rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | Q9P0K1 | 906 | ADA22_HUMAN Disintegrin and metalloproteinase... | 164 | 2e-19 | 97.1 | 37 | 52 | GO:0016021; C:integral to membrane; NAS:UniProtKB. | | | | | | | | | | GO:0005178; F:integrin binding; NAS:UniProtKB.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0007162; P:negative regulation of cell adhesion; NAS:UniProtKB.::GO:0006508; P:proteolysis; IEA:InterPro. | 92 | Q60472 | 777 | ADAM5_CAVPO Disintegrin and metalloproteinase... | 186 | 2e-19 | 97.1 | 33 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 93 | Q60411 | 735 | ADAM2_CAVPO Disintegrin and metalloproteinase... | 383 | 3e-19 | 96.3 | 26 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro. | 94 | Q9R1V6 | 904 | ADA22_MOUSE Disintegrin and metalloproteinase... | 164 | 4e-19 | 95.9 | 37 | 52 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008344; P:adult locomotory behavior; IMP:MGI.::GO:0022011; P:myelination in peripheral nervous system; IMP:MGI.::GO:0006508; P:proteolysis; IEA:InterPro. | 95 | P82942 | 401 | VM3K_NAJKA Hemorrhagic metalloproteinase-disi... | 286 | 4e-19 | 93.6 | 28 | 42 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 96 | P97776 | 445 | ADA18_RAT Disintegrin and metalloproteinase d... | 255 | 4e-19 | 94.4 | 31 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW. | 97 | P0C6R9 | 196 | VM3A_BOTAL Zinc metalloproteinase-disintegrin... | 125 | 5e-19 | 90.9 | 43 | 56 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 98 | Q9UKJ8 | 722 | ADA21_HUMAN Disintegrin and metalloproteinase... | 359 | 5e-19 | 95.5 | 25 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0007338; P:single fertilization; TAS:ProtInc. | 99 | O73795 | 505 | VM2MB_GLOBR Zinc metalloproteinase/disintegri... | 334 | 6e-19 | 94.4 | 28 | 40 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 100 | D3TTC1 | 593 | VM3KL_NAJAT Zinc metalloproteinase-disintegri... | 286 | 8e-19 | 94.4 | 29 | 41 | | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 101 | Q0NZX9 | 218 | VM3B2_BOTJA Zinc metalloproteinase-disintegri... | 125 | 1e-18 | 90.5 | 44 | 58 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 102 | O88839 | 864 | ADA15_MOUSE Disintegrin and metalloproteinase... | 211 | 2e-18 | 94 | 31 | 46 | GO:0001669; C:acrosomal vesicle; IEA:UniProtKB-SubCell.::GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0019861; C:flagellum; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0060317; P:cardiac epithelial to mesenchymal transition; IMP:MGI.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0030574; P:collagen catabolic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 103 | Q60718 | 735 | ADAM2_MOUSE Disintegrin and metalloproteinase... | 460 | 2e-18 | 93.6 | 25 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030534; P:adult behavior; IMP:MGI.::GO:0007155; P:cell adhesion; IGI:MGI.::GO:0006508; P:proteolysis; IEA:InterPro.::GO:0008542; P:visual learning; IMP:MGI. | 104 | O35227 | 788 | ADAM7_MOUSE Disintegrin and metalloproteinase... | 368 | 2e-18 | 93.2 | 26 | 38 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 105 | O35674 | 920 | ADA19_MOUSE Disintegrin and metalloproteinase... | 372 | 3e-18 | 93.2 | 29 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007507; P:heart development; IMP:MGI.::GO:0006509; P:membrane protein ectodomain proteolysis; IMP:MGI. | 106 | O43184 | 909 | ADA12_HUMAN Disintegrin and metalloproteinase... | 370 | 4e-18 | 92.8 | 27 | 41 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:BHF-UCL. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0007520; P:myoblast fusion; TAS:ProtInc.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 107 | P0C6B6 | 484 | VM2AL_CRYAB Zinc metalloproteinase homolog/di... | 174 | 4e-18 | 91.7 | 37 | 47 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 108 | Q95194 | 746 | ADA18_MACFA Disintegrin and metalloproteinase... | 176 | 5e-18 | 92.4 | 34 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW. | 109 | Q9Y3Q7 | 739 | ADA18_HUMAN Disintegrin and metalloproteinase... | 175 | 5e-18 | 92 | 34 | 52 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; TAS:ProtInc. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro.::GO:0007283; P:spermatogenesis; TAS:ProtInc. | 110 | Q9QYV0 | 864 | ADA15_RAT Disintegrin and metalloproteinase d... | 213 | 7e-18 | 92 | 32 | 45 | GO:0001669; C:acrosomal vesicle; IEA:UniProtKB-SubCell.::GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0019861; C:flagellum; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; TAS:RGD.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0016337; P:cell-cell adhesion; TAS:RGD.::GO:0030574; P:collagen catabolic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0042246; P:tissue regeneration; IEP:RGD. | 111 | Q9R157 | 719 | ADA18_MOUSE Disintegrin and metalloproteinase... | 164 | 9e-18 | 91.3 | 34 | 52 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW. | 112 | Q63180 | 789 | ADAM7_RAT Disintegrin and metalloproteinase d... | 372 | 1e-17 | 91.3 | 25 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro.::GO:0007283; P:spermatogenesis; NAS:RGD. | 113 | O42596 | 935 | ADA22_XENLA Disintegrin and metalloproteinase... | 165 | 1e-17 | 91.3 | 35 | 53 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 114 | Q7SZD9 | 478 | VM2US_GLOUS Zinc metalloproteinase/disintegri... | 336 | 2e-17 | 89.7 | 29 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 115 | P0C6E4 | 483 | VM2JN_PROJR Zinc metalloproteinase/disintegri... | 331 | 2e-17 | 89.7 | 28 | 40 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 116 | Q7SZE0 | 483 | VM2SA_GLOSA Zinc metalloproteinase/disintegri... | 335 | 2e-17 | 89.4 | 26 | 41 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 117 | D6PXE8 | 593 | VM3B_NAJAT Zinc metalloproteinase-disintegrin... | 286 | 3e-17 | 89.7 | 28 | 41 | | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 118 | Q9R1V7 | 829 | ADA23_MOUSE Disintegrin and metalloproteinase... | 174 | 3e-17 | 90.1 | 33 | 49 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro. | 119 | Q90YA6 | 481 | VM2E2_PROEL Zinc metalloproteinase/disintegri... | 249 | 5e-17 | 88.2 | 30 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 120 | Q60813 | 791 | ADM1A_MOUSE Disintegrin and metalloproteinase... | 247 | 5e-17 | 89.4 | 28 | 42 | GO:0016021; C:integral to membrane; NAS:UniProtKB.::GO:0045121; C:membrane raft; IDA:MGI. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007339; P:binding of sperm to zona pellucida; IMP:MGI.::GO:0007342; P:fusion of sperm to egg plasma membrane; NAS:UniProtKB.::GO:0006508; P:proteolysis; NAS:UniProtKB. | 121 | Q5XUW8 | 476 | VM2IA_BOTIN Zinc metalloproteinase/disintegri... | 334 | 5e-17 | 88.2 | 27 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0016504; F:peptidase activator activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. |