rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
211 | P35998 | 433 | PRS7_HUMAN 26S protease regulatory subunit 7 ... | 140 | 0.000003 | 53.5 | 29 | 49 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000502; C:proteasome complex; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome. | 212 | Q5E9F9 | 433 | PRS7_BOVIN 26S protease regulatory subunit 7 ... | 140 | 0.000003 | 53.5 | 29 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB. | 213 | Q8JZQ2 | 802 | AFG32_MOUSE AFG3-like protein 2 OS=Mus muscul... | 157 | 0.000003 | 53.9 | 29 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007409; P:axonogenesis; IMP:MGI.::GO:0016265; P:death; IMP:MGI.::GO:0042552; P:myelination; IMP:MGI.::GO:0021675; P:nerve development; IMP:MGI.::GO:0007528; P:neuromuscular junction development; IMP:MGI.::GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0040014; P:regulation of multicellular organism growth; IMP:MGI.::GO:0060013; P:righting reflex; IMP:MGI. | 214 | D0LWB8 | 682 | FTSH_HALO1 ATP-dependent zinc metalloprotease... | 151 | 0.000003 | 53.5 | 28 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 215 | Q67T82 | 587 | FTSH2_SYMTH ATP-dependent zinc metalloproteas... | 155 | 0.000003 | 53.5 | 29 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 216 | Q9Y4W6 | 797 | AFG32_HUMAN AFG3-like protein 2 OS=Homo sapie... | 157 | 0.000003 | 53.5 | 29 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0051082; F:unfolded protein binding; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 217 | B7T1V0 | 644 | FTSH_VAULI ATP-dependent zinc metalloprotease... | 145 | 0.000003 | 53.5 | 28 | 46 | GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 218 | B1ZMG6 | 614 | FTSH_OPITP ATP-dependent zinc metalloprotease... | 185 | 0.000003 | 53.5 | 29 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 219 | Q98PE4 | 725 | FTSH_MYCPU ATP-dependent zinc metalloprotease... | 165 | 0.000003 | 53.5 | 30 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 220 | O15381 | 856 | NVL_HUMAN Nuclear valosin-containing protein-... | 133 | 0.00005 | 49.7 | 31 | 48 | GO:0016235; C:aggresome; IDA:HPA.::GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; TAS:ProtInc.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | | 221 | Q9BVQ7 | 753 | SPA5L_HUMAN Spermatogenesis-associated protei... | 167 | 0.002 | 44.3 | 29 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | | 222 | Q58576 | 430 | PAN_METJA Proteasome-activating nucleotidase ... | 149 | 0.000004 | 52.8 | 30 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0022623; C:proteasome-activating nucleotidase complex; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IDA:UniProtKB.::GO:0043273; F:CTPase activity; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:UniProtKB. | | | | | | | | | | GO:0010498; P:proteasomal protein catabolic process; IDA:UniProtKB.::GO:0043335; P:protein unfolding; IDA:UniProtKB. | 223 | O80860 | 695 | FTSH2_ARATH ATP-dependent zinc metalloproteas... | 149 | 0.000004 | 53.1 | 28 | 46 | GO:0009941; C:chloroplast envelope; IDA:TAIR.::GO:0009535; C:chloroplast thylakoid membrane; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031977; C:thylakoid lumen; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0010205; P:photoinhibition; IMP:TAIR.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0010304; P:PSII associated light-harvesting complex II catabolic process; TAS:TAIR.::GO:0072593; P:reactive oxygen species metabolic process; IDA:TAIR.::GO:0010027; P:thylakoid membrane organization; IMP:TAIR. | 224 | A6TSZ1 | 590 | FTSH1_ALKMQ ATP-dependent zinc metalloproteas... | 153 | 0.000004 | 53.1 | 29 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 225 | Q03Z46 | 700 | FTSH_LEUMM ATP-dependent zinc metalloprotease... | 151 | 0.000004 | 53.1 | 28 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 226 | A9EXK6 | 648 | FTSH4_SORC5 ATP-dependent zinc metalloproteas... | 126 | 0.000004 | 53.1 | 30 | 52 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 227 | Q655S1 | 676 | FTSH2_ORYSJ ATP-dependent zinc metalloproteas... | 149 | 0.000004 | 53.1 | 28 | 46 | GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 228 | A1RWU6 | 413 | RFCL_THEPD Replication factor C large subunit... | 154 | 0.000004 | 52.8 | 28 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006260; P:DNA replication; IEA:UniProtKB-KW. | 229 | P75120 | 709 | FTSH_MYCPN ATP-dependent zinc metalloprotease... | 181 | 0.000004 | 53.1 | 28 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 230 | O28303 | 398 | PAN_ARCFU Proteasome-activating nucleotidase ... | 149 | 0.000004 | 52.4 | 29 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0030163; P:protein catabolic process; IEA:InterPro. | 231 | O74445 | 388 | PRS10_SCHPO Probable 26S protease subunit rpt... | 150 | 0.000004 | 52.4 | 30 | 49 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0008540; C:proteasome regulatory particle, base subcomplex; ISS:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:PomBase.::GO:0004175; F:endopeptidase activity; ISS:PomBase.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; NAS:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase. | 232 | P46468 | 1229 | CDAT_PLAF7 Putative cell division cycle ATPas... | 143 | 0.001 | 45.4 | 27 | 41 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:GeneDB_Pfalciparum. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051726; P:regulation of cell cycle; ISS:GeneDB_Pfalciparum. | 233 | A8ZNZ4 | 655 | FTSH_ACAM1 ATP-dependent zinc metalloprotease... | 196 | 0.000005 | 52.8 | 29 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0042651; C:thylakoid membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 234 | Q8LQJ9 | 709 | FTSH4_ORYSJ ATP-dependent zinc metalloproteas... | 126 | 0.000005 | 52.8 | 32 | 49 | GO:0016020; C:membrane; IEA:InterPro.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 235 | Q8U4H3 | 396 | PAN_PYRFU Proteasome-activating nucleotidase ... | 149 | 0.000005 | 52.4 | 28 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0030163; P:protein catabolic process; IEA:InterPro. | 236 | Q9WZ49 | 610 | FTSH_THEMA ATP-dependent zinc metalloprotease... | 159 | 0.000005 | 52.8 | 30 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 237 | Q8W585 | 685 | FTSH8_ARATH ATP-dependent zinc metalloproteas... | 149 | 0.000005 | 52.8 | 28 | 46 | GO:0009941; C:chloroplast envelope; IDA:TAIR.::GO:0009535; C:chloroplast thylakoid membrane; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0010304; P:PSII associated light-harvesting complex II catabolic process; TAS:TAIR. | 238 | Q1PDW5 | 688 | FTSH6_ARATH ATP-dependent zinc metalloproteas... | 190 | 0.000005 | 52.8 | 27 | 43 | GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0010304; P:PSII associated light-harvesting complex II catabolic process; IEP:TAIR. | 239 | A6QBN8 | 671 | FTSH_SULNB ATP-dependent zinc metalloprotease... | 155 | 0.000005 | 52.8 | 30 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 240 | A7YSY2 | 767 | SPA5L_BOVIN Spermatogenesis-associated protei... | 224 | 0.000005 | 52.8 | 29 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | | 241 | Q9DBY8 | 855 | NVL_MOUSE Nuclear valosin-containing protein-... | 133 | 0.0002 | 47.8 | 30 | 47 | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | |