| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q9DGB9 | 610 | VM3V1_CROAT Zinc metalloproteinase-disintegri... | 366 | 1e-26 | 119 | 30 | 45 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 32 | A8QL48 | 605 | VM3_BUNFA Zinc metalloproteinase-disintegrin ... | 377 | 2e-26 | 118 | 30 | 42 | GO:0005576; C:extracellular region; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 33 | Q90ZI3 | 612 | VM3H1_PROFL Zinc metalloproteinase-disintegri... | 367 | 2e-26 | 118 | 29 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0016504; F:peptidase activator activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 34 | A8QL49 | 614 | VM3_BUNMU Zinc metalloproteinase-disintegrin ... | 291 | 1e-25 | 115 | 33 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 35 | D3TTC2 | 613 | VM3H_NAJAT Zinc metalloproteinase-disintegrin... | 291 | 1e-25 | 115 | 32 | 45 | | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 36 | Q9UKQ2 | 775 | ADA28_HUMAN Disintegrin and metalloproteinase... | 359 | 2e-25 | 116 | 29 | 40 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; TAS:ProtInc. | 37 | P20164 | 614 | VM3HB_PROFL Zinc metalloproteinase/disintegri... | 349 | 2e-25 | 115 | 30 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 38 | Q1PS45 | 608 | VM3AK_DEIAC Zinc metalloprotease-disintegrin ... | 369 | 5e-25 | 114 | 29 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 39 | Q9XSL6 | 776 | ADA28_MACFA Disintegrin and metalloproteinase... | 357 | 7e-25 | 114 | 29 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 40 | Q4VM07 | 614 | VM3VB_MACLB Zinc metalloproteinase-disintegri... | 377 | 9e-25 | 113 | 29 | 42 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 41 | Q8JIR2 | 609 | VM3HA_PROFL Zinc metalloproteinase/disintegri... | 374 | 1e-24 | 113 | 29 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; TAS:UniProtKB. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0030195; P:negative regulation of blood coagulation; IDA:UniProtKB.::GO:0006508; P:proteolysis; IDA:UniProtKB. | 42 | Q2LD49 | 621 | VM3TM_VIRST Zinc metalloproteinase-disintegri... | 382 | 1e-24 | 112 | 30 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 43 | Q10749 | 609 | VM3M1_NAJMO Zinc metalloproteinase mocarhagin... | 285 | 1e-24 | 112 | 31 | 45 | GO:0005576; C:extracellular region; IDA:UniProtKB. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0030195; P:negative regulation of blood coagulation; IDA:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 44 | O42138 | 620 | VM3AD_AGKCL Zinc metalloproteinase-disintegri... | 367 | 2e-24 | 112 | 28 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0016504; F:peptidase activator activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 45 | Q7LZ61 | 619 | VM3CX_DABRU Coagulation factor X-activating e... | 295 | 3e-24 | 111 | 31 | 45 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 46 | B8K1W0 | 615 | VM3DK_DABRR Zinc metalloproteinase-disintegri... | 353 | 3e-24 | 111 | 27 | 42 | GO:0005576; C:extracellular region; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 47 | Q9UKF5 | 820 | ADA29_HUMAN Disintegrin and metalloproteinase... | 213 | 4e-24 | 111 | 32 | 45 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro.::GO:0007283; P:spermatogenesis; TAS:ProtInc. | 48 | Q8AWI5 | 610 | VM3HA_GLOHA Zinc metalloprotease-disintegrin ... | 366 | 5e-24 | 110 | 29 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 49 | P78325 | 824 | ADAM8_HUMAN Disintegrin and metalloproteinase... | 364 | 5e-24 | 111 | 27 | 41 | GO:0071133; C:alpha9-beta1 integrin-ADAM8 complex; ISS:BHF-UCL.::GO:0009986; C:cell surface; IDA:BHF-UCL.::GO:0032127; C:dense core granule membrane; IDA:BHF-UCL.::GO:0005887; C:integral to plasma membrane; IDA:BHF-UCL.::GO:0032010; C:phagolysosome; IDA:BHF-UCL.::GO:0002102; C:podosome; IDA:BHF-UCL.::GO:0042581; C:specific granule; IDA:BHF-UCL.::GO:0070820; C:tertiary granule; IDA:BHF-UCL. | | | | | | | | | | GO:0005509; F:calcium ion binding; ISS:BHF-UCL.::GO:0050839; F:cell adhesion molecule binding; IPI:BHF-UCL.