| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
151 | Q805F6 | 483 | VM2AB_AGKCO Zinc metalloproteinase/disintegri... | 339 | 0.00000000000002 | 79.7 | 27 | 42 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 152 | E9NW27 | 484 | VM2P2_PROMU Zinc metalloproteinase/disintegri... | 337 | 0.00000000000008 | 78.2 | 26 | 39 | GO:0005576; C:extracellular region; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 153 | P31989 | 161 | VM2JC_BOTJA Zinc metalloproteinase/disintegri... | 176 | 0.0000000000001 | 73.9 | 33 | 48 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 154 | Q8TC27 | 787 | ADA32_HUMAN Disintegrin and metalloproteinase... | 398 | 0.0000000000001 | 78.2 | 24 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 155 | Q805F4 | 483 | VM2PB_AGKPI Zinc metalloproteinase/disintegri... | 339 | 0.0000000000002 | 77 | 27 | 40 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 156 | Q9PSZ3 | 452 | ADA11_XENLA Disintegrin and metalloproteinase... | 129 | 0.0000000000002 | 76.6 | 37 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 157 | O93515 | 146 | VM2S3_GLOBR Zinc metalloproteinase/disintegri... | 152 | 0.0000000000003 | 72.4 | 38 | 49 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 158 | C9E1S1 | 483 | VM2V2_AGKPL Zinc metalloproteinase/disintegri... | 339 | 0.0000000000005 | 75.5 | 27 | 40 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0042730; P:fibrinolysis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 159 | O93517 | 105 | VM3S4_GLOBR Zinc metalloproteinase/disintegri... | 97 | 0.0000000000008 | 70.5 | 46 | 57 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 160 | P17497 | 83 | DISI_BITAR Disintegrin bitan OS=Bitis arietan... | 83 | 0.0000000000008 | 69.7 | 52 | 64 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 161 | Q9VAC5 | 732 | ADA17_DROME ADAM 17-like protease OS=Drosophi... | 231 | 0.000000000004 | 73.2 | 29 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 162 | P78536 | 824 | ADA17_HUMAN Disintegrin and metalloproteinase... | 229 | 0.00000000001 | 71.6 | 29 | 42 | GO:0015629; C:actin cytoskeleton; IDA:BHF-UCL.::GO:0016324; C:apical plasma membrane; IDA:BHF-UCL.::GO:0009986; C:cell surface; IDA:BHF-UCL.::GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005887; C:integral to plasma membrane; IDA:BHF-UCL.::GO:0045121; C:membrane raft; IDA:BHF-UCL. | | | | | | | | | | GO:0005178; F:integrin binding; IPI:BHF-UCL.::GO:0005138; F:interleukin-6 receptor binding; IPI:BHF-UCL.::GO:0004222; F:metalloendopeptidase activity; IDA:BHF-UCL.::GO:0030165; F:PDZ domain binding; IPI:BHF-UCL.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030183; P:B cell differentiation; ISS:BHF-UCL.::GO:0033627; P:cell adhesion mediated by integrin; IDA:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; IDA:BHF-UCL.::GO:0035625; P:epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway; IMP:BHF-UCL.::GO:0002467; P:germinal center formation; ISS:BHF-UCL.::GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.::GO:0031293; P:membrane protein intracellular domain proteolysis; TAS:Reactome.::GO:0032717; P:negative regulation of interleukin-8 production; IMP:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0002446; P:neutrophil mediated immunity; IC:BHF-UCL.::GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.::GO:0051088; P:PMA-inducible membrane protein ectodomain proteolysis; IDA:BHF-UCL.::GO:0030307; P:positive regulation of cell growth; IMP:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.::GO:0032722; P:positive regulation of chemokine production; IMP:BHF-UCL.::GO:0031659; P:positive regulation of cyclin-dependent protein kinase activity involved in G1/S; IDA:BHF-UCL.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:BHF-UCL.::GO:0010820; P:positive regulation of T cell chemotaxis; IMP:BHF-UCL.::GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; ISS:BHF-UCL.::GO:0033025; P:regulation of mast cell apoptotic process; ISS:BHF-UCL.::GO:0042493; P:response to drug; ISS:BHF-UCL.::GO:0055099; P:response to high density lipoprotein particle stimulus; IDA:BHF-UCL.::GO:0001666; P:response to hypoxia; IDA:BHF-UCL.::GO:0032496; P:response to lipopolysaccharide; IDA:BHF-UCL.::GO:0048536; P:spleen development; ISS:BHF-UCL.::GO:0033077; P:T cell differentiation in thymus; ISS:BHF-UCL.::GO:0035313; P:wound healing, spreading of epidermal cells; IEP:BHF-UCL. | 163 | Q9Z1K9 | 827 | ADA17_RAT Disintegrin and metalloproteinase d... | 217 | 0.00000000003 | 70.5 | 29 | 43 | GO:0009986; C:cell surface; IDA:RGD. