| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
391 | Q5XGP7 | 330 | SKA2A_XENLA Src kinase-associated phosphoprot... | 56 | 0.015 | 42 | 38 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0042113; P:B cell activation; IEA:UniProtKB-KW. | 392 | Q6GPD0 | 1940 | RHG32_XENLA Rho GTPase-activating protein 32 ... | 89 | 0.016 | 42.4 | 29 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 393 | P12931 | 536 | SRC_HUMAN Proto-oncogene tyrosine-protein kin... | 63 | 0.017 | 42 | 37 | 56 | GO:0005901; C:caveola; IDA:BHF-UCL.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005743; C:mitochondrial inner membrane; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0020037; F:heme binding; IDA:UniProtKB.::GO:0005178; F:integrin binding; TAS:BHF-UCL.::GO:0044325; F:ion channel binding; IPI:BHF-UCL.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:BHF-UCL.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0045453; P:bone resorption; ISS:UniProtKB.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IDA:BHF-UCL.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.::GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway; IMP:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0033625; P:positive regulation of integrin activation; TAS:BHF-UCL.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0045124; P:regulation of bone resorption; TAS:BHF-UCL.::GO:0043114; P:regulation of vascular permeability; TAS:BHF-UCL.::GO:0070555; P:response to interleukin-1; IMP:BHF-UCL.::GO:0007172; P:signal complex assembly; TAS:ProtInc.::GO:0031295; P:T cell costimulation; TAS:Reactome. | 394 | Q9WUD9 | 536 | SRC_RAT Proto-oncogene tyrosine-protein kinas... | 63 | 0.018 | 42 | 37 | 56 | GO:0005901; C:caveola; IDA:RGD.::GO:0005829; C:cytosol; NAS:UniProtKB.::GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; IDA:RGD.::GO:0019717; C:synaptosome; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0050839; F:cell adhesion molecule binding; IPI:RGD.::GO:0030331; F:estrogen receptor binding; IPI:RGD.::GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0005158; F:insulin receptor binding; IPI:RGD.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0008022; F:protein C-terminus binding; IPI:RGD.::GO:0005080; F:protein kinase C binding; IPI:RGD. | | | | | | | | | | GO:0032148; P:activation of protein kinase B activity; IMP:UniProtKB.::GO:0034332; P:adherens junction organization; IDA:RGD.::GO:0045453; P:bone resorption; ISS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; IDA:RGD.::GO:0016337; P:cell-cell adhesion; IEP:RGD.::GO:0071398; P:cellular response to fatty acid; IEP:RGD.::GO:0071456; P:cellular response to hypoxia; IEP:RGD.::GO:0032869; P:cellular response to insulin stimulus; IEP:RGD.::GO:0071222; P:cellular response to lipopolysaccharide; IEP:RGD.::GO:0007173; P:epidermal growth factor receptor signaling pathway; IEP:RGD.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; IDA:RGD.::GO:0018105; P:peptidyl-serine phosphorylation; IMP:UniProtKB.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IEP:RGD.::GO:0043065; P:positive regulation of apoptotic process; IDA:RGD.::GO:0045785; P:positive regulation of cell adhesion; IDA:RGD.::GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; IMP:UniProtKB.::GO:0050715; P:positive regulation of cytokine secretion; IMP:RGD.::GO:2000573; P:positive regulation of DNA biosynthetic process; IMP:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.::GO:0010907; P:positive regulation of glucose metabolic process; IMP:RGD.::GO:0046628; P:positive regulation of insulin receptor signaling pathway; IDA:RGD.::GO:0043406; P:positive regulation of MAP kinase activity; IMP:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IMP:UniProtKB.::GO:0010641; P:positive regulation of platelet-derived growth factor receptor signaling pathway; IEP:UniProtKB.::GO:0031954; P:positive regulation of protein autophosphorylation; IMP:UniProtKB.::GO:0014911; P:positive regulation of smooth muscle cell migration; IMP:RGD.