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0043621; F:protein self-association; TAS:BHF-UCL.::GO:0008270; F:zinc ion binding; TAS:BHF-UCL. | | | | | | | | | | GO:0035419; P:activation of MAPK activity involved in innate immune response; ISS:BHF-UCL.::GO:0001525; P:angiogenesis; ISS:BHF-UCL.::GO:0000902; P:cell morphogenesis; ISS:BHF-UCL.::GO:0071456; P:cellular response to hypoxia; IDA:BHF-UCL.::GO:0002523; P:leukocyte migration involved in inflammatory response; ISS:BHF-UCL.::GO:0048247; P:lymphocyte chemotaxis; ISS:BHF-UCL.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:BHF-UCL.::GO:0002675; P:positive regulation of acute inflammatory response; ISS:BHF-UCL.::GO:0045780; P:positive regulation of bone resorption; ISS:BHF-UCL.::GO:0045785; P:positive regulation of cell adhesion; ISS:BHF-UCL.::GO:2000418; P:positive regulation of eosinophil migration; ISS:BHF-UCL.::GO:2000415; P:positive regulation of fibronectin-dependent thymocyte migration; ISS:BHF-UCL.::GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IDA:BHF-UCL.::GO:2000391; P:positive regulation of neutrophil extravasation; IDA:BHF-UCL.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:BHF-UCL.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; ISS:BHF-UCL.::GO:0010954; P:positive regulation of protein processing; NAS:BHF-UCL.::GO:0050714; P:positive regulation of protein secretion; IC:BHF-UCL.::GO:0033089; P:positive regulation of T cell differentiation in thymus; ISS:BHF-UCL.::GO:0070245; P:positive regulation of thymocyte apoptotic process; ISS:BHF-UCL.::GO:2000309; P:positive regulation of tumor necrosis factor (ligand) superfamily member 11 production; ISS:BHF-UCL.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0022407; P:regulation of cell-cell adhesion; IDA:BHF-UCL. | 50 | Q9R158 | 697 | AD26A_MOUSE Disintegrin and metalloproteinase... | 296 | 7e-24 | 110 | 29 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW. | 51 | O93518 | 190 | VM3S5_GLOBR Zinc metalloproteinase/disintegri... | 124 | 1e-23 | 103 | 44 | 56 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 52 | Q9R160 | 761 | ADA24_MOUSE Disintegrin and metalloproteinase... | 391 | 2e-23 | 109 | 26 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW. | 53 | Q923W9 | 797 | ADA33_MOUSE Disintegrin and metalloproteinase... | 372 | 2e-23 | 109 | 28 | 42 | GO:0016021; C:integral to membrane; NAS:UniProtKB. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; NAS:UniProtKB. | | | | | | | | | | GO:0006508; P:proteolysis; NAS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; NAS:UniProtKB.::GO:0042035; P:regulation of cytokine biosynthetic process; NAS:UniProtKB. | 54 | A3R0T9 | 611 | VM3_OPHHA Zinc metalloproteinase-disintegrin ... | 373 | 2e-23 | 108 | 27 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 55 | Q9JLN6 | 793 | ADA28_MOUSE Disintegrin and metalloproteinase... | 299 | 4e-23 | 108 | 30 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 56 | D8VNS0 | 615 | VM3_CERRY Zinc metalloproteinase-disintegrin ... | 446 | 5e-23 | 107 | 26 | 39 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 57 | Q3HTN2 | 600 | VM3SB_VIRST Zinc metalloproteinase-disintegri... | 370 | 5e-23 | 107 | 30 | 45 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 58 | O77780 | 745 | ADAM2_BOVIN Disintegrin and metalloproteinase... | 369 | 8e-23 | 107 | 27 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro. | 59 | Q28660 | 751 | ADAM2_RABIT Disintegrin and metalloproteinase... | 365 | 1e-22 | 107 | 28 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro. | 60 | Q1PHZ4 | 547 | VM3B1_BOTJR Zinc metalloproteinase-disintegri... | 375 | 2e-22 | 105 | 27 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 61 | O35598 | 749 | ADA10_MOUSE Disintegrin and metalloproteinase... | 380 | 2e-22 | 106 | 27 | 40 | GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0005798; C:Golgi-associated vesicle; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0014069; C:postsynaptic density; IDA:MGI. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IDA:UniProtKB.::GO:0042169; F:SH2 domain binding; NAS:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0001701; P:in utero embryonic development; IMP:UniProtKB.::GO:0007162; P:negative regulation of cell adhesion; ISS:UniProtKB.::GO:0007220; P:Notch receptor processing; NAS:UniProtKB.::GO:0007219; P:Notch signaling pathway; IMP:UniProtKB.::GO:0006913; P:nucleocytoplasmic transport; NAS:UniProtKB.::GO:0006468; P:protein phosphorylation; IDA:UniProtKB. |