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IMP:RGD.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IDA:RGD.::GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW. | 164 | Q9Z0F8 | 827 | ADA17_MOUSE Disintegrin and metalloproteinase... | 217 | 0.00000000003 | 70.5 | 29 | 43 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005576; C:extracellular region; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; TAS:Reactome.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030183; P:B cell differentiation; IMP:BHF-UCL.::GO:0048870; P:cell motility; IMP:BHF-UCL.::GO:0002467; P:germinal center formation; IMP:BHF-UCL.::GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.::GO:0051088; P:PMA-inducible membrane protein ectodomain proteolysis; IDA:BHF-UCL.::GO:0051272; P:positive regulation of cellular component movement; IMP:BHF-UCL.::GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IMP:BHF-UCL.::GO:0033025; P:regulation of mast cell apoptotic process; IMP:BHF-UCL.::GO:0042493; P:response to drug; IMP:BHF-UCL.::GO:0048536; P:spleen development; IMP:BHF-UCL.::GO:0033077; P:T cell differentiation in thymus; IMP:BHF-UCL. | 165 | Q0NZX5 | 88 | DISJA_BOTJA Disintegrin jarastatin OS=Bothrop... | 91 | 0.0000000002 | 63.2 | 44 | 55 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006935; P:chemotaxis; IEA:UniProtKB-KW. | 166 | Q9IAX6 | 466 | VM2M2_DEIAC Zinc metalloproteinase/disintegri... | 256 | 0.0000000002 | 67 | 29 | 42 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 167 | Q98995 | 478 | VM2L2_MACLB Zinc metalloproteinase/disintegri... | 256 | 0.0000000003 | 66.6 | 28 | 41 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0042730; P:fibrinolysis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 168 | P23323 | 75 | DISC_PROFL Disintegrin CTF-II OS=Protobothrop... | 77 | 0.0000000008 | 60.8 | 44 | 56 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 169 | Q9PWJ0 | 479 | VM2A2_DEIAC Zinc metalloproteinase/disintegri... | 334 | 0.000000002 | 64.3 | 26 | 40 | GO:0044421; C:extracellular region part; ISS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 170 | Q805F5 | 111 | DISA_AGKPI Disintegrin piscivostatin-alpha OS... | 63 | 0.000000002 | 60.5 | 48 | 56 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 171 | O93516 | 108 | VM2S2_GLOBR Zinc metalloproteinase/disintegri... | 91 | 0.000000004 | 59.7 | 40 | 54 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 172 | C9E1S2 | 111 | DIS_AGKPL Disintegrin-alpha OS=leucostoma). G... | 63 | 0.000000004 | 59.7 | 46 | 56 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 173 | Q698K8 | 76 | DISA_GLOBR Disintegrin adinbitor OS=brevicaud... | 80 | 0.000000007 | 58.2 | 45 | 55 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW. | 174 | P31988 | 72 | DISI_BOTCO Disintegrin cotiarin OS=Bothrops c... | 79 | 0.00000001 | 57.4 | 43 | 56 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 175 | P21858 | 71 | DISI_GLOBL Disintegrin halysin OS=Gloydius bl... | 79 | 0.00000003 | 56.2 | 46 | 54 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 176 | P18618 | 71 | DISI_BOTAT Disintegrin batroxostatin OS=Bothr... | 79 | 0.00000003 | 56.2 | 43 | 56 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 177 | Q7LZI5 | 71 | DISI1_GLOUS Disintegrin ussuristatin-1 OS=uss... | 77 | 0.00000005 | 55.5 | 45 | 56 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 178 | P31985 | 72 | DISI_CROOC Disintegrin cereberin OS=viridis c... | 79 | 0.00000007 | 55.1 | 42 | 53 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 179 | Q6T271 | 325 | VM2BI_BITGA Zinc metalloproteinase/disintegri... | 254 | 0.00000007 | 58.5 | 28 | 41 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 180 | Q9DGH6 | 73 | DISSA_GLOHA Disintegrin saxatilin OS=Gloydius... | 79 | 0.0000001 | 54.7 | 43 | 53 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW. | 181 | P31990 | 73 | DISI_LACMU Disintegrin lachesin OS=Lachesis m... | 79 | 0.0000001 | 54.3 | 41 | 53 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. |
