rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | P61586 | 193 | RHOA_HUMAN Transforming protein RhoA OS=Homo ... | 198 | 0.0000000000003 | 68.6 | 27 | 49 | GO:0043296; C:apical junction complex; IDA:UniProtKB.::GO:0005938; C:cell cortex; IDA:UniProtKB.::GO:0032154; C:cleavage furrow; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:UniProtKB.::GO:0017022; F:myosin binding; IPI:UniProtKB. | | | | | | | | | | GO:0043297; P:apical junction assembly; IMP:UniProtKB.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0050771; P:negative regulation of axonogenesis; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0043931; P:ossification involved in bone maturation; ISS:BHF-UCL.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0050772; P:positive regulation of axonogenesis; TAS:Reactome.::GO:0071777; P:positive regulation of cell cycle cytokinesis; IMP:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IEP:UniProtKB.::GO:0045666; P:positive regulation of neuron differentiation; IMP:MGI.::GO:0042346; P:positive regulation of NF-kappaB import into nucleus; NAS:UniProtKB.::GO:0051496; P:positive regulation of stress fiber assembly; IDA:MGI.::GO:0030334; P:regulation of cell migration; IMP:UniProtKB.::GO:0033688; P:regulation of osteoblast proliferation; ISS:BHF-UCL.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007266; P:Rho protein signal transduction; TAS:UniProtKB.::GO:0090307; P:spindle assembly involved in mitosis; IMP:BHF-UCL.::GO:0061383; P:trabecula morphogenesis; ISS:BHF-UCL. | 32 | P61585 | 193 | RHOA_BOVIN Transforming protein RhoA OS=Bos t... | 198 | 0.0000000000003 | 68.6 | 27 | 49 | GO:0043296; C:apical junction complex; ISS:UniProtKB.::GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0043297; P:apical junction assembly; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 33 | O13928 | 205 | RHO3_SCHPO GTP-binding protein rho3 OS=Schizo... | 198 | 0.0000000000004 | 68.2 | 28 | 49 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IMP:PomBase.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007163; P:establishment or maintenance of cell polarity; IMP:PomBase.::GO:0000226; P:microtubule cytoskeleton organization; IMP:PomBase.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0010590; P:regulation of cytokinetic cell separation; IMP:PomBase.::GO:0017157; P:regulation of exocytosis; TAS:PomBase.::GO:0007264; P:small GTPase mediated signal transduction; IC:PomBase. | 34 | P61589 | 193 | RHOA_RAT Transforming protein RhoA OS=Rattus ... | 198 | 0.0000000000005 | 67.8 | 26 | 49 | GO:0043296; C:apical junction complex; ISS:UniProtKB.::GO:0030424; C:axon; IDA:RGD.::GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005525; F:GTP binding; TAS:RGD.::GO:0003924; F:GTPase activity; NAS:RGD.::GO:0019904; F:protein domain specific binding; IPI:RGD. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; TAS:RGD.::GO:0043297; P:apical junction assembly; ISS:UniProtKB.::GO:0051927; P:negative regulation of calcium ion transport via voltage-gated calcium channel activity; IMP:RGD.::GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB cascade; IMP:RGD.::GO:0045665; P:negative regulation of neuron differentiation; IMP:RGD.::GO:0048812; P:neuron projection morphogenesis; IEP:RGD.::GO:0030838; P:positive regulation of actin filament polymerization; IMP:RGD.::GO:0045785; P:positive regulation of cell adhesion; IEP:RGD.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; IMP:RGD.::GO:0030335; P:positive regulation of cell migration; IEP:RGD.::GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:RGD.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0043525; P:positive regulation of neuron apoptotic process; IMP:RGD.::GO:0045727; P:positive regulation of translation; IEP:RGD.::GO:0045907; P:positive regulation of vasoconstriction; IEP:RGD.::GO:0050773; P:regulation of dendrite development; IMP:RGD.::GO:0043200; P:response to amino acid stimulus; IEP:RGD.::GO:0042493; P:response to drug; IDA:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0009612; P:response to mechanical stimulus; IEP:RGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0031098; P:stress-activated protein kinase signaling cascade; IMP:RGD. | 35 | Q9QUI0 | 193 | RHOA_MOUSE Transforming protein RhoA OS=Mus m... | 198 | 0.0000000000005 | 67.8 | 26 | 49 | GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:MGI.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0032587; C:ruffle membrane; IDA:MGI. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:MGI. | | | | | | | | | | GO:0030521; P:androgen receptor signaling pathway; IDA:MGI.::GO:0043297; P:apical junction assembly; IDA:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000902; P:cell morphogenesis; IGI:MGI.::GO:0007160; P:cell-matrix adhesion; IDA:MGI.::GO:0007229; P:integrin-mediated signaling pathway; TAS:MGI.::GO:0033144; P:negative regulation of intracellular steroid hormone receptor signaling pathway; IDA:MGI.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:MGI.::GO:0043931; P:ossification involved in bone maturation; IMP:BHF-UCL.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.::GO:0033688; P:regulation of osteoblast proliferation; IMP:BHF-UCL.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0007266; P:Rho protein signal transduction; TAS:MGI.::GO:0007519; P:skeletal muscle tissue development; IDA:MGI.::GO:0043149; P:stress fiber assembly; IDA:MGI.::GO:0061383; P:trabecula morphogenesis; IMP:BHF-UCL. | 36 | O42825 | 198 | RHO1_CANAL GTP-binding protein RHO1 OS=Candid... | 192 | 0.0000000000005 | 67.8 | 30 | 47 | GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IDA:CGD. | | | | | | | | | | GO:0005525; F:GTP binding; IDA:CGD.::GO:0003924; F:GTPase activity; ISS:CGD.::GO:0004871; F:signal transducer activity; IDA:CGD. | | | | | | | | | | GO:0006075; P:(1->3)-beta-D-glucan biosynthetic process; IMP:CGD.::GO:0035690; P:cellular response to drug; IMP:CGD.::GO:0007266; P:Rho protein signal transduction; IDA:CGD. | 37 | C4YDI6 | 191 | CDC42_CANAW Cell division control protein 42 ... | 193 | 0.0000000000005 | 67.8 | 27 | 46 | GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 38 | P0CY33 | 191 | CDC42_CANAL Cell division control protein 42 ... | 193 | 0.0000000000005 | 67.8 | 27 | 46 | GO:0030428; C:cell septum; NAS:CGD.::GO:0005935; C:cellular bud neck; IDA:CGD.::GO:0005934; C:cellular bud tip; IDA:CGD.::GO:0031562; C:hyphal tip polarisome; IDA:CGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0031521; C:spitzenkorper; IDA:CGD. | | | | | | | | | | GO:0005525; F:GTP binding; IDA:CGD. | | | | | | | | | | GO:0007114; P:cell budding; IMP:CGD.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000920; P:cytokinetic cell separation; IMP:CGD.::GO:0030010; P:establishment of cell polarity; IMP:CGD.::GO:0030448; P:hyphal growth; IMP:CGD.::GO:0009405; P:pathogenesis; IMP:CGD.::GO:0001558; P:regulation of cell growth; IMP:CGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 39 | Q01112 | 192 | CDC42_SCHPO Cell division control protein 42 ... | 203 | 0.0000000000005 | 67.8 | 27 | 47 | GO:0071521; C:Cdc42 GTPase complex; NAS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0009898; C:internal side of plasma membrane; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:PomBase.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0032488; P:Cdc42 protein signal transduction; IC:PomBase.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IMP:PomBase.::GO:0032955; P:regulation of barrier septum assembly; IMP:PomBase.::GO:0032951; P:regulation of beta-glucan biosynthetic process; IGI:PomBase.::GO:0031137; P:regulation of conjugation with cellular fusion; IMP:PomBase.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; IMP:PomBase. | 40 | P24406 | 193 | RHOA_CANFA Transforming protein RhoA OS=Canis... | 198 | 0.0000000000008 | 67.4 | 27 | 48 | GO:0043296; C:apical junction complex; ISS:UniProtKB.::GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0043297; P:apical junction assembly; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 41 | P01122 | 192 | RHO_APLCA Ras-like GTP-binding protein RHO OS... | 198 | 0.000000000001 | 67 | 28 | 49 | GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 42 | P53879 | 331 | RHO5_YEAST GTP-binding protein RHO5 OS=Saccha... | 143 | 0.000000000001 | 68.6 | 35 | 50 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005624; C:membrane fraction; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:SGD. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 43 | P06780 | 209 | RHO1_YEAST GTP-binding protein RHO1 OS=Saccha... | 198 | 0.000000000001 | 66.6 | 29 | 46 | GO:0000148; C:1,3-beta-D-glucan synthase complex; IDA:SGD.::GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:SGD.::GO:0000131; C:incipient cellular bud site; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0005741; C:mitochondrial outer membrane; IDA:SGD.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004871; F:signal transducer activity; TAS:SGD. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; IPI:SGD.::GO:0007117; P:budding cell bud growth; IMP:SGD.::GO:0045807; P:positive regulation of endocytosis; IMP:SGD.::GO:0090037; P:positive regulation of protein kinase C signaling cascade; IMP:SGD.::GO:0008361; P:regulation of cell size; IMP:SGD.::GO:0060178; P:regulation of exocyst localization; IMP:SGD.::GO:0070610; P:regulation of fungal-type cell wall (1->3)-alpha-glucan biosynthetic process; IMP:SGD.::GO:0060237; P:regulation of fungal-type cell wall organization; IMP:SGD.::GO:0032889; P:regulation of vacuole fusion, non-autophagic; IMP:SGD.::GO:0007264; P:small GTPase mediated signal transduction; IDA:SGD. | 44 | Q03206 | 191 | RAC1_CAEEL Ras-related protein ced-10 OS=Caen... | 202 | 0.000000000002 | 66.2 | 27 | 47 | GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0031410; C:cytoplasmic vesicle; IDA:WormBase.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005626; C:insoluble fraction; IDA:WormBase.::GO:0016021; C:integral to membrane; IDA:UniProtKB.::GO:0009898; C:internal side of plasma membrane; IDA:WormBase.::GO:0005625; C:soluble fraction; IDA:WormBase. | | | | | | | | | | GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0048846; P:axon extension involved in axon guidance; IGI:WormBase.::GO:0031103; P:axon regeneration; IMP:WormBase.::GO:0010171; P:body morphogenesis; IGI:WormBase.::GO:0033563; P:dorsal/ventral axon guidance; IGI:WormBase.::GO:0043652; P:engulfment of apoptotic cell; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040039; P:inductive cell migration; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0008045; P:motor axon guidance; IGI:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0001764; P:neuron migration; IGI:WormBase.::GO:0040026; P:positive regulation of vulval development; IMP:WormBase.::GO:0030334; P:regulation of cell migration; IDA:UniProtKB.::GO:0050764; P:regulation of phagocytosis; IMP:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IDA:UniProtKB. | 45 | Q6RUV5 | 192 | RAC1_RAT Ras-related C3 botulinum toxin subst... | 186 | 0.000000000002 | 66.2 | 28 | 46 | GO:0000139; C:Golgi membrane; IDA:RGD.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IDA:RGD.::GO:0003924; F:GTPase activity; IDA:RGD.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL.::GO:0017137; F:Rab GTPase binding; IPI:RGD. | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:RGD.::GO:0045453; P:bone resorption; IDA:RGD.::GO:0008283; P:cell proliferation; IMP:RGD.::GO:0002551; P:mast cell chemotaxis; IMP:RGD.::GO:0045740; P:positive regulation of DNA replication; IMP:RGD.::GO:0016601; P:Rac protein signal transduction; TAS:RGD.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB. | 46 | P63001 | 192 | RAC1_MOUSE Ras-related C3 botulinum toxin sub... | 186 | 0.000000000002 | 66.2 | 28 | 46 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0019897; C:extrinsic to plasma membrane; IDA:MGI.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0001891; C:phagocytic cup; IDA:UniProtKB.::GO:0032587; C:ruffle membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005525; F:GTP binding; IDA:MGI.::GO:0030742; F:GTP-dependent protein binding; IPI:UniProtKB.::GO:0003924; F:GTPase activity; IDA:MGI. | | | | | | | | | | GO:0048532; P:anatomical structure arrangement; IMP:MGI.::GO:0002093; P:auditory receptor cell morphogenesis; IMP:MGI.::GO:0007411; P:axon guidance; IMP:MGI.::GO:0045216; P:cell-cell junction organization; IMP:MGI.::GO:0021799; P:cerebral cortex radially oriented cell migration; IMP:MGI.::GO:0090103; P:cochlea morphogenesis; IMP:MGI.::GO:0007010; P:cytoskeleton organization; IDA:MGI.::GO:0048813; P:dendrite morphogenesis; IGI:MGI.::GO:0071542; P:dopaminergic neuron differentiation; IGI:MGI.::GO:0021831; P:embryonic olfactory bulb interneuron precursor migration; IMP:MGI.::GO:0043652; P:engulfment of apoptotic cell; IDA:BHF-UCL.::GO:0003382; P:epithelial cell morphogenesis; IMP:MGI.::GO:0006972; P:hyperosmotic response; IDA:MGI.::GO:0030032; P:lamellipodium assembly; IDA:MGI.::GO:0030838; P:positive regulation of actin filament polymerization; IDA:MGI.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IMP:MGI.::GO:0030334; P:regulation of cell migration; IMP:MGI.::GO:0097178; P:ruffle assembly; IMP:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IDA:MGI.::GO:0034446; P:substrate adhesion-dependent cell spreading; IDA:MGI.::GO:0060071; P:Wnt receptor signaling pathway, planar cell polarity pathway; IGI:MGI. | 47 | P63000 | 192 | RAC1_HUMAN Ras-related C3 botulinum toxin sub... | 186 | 0.000000000002 | 66.2 | 28 | 46 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; TAS:UniProtKB.::GO:0031996; F:thioesterase binding; IPI:UniProtKB. | | | | | | | | | | GO:0030041; P:actin filament polymerization; TAS:UniProtKB.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0048870; P:cell motility; IDA:UniProtKB.::GO:0007160; P:cell-matrix adhesion; NAS:BHF-UCL.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0006954; P:inflammatory response; TAS:ProtInc.::GO:0030032; P:lamellipodium assembly; IMP:UniProtKB.::GO:0051668; P:localization within membrane; IMP:BHF-UCL.::GO:0032707; P:negative regulation of interleukin-23 production; IDA:BHF-UCL.::GO:0048261; P:negative regulation of receptor-mediated endocytosis; TAS:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0010592; P:positive regulation of lamellipodium assembly; IDA:MGI.::GO:0035025; P:positive regulation of Rho protein signal transduction; TAS:UniProtKB.::GO:0030334; P:regulation of cell migration; IMP:UniProtKB.::GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.::GO:0010310; P:regulation of hydrogen peroxide metabolic process; TAS:BHF-UCL.::GO:0060263; P:regulation of respiratory burst; IDA:BHF-UCL.::GO:0031529; P:ruffle organization; TAS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome. | 48 | P62999 | 192 | RAC1_CANFA Ras-related C3 botulinum toxin sub... | 186 | 0.000000000002 | 66.2 | 28 | 46 | GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; ISS:UniProtKB. | | | | | | | | | | GO:0048870; P:cell motility; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 49 | P62998 | 192 | RAC1_BOVIN Ras-related C3 botulinum toxin sub... | 186 | 0.000000000002 | 66.2 | 28 | 46 | GO:0042470; C:melanosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; ISS:UniProtKB. | | | | | | | | | | GO:0030334; P:regulation of cell migration; ISS:UniProtKB. | 50 | P15153 | 192 | RAC2_HUMAN Ras-related C3 botulinum toxin sub... | 186 | 0.000000000002 | 66.2 | 28 | 46 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0010310; P:regulation of hydrogen peroxide metabolic process; TAS:BHF-UCL.::GO:0060263; P:regulation of respiratory burst; IDA:BHF-UCL.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 51 | A5D7J5 | 255 | RHOU_BOVIN Rho-related GTP-binding protein Rh... | 194 | 0.000000000002 | 66.6 | 27 | 48 | GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0002102; C:podosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008360; P:regulation of cell shape; ISS:UniProtKB. | 52 | Q9TU25 | 192 | RAC2_BOVIN Ras-related C3 botulinum toxin sub... | 186 | 0.000000000002 | 65.9 | 28 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 53 | P40793 | 191 | CDC42_DROME Cdc42 homolog OS=Drosophila melan... | 186 | 0.000000000006 | 64.7 | 25 | 47 | GO:0005912; C:adherens junction; IDA:UniProtKB.::GO:0030424; C:axon; IDA:FlyBase.::GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0030426; C:growth cone; IDA:FlyBase.::GO:0005634; C:nucleus; IDA:FlyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0016028; C:rhabdomere; IMP:FlyBase. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; NAS:FlyBase.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0030041; P:actin filament polymerization; IMP:FlyBase.::GO:0060446; P:branching involved in open tracheal system development; IMP:FlyBase.::GO:0030031; P:cell projection assembly; IMP:FlyBase.::GO:0007349; P:cellularization; TAS:FlyBase.::GO:0030866; P:cortical actin cytoskeleton organization; IMP:FlyBase.::GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.::GO:0046843; P:dorsal appendage formation; IMP:FlyBase.::GO:0045200; P:establishment of neuroblast polarity; IMP:FlyBase.::GO:0035099; P:hemocyte migration; IMP:FlyBase.::GO:0035318; P:imaginal disc-derived wing hair outgrowth; IMP:FlyBase.::GO:0007254; P:JNK cascade; TAS:FlyBase.::GO:0030011; P:maintenance of cell polarity; IMP:FlyBase.::GO:0045185; P:maintenance of protein location; IMP:UniProtKB.::GO:0008045; P:motor axon guidance; IMP:FlyBase.::GO:0007274; P:neuromuscular synaptic transmission; IGI:FlyBase.::GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.::GO:0045860; P:positive regulation of protein kinase activity; IMP:UniProtKB.::GO:0030833; P:regulation of actin filament polymerization; IDA:FlyBase.::GO:0050770; P:regulation of axonogenesis; IGI:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0008582; P:regulation of synaptic growth at neuromuscular junction; IDA:FlyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0007396; P:suture of dorsal opening; TAS:FlyBase.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:FlyBase.::GO:0042060; P:wound healing; IMP:FlyBase. | 54 | P60764 | 192 | RAC3_MOUSE Ras-related C3 botulinum toxin sub... | 186 | 0.000000000006 | 64.7 | 28 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0012505; C:endomembrane system; ISS:UniProtKB.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0030031; P:cell projection assembly; ISS:UniProtKB.::GO:0050885; P:neuromuscular process controlling balance; IMP:MGI.::GO:0031175; P:neuron projection development; IDA:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 55 | P60763 | 192 | RAC3_HUMAN Ras-related C3 botulinum toxin sub... | 186 | 0.000000000006 | 64.7 | 28 | 45 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0012505; C:endomembrane system; IDA:UniProtKB.::GO:0031941; C:filamentous actin; IDA:MGI.::GO:0030426; C:growth cone; IDA:MGI.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.::GO:0030031; P:cell projection assembly; IDA:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 56 | Q05144 | 192 | RAC2_MOUSE Ras-related C3 botulinum toxin sub... | 186 | 0.000000000006 | 64.7 | 28 | 46 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0005635; C:nuclear envelope; IDA:MGI. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:MGI. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IDA:MGI.::GO:0030031; P:cell projection assembly; IDA:MGI.::GO:0006935; P:chemotaxis; IDA:MGI.::GO:0008284; P:positive regulation of cell proliferation; IMP:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 57 | Q9HE04 | 200 | RHO5_SCHPO GTP-binding protein rho5 OS=Schizo... | 188 | 0.000000000006 | 64.7 | 30 | 46 | GO:0032153; C:cell division site; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0031520; C:plasma membrane of cell tip; IC:PomBase. | | | | | | | | | | GO:0005525; F:GTP binding; IC:PomBase.::GO:0003924; F:GTPase activity; TAS:PomBase. | | | | | | | | | | GO:0030100; P:regulation of endocytosis; ISS:PomBase.::GO:0032995; P:regulation of fungal-type cell wall biogenesis; IMP:PomBase.::GO:0007264; P:small GTPase mediated signal transduction; IC:PomBase. | 58 | Q17031 | 191 | CDC42_ANOGA Cdc42 homolog OS=Anopheles gambia... | 186 | 0.000000000007 | 64.3 | 25 | 47 | GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 59 | Q54YY4 | 219 | RACN_DICDI Rho-related protein racN OS=Dictyo... | 179 | 0.000000000009 | 64.7 | 28 | 48 | GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 60 | P84096 | 191 | RHOG_MOUSE Rho-related GTP-binding protein Rh... | 202 | 0.000000000009 | 64.3 | 25 | 47 | GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0032863; P:activation of Rac GTPase activity; ISS:UniProtKB.::GO:0060326; P:cell chemotaxis; ISS:UniProtKB.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; ISS:UniProtKB. | 61 | P84095 | 191 | RHOG_HUMAN Rho-related GTP-binding protein Rh... | 202 | 0.000000000009 | 64.3 | 25 | 47 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:MGI.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IDA:MGI.::GO:0032863; P:activation of Rac GTPase activity; IMP:UniProtKB.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0060326; P:cell chemotaxis; IMP:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:MGI.::GO:0016601; P:Rac protein signal transduction; IDA:MGI.::GO:0007266; P:Rho protein signal transduction; IDA:MGI. |