| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q4WQ08 | 785 | ADMB_ASPFU Disintegrin and metalloproteinase ... | 677 | 0 | 619 | 48 | 64 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 2 | C5FUK3 | 796 | ADMB_ARTOC Disintegrin and metalloproteinase ... | 689 | 0 | 568 | 44 | 60 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 3 | D4B1G0 | 799 | ADMB_ARTBC Disintegrin and metalloproteinase ... | 692 | 0 | 558 | 43 | 60 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 4 | D4DCV9 | 798 | ADMB_TRIVH Disintegrin and metalloproteinase ... | 692 | 0 | 554 | 43 | 60 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 5 | O13766 | 512 | MDE10_SCHPO Zinc metalloprotease mde10 OS=Sch... | 393 | 7e-62 | 221 | 34 | 50 | GO:0005619; C:ascospore wall; IDA:PomBase.::GO:0009986; C:cell surface; NAS:PomBase.::GO:0005789; C:endoplasmic reticulum membrane; IDA:PomBase. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0030476; P:ascospore wall assembly; IMP:PomBase.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 6 | Q4VM08 | 616 | VM3VA_MACLB Zinc metalloproteinase-disintegri... | 376 | 9e-35 | 144 | 32 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 7 | C9E1S0 | 613 | VM3V3_AGKPL Zinc metalloproteinase-disintegri... | 373 | 2e-34 | 142 | 33 | 47 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 8 | C9E1R8 | 609 | VM3V3_CROVV Zinc metalloproteinase-disintegri... | 368 | 7e-34 | 140 | 30 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 9 | Q90282 | 609 | VM3VB_CROAT Zinc metalloproteinase-disintegri... | 368 | 8e-34 | 140 | 30 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 10 | Q2QA02 | 609 | VM3_CRODD Zinc metalloproteinase-disintegrin ... | 368 | 9e-34 | 140 | 30 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 11 | Q2UXR0 | 614 | VM3E1_ECHOC Zinc metalloproteinase-disintegri... | 545 | 6e-33 | 138 | 28 | 41 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 12 | A4PBQ9 | 607 | VM3VA_CROAT Zinc metalloproteinase-disintegri... | 285 | 8e-32 | 135 | 34 | 47 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 13 | P30431 | 571 | VM3JA_BOTJA Zinc metalloproteinase-disintegri... | 286 | 2e-30 | 130 | 33 | 47 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 14 | Q61072 | 845 | ADAM9_MOUSE Disintegrin and metalloproteinase... | 369 | 4e-30 | 130 | 29 | 44 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005615; C:extracellular space; IMP:BHF-UCL.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031233; C:intrinsic to external side of plasma membrane; IDA:BHF-UCL. | | | | | | | | | | GO:0005080; F:protein kinase C binding; IPI:BHF-UCL.::GO:0017124; F:SH3 domain binding; IDA:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IDA:BHF-UCL.::GO:0051384; P:response to glucocorticoid stimulus; IMP:BHF-UCL.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IMP:BHF-UCL. | 15 | Q8QG88 | 610 | VM36A_BOTIN Zinc metalloproteinase-disintegri... | 286 | 1e-29 | 128 | 31 | 46 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 16 | O93523 | 610 | VM3BP_BOTJA Zinc metalloproteinase-disintegri... | 286 | 2e-29 | 127 | 31 | 46 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 17 | Q2UXQ5 | 613 | VM3E2_ECHOC Zinc metalloproteinase-disintegri... | 372 | 2e-28 | 124 | 30 | 45 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0016504; F:peptidase activator activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 18 | Q90495 | 616 | VM3E_ECHCA Zinc metalloproteinase-disintegrin... | 391 | 2e-28 | 124 | 29 | 42 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0016504; F:peptidase activator activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 19 | Q9W6M5 | 610 | VM3AH_DEIAC Zinc metalloproteinase-disintegri... | 288 | 5e-28 | 123 | 32 | 48 | GO:0005576; C:extracellular region; IEA:UniProtKB-KW.::GO:0044421; C:extracellular region part; ISS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 20 | Q05910 | 826 | ADAM8_MOUSE Disintegrin and metalloproteinase... | 372 | 7e-28 | 124 | 30 | 41 | GO:0071133; C:alpha9-beta1 integrin-ADAM8 complex; IDA:BHF-UCL.::GO:0032127; C:dense core granule membrane; ISS:BHF-UCL.::GO:0005887; C:integral to plasma membrane; ISS:BHF-UCL.::GO:0032010; C:phagolysosome; ISS:BHF-UCL.::GO:0002102; C:podosome; ISS:BHF-UCL.::GO:0042581; C:specific granule; ISS:BHF-UCL.::GO:0070820; C:tertiary granule; ISS:BHF-UCL. | | | | | | | | | | GO:0005509; F:calcium ion binding; IDA:BHF-UCL.::GO:0050839; F:cell adhesion molecule binding; IPI:BHF-UCL.::GO:0005178; F:integrin binding; TAS:BHF-UCL.