rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | P60982 | 165 | DEST_PIG Destrin OS=Sus scrofa (Pig). GN=DSTN... | 149 | 6e-18 | 80.5 | 36 | 51 | GO:0030864; C:cortical actin cytoskeleton; ISS:AgBase. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006928; P:cellular component movement; ISS:AgBase.::GO:0000910; P:cytokinesis; ISS:AgBase.::GO:0030836; P:positive regulation of actin filament depolymerization; ISS:AgBase. | 62 | P60981 | 165 | DEST_HUMAN Destrin OS=Homo sapiens (Human). G... | 149 | 6e-18 | 80.5 | 36 | 51 | | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051014; P:actin filament severing; TAS:ProtInc.::GO:0008154; P:actin polymerization or depolymerization; TAS:ProtInc. | 63 | Q5E9D5 | 165 | DEST_BOVIN Destrin OS=Bos taurus (Bovine). GN... | 149 | 6e-18 | 80.5 | 36 | 51 | GO:0030864; C:cortical actin cytoskeleton; ISS:AgBase. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006928; P:cellular component movement; ISS:AgBase.::GO:0000910; P:cytokinesis; ISS:AgBase.::GO:0030836; P:positive regulation of actin filament depolymerization; ISS:AgBase. | 64 | Q0DLA3 | 139 | ADF7_ORYSJ Actin-depolymerizing factor 7 OS=O... | 141 | 8e-18 | 79.7 | 37 | 59 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 65 | Q6NX11 | 168 | COF1_XENTR Cofilin-1 OS=Xenopus tropicalis (W... | 149 | 1e-17 | 79.7 | 34 | 53 | GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051015; F:actin filament binding; ISS:UniProtKB. | | | | | | | | | | GO:0030042; P:actin filament depolymerization; ISS:UniProtKB.::GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB. | 66 | P45594 | 148 | CADF_DROME Cofilin/actin-depolymerizing facto... | 144 | 2e-17 | 78.6 | 35 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IMP:FlyBase. | | | | | | | | | | GO:0030041; P:actin filament polymerization; IMP:FlyBase.::GO:0007409; P:axonogenesis; IMP:FlyBase.::GO:0007298; P:border follicle cell migration; IMP:FlyBase.::GO:0000915; P:cytokinesis, actomyosin contractile ring assembly; TAS:FlyBase.::GO:0001737; P:establishment of imaginal disc-derived wing hair orientation; IMP:FlyBase.::GO:0042067; P:establishment of ommatidial planar polarity; IMP:FlyBase.::GO:0008585; P:female gonad development; IMP:FlyBase.::GO:0036011; P:imaginal disc-derived leg segmentation; IMP:FlyBase.::GO:0016319; P:mushroom body development; IMP:FlyBase.::GO:0010591; P:regulation of lamellipodium assembly; IMP:FlyBase.::GO:0042052; P:rhabdomere development; IMP:FlyBase. | 67 | P18359 | 165 | DEST_CHICK Destrin OS=Gallus gallus (Chicken)... | 149 | 4e-17 | 78.2 | 35 | 51 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 68 | P30174 | 126 | ADF_BRANA Actin-depolymerizing factor OS=Bras... | 70 | 8e-17 | 76.6 | 50 | 71 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 69 | Q8SAG3 | 143 | ADF_VITVI Actin-depolymerizing factor OS=Viti... | 138 | 1e-16 | 76.3 | 36 | 57 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 70 | P86293 | 143 | CADF2_PLAFX Cofilin/actin-depolymerizing fact... | 138 | 3e-16 | 75.5 | 33 | 58 | GO:0015629; C:actin cytoskeleton; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003785; F:actin monomer binding; ISS:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0060327; P:cytoplasmic actin-based contraction involved in cell motility; ISS:UniProtKB. | 71 | Q8ID92 | 143 | CADF2_PLAF7 Cofilin/actin-depolymerizing fact... | 138 | 3e-16 | 75.5 | 33 | 58 | GO:0015629; C:actin cytoskeleton; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003785; F:actin monomer binding; ISS:UniProtKB. | | | | | | | | | | GO:0008154; P:actin polymerization or depolymerization; ISS:GeneDB_Pfalciparum.::GO:0060327; P:cytoplasmic actin-based contraction involved in cell motility; ISS:UniProtKB. | 72 | Q9LZT3 | 133 | ADF11_ARATH Putative actin-depolymerizing fac... | 145 | 3e-16 | 75.1 | 33 | 54 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 73 | Q337A5 | 151 | ADF10_ORYSJ Actin-depolymerizing factor 10 OS... | 144 | 0.000000000000003 | 72.8 | 33 | 53 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 74 | Q0D744 | 146 | ADF8_ORYSJ Putative actin-depolymerizing fact... | 124 | 0.00000000000008 | 68.9 | 32 | 52 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 75 | Q07750 | 212 | ADF1_CAEEL Actin-depolymerizing factor 1, iso... | 158 | 0.000000000005 | 64.3 | 35 | 53 | GO:0005865; C:striated muscle thin filament; IDA:WormBase. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:WormBase. | | | | | | | | | | GO:0030042; P:actin filament depolymerization; IDA:WormBase.::GO:0051014; P:actin filament severing; IDA:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0030838; P:positive regulation of actin filament polymerization; IDA:WormBase.::GO:0030240; P:skeletal muscle thin filament assembly; IMP:WormBase. | 76 | Q07749 | 152 | ADF2_CAEEL Actin-depolymerizing factor 2, iso... | 150 | 0.00000000005 | 60.8 | 32 | 50 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 77 | Q9VFM9 | 343 | TWF_DROME Twinfilin OS=Drosophila melanogaste... | 120 | 0.00000002 | 55.1 | 33 | 47 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IMP:UniProtKB. | | | | | | | | | | GO:0030042; P:actin filament depolymerization; IDA:FlyBase.::GO:0007298; P:border follicle cell migration; IMP:FlyBase.::GO:0008407; P:chaeta morphogenesis; IMP:FlyBase.::GO:0016319; P:mushroom body development; IMP:FlyBase.::GO:0007274; P:neuromuscular synaptic transmission; IMP:FlyBase.::GO:0030833; P:regulation of actin filament polymerization; IMP:UniProtKB.::GO:0010591; P:regulation of lamellipodium assembly; IMP:FlyBase.::GO:0048488; P:synaptic vesicle endocytosis; IMP:FlyBase. | 78 | Q7QG28 | 343 | TWF_ANOGA Twinfilin OS=Anopheles gambiae (Afr... | 138 | 0.00000007 | 53.9 | 28 | 49 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 79 | Q298X4 | 345 | TWF_DROPS Twinfilin OS=Drosophila pseudoobscu... | 140 | 0.0000001 | 52.8 | 31 | 45 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; ISS:UniProtKB. | | | | | | | | | | GO:0030833; P:regulation of actin filament polymerization; ISS:UniProtKB. | 80 | Q5RJR2 | 350 | TWF1_RAT Twinfilin-1 OS=Rattus norvegicus (Ra... | 124 | 0.0000002 | 52.8 | 28 | 50 | | | | | | | | | | | | | | | | | | | | | | 81 | Q91YR1 | 350 | TWF1_MOUSE Twinfilin-1 OS=Mus musculus (Mouse... | 124 | 0.0000002 | 52.4 | 28 | 50 | GO:0015629; C:actin cytoskeleton; IDA:UniProtKB.::GO:0005911; C:cell-cell junction; IDA:BHF-UCL.::GO:0030175; C:filopodium; IDA:BHF-UCL.::GO:0030016; C:myofibril; IDA:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL. | | | | | | | | | | GO:0003785; F:actin monomer binding; IDA:BHF-UCL.