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0001101; P:response to acid; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0051602; P:response to electrical stimulus; IEP:RGD.::GO:0042542; P:response to hydrogen peroxide; IEP:RGD.::GO:0009612; P:response to mechanical stimulus; IEP:RGD.::GO:0051385; P:response to mineralocorticoid stimulus; IEP:RGD.::GO:0031667; P:response to nutrient levels; IEP:RGD.::GO:0009615; P:response to virus; IEP:RGD.::GO:0045056; P:transcytosis; IDA:RGD. | 395 | Q9H7D0 | 1870 | DOCK5_HUMAN Dedicator of cytokinesis protein ... | 62 | 0.018 | 42.4 | 37 | 61 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | | 396 | Q13625 | 1128 | ASPP2_HUMAN Apoptosis-stimulating of p53 prot... | 53 | 0.019 | 42.4 | 34 | 51 | GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051059; F:NF-kappaB binding; IPI:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IDA:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; TAS:UniProtKB.::GO:0007165; P:signal transduction; TAS:ProtInc. | 397 | A8MVU1 | 366 | NCF1C_HUMAN Putative neutrophil cytosol facto... | 75 | 0.019 | 41.6 | 29 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0016175; F:superoxide-generating NADPH oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro. | 398 | P42682 | 527 | TXK_MOUSE Tyrosine-protein kinase TXK OS=Mus ... | 51 | 0.019 | 42 | 39 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007202; P:activation of phospholipase C activity; IMP:UniProtKB.::GO:0002250; P:adaptive immune response; IMP:UniProtKB.::GO:0032609; P:interferon-gamma production; IGI:MGI.::GO:0032633; P:interleukin-4 production; IGI:MGI.::GO:0001865; P:NK T cell differentiation; IGI:MGI.::GO:0050852; P:T cell receptor signaling pathway; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 399 | Q95UN8 | 1161 | M3KSL_DROME Mitogen-activated protein kinase ... | 53 | 0.019 | 42.4 | 34 | 58 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004706; F:JUN kinase kinase kinase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; IMP:UniProtKB.::GO:0071361; P:cellular response to ethanol; IMP:FlyBase.::GO:0046843; P:dorsal appendage formation; IMP:FlyBase.::GO:0007394; P:dorsal closure, elongation of leading edge cells; IMP:FlyBase.::GO:0046529; P:imaginal disc fusion, thorax closure; IMP:FlyBase.::GO:0048804; P:imaginal disc-derived female genitalia morphogenesis; IMP:FlyBase.::GO:0048803; P:imaginal disc-derived male genitalia morphogenesis; IMP:FlyBase.::GO:0046330; P:positive regulation of JNK cascade; IMP:FlyBase.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB. | 400 | Q5TCX8 | 1036 | M3KL4_HUMAN Mitogen-activated protein kinase ... | 53 | 0.019 | 42 | 38 | 58 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB. | 401 | Q9VCE9 | 751 | UBS3A_DROME Protein UBASH3A homolog OS=Drosop... | 79 | 0.02 | 42 | 35 | 47 | | | | | | | | | | | | | | | | | | | | | | 402 | A6ZKU1 | 1244 | SLA1_YEAS7 Actin cytoskeleton-regulatory comp... | 93 | 0.02 | 42 | 29 | 48 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 403 | Q9V9J3 | 517 | SRC42_DROME Tyrosine-protein kinase Src42A OS... | 98 | 0.021 | 41.6 | 31 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0051017; P:actin filament bundle assembly; IMP:FlyBase.::GO:0043277; P:apoptotic cell clearance; IMP:FlyBase.::GO:0048749; P:compound eye development; IMP:FlyBase.::GO:0007395; P:dorsal closure, spreading of leading edge cells; IMP:FlyBase.::GO:0046529; P:imaginal disc fusion, thorax closure; IMP:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.::GO:0007254; P:JNK cascade; TAS:FlyBase.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; IGI:FlyBase.::GO:0007424; P:open tracheal system development; IMP:FlyBase.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IMP:FlyBase.::GO:0007435; P:salivary gland morphogenesis; IMP:FlyBase.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IGI:FlyBase.::GO:0006099; P:tricarboxylic acid cycle; IDA:FlyBase. | 404 | Q8BG26 | 893 | RUSC1_MOUSE RUN and SH3 domain-containing pro... | 50 | 0.022 | 42 | 34 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 405 | P32790 | 1244 | SLA1_YEAST Actin cytoskeleton-regulatory comp... | 93 | 0.023 | 42 | 29 | 48 | GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IPI:SGD.::GO:0043130; F:ubiquitin binding; IDA:SGD. | | | | | | | | | | GO:0000147; P:actin cortical patch assembly; TAS:SGD.::GO:0006897; P:endocytosis; IPI:SGD.::GO:0031505; P:fungal-type cell wall organization; TAS:SGD. | 406 | P35991 | 659 | BTK_MOUSE Tyrosine-protein kinase BTK OS=Mus ... | 64 | 0.025 | 41.6 | 31 | 53 | GO:0031410; C:cytoplasmic vesicle; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0048469; P:cell maturation; IMP:MGI.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; IMP:MGI.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 407 | A0JN71 | 380 | SASH3_BOVIN SAM and SH3 domain-containing pro... | 58 | 0.027 | 41.2 | 38 | 50 | | | | | | | | | | | | | | | | | | | | | | 408 | Q04736 | 541 | YES_MOUSE Tyrosine-protein kinase Yes OS=Mus ... | 62 | 0.028 | 41.6 | 37 | 52 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0015758; P:glucose transport; IDA:MGI. | 409 | P55345 | 433 | ANM2_HUMAN Protein arginine N-methyltransfera... | 53 | 0.031 | 41.2 | 34 | 53 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0050681; F:androgen receptor binding; IPI:UniProtKB.::GO:0030331; F:estrogen receptor binding; IDA:UniProtKB.::GO:0008469; F:histone-arginine N-methyltransferase activity; ISS:UniProtKB.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0042975; F:peroxisome proliferator activated receptor binding; IPI:UniProtKB.::GO:0033142; F:progesterone receptor binding; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0042974; F:retinoic acid receptor binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; TAS:ProtInc.::GO:0046966; F:thyroid hormone receptor binding; IPI:UniProtKB.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB. | | | | | | | | | | GO:0048588; P:developmental cell growth; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; IDA:UniProtKB.::GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; IDA:UniProtKB. | 410 | A7TKW4 | 1202 | SLA1_VANPO Actin cytoskeleton-regulatory comp... | 52 | 0.033 | 41.6 | 35 | 56 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 411 | Q6FQJ1 | 603 | VPS27_CANGA Vacuolar protein sorting-associat... | 135 | 0.033 | 41.2 | 24 | 46 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 412 | P59808 | 1230 | SASH1_MOUSE SAM and SH3 domain-containing pro... | 56 | 0.034 | 41.2 | 38 | 48 | | | | | | | | | | | | | | | | | | | | | | 413 | Q60992 | 868 | VAV2_MOUSE Guanine nucleotide exchange factor... | 52 | 0.035 | 41.2 | 35 | 56 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0005154; F:epidermal growth factor receptor binding; IPI:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; IGI:MGI.::GO:0030032; P:lamellipodium assembly; IGI:MGI.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IGI:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IMP:MGI. | 414 | Q6PFY1 | 688 | FCSD1_MOUSE FCH and double SH3 domains protei... | 64 | 0.036 | 41.2 | 34 | 50 | | | | | | | | | | | | | | | | | | | | | | 415 | Q02977 | 536 | YRK_CHICK Proto-oncogene tyrosine-protein kin... | 64 | 0.038 | 40.8 | 31 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 416 | Q9QY53 | 687 | NPHP1_MOUSE Nephrocystin-1 OS=Mus musculus (M... | 56 | 0.038 | 41.2 | 39 | 57 | GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0035085; C:cilium axoneme; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.::GO:0031514; C:motile cilium; ISS:UniProtKB.::GO:0032391; C:photoreceptor connecting cilium; IDA:UniProtKB.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0030030; P:cell projection organization; IMP:UniProtKB.::GO:0034613; P:cellular protein localization; IGI:UniProtKB.::GO:0035845; P:photoreceptor cell outer segment organization; IGI:UniProtKB.::GO:0060041; P:retina development in camera-type eye; IMP:UniProtKB.::GO:0048515; P:spermatid differentiation; IMP:UniProtKB. | 417 | Q8JH64 | 657 | BTK_CHICK Tyrosine-protein kinase BTK OS=Gall... | 57 | 0.043 | 40.8 | 35 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 418 | P52735 | 878 | VAV2_HUMAN Guanine nucleotide exchange factor... | 52 | 0.046 | 40.8 | 35 | 56 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 419 | A8PWF6 | 1322 | MYO1_MALGO Myosin-1 OS=(Dandruff-associated f... | 54 | 0.05 | 40.8 | 35 | 50 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 420 | Q9WV48 | 2167 | SHAN1_RAT SH3 and multiple ankyrin repeat dom... | 68 | 0.05 | 40.8 | 31 | 49 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0060076; C:excitatory synapse; ISS:BHF-UCL.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; ISS:BHF-UCL.::GO:0045211; C:postsynaptic membrane; IDA:RGD. | | | | | | | | | | GO:0071532; F:ankyrin repeat binding; IPI:BHF-UCL.::GO:0030160; F:GKAP/Homer scaffold activity; IDA:BHF-UCL.::GO:0042802; F:identical protein binding; IPI:BHF-UCL.::GO:0035255; F:ionotropic glutamate receptor binding; IPI:RGD.::GO:0008022; F:protein C-terminus binding; IPI:RGD.::GO:0097110; F:scaffold protein binding; IPI:BHF-UCL.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.::GO:0031877; F:somatostatin receptor binding; IPI:UniProtKB. | | | | | | | | | | GO:0008306; P:associative learning; ISS:BHF-UCL.::GO:0007016; P:cytoskeletal anchoring at plasma membrane; NAS:UniProtKB.::GO:0060997; P:dendritic spine morphogenesis; ISS:BHF-UCL.::GO:0007616; P:long-term memory; ISS:BHF-UCL.::GO:0050885; P:neuromuscular process controlling balance; ISS:BHF-UCL.::GO:0060999; P:positive regulation of dendritic spine development; IDA:UniProtKB.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.::GO:0006461; P:protein complex assembly; IDA:BHF-UCL.::GO:0035418; P:protein localization to synapse; ISS:BHF-UCL.::GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:BHF-UCL.::GO:0060074; P:synapse maturation; IDA:UniProtKB. | 421 | P27447 | 544 | YES_XIPHE Tyrosine-protein kinase Yes OS=Xiph... | 108 | 0.051 | 40.4 | 30 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | |
