukin-6 production; IDA:BHF-UCL.::GO:0045416; P:positive regulation of interleukin-8 biosynthetic process; IDA:UniProtKB.::GO:0032757; P:positive regulation of interleukin-8 production; IDA:BHF-UCL.::GO:0042346; P:positive regulation of NF-kappaB import into nucleus; IDA:BHF-UCL.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:MGI.::GO:0051770; P:positive regulation of nitric-oxide synthase biosynthetic process; ISS:BHF-UCL.::GO:0010572; P:positive regulation of platelet activation; ISS:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0042535; P:positive regulation of tumor necrosis factor biosynthetic process; IDA:UniProtKB.::GO:0032760; P:positive regulation of tumor necrosis factor production; ISS:BHF-UCL.::GO:0042088; P:T-helper 1 type immune response; NAS:UniProtKB.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome. | 143 | O93233 | 331 | PLIB_GLOBS Phospholipase A2 inhibitor subunit... | 238 | 0.006 | 44.7 | 28 | 43 | | | | | | | | | | | GO:0019834; F:phospholipase A2 inhibitor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 144 | Q4R6F0 | 863 | LRRD1_MACFA Leucine-rich repeat and death dom... | 105 | 0.006 | 45.4 | 38 | 50 | | | | | | | | | | | | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 145 | O94898 | 1065 | LRIG2_HUMAN Leucine-rich repeats and immunogl... | 376 | 0.006 | 45.4 | 24 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 146 | A1A4H9 | 521 | LRRT1_BOVIN Leucine-rich repeat transmembrane... | 224 | 0.006 | 45.1 | 26 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 147 | Q9V780 | 849 | LAP1_DROME Protein lap1 OS=Drosophila melanog... | 372 | 0.92 | 38.1 | 23 | 42 | GO:0005912; C:adherens junction; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0007163; P:establishment or maintenance of cell polarity; ISS:UniProtKB.::GO:0015031; P:protein transport; ISS:UniProtKB. | 148 | Q1RMS4 | 628 | LRFN3_BOVIN Leucine-rich repeat and fibronect... | 204 | 0.007 | 45.1 | 29 | 48 | GO:0030424; C:axon; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 149 | Q8SPE8 | 837 | TLR4_GORGO Toll-like receptor 4 OS=Gorilla go... | 187 | 0.007 | 45.1 | 29 | 47 | GO:0005622; C:intracellular; IEA:InterPro.::GO:0046696; C:lipopolysaccharide receptor complex; ISS:UniProtKB. | | | | | | | | | | GO:0001875; F:lipopolysaccharide receptor activity; ISS:UniProtKB.::GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro. | | | | | | | | | | GO:0032497; P:detection of lipopolysaccharide; ISS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0042116; P:macrophage activation; ISS:UniProtKB. | 150 | Q8R2R5 | 259 | LRC61_MOUSE Leucine-rich repeat-containing pr... | 112 | 0.048 | 41.6 | 33 | 47 | | | | | | | | | | | | | | | | | | | | | | 151 | A2ARI4 | 951 | LGR4_MOUSE Leucine-rich repeat-containing G-p... | 357 | 0.008 | 45.1 | 29 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016500; F:protein-hormone receptor activity; IEA:InterPro. | | | | | | | | | | GO:0061290; P:canonical Wnt receptor signaling pathway involved in metanephric kidney development; IMP:UniProtKB.::GO:0072202; P:cell differentiation involved in metanephros development; IMP:UniProtKB.::GO:0050673; P:epithelial cell proliferation; IMP:MGI.::GO:0030539; P:male genitalia development; IMP:MGI.::GO:0072224; P:metanephric glomerulus development; IMP:UniProtKB.::GO:0072282; P:metanephric nephron tubule morphogenesis; IMP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB. |