rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
181 | Q6GM14 | 376 | DBNLB_XENLA Drebrin-like protein B OS=Xenopus... | 65 | 0.000004 | 53.5 | 40 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 182 | O01498 | 457 | STAM1_CAEEL Signal transducing adapter molecu... | 181 | 0.000004 | 53.5 | 27 | 44 | GO:0044441; C:cilium part; IDA:UniProtKB.::GO:0005769; C:early endosome; IDA:WormBase.::GO:0033565; C:ESCRT-0 complex; IPI:WormBase. | | | | | | | | | | GO:0008022; F:protein C-terminus binding; IPI:WormBase.::GO:0043130; F:ubiquitin binding; IDA:WormBase. | | | | | | | | | | GO:0008333; P:endosome to lysosome transport; IMP:WormBase.::GO:0048013; P:ephrin receptor signaling pathway; IGI:UniProtKB.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0043409; P:negative regulation of MAPK cascade; IMP:UniProtKB. | 183 | Q9NYB9 | 513 | ABI2_HUMAN Abl interactor 2 OS=Homo sapiens (... | 56 | 0.000004 | 53.9 | 36 | 64 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0030175; C:filopodium; IDA:UniProtKB.::GO:0030027; C:lamellipodium; IDA:UniProtKB. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; TAS:UniProtKB.::GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0019900; F:kinase binding; NAS:UniProtKB.::GO:0070064; F:proline-rich region binding; IPI:UniProtKB.::GO:0017124; F:SH3 domain binding; IPI:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL. | | | | | | | | | | GO:0008154; P:actin polymerization or depolymerization; NAS:UniProtKB.::GO:0016477; P:cell migration; TAS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:MGI. | 184 | O00160 | 1098 | MYO1F_HUMAN Unconventional myosin-If OS=Homo ... | 54 | 0.000004 | 54.3 | 44 | 61 | GO:0016461; C:unconventional myosin complex; NAS:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; NAS:UniProtKB.::GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0005516; F:calmodulin binding; NAS:UniProtKB.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 185 | O97902 | 1129 | ASAP1_BOVIN Arf-GAP with SH3 domain, ANK repe... | 69 | 0.000004 | 53.9 | 33 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 186 | Q6NRD3 | 826 | SH3R1_XENLA E3 ubiquitin-protein ligase SH3RF... | 59 | 0.0005 | 47 | 36 | 59 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 187 | A7E3N2 | 527 | NCF2_RAT Neutrophil cytosol factor 2 OS=Rattu... | 50 | 0.074 | 40 | 36 | 54 | GO:0005624; C:membrane fraction; IDA:RGD. | | | | | | | | | | | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0032870; P:cellular response to hormone stimulus; IDA:RGD.::GO:0045777; P:positive regulation of blood pressure; IMP:RGD.::GO:0043525; P:positive regulation of neuron apoptotic process; IMP:RGD.::GO:0014823; P:response to activity; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IDA:RGD.::GO:0055093; P:response to hyperoxia; IEP:RGD.::GO:0034616; P:response to laminar fluid shear stress; IEP:RGD.::GO:0033993; P:response to lipid; IEP:RGD.::GO:0032496; P:response to lipopolysaccharide; IDA:RGD.::GO:0014070; P:response to organic cyclic compound; IDA:RGD.::GO:0032570; P:response to progesterone stimulus; IEP:RGD. | 188 | P02549 | 2419 | SPTA1_HUMAN Spectrin alpha chain, erythrocyte... | 81 | 0.000006 | 53.9 | 37 | 51 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0031235; C:intrinsic to internal side of plasma membrane; TAS:BHF-UCL.::GO:0008091; C:spectrin; TAS:ProtInc.::GO:0014731; C:spectrin-associated cytoskeleton; IDA:BHF-UCL. | | | | | | | | | | GO:0051015; F:actin filament binding; TAS:ProtInc.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc. | | | | | | | | | | GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.::GO:0007015; P:actin filament organization; TAS:ProtInc.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW. | 189 | Q14511 | 834 | CASL_HUMAN Enhancer of filamentation 1 OS=Hom... | 58 | 0.000006 | 53.5 | 45 | 59 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; TAS:ProtInc. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0051017; P:actin filament bundle assembly; NAS:UniProtKB.::GO:0007155; P:cell adhesion; NAS:ProtInc.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007229; P:integrin-mediated signaling pathway; NAS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW. | 190 | Q28E95 | 861 | SH3R1_XENTR E3 ubiquitin-protein ligase SH3RF... | 56 | 0.0004 | 47.8 | 39 | 63 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 191 | Q6DFH5 | 335 | SH3Y1_XENLA SH3 domain-containing YSC84-like ... | 70 | 0.000006 | 52.8 | 44 | 51 | | | | | | | | | | | | | | | | | | | | | | 192 | O35177 | 833 | CASL_MOUSE Enhancer of filamentation 1 OS=Mus... | 59 | 0.000006 | 53.5 | 44 | 58 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:MGI.::GO:0000922; C:spindle pole; IDA:MGI. | | | | | | | | | | | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW. | 193 | Q16584 | 847 | M3K11_HUMAN Mitogen-activated protein kinase ... | 73 | 0.000006 | 53.5 | 40 | 53 | GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005874; C:microtubule; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004706; F:JUN kinase kinase kinase activity; ISS:UniProtKB.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; IMP:UniProtKB.::GO:0008283; P:cell proliferation; IMP:UniProtKB.::GO:0000080; P:G1 phase of mitotic cell cycle; IMP:UniProtKB.::GO:0007017; P:microtubule-based process; IMP:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB. | 194 | Q5XXR3 | 772 | ARHG6_RAT Rho guanine nucleotide exchange fac... | 53 | 0.000006 | 53.1 | 43 | 60 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 195 | Q6XZF7 | 1577 | DNMBP_HUMAN Dynamin-binding protein OS=Homo s... | 52 | 0.0003 | 47.8 | 42 | 60 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 196 | O60504 | 671 | VINEX_HUMAN Vinexin OS=Homo sapiens (Human). ... | 66 | 0.047 | 40.8 | 32 | 55 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.::GO:0017166; F:vinculin binding; IPI:UniProtKB. | | | | | | | | | | GO:0006936; P:muscle contraction; TAS:Reactome.::GO:0051496; P:positive regulation of stress fiber assembly; IDA:UniProtKB. | 197 | P46109 | 303 | CRKL_HUMAN Crk-like protein OS=Homo sapiens (... | 83 | 0.014 | 42 | 35 | 49 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.::GO:0004871; F:signal transducer activity; TAS:ProtInc. | | | | | | | | | | GO:0007254; P:JNK cascade; TAS:ProtInc.::GO:0007265; P:Ras protein signal transduction; TAS:ProtInc. | 198 | Q8K4I3 | 771 | ARHG6_MOUSE Rho guanine nucleotide exchange f... | 53 | 0.000007 | 53.1 | 43 | 60 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 199 | P07751 | 2477 | SPTA2_CHICK Spectrin alpha chain, brain OS=Ga... | 223 | 0.000008 | 53.5 | 26 | 41 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051693; P:actin filament capping; IEA:UniProtKB-KW. | 200 | A5D8S5 | 867 | SH3R1_DANRE E3 ubiquitin-protein ligase SH3RF... | 57 | 0.0003 | 47.8 | 40 | 60 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 201 | P10569 | 1168 | MYSC_ACACA Myosin IC heavy chain OS=Acanthamo... | 52 | 0.000008 | 53.1 | 44 | 60 | GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 202 | Q555L8 | 389 | Y4695_DICDI SH3 and FCH domain-containing pro... | 50 | 0.000008 | 52.4 | 42 | 66 | | | | | | | | | | | | | | | | | | | | | | 203 | A5D7F8 | 840 | SH3R1_BOVIN E3 ubiquitin-protein ligase SH3RF... | 50 | 0.002 | 45.4 | 36 | 60 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 204 | Q5RBR0 | 888 | SH3R1_PONAB E3 ubiquitin-protein ligase SH3RF... | 50 | 0.003 | 45.1 | 36 | 60 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 205 | Q5U2U2 | 303 | CRKL_RAT Crk-like protein OS=Rattus norvegicu... | 129 | 0.12 | 38.9 | 29 | 43 | | | | | | | | | | | | | | | | | | | | | | 206 | Q80XI6 | 850 | M3K11_MOUSE Mitogen-activated protein kinase ... | 73 | 0.00001 | 52.8 | 38 | 53 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | | 207 | P47941 | 303 | CRKL_MOUSE Crk-like protein OS=Mus musculus (... | 129 | 0.099 | 39.3 | 29 | 43 | | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0009952; P:anterior/posterior pattern specification; IGI:MGI.::GO:0001568; P:blood vessel development; IGI:MGI.::GO:0007507; P:heart development; IGI:MGI.::GO:0009887; P:organ morphogenesis; IMP:MGI.::GO:0060017; P:parathyroid gland development; IGI:MGI.::GO:0048538; P:thymus development; IGI:MGI. | 208 | Q8IZP0 | 508 | ABI1_HUMAN Abl interactor 1 OS=Homo sapiens (... | 60 | 0.00001 | 52.4 | 35 | 57 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:ProtInc.::GO:0005783; C:endoplasmic reticulum; TAS:ProtInc.::GO:0030175; C:filopodium; IDA:UniProtKB.::GO:0030426; C:growth cone; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; TAS:ProtInc.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008092; F:cytoskeletal protein binding; TAS:ProtInc. | | | | | | | | | | GO:0008154; P:actin polymerization or depolymerization; NAS:UniProtKB.::GO:0006928; P:cellular component movement; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:MGI.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:ProtInc. | 209 | Q66HA1 | 850 | M3K11_RAT Mitogen-activated protein kinase ki... | 73 | 0.00001 | 52.4 | 38 | 53 | GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0004706; F:JUN kinase kinase kinase activity; IDA:RGD.::GO:0031434; F:mitogen-activated protein kinase kinase binding; IPI:RGD.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.::GO:0048365; F:Rac GTPase binding; IPI:RGD. | | | | | | | | | | GO:0008219; P:cell death; IMP:RGD.::GO:0043525; P:positive regulation of neuron apoptotic process; IMP:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD. | 210 | Q7Z6J0 | 888 | SH3R1_HUMAN E3 ubiquitin-protein ligase SH3RF... | 50 | 0.003 | 44.7 | 36 | 60 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.::GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB. | 211 | Q6TXD4 | 1580 | DNMBP_MOUSE Dynamin-binding protein OS=Mus mu... | 57 | 0.0008 | 47 | 37 | 60 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. |