rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
361 | P14084 | 568 | SRC_AVISS Tyrosine-protein kinase transformin... | 63 | 0.007 | 43.5 | 37 | 56 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 362 | Q8K352 | 380 | SASH3_MOUSE SAM and SH3 domain-containing pro... | 93 | 0.007 | 43.1 | 32 | 44 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | | | | | | | | | | | GO:0048873; P:homeostasis of number of cells within a tissue; IMP:MGI.::GO:0030890; P:positive regulation of B cell proliferation; IMP:MGI.::GO:0043372; P:positive regulation of CD4-positive, alpha-beta T cell differentiation; IMP:MGI.::GO:0002639; P:positive regulation of immunoglobulin production; IMP:MGI.::GO:0032729; P:positive regulation of interferon-gamma production; IMP:MGI.::GO:0032733; P:positive regulation of interleukin-10 production; IMP:MGI.::GO:0032743; P:positive regulation of interleukin-2 production; IMP:MGI.::GO:0032753; P:positive regulation of interleukin-4 production; IMP:MGI.::GO:0046622; P:positive regulation of organ growth; IMP:MGI.::GO:0002726; P:positive regulation of T cell cytokine production; IMP:MGI.::GO:0042102; P:positive regulation of T cell proliferation; IMP:MGI.::GO:0032760; P:positive regulation of tumor necrosis factor production; IMP:MGI. | 363 | Q02779 | 954 | M3K10_HUMAN Mitogen-activated protein kinase ... | 54 | 0.007 | 43.5 | 43 | 59 | GO:0005737; C:cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043425; F:bHLH transcription factor binding; IPI:UniProtKB.::GO:0004706; F:JUN kinase kinase kinase activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; TAS:ProtInc.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0007224; P:smoothened signaling pathway; IMP:UniProtKB. | 364 | P00523 | 533 | SRC_CHICK Proto-oncogene tyrosine-protein kin... | 63 | 0.007 | 43.1 | 37 | 56 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW. | 365 | P00524 | 526 | SRC_RSVSA Tyrosine-protein kinase transformin... | 63 | 0.008 | 43.1 | 37 | 56 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 366 | P00525 | 526 | SRC_AVISR Tyrosine-protein kinase transformin... | 63 | 0.008 | 43.1 | 37 | 56 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 367 | Q4P3H6 | 1207 | SLA1_USTMA Actin cytoskeleton-regulatory comp... | 50 | 0.21 | 38.9 | 34 | 56 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 368 | Q66L42 | 940 | M3K10_MOUSE Mitogen-activated protein kinase ... | 66 | 0.008 | 43.5 | 41 | 55 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0003714; F:transcription corepressor activity; IDA:MGI. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI. | 369 | O74352 | 466 | HOB1_SCHPO Protein hob1 OS=Schizosaccharomyce... | 53 | 0.008 | 43.1 | 42 | 53 | GO:0051285; C:cell cortex of cell tip; TAS:PomBase.::GO:0031097; C:medial cortex; TAS:PomBase. | | | | | | | | | | GO:0051020; F:GTPase binding; NAS:PomBase. | | | | | | | | | | GO:0030702; P:chromatin silencing at centromere; IMP:PomBase.::GO:0006348; P:chromatin silencing at telomere; IMP:PomBase.::GO:0007163; P:establishment or maintenance of cell polarity; IGI:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.::GO:0006974; P:response to DNA damage stimulus; IGI:PomBase.::GO:0000723; P:telomere maintenance; IMP:PomBase. | 370 | P14085 | 557 | SRC_AVIST Tyrosine-protein kinase transformin... | 63 | 0.008 | 43.1 | 37 | 56 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 371 | P27446 | 537 | FYN_XIPHE Tyrosine-protein kinase Fyn OS=Xiph... | 69 | 0.008 | 43.1 | 36 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 372 | Q8N2Y8 | 1516 | RUSC2_HUMAN Iporin OS=Homo sapiens (Human). G... | 50 | 0.009 | 43.1 | 40 | 56 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 373 | Q8TC17 | 118 | GRAPL_HUMAN GRB2-related adapter protein-like... | 49 | 0.009 | 40.4 | 37 | 57 | | | | | | | | | | | | | | | | | | | | | | 374 | P15054 | 587 | SRC_AVIS2 Tyrosine-protein kinase transformin... | 63 | 0.009 | 43.1 | 37 | 56 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 375 | P00526 | 526 | SRC_RSVP Tyrosine-protein kinase transforming... | 63 | 0.01 | 42.7 | 37 | 56 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 376 | P25020 | 526 | SRC_RSVH1 Tyrosine-protein kinase transformin... | 63 | 0.01 | 42.7 | 37 | 56 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 377 | O75044 | 1071 | FNBP2_HUMAN SLIT-ROBO Rho GTPase-activating p... | 73 | 0.01 | 43.1 | 34 | 49 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 378 | P13406 | 537 | FYN_XENLA Tyrosine-protein kinase Fyn OS=Xeno... | 69 | 0.01 | 42.7 | 38 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 379 | Q91Z67 | 1071 | FNBP2_MOUSE SLIT-ROBO Rho GTPase-activating p... | 73 | 0.01 | 43.1 | 34 | 49 | GO:0005743; C:mitochondrial inner membrane; IDA:MGI. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 380 | O94885 | 1247 | SASH1_HUMAN SAM and SH3 domain-containing pro... | 91 | 0.011 | 43.1 | 29 | 44 | | | | | | | | | | | | | | | | | | | | | | 381 | Q64355 | 560 | EFS_MOUSE Embryonal Fyn-associated substrate ... | 70 | 0.011 | 42.7 | 37 | 49 | | | | | | | | | | | GO:0017124; F:SH3 domain binding; IDA:MGI. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 382 | P10936 | 537 | YES_XENLA Tyrosine-protein kinase Yes OS=Xeno... | 106 | 0.011 | 42.7 | 29 | 42 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 383 | Q9DDA9 | 477 | PACN2_XENLA Protein kinase C and casein kinas... | 54 | 0.011 | 42.7 | 43 | 63 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 384 | P00527 | 528 | YES_AVISY Tyrosine-protein kinase transformin... | 79 | 0.011 | 42.7 | 34 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 385 | Q7TNR9 | 484 | ARHG4_MOUSE Rho guanine nucleotide exchange f... | 40 | 0.011 | 42.7 | 43 | 65 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0046847; P:filopodium assembly; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0030032; P:lamellipodium assembly; ISS:UniProtKB.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 386 | Q5I1X5 | 824 | IASPP_MOUSE RelA-associated inhibitor OS=Mus ... | 99 | 0.012 | 42.7 | 32 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0060048; P:cardiac muscle contraction; IMP:MGI.::GO:0003215; P:cardiac right ventricle morphogenesis; IMP:MGI.::GO:0031076; P:embryonic camera-type eye development; IMP:MGI.::GO:0042633; P:hair cycle; IMP:MGI.::GO:0035264; P:multicellular organism growth; IMP:MGI.::GO:0048871; P:multicellular organismal homeostasis; IMP:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0009791; P:post-embryonic development; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0003229; P:ventricular cardiac muscle tissue development; IMP:MGI. | 387 | Q8WUF5 | 828 | IASPP_HUMAN RelA-associated inhibitor OS=Homo... | 99 | 0.013 | 42.7 | 31 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; TAS:ProtInc. | | | | | | | | | | GO:0003714; F:transcription corepressor activity; TAS:ProtInc.::GO:0008134; F:transcription factor binding; TAS:ProtInc. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 388 | P42683 | 508 | LCK_CHICK Proto-oncogene tyrosine-protein kin... | 61 | 0.013 | 42.4 | 39 | 61 | GO:0045121; C:membrane raft; ISS:UniProtKB.::GO:0000242; C:pericentriolar material; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.::GO:0042169; F:SH2 domain binding; ISS:UniProtKB. | | | | | | | | | | GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0006882; P:cellular zinc ion homeostasis; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0050870; P:positive regulation of T cell activation; ISS:UniProtKB.::GO:0042493; P:response to drug; ISS:UniProtKB.::GO:0030217; P:T cell differentiation; ISS:UniProtKB. | 389 | P34416 | 335 | LASP1_CAEEL LIM and SH3 domain protein F42H10... | 53 | 0.014 | 42 | 30 | 60 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 390 | Q08EC4 | 804 | CASS4_MOUSE Cas scaffolding protein family me... | 61 | 0.014 | 42.4 | 33 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 391 | Q5XGP7 | 330 | SKA2A_XENLA Src kinase-associated phosphoprot... | 56 | 0.015 | 42 | 38 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0042113; P:B cell activation; IEA:UniProtKB-KW. |