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IDA:BHF-UCL. | | | | | | | | | | GO:0035419; P:activation of MAPK activity involved in innate immune response; IDA:BHF-UCL.::GO:0001525; P:angiogenesis; IDA:BHF-UCL.::GO:0043534; P:blood vessel endothelial cell migration; NAS:BHF-UCL.::GO:0000902; P:cell morphogenesis; IMP:BHF-UCL.::GO:0016337; P:cell-cell adhesion; IDA:MGI.::GO:0007160; P:cell-matrix adhesion; TAS:BHF-UCL.::GO:0006944; P:cellular membrane fusion; TAS:BHF-UCL.::GO:0071456; P:cellular response to hypoxia; ISS:BHF-UCL.::GO:0002523; P:leukocyte migration involved in inflammatory response; IMP:BHF-UCL.::GO:0048247; P:lymphocyte chemotaxis; IDA:BHF-UCL.::GO:0043524; P:negative regulation of neuron apoptotic process; IDA:BHF-UCL.::GO:2000399; P:negative regulation of thymocyte aggregation; NAS:BHF-UCL.::GO:0072675; P:osteoclast fusion; TAS:BHF-UCL.::GO:0002675; P:positive regulation of acute inflammatory response; IMP:BHF-UCL.::GO:0045780; P:positive regulation of bone resorption; IDA:BHF-UCL.::GO:0045785; P:positive regulation of cell adhesion; IDA:BHF-UCL.::GO:0002693; P:positive regulation of cellular extravasation; IMP:BHF-UCL.::GO:2000418; P:positive regulation of eosinophil migration; IMP:BHF-UCL.::GO:2000415; P:positive regulation of fibronectin-dependent thymocyte migration; IMP:BHF-UCL.::GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IDA:BHF-UCL.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:BHF-UCL.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IDA:BHF-UCL.::GO:0033089; P:positive regulation of T cell differentiation in thymus; IDA:BHF-UCL.::GO:0070245; P:positive regulation of thymocyte apoptotic process; IMP:BHF-UCL.::GO:2000309; P:positive regulation of tumor necrosis factor (ligand) superfamily member 11 production; IMP:BHF-UCL.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0045670; P:regulation of osteoclast differentiation; NAS:BHF-UCL.::GO:0048729; P:tissue morphogenesis; TAS:BHF-UCL. | 21 | D5LMJ3 | 607 | VM3A_NAJAT Zinc metalloproteinase-disintegrin... | 367 | 1e-27 | 122 | 30 | 41 | | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 22 | Q8UVG0 | 612 | VM3BE_BOTER Zinc metalloproteinase-disintegri... | 376 | 1e-27 | 122 | 29 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0016504; F:peptidase activator activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 23 | Q7T046 | 612 | VM3CX_MACLB Coagulation factor X-activating e... | 298 | 1e-27 | 122 | 33 | 46 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 24 | Q9R159 | 760 | ADA25_MOUSE Disintegrin and metalloproteinase... | 296 | 1e-27 | 122 | 30 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW. | 25 | A8QL59 | 621 | VM3_NAJAT Zinc metalloproteinase-disintegrin ... | 368 | 2e-27 | 121 | 29 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 26 | Q13443 | 819 | ADAM9_HUMAN Disintegrin and metalloproteinase... | 437 | 4e-27 | 121 | 27 | 40 | GO:0005615; C:extracellular space; ISS:BHF-UCL.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031233; C:intrinsic to external side of plasma membrane; ISS:BHF-UCL. | | | | | | | | | | GO:0005518; F:collagen binding; IMP:BHF-UCL.::GO:0005178; F:integrin binding; IDA:BHF-UCL.::GO:0043236; F:laminin binding; IMP:BHF-UCL.::GO:0004222; F:metalloendopeptidase activity; IDA:BHF-UCL.::GO:0005080; F:protein kinase C binding; ISS:BHF-UCL.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000186; P:activation of MAPKK activity; IDA:BHF-UCL.::GO:0033631; P:cell-cell adhesion mediated by integrin; IEP:BHF-UCL.::GO:0007160; P:cell-matrix adhesion; IMP:BHF-UCL.::GO:0007229; P:integrin-mediated signaling pathway; IC:BHF-UCL.::GO:0030216; P:keratinocyte differentiation; IEP:BHF-UCL.::GO:0042117; P:monocyte activation; IMP:BHF-UCL.::GO:0051088; P:PMA-inducible membrane protein ectodomain proteolysis; TAS:BHF-UCL.::GO:0033630; P:positive regulation of cell adhesion mediated by integrin; IMP:BHF-UCL.::GO:0051549; P:positive regulation of keratinocyte migration; IMP:BHF-UCL.::GO:0034241; P:positive regulation of macrophage fusion; IMP:BHF-UCL.::GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; ISS:BHF-UCL.::GO:0050714; P:positive regulation of protein secretion; IDA:BHF-UCL.::GO:0051592; P:response to calcium ion; IMP:BHF-UCL.::GO:0051384; P:response to glucocorticoid stimulus; ISS:BHF-UCL.::GO:0042542; P:response to hydrogen peroxide; IMP:BHF-UCL.::GO:0010042; P:response to manganese ion; IMP:BHF-UCL.::GO:0034612; P:response to tumor necrosis factor; IDA:BHF-UCL.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IMP:BHF-UCL. | 27 | Q98UF9 | 606 | VM3H3_BOTJA Zinc metalloproteinase-disintegri... | 351 | 4e-27 | 120 | 30 | 45 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 28 | Q92043 | 419 | VM3AA_CROAT Zinc metalloproteinase-disintegri... | 374 | 5e-27 | 118 | 31 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 29 | Q9PVK7 | 600 | VM3_NAJKA Zinc metalloproteinase-disintegrin ... | 376 | 5e-27 | 120 | 28 | 43 | | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 30 | P0C7B0 | 610 | VM3H6_GLOBR Zinc metalloproteinase-disintegri... | 290 | 9e-27 | 119 | 32 | 46 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 31 | Q9DGB9 | 610 | VM3V1_CROAT Zinc metalloproteinase-disintegri... | 366 | 1e-26 | 119 | 30 | 45 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. |