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:BHF-UCL.::GO:0004713; F:protein tyrosine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0051016; P:barbed-end actin filament capping; IDA:BHF-UCL.::GO:0042989; P:sequestering of actin monomers; IDA:BHF-UCL. | 82 | Q17A58 | 343 | TWF_AEDAE Twinfilin OS=Aedes aegypti (Yellowf... | 119 | 0.0000005 | 51.2 | 29 | 51 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 83 | Q5I082 | 350 | TWF1_XENTR Twinfilin-1 OS=Xenopus tropicalis ... | 153 | 0.0000008 | 50.4 | 27 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 84 | Q12792 | 350 | TWF1_HUMAN Twinfilin-1 OS=Homo sapiens (Human... | 124 | 0.000003 | 49.3 | 27 | 50 | GO:0015629; C:actin cytoskeleton; ISS:UniProtKB.::GO:0005911; C:cell-cell junction; ISS:BHF-UCL.::GO:0030175; C:filopodium; ISS:BHF-UCL.::GO:0030016; C:myofibril; ISS:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; ISS:BHF-UCL. | | | | | | | | | | GO:0003785; F:actin monomer binding; ISS:BHF-UCL.::GO:0005524; F:ATP binding; IDA:BHF-UCL.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; ISS:BHF-UCL. | | | | | | | | | | GO:0043538; P:regulation of actin phosphorylation; IDA:BHF-UCL.::GO:0042989; P:sequestering of actin monomers; ISS:BHF-UCL. | 85 | Q68F50 | 350 | TWF1_XENLA Twinfilin-1 OS=Xenopus laevis (Afr... | 153 | 0.000003 | 48.9 | 26 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 86 | Q556H5 | 138 | COF3_DICDI Cofilin-3 OS=Dictyostelium discoid... | 133 | 0.000003 | 47 | 24 | 49 | GO:0015629; C:actin cytoskeleton; ISS:dictyBase.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 87 | Q5R7N2 | 350 | TWF1_PONAB Twinfilin-1 OS=Pongo abelii (Sumat... | 101 | 0.000005 | 48.1 | 29 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 88 | Q56JV6 | 350 | TWF1_BOVIN Twinfilin-1 OS=Bos taurus (Bovine)... | 101 | 0.00001 | 47 | 28 | 50 | | | | | | | | | | | | | | | | | | | | | | 89 | Q5RFH1 | 341 | TWF2_PONAB Twinfilin-2 OS=Pongo abelii (Sumat... | 69 | 0.0002 | 43.1 | 32 | 55 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0032420; C:stereocilium; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030030; P:cell projection organization; IEA:UniProtKB-KW. | 90 | Q6IBS0 | 349 | TWF2_HUMAN Twinfilin-2 OS=Homo sapiens (Human... | 69 | 0.0003 | 43.1 | 32 | 55 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030175; C:filopodium; ISS:BHF-UCL.::GO:0030426; C:growth cone; IDA:BHF-UCL.::GO:0030027; C:lamellipodium; ISS:BHF-UCL.::GO:0030016; C:myofibril; ISS:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; ISS:BHF-UCL.::GO:0032420; C:stereocilium; ISS:BHF-UCL. | | | | | | | | | | GO:0003785; F:actin monomer binding; ISS:BHF-UCL.::GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; ISS:BHF-UCL.::GO:0005080; F:protein kinase C binding; IPI:BHF-UCL. | | | | | | | | | | GO:0051016; P:barbed-end actin filament capping; ISS:BHF-UCL.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0071363; P:cellular response to growth factor stimulus; IMP:BHF-UCL.::GO:0071300; P:cellular response to retinoic acid; IMP:BHF-UCL.::GO:0045773; P:positive regulation of axon extension; IMP:BHF-UCL.::GO:0010592; P:positive regulation of lamellipodium assembly; IMP:BHF-UCL.::GO:0010976; P:positive regulation of neuron projection development; IMP:BHF-UCL.::GO:0032532; P:regulation of microvillus length; IC:BHF-UCL.::GO:0042989; P:sequestering of actin monomers; ISS:BHF-UCL. | 91 | Q6GMH3 | 347 | TWF2_DANRE Twinfilin-2 OS=Danio rerio (Zebraf... | 69 | 0.001 | 41.2 | 28 | 54 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | |