| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | A5PJJ7 | 316 | S16C6_BOVIN Short-chain dehydrogenase/reducta... | 156 | 0.001 | 43.5 | 29 | 44 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 32 | Q41249 | 398 | PORA_CUCSA Protochlorophyllide reductase, chl... | 108 | 0.002 | 43.5 | 31 | 47 | GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016630; F:protochlorophyllide reductase activity; IEA:EC. | | | | | | | | | | GO:0015995; P:chlorophyll biosynthetic process; IEA:UniProtKB-KW.::GO:0015979; P:photosynthesis; IEA:UniProtKB-KW. | 33 | P48758 | 277 | CBR1_MOUSE Carbonyl reductase [NADPH] 1 OS=Mu... | 292 | 0.002 | 43.1 | 23 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC. | | | | | | | | | | GO:0017144; P:drug metabolic process; ISS:UniProtKB.::GO:0042373; P:vitamin K metabolic process; ISS:UniProtKB. | 34 | P47727 | 277 | CBR1_RAT Carbonyl reductase [NADPH] 1 OS=Ratt... | 290 | 0.002 | 43.1 | 23 | 42 | GO:0005829; C:cytosol; TAS:RGD.::GO:0005792; C:microsome; IDA:RGD.::GO:0005902; C:microvillus; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:RGD. | | | | | | | | | | GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC. | | | | | | | | | | GO:0017144; P:drug metabolic process; ISS:UniProtKB.::GO:0001542; P:ovulation from ovarian follicle; IEP:RGD.::GO:0018205; P:peptidyl-lysine modification; NAS:RGD.::GO:0042376; P:phylloquinone catabolic process; IDA:RGD.::GO:0034698; P:response to gonadotropin stimulus; IEP:RGD.::GO:0033574; P:response to testosterone stimulus; IEP:RGD. | 35 | P51975 | 292 | DHI1_SHEEP Corticosteroid 11-beta-dehydrogena... | 146 | 0.003 | 42.7 | 29 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 36 | Q8K354 | 277 | CBR3_MOUSE Carbonyl reductase [NADPH] 3 OS=Mu... | 249 | 0.004 | 42 | 24 | 43 | | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IEA:EC. | | | | | | | | | | | 37 | A0PJE2 | 317 | DHR12_HUMAN Dehydrogenase/reductase SDR famil... | 165 | 0.005 | 42 | 24 | 40 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 38 | Q64591 | 335 | DECR_RAT 2,4-dienoyl-CoA reductase, mitochond... | 39 | 0.005 | 42 | 49 | 67 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008670; F:2,4-dienoyl-CoA reductase (NADPH) activity; TAS:RGD. | | | | | | | | | | | 39 | Q6Q7D2 | 287 | DHI1L_MACFA Hydroxysteroid 11-beta-dehydrogen... | 147 | 0.006 | 41.6 | 33 | 46 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 40 | Q7Z5J1 | 315 | DHI1L_HUMAN Hydroxysteroid 11-beta-dehydrogen... | 147 | 0.008 | 41.2 | 32 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 41 | Q13268 | 258 | DHRS2_HUMAN Dehydrogenase/reductase SDR famil... | 262 | 0.01 | 40.8 | 27 | 40 | GO:0005739; C:mitochondrion; IDA:UniProtKB.::GO:0005635; C:nuclear envelope; IDA:UniProtKB. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008207; P:C21-steroid hormone metabolic process; NAS:UniProtKB.::GO:0034599; P:cellular response to oxidative stress; IDA:UniProtKB.::GO:0043011; P:myeloid dendritic cell differentiation; IEP:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; NAS:UniProtKB.::GO:0009636; P:response to toxin; IDA:UniProtKB. | 42 | Q9QYF1 | 316 | RDH11_MOUSE Retinol dehydrogenase 11 OS=Mus m... | 292 | 0.012 | 40.8 | 27 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0001917; C:photoreceptor inner segment; IDA:MGI. | | | | | | | | | | GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0016062; P:adaptation of rhodopsin mediated signaling; IMP:MGI.::GO:0042572; P:retinol metabolic process; ISS:UniProtKB. | 43 | O75828 | 277 | CBR3_HUMAN Carbonyl reductase [NADPH] 3 OS=Ho... | 241 | 0.015 | 40.4 | 25 | 41 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:UniProtKB.::GO:0070402; F:NADPH binding; IDA:UniProtKB. | | | | | | | | | | | 44 | Q9SDT1 | 398 | POR_DAUCA Protochlorophyllide reductase, chlo... | 96 | 0.019 | 40.4 | 30 | 48 | GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016630; F:protochlorophyllide reductase activity; IEA:EC. | | | | | | | | | | GO:0015995; P:chlorophyll biosynthetic process; IEA:UniProtKB-KW.::GO:0015979; P:photosynthesis; IEA:UniProtKB-KW. | 45 | P21218 | 401 | PORB_ARATH Protochlorophyllide reductase B, c... | 337 | 0.023 | 40 | 26 | 41 | GO:0009707; C:chloroplast outer membrane; IEA:UniProtKB-SubCell.::GO:0009535; C:chloroplast thylakoid membrane; IDA:TAIR. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016630; F:protochlorophyllide reductase activity; IEA:EC. | | | | | | | | | | GO:0015995; P:chlorophyll biosynthetic process; IEA:UniProtKB-KW.::GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.::GO:0009723; P:response to ethylene stimulus; IEP:TAIR. | 46 | O48741 | 401 | PORC_ARATH Protochlorophyllide reductase C, c... | 306 | 0.024 | 40 | 25 | 39 | GO:0009941; C:chloroplast envelope; IDA:TAIR.::GO:0009535; C:chloroplast thylakoid membrane; IDA:TAIR. | | | | | | | | | | GO:0003959; F:NADPH dehydrogenase activity; IDA:TAIR.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016630; F:protochlorophyllide reductase activity; IEA:EC. | | | | | | | | | | GO:0015995; P:chlorophyll biosynthetic process; IEA:UniProtKB-KW.::GO:0015979; P:photosynthesis; IEA:UniProtKB-KW. | 47 | Q7M3I4 | 292 | DHI1_RABIT Corticosteroid 11-beta-dehydrogena... | 145 | 0.034 | 39.3 | 28 | 43 | GO:0005789; C:endoplasmic reticulum membrane; NAS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:UniProtKB. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008211; P:glucocorticoid metabolic process; NAS:UniProtKB.] | 48 | P43713 | 242 | FABG_HAEIN 3-oxoacyl-[acyl-carrier-protein] r... | 143 | 0.046 | 38.5 | 24 | 41 | | | | | | | | | | | GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; ISS:UniProtKB. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.] | 49 | O31680 | 248 | YKVO_BACSU Uncharacterized oxidoreductase ykv... | 142 | 0.047 | 38.5 | 32 | 46 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 50 | P28845 | 292 | DHI1_HUMAN Corticosteroid 11-beta-dehydrogena... | 148 | 0.072 | 38.1 | 27 | 43 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; TAS:Reactome.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006704; P:glucocorticoid biosynthetic process; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.] | 51 | Q9KQH7 | 244 | FABG_VIBCH 3-oxoacyl-[acyl-carrier-protein] r... | 250 | 0.078 | 37.7 | 22 | 41 | | | | | | | | | | | GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; ISS:UniProtKB. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.] | 52 | P70720 | 242 | FABG_AGGAC 3-oxoacyl-[acyl-carrier-protein] r... | 165 | 0.11 | 37.4 | 25 | 48 | | | | | | | | | | | GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.] | 53 | Q6PUF3 | 287 | DHI1L_DANRE Hydroxysteroid 11-beta-dehydrogen... | 149 | 0.12 | 37.4 | 31 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016229; F:steroid dehydrogenase activity; ISS:ZFIN. | | | | | | | | | | | 54 | O02691 | 261 | HCD2_BOVIN 3-hydroxyacyl-CoA dehydrogenase ty... | 51 | 0.12 | 37.4 | 47 | 57 | | | | | | | | | | | GO:0047015; F:3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity; IEA:EC.::GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008033; P:tRNA processing; IEA:UniProtKB-KW. | 55 | Q39617 | 397 | POR_CHLRE Protochlorophyllide reductase, chlo... | 103 | 0.13 | 37.7 | 29 | 44 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016630; F:protochlorophyllide reductase activity; IEA:EC. | | | | | | | | | | GO:0015995; P:chlorophyll biosynthetic process; IEA:UniProtKB-KW.::GO:0015979; P:photosynthesis; IEA:UniProtKB-KW. | 56 | A4IGM4 | 286 | DHI1L_XENTR Hydroxysteroid 11-beta-dehydrogen... | 150 | 0.13 | 37.4 | 27 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 57 | Q9P7B4 | 259 | YI13_SCHPO Uncharacterized oxidoreductase C52... | 135 | 0.14 | 37.4 | 23 | 45 | GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 58 | Q29608 | 291 | DHI1_SAISC Corticosteroid 11-beta-dehydrogena... | 144 | 0.15 | 37.4 | 26 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 59 | Q7XKF3 | 387 | PORA_ORYSJ Protochlorophyllide reductase A, c... | 341 | 0.17 | 37.4 | 26 | 40 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016630; F:protochlorophyllide reductase activity; IEA:EC. | | | | | | | | | | GO:0015995; P:chlorophyll biosynthetic process; IEA:UniProtKB-KW.::GO:0015979; P:photosynthesis; IEA:UniProtKB-KW. | 60 | P23238 | 241 | PHBB_ZOORA Acetoacetyl-CoA reductase OS=Zoogl... | 262 | 0.21 | 36.6 | 22 | 37 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018454; F:acetoacetyl-CoA reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0042619; P:poly-hydroxybutyrate biosynthetic process; IEA:UniProtKB-KW. | 61 | O14351 | 247 | YB45_SCHPO Uncharacterized oxidoreductase C30... | 246 | 0.21 | 36.6 | 25 | 41 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004757; F:sepiapterin reductase activity; ISS:PomBase. | | | | | | | | | | GO:0006729; P:tetrahydrobiopterin biosynthetic process; ISS:PomBase. |
