rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
151 | Q14247 | 550 | SRC8_HUMAN Src substrate cortactin OS=Homo sa... | 49 | 0.0000005 | 56.6 | 45 | 63 | GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; TAS:ProtInc.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB.::GO:0005625; C:soluble fraction; TAS:ProtInc. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | | 152 | Q60598 | 546 | SRC8_MOUSE Src substrate cortactin OS=Mus mus... | 49 | 0.0000006 | 56.6 | 45 | 63 | GO:0005938; C:cell cortex; IDA:MGI.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0001726; C:ruffle; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | | 153 | Q01406 | 563 | SRC8_CHICK Src substrate protein p85 OS=Gallu... | 49 | 0.0000007 | 56.2 | 45 | 63 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 154 | Q8IVI9 | 506 | NOSTN_HUMAN Nostrin OS=Homo sapiens (Human). ... | 100 | 0.0000008 | 55.8 | 36 | 50 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030666; C:endocytic vesicle membrane; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0046209; P:nitric oxide metabolic process; TAS:Reactome.::GO:0050999; P:regulation of nitric-oxide synthase activity; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 155 | Q96HL8 | 342 | SH3Y1_HUMAN SH3 domain-containing YSC84-like ... | 52 | 0.0000008 | 55.5 | 48 | 63 | | | | | | | | | | | | | | | | | | | | | | 156 | O77775 | 527 | NCF2_BOVIN Neutrophil cytosol factor 2 OS=Bos... | 50 | 0.086 | 39.7 | 36 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | | 157 | Q557J6 | 481 | DBNL_DICDI Drebrin-like protein OS=Dictyostel... | 54 | 0.0000009 | 55.8 | 44 | 70 | GO:0031252; C:cell leading edge; IDA:dictyBase.::GO:0030864; C:cortical actin cytoskeleton; IDA:dictyBase.::GO:0005615; C:extracellular space; IDA:dictyBase.::GO:0097203; C:phagocytic cup lip; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.::GO:0031143; C:pseudopodium; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; ISS:dictyBase.::GO:0032037; F:myosin I heavy chain binding; IPI:dictyBase.::GO:0005522; F:profilin binding; IPI:dictyBase.::GO:0019901; F:protein kinase binding; IPI:dictyBase. | | | | | | | | | | GO:0006928; P:cellular component movement; IMP:dictyBase.::GO:0050765; P:negative regulation of phagocytosis; IMP:dictyBase.::GO:0031269; P:pseudopodium assembly; IMP:dictyBase. | 158 | Q5RAQ2 | 342 | SH3Y1_PONAB SH3 domain-containing YSC84-like ... | 52 | 0.0000009 | 55.1 | 48 | 63 | | | | | | | | | | | | | | | | | | | | | | 159 | O13821 | 610 | VPS27_SCHPO Vacuolar protein sorting-associat... | 146 | 0.000001 | 55.8 | 30 | 47 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0033565; C:ESCRT-0 complex; IPI:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005628; C:prospore membrane; IDA:PomBase. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; ISS:PomBase.::GO:0043130; F:ubiquitin binding; IMP:PomBase. | | | | | | | | | | GO:0031321; P:ascospore-type prospore assembly; IGI:PomBase.::GO:0006897; P:endocytosis; IMP:PomBase.::GO:0006900; P:membrane budding; IC:PomBase.::GO:0045053; P:protein retention in Golgi apparatus; ISS:PomBase.::GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:PomBase. | 160 | Q8R1B0 | 408 | STAC2_MOUSE SH3 and cysteine-rich domain-cont... | 51 | 0.000002 | 54.7 | 35 | 67 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 161 | Q6ZMT1 | 411 | STAC2_HUMAN SH3 and cysteine-rich domain-cont... | 51 | 0.000002 | 54.7 | 35 | 67 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 162 | P87378 | 296 | CRK_XENLA Adapter molecule crk OS=Xenopus lae... | 84 | 3.9 | 34.3 | 31 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB. | 163 | P34109 | 1109 | MYOD_DICDI Myosin ID heavy chain OS=Dictyoste... | 57 | 0.000002 | 55.1 | 40 | 60 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0031252; C:cell leading edge; IDA:dictyBase.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.::GO:0031143; C:pseudopodium; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0006909; P:phagocytosis; IEA:UniProtKB-KW. | 164 | Q6CL17 | 603 | VPS27_KLULA Vacuolar protein sorting-associat... | 139 | 0.000002 | 54.7 | 26 | 47 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 165 | Q9URW6 | 430 | YIE2_SCHPO SH3 domain-containing protein PJ69... | 52 | 0.000002 | 54.3 | 42 | 65 | GO:0030479; C:actin cortical patch; ISS:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0007015; P:actin filament organization; ISS:PomBase.::GO:0006897; P:endocytosis; ISS:PomBase. | 166 | Q04929 | 305 | CRK_CHICK Adapter molecule crk OS=Gallus gall... | 84 | 3.4 | 34.3 | 31 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB. | 167 | P62484 | 446 | ABI2_MOUSE Abl interactor 2 OS=Mus musculus (... | 58 | 0.000002 | 54.3 | 36 | 64 | GO:0005913; C:cell-cell adherens junction; IDA:MGI.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030425; C:dendrite; IDA:MGI.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0043010; P:camera-type eye development; IMP:MGI.::GO:0016477; P:cell migration; IMP:MGI.::GO:0016358; P:dendrite development; IMP:MGI.::GO:0007611; P:learning or memory; IMP:MGI. | 168 | P70248 | 1099 | MYO1F_MOUSE Unconventional myosin-If OS=Mus m... | 54 | 0.000003 | 54.7 | 43 | 61 | GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 169 | Q5DU57 | 656 | SPT13_MOUSE Spermatogenesis-associated protei... | 54 | 0.000003 | 54.7 | 48 | 61 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0030175; C:filopodium; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0032587; C:ruffle membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0046847; P:filopodium assembly; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0030032; P:lamellipodium assembly; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 170 | Q58DL7 | 561 | ARHG9_BOVIN Rho guanine nucleotide exchange f... | 112 | 0.000003 | 54.3 | 31 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 171 | O70145 | 525 | NCF2_MOUSE Neutrophil cytosol factor 2 OS=Mus... | 50 | 0.096 | 39.7 | 36 | 54 | GO:0001669; C:acrosomal vesicle; IDA:MGI. | | | | | | | | | | GO:0048365; F:Rac GTPase binding; IPI:MGI. | | | | | | | | | | GO:0042554; P:superoxide anion generation; IDA:MGI. | 172 | Q9QZM5 | 476 | ABI1_RAT Abl interactor 1 OS=Rattus norvegicu... | 60 | 0.000003 | 54.3 | 37 | 58 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.::GO:0030426; C:growth cone; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 173 | P08032 | 2415 | SPTA1_MOUSE Spectrin alpha chain, erythrocyte... | 157 | 0.000003 | 54.7 | 29 | 43 | GO:0032437; C:cuticular plate; IDA:MGI.::GO:0016020; C:membrane; IDA:MGI.::GO:0008091; C:spectrin; IMP:MGI.::GO:0014731; C:spectrin-associated cytoskeleton; IMP:MGI. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0046982; F:protein heterodimerization activity; IPI:MGI. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IMP:MGI.::GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.::GO:0030097; P:hemopoiesis; IMP:MGI.::GO:0002260; P:lymphocyte homeostasis; IMP:MGI.::GO:0007009; P:plasma membrane organization; IMP:MGI.::GO:0006779; P:porphyrin-containing compound biosynthetic process; IMP:MGI.::GO:0042102; P:positive regulation of T cell proliferation; IMP:MGI.::GO:0008360; P:regulation of cell shape; IMP:MGI. | 174 | Q8I7C3 | 657 | LASP1_DROME LIM and SH3 domain protein Lasp O... | 60 | 0.000003 | 54.3 | 42 | 65 | GO:0005925; C:focal adhesion; IDA:FlyBase.::GO:0070864; C:sperm individualization complex; IDA:FlyBase. | | | | | | | | | | GO:0003779; F:actin binding; IDA:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007279; P:pole cell formation; IMP:FlyBase.::GO:0045856; P:positive regulation of pole plasm oskar mRNA localization; IMP:FlyBase.::GO:0007291; P:sperm individualization; IMP:FlyBase. | 175 | B0BNA1 | 340 | SH3Y1_RAT SH3 domain-containing YSC84-like pr... | 52 | 0.000003 | 53.5 | 48 | 62 | | | | | | | | | | | | | | | | | | | | | | 176 | Q3UTH8 | 516 | ARHG9_MOUSE Rho guanine nucleotide exchange f... | 112 | 0.000003 | 53.9 | 31 | 44 | GO:0005938; C:cell cortex; TAS:MGI. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:MGI. | 177 | O08641 | 340 | SH3Y1_MOUSE SH3 domain-containing YSC84-like ... | 52 | 0.000003 | 53.5 | 48 | 62 | | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 178 | O43307 | 516 | ARHG9_HUMAN Rho guanine nucleotide exchange f... | 112 | 0.000003 | 53.9 | 31 | 44 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0034220; P:ion transmembrane transport; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome. | 179 | Q8CBW3 | 481 | ABI1_MOUSE Abl interactor 1 OS=Mus musculus (... | 60 | 0.000004 | 53.9 | 37 | 58 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.::GO:0030426; C:growth cone; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0030296; F:protein tyrosine kinase activator activity; IDA:MGI. | | | | | | | | | | GO:0001756; P:somitogenesis; IMP:MGI. | 180 | Q9R1Z8 | 733 | VINEX_MOUSE Vinexin OS=Mus musculus (Mouse). ... | 51 | 0.1 | 39.7 | 35 | 57 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0008134; F:transcription factor binding; IPI:MGI. | | | | | | | | | | GO:0031589; P:cell-substrate adhesion; IDA:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0043410; P:positive regulation of MAPK cascade; IDA:MGI. | 181 | Q6GM14 | 376 | DBNLB_XENLA Drebrin-like protein B OS=Xenopus... | 65 | 0.000004 | 53.5 | 40 